Patents Assigned to Merck Patents GmbH
  • PYRIDAZINONE-AMIDES DERIVATIVES
    Publication number: 20150376167
    Abstract: The present invention relates to compounds of formula (I) wherein R1, Ra, Rb and Z have the meaning given in claim 1, and their use in the prophylaxis and treatment of diseases.
    Type: Application
    Filed: February 6, 2014
    Publication date: December 31, 2015
    Applicant: Merck Patent GmbH
    Inventors: Catherine JORAND-LEBRUN, Santosh KULKARNI, Stefano CROSIGNANI
  • Peptide for use in the treatment of breast cancer and/or bone metastases
    Patent number: 9220771
    Abstract: The invention relates to the use of the Peptide of the formula Cyclo-(Arg-Gly-Asp-DPhe-NMe-Val) and/or the pharmaceutically acceptable derivatives, solvates and/or salts thereof, for the manufacture of a medicament for the treatment of breast cancer and/or bone metastases in humans, wherein the medicament is optionally to be used in combination with one or more cancer cotherapeutic agents, preferably selected from a) hormone modulating agents, b) osteoclast activity modulating agents, c) cancer chemotherapeutic agents, and/or d) radiotherapy, alone, concurrently or not in the dosage regime of the present invention.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: December 29, 2015
    Assignee: MERCK PATENT GMBH
    Inventors: Anne Kerber, Tobias Baeuerle
  • 2-(heterocyclylbenzyl)pyridazinone derivatives
    Patent number: 9221806
    Abstract: Compounds of the formula (I), in which R1, R2, R3, R4 and R5 have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumors.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: December 29, 2015
    Assignee: Merck Patent GmbH
    Inventors: Dieter Dorsch, Oliver Schadt, Andree Blaukat, Frank Stieber
  • Compounds having electron transport properties, their preparation and use
    Patent number: 9221770
    Abstract: The invention provides new compounds of the formula I, II or III. These compounds can be used as electron transport materials in optical light emitting diodes (OLEDs).
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: December 29, 2015
    Assignee: Merck Patent GmbH
    Inventors: Poopathy Kathirgamanathan, Sivagnanasundram Surendrakumar, Yun Fu Chan
  • PIPERIDINYLCARBAZOLES
    Publication number: 20150368226
    Abstract: The present invention provides compounds of Formula (I) for the treatment of parasitic diseases including malaria, as well as neurodegenerative diseases. Formula (I) wherein R3, R4, X and Y have the meaning given in claim 1.
    Type: Application
    Filed: December 27, 2013
    Publication date: December 24, 2015
    Applicant: Merck Patent GmbH
    Inventors: Julie ROUTIER, Thomas SPANGENBERG
  • BIREFRINGENT RM LENS
    Publication number: 20150369982
    Abstract: The invention relates to a RM lens obtainable from a polymerizable liquid crystalline medium comprising, a polymerizable liquid crystalline component A comprising one or more polymerizable mesogenic compounds, and at most 12% by weight of the total medium of a non-mesogenic component B. Moreover, the invention relates to the use of such birefringent RM lenses in electro optical devices, such as liquid crystal displays (LCDs) or other optical or electrooptical devices, for decorative or security applications.
    Type: Application
    Filed: December 4, 2013
    Publication date: December 24, 2015
    Applicant: Merck Patent GmbH
    Inventor: Joseph SARGENT
  • SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AS AGGRECANASE INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS
    Publication number: 20150368188
    Abstract: The present invention relates to compounds of the formula I and in particular medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which ADAMTS5 is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, hepatocirrhosis, traumatic cartilage injuries, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: January 16, 2014
    Publication date: December 24, 2015
    Applicant: MERCK PATENT GMBH
    Inventors: Markus KLEIN, Sven LINDEMANN
  • PROCESS FOR THE PRODUCTION OF THREE-DIMENSIONAL PATTERNS IN PLASTIC MOULDINGS
    Publication number: 20150367543
    Abstract: The present invention relates to a process for the production of three-dimensional patterns in plastic mouldings, in particular to an injection-moulding process for the production of mouldings having a three-dimensional pattern, to the polymeric mouldings produced by means of this process, and to the use thereof, in particular for decorative purposes.
