Abstract: The present invention relates to novel matriptase inhibitors.

Abstract: The invention relates to co-activated silicate based phosphors and a process for preparing these phosphors and the use of these phosphors in electronic and electrooptical devices, especially light emitting diodes (LEDs) and solar cells. The invention further relates to illumination units comprising said phosphors.

Abstract: Compounds of the formula I in which R1 and R2 have the meanings indicated in Claim 1, are inhibitors of GCN2, and can be employed, inter alia, for the treatment of cancer.

Abstract: The present invention relates to a layer arrangement which changes the transmission of light depending on its temperature, where the layer arrangement has a first polarization layer, a switching layer which influences the polarization properties of light depending on the temperature, and a second polarization layer, as well as an additional NIR transmission-preventing layer.

Abstract: 1H-Pyrrolo[2,3-b]pyridine compounds are inhibitors of cell proliferation/cell vitality and can be employed for the treatment of tumours.

Abstract: The present invention relates to effect pigments based on coated, flake-form substrates, where an organic coating which contains fluoroalkyl groups and hydrophilic groups and is built up from at least one siloxane and/or at least one silane is applied to the substrate as outer layer.

Abstract: The present invention relates to a switch element, which is thermoresponsive and which switches between a less transmissive state for radiant energy and a more transmissive state for radiant energy, and which comprises a liquid-crystalline medium. The invention furthermore relates to the use of the switch element for the regulation of radiant energy flow between interior spaces and the environment and for the regulation of the temperature of interior spaces. The invention furthermore relates to a liquid-crystalline medium, characterized in that it comprises a compound of the formula (I), in particular for use in the switch elements according to the invention.

Abstract: The invention relates to the use of specific glucuronolactone derivatives as self-tanning substances, as tanning enhancers for dihydroxyacetone or for a mixture of self-tanning substances comprising dihydroxyacetone, for modulation of the hue achieved in the case of tanning with dihydroxyacetone or by the mixture or preparation comprising dihydroxyacetone, as contrast-reduction agents or for colouring keratin-containing fibres, and to preparations or compositions for colouring keratin-containing fibres comprising these specific glucuronolactone derivatives.

Abstract: The present invention relates to phosphorescent organic electroluminescent devices include at least one phosphorescent emitter and a matrix material in the emitting layer, where certain conditions must be satisfied for the positions of the triplet energy and the HOMO and LUMO.

Abstract: Arylpyrazinone derivatives of formula (I), as insulin secretion stimulators, the preparation and use of these pyrazinone derivatives for the prophylaxis and/or treatment of diabetes and pathologies associated.

Abstract: The invention relates to a liquid-crystalline medium based on a mixture of polar compounds having a negative dielectric anisotropy which contains at least one self-aligning additive, especially at least one additive selected from the group of the compounds of the formula IA to ID in which R1A, R1B, R1C, L1-12, R1D, Ring l, u, v, w, x, y, z and m have the meanings indicated in Claim 4 and to the use thereof for an active-matrix display, in particular based on the VA, PSA and PS-VA effect in LC displays.

Abstract: The invention relates to novel dinaphtho[2,3-a:2?,3?-h]phenazine compounds, to methods for their preparation and intermediates used therein, formulations comprising them, the use of these compounds and formulations as semiconductor material in organic electronic (OE) devices, and OE devices comprising these compounds and formulations.

Abstract: The present invention relates to liquid-crystal media and liquid-crystal displays (LC displays) comprising these media with homeotropic (vertical) alignment of the liquid-crystalline medium (LC medium). The LC medium having positive dielectric anisotropy according to the invention comprises particles having a mass of at least 450 Da which have been functionalised by a polar, organic anchor group. It is preferably stabilised by a polymerisable component.

Abstract: The present invention relates to polymeric materials which have electron-transporting, hole-transporting and/or emitting units in the side chains. The present invention furthermore relates to processes for the preparation of these polymers, to the use of these polymers in electroluminescent devices and to electroluminescent devices comprising these polymers.

Abstract: The present invention relates to a liquid-crystal medium which comprises a component A which consists of one or more compounds of the formula I in which the parameters have the respective meanings given in the claims or in the text, and to the corresponding, novel mesogenic compounds and to the preparation thereof. The present invention likewise relates to the use of these liquid-crystal media, in particular in components for high-frequency technology, and to components of this type which contain media according to the invention, and to the production and use of these components. The components according to the invention are suitable, in particular, as phase shifters in the microwave and millimetre wave region, for microwave and millimetre wave array antennae and very particularly for so-called tuneable “reflectarrays”.

Abstract: A reloadable auto injector for epinephrine injection is provided. The reloadable auto injector has a separate needle insertion and medicine injection drivers (1600) wherein needle insertion driver (1200) is configured to be re-activated upon reloading. A syringe is movably positioned in a housing between a first position in which the needle is accommodated inside the housing and a second position in which the needle protrudes outside the housing. A plunger rod (1500) is normally locked to a plunger rod tube (1100) by at least one deflectable locking member (1110). A syringe driver (1200) applies a force to the syringe to move the syringe together with plunger rod tube, plunger rod and plunger rod driver from the first position to the second position. In the second position, the locking member (1110) is unlocked and releases the plunger rod to thereby activate the plunger rod driver to advance the plunger rod in the syringe for delivering of medicament.

Abstract: Compounds of the formula I in which X, R1 and R2 have the meanings indicated in Claim 1, are inhibitors of GCN2, and can be employed, inter alia, for the treatment of cancer.

Abstract: The present invention relates to electronic devices comprising at least one compound of the formula (1) where X is N and Y is CR1, and to the use thereof.

Abstract: The present invention relates to novel acetylene derivatives as positive allosteric modulators for modulating metabotropic glutamate receptor subtype 4 (mGluR4) and/or altering glutamate level or glutamatergic signalling.

Abstract: The present invention relates to compounds of formula (I) Wherein R1, R2, R3, R4, L and Z have the meaning given in claim 1, and their use in the prophylaxis and treatment of diseases.