Patents Assigned to Merck Patents GmbH
  • Patent number: 10081637
    Abstract: The present invention relates to pyrazole compounds, and pharmaceutically acceptable compositions thereof, useful as positive allosteric modulators of follicle stimulating hormone receptor (FSHR).
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: September 25, 2018
    Assignee: Merck Patent GmbH
    Inventors: Henry Yu, Marianne Donnelly, Ngan Nguyen, Xuliang Jiang
  • Publication number: 20180265785
    Abstract: The present invention relates to liquid-crystalline media comprising a) one or more compounds of the formula ST-1, as defined herein, and b) one or more compounds of the formula ST-2, as defined herein, and c) one or more compounds of the formula RV, as defined herein, and d) one or more compounds selected from formula IA and IB, as defined herein, and to liquid-crystal displays containing these media, especially to displays addressed by an active matrix and in particular to displays of the in-plane switching (IPS) or fringe-field switching (FFS) type.
    Type: Application
    Filed: March 16, 2018
    Publication date: September 20, 2018
    Applicant: Merck Patent GmbH
    Inventors: Chang-Jun YUN, Chang-Suk CHOI, Yeon-Jeong HAN, Heui-Seok JIN, Yong-Kuk YUN
  • Publication number: 20180269398
    Abstract: The invention relates to arylamino compounds and to the use thereof in electronic devices, for example organic electroluminescent devices. The invention furthermore relates to electronic devices comprising one or more of the said compounds, for example as hole-transport materials in a corresponding functional layer of the device. The invention furthermore relates to a process for the preparation of the said compounds, and to a formulation comprising one or more of the said compounds.
    Type: Application
    Filed: May 23, 2018
    Publication date: September 20, 2018
    Applicant: Merck Patent GmbH
    Inventors: Philipp Stoessel, Frank Voges, Arne Buesing, Christof Pflumm, Teresa Mujica-Fernaud, Christian Wirges
  • Publication number: 20180265786
    Abstract: Liquid-crystalline media containing a) one or more compounds of formula IA, and b) one or more compounds of formula II and c) one or more compounds of formulae III-1 to III-4, their use in electro-optical displays, particularly in active-matrix displays based on the VA, ECB, FFS or IPS effect.
    Type: Application
    Filed: March 16, 2018
    Publication date: September 20, 2018
    Applicant: MERCK PATENT GMBH
    Inventors: Chang-Suk Choi, Chang-Jun Yun, Yeon-Jeong Han, Heui-Seok Jin, Yong-Kuk Yun
  • Publication number: 20180265784
    Abstract: A liquid-crystalline medium which comprises at least one compound of the formula I, and one or more compounds of the formula ST and to the use thereof for an active-matrix display, in particular based on the VA, PSA, PA-VA, SS-VA, SA-VA, PS-VA, PALC, IPS, PS-IPS, UB-FFS, U-IPS, FFS or PS-FFS effect.
    Type: Application
    Filed: March 16, 2018
    Publication date: September 20, 2018
    Applicant: MERCK PATENT GMBH
    Inventors: Chang-Suk CHOI, Chang-Jun YUN, Yeon-Jeong HAN, Heui-Seok JIN, Yong-Kuk YUN
  • Publication number: 20180265708
    Abstract: Disclosed are pigment powders containing only coated BiOCl flakes, which flakes area) BiOCl flakes having a coating containing yellow iron oxide Fe2O3*xH2O, optionally a colorant, optionally an adjuvant, and optionally SiO2, b) BiOCl flakes having a coating containing SiO2, optionally a colorant, and optionally an adjuvant, c) BiOCl flakes having a coating containing a colorant, SiO2, optionally yellow iron oxide Fe2O3*xH2O, and optionally an adjuvant, or d) BiOCl flakes having a coating containing Fe3O4 and optionally SiO2, to a process for the preparation of the pigment powders, and to the use thereof especially in cosmetic formulations.