    Type: Application
    Filed: June 23, 2015
    Publication date: December 24, 2015
    Applicant: MERCK PATENT GMBH
    Inventors: Markus SCHUM, Rainer LINZMEIER
  • Materials for organic electroluminescent devices
    Patent number: 9217006
    Abstract: The present invention relates to transition-metal complexes of the general formula I or II, in particular as emitter molecules in organic electronic devices, to a layer and to an electronic device which comprise the compounds according to the invention, and to a process for the preparation of the compounds according to the invention.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: December 22, 2015
    Assignee: Merck Patent GmbH
    Inventors: Amir Hossain Parham, Arne Buesing, Anja Gerhard, Joachim Kaiser, Rocco Fortte
  • Polymer-stabilised liquid-crystal media and displays
    Patent number: 9217109
    Abstract: The present invention relates to liquid-crystalline media and display devices comprising polymerizable compounds, to the use of the polymerizable compounds for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays having a polymer-stabilized blue phase, and in LC media for LC displays of the PS or PSA (“polymer sustained” or “polymer sustained alignment”) type. The polymerizable compounds comprise a ring system which is functionalized by three or more polymerizable groups, each connected via an optional spacer group.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: December 22, 2015
    Assignee: MERCK PATENT GmbH
    Inventors: Axel Jansen, Thorsten Kodek, Helmut Haensel, Erdal Durmaz, Julia Sprang
  • Process for preparing benzo[1,2-b;4,5-b?]dithiophene-4,8-dicarboxylic acid or its 2,3-dihydro derivative
    Patent number: 9216994
    Abstract: The invention relates to a process for preparing benzo[1,2-b;4,5-b?]dithiophene-4,8-dicarboxylic acid or its 2,3-dihydro derivative, and to novel products prepared by this process.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: December 22, 2015
    Assignee: Merck Patent GmbH
    Inventor: Eva Kriegbaum
  • ACYLGUANIDINES FOR TREATING OSTEOARTHRITIS
    Publication number: 20150361037
    Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: December 16, 2013
    Publication date: December 17, 2015
    Applicant: Merck Patent GmbH
    Inventors: Christos TSAKLAKIDIS, Markus KLEIN, Paul CZODROWSKI
  • POSITIVE ALLOSTERIC MODULATORS OF MGLUR3
    Publication number: 20150361046
    Abstract: The present invention relates to novel substituted pyridine derivatives as positive allosteric modulators for modulating metabotropic glutamate receptor subtype 3 (mGluR3) and/or altering glutamate level or glutamatergic signalling.
    Type: Application
    Filed: January 22, 2014
    Publication date: December 17, 2015
    Applicant: Merck Patent GmbH
    Inventor: Justin POTNICK
  • Spiro-Quinazolinone Derivatives and their Use as Positive Allosteric Modulators of mGluR4
    Publication number: 20150361079
    Abstract: The present invention relates to novel spiro-quinazolinone derivatives as positive allosteric modulators for modulating metabotropic glutamate receptor subtype 4 (mGluR4) and/or altering glutamate level or glutamatergic signalling.
    Type: Application
    Filed: January 23, 2014
    Publication date: December 17, 2015
    Applicant: Merck Patent GMBH
    Inventors: Nadia BRUGGER, Brian L. HODOUS, Amanda E. SUTTON, Justin POTNICK, Theresa L. JOHNSON, Thomas E. RICHARDSON, Thomas Francis Nelson HAXELL, James M. DORSEY, Robert James FOGLESONG
  • 2 AMINO-3,4-DIHYDRCQUINAZOLINE DERIVATIVES AND THE USE THEREOF AS CATHEPSIN D INHIBITORS
    Publication number: 20150361053
    Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: January 20, 2014
    Publication date: December 17, 2015
    Applicant: Merck Patent GmbH
    Inventors: Markus KLEIN, Christos TSAKLAKIDIS
  • Liquid crystalline medium and liquid crystalline display
    Patent number: 9212309
    Abstract: The present invention relates to dielectrically positive liquid-crystalline media comprising one or more compounds of the formula I in which the parameters have the respective meanings indicated in the specification, and optionally one or more further dielectrically positive compounds and optionally one or more further dielectrically neutral compounds, and to liquid-crystal displays containing these media, especially to active-matrix displays and in particular to TN, IPS and FFS displays.
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: December 15, 2015
    Assignee: Merck Patent GmbH
    Inventors: Markus Czanta, Harald Hirschmann, Sven Baran, Lars Lietzau
  • Metal complexes
    Patent number: 9212198
    Abstract: The present invention relates to metal complexes having high solubility and to electronic devices, in particular organic electroluminescent devices, containing these metal complexes.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: December 15, 2015
    Assignee: Merck Patent GmbH
    Inventors: Adam W. Franz, Rémi Manouk Anémian
  • Polymers of 8,9-dihydrobenzo[]carbazole and their use as organic semiconductors
    Patent number: 9212260
    Abstract: The invention relates to novel polymers containing 8,9-dihydrobenzo[def]carbazole units, methods and materials for their preparation, their use as semiconductors in organic electronic (OE) devices, and to OE devices comprising these polymers.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: December 15, 2015
    Assignee: MERCK PATENT GMBH
    Inventors: Nicolas Blouin, William Mitchell, Changsheng Wang, Steven Tierney
  • Liquid-crystal display
    Patent number: 9212311
    Abstract: The present invention relates to the use of LC (liquid-crystal) compounds and LC media comprising them in LC displays of the PS (polymer stabilized) or PSA (polymer sustained alignment) type.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: December 15, 2015
    Assignee: Merck Patent GmbH
    Inventors: Seung-Eun Lee, Eun Young Kim, Dong-Mee Song, Eun-Kyu Lee
  • 2-AMINOPYRIDINE COMPOUNDS
    Publication number: 20150353548
    Abstract: The invention provides novel substituted 2-aminopyridine compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases such as cancer, inflammatory or degenerative diseases.
    Type: Application
    Filed: October 2, 2013
    Publication date: December 10, 2015
    Applicants: CANCER RESEARCH TECHNOLOGY LIMITED, MERCK PATENT GMBH
    Inventors: Kai SCHIEMANN, Frank STIEBER, Julian BLAGG, Aurelie MALLINGER, Dennis WAALBOER, Christian RINK, Simon Ross CRUMPLER