    Type: Application
    Filed: March 19, 2018
    Publication date: September 20, 2018
    Applicant: Merck Patent GmbH
    Inventors: Padma KAVIRATNA, Mark TELLEFSEN, Qingmin CHENG, Matthew EDDENS, Qinyun PENG
  • Publication number: 20180269399
    Abstract: The invention relates to arylamino compounds and to the use thereof in electronic devices, for example organic electroluminescent devices. The invention furthermore relates to electronic devices comprising one or more of the said compounds, for example as hole-transport materials in a corresponding functional layer of the device. The invention furthermore relates to a process for the preparation of the said compounds, and to a formulation comprising one or more of the said compounds.
    Type: Application
    Filed: May 23, 2018
    Publication date: September 20, 2018
    Applicant: Merck Patent GmbH
    Inventors: Philipp Stoessel, Frank Voges, Arne Buesing, Christof Pflumm, Teresa Mujica-Fernaud, Christian Wirges
  • Patent number: 10077288
    Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries arthritis, pain, allodynia or hyperalgesia.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: September 18, 2018
    Assignee: Merck Patent GmbH
    Inventors: Christos Tsaklakidis, Markus Klein
  • Publication number: 20180258346
    Abstract: The present invention relates to liquid-crystalline media (LC media) comprising a low-molecular-weight component, a self-alignment additive comprising a thiol group and optionally a polymerizable component. The self-alignment additives effect homeotropic (vertical) alignment of the LC media at a surface or the cell walls of a liquid-crystal display (LC display). The invention therefore also encompasses LC displays having homeotropic alignment of the liquid-crystalline medium (LC medium) without alignment layers. The invention discloses novel structures for self-alignment additives which have a thiol functional groups.
    Type: Application
    Filed: August 16, 2016
    Publication date: September 13, 2018
    Applicant: MERCK PATENT GMBH
    Inventors: Yong-Kuk YUN, Min-Ok JIN, Hyun-Jin YOON, Mi-Nam PARK, Rocco FORTTE, Graziano ARCHETTI, Thorsten KODEK, Izumi SAITO
  • Publication number: 20180258289
    Abstract: The present invention relates to coated zinc sulfide pigments and to the use thereof, preferably in paints, automotive paints, industrial coatings, powder coatings, plastics, printing inks, ceramic glazes and cosmetic formulations, and to a process for the preparation thereof.
    Type: Application
    Filed: July 29, 2016
    Publication date: September 13, 2018
    Applicant: MERCK PATENT GMBH
    Inventors: Helge Bettina KNIESS, Ulrich QUITTMANN, Oliver Robert PIENING
  • Publication number: 20180258115
    Abstract: The invention relates to Brønsted-acidic fluoroalkyl phosphonates as bifunctional catalysts and to processes for the preparation thereof.
    Type: Application
    Filed: August 30, 2016
    Publication date: September 13, 2018
    Applicant: Merck Patent GmbH
    Inventors: Nikolai (Mykola) IGNATIEV, Peter BARTHEN, Bernd BREDENHAGEN, Michaela Katharina MEYER, Walter FRANK
  • Publication number: 20180261768
    Abstract: The present invention relates compositions comprising an organic semiconducting material, a solvent, and specifically selected polymer particles, which allow modifying the viscosity of such compositions. The present application further relates to the use of such compositions in the production of organic electronic devices.
    Type: Application
    Filed: July 11, 2016
    Publication date: September 13, 2018
    Applicant: Merck Patent GmbH
    Inventors: Lichun CHEN, Andromachi MALANDRAKI
  • Publication number: 20180258082
    Abstract: The present invention relates to the compounds of the formula (1) and to organic electroluminescent devices, in particular blue-emitting devices, in which these compounds are used as host material or dopant in the emitting layer and/or as hole-transport material and/or as electron-transport material.
    Type: Application
    Filed: July 15, 2016
    Publication date: September 13, 2018
    Applicant: Merck Patent GmbH
    Inventors: Holger Heil, Beate Burkhart, Lara-Isabel Rodriguez, Sebastian Meyer, Rouven Linge, Amandine Darsy
  • Patent number: 10072210
    Abstract: The invention relates to a liquid-crystalline medium, having particular dielectric properties, in that it has: either a dielectric constant perpendicular to the director (??) in the range of 2 or more to less 8 or less and at the same time a ratio of the dielectric constant perpendicular to the director (??) to the dielectric anisotropy (??), i.e. (??/??) of 1.0 or more or or a dielectric constant perpendicular to the director (??) of 8 or more and a dielectric anisotropy (??) of 26 or less and preferably comprises one or more compounds having a high dielectric constant perpendicular to the director (??) and a high average dielectric constant (?av.). These compounds are suitable for use in an electro-optical display, particularly in an active-matrix display based on the IPS or FFS effect.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: September 11, 2018
    Assignee: MERCK PATENT GMBH
    Inventor: Atsutaka Manabe
  • Patent number: 10072092
    Abstract: Anti-CD19 B4 antibodies with modified variable regions are disclosed. The modified anti-CD19 variable region polypeptides have alterations to one or more framework regions or complementarity determining regions of the heavy chain variable region or light chain variable region, thereby to reduce a T-cell response.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: September 11, 2018
    Assignee: Merck Patent GmbH
    Inventors: Michael Super, Jonathan Davis, Pascal Andre Stein
  • Patent number: 10074807
    Abstract: The present invention relates to compounds of the formula (1), to the use thereof in electronic devices, and to electronic devices, particularly organic electroluminescence devices, comprising said compounds according to the invention, particularly as blue emitting material in an emitting layer.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: September 11, 2018
    Assignee: Merck Patent GmbH
    Inventors: Arne Buesing, Holger Heil, Philipp Stoessel
  • Patent number: 10072209
    Abstract: The invention relates to liquid-crystalline media which can be used, in particular, for electro-optical displays having active-matrix addressing based on the ECB effect and for IPS (in-plane switching) displays or FFS (fringe field switching) displays.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: September 11, 2018
    Assignee: Merck Patent GmbH
    Inventors: Melanie Klasen-Memmer, Marcus Reuter, Rocco Fortte, Detlef Pauluth, Matthias Bremer, Helmut Haensel, Harald Hirschmann
  • Patent number: 10071037
    Abstract: The present invention relates to the use of at least one cyclohexanol derivative of the formula (I) and/or (II) as antimicrobial active compound or as anti-acne, antidandruff, antiperspirant or deodorant active compound, to preparations comprising these compounds, and to specific cyclohexanol derivatives and to a process for the preparation thereof.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: September 11, 2018
    Assignee: MERCK PATENT GMBH
    Inventors: Thomas Rudolph, Tatjana Mueller
  • Publication number: 20180250233
    Abstract: The present invention relates to formulations having extended release of active ingredient, comprising an active ingredient from BCS Class I having high solubility and high permeability in a polyvinyl alcohol-containing matrix, from which the active ingredient is released at a controlled rate over a therapeutically relevant time period independently of the composition of the release medium.
    Type: Application
    Filed: August 25, 2016
    Publication date: September 6, 2018
    Applicant: MERCK PATENT GMBH
    Inventors: Finn BAUER, Thorsten WEDEL, Gudrun BIRK, Roberto OGNIBENE, Dieter LUBDA, Guenter MODDELMOG
  • Publication number: 20180251428
    Abstract: The present invention provides methods of preparing Praziquantel, in particular (R)-Praziquantel and analogues thereof in a stereoselective manner. One method involves asymmetric hydrogenation of the following intermediate compound and subsequent cyclization.
    Type: Application
    Filed: August 10, 2016
    Publication date: September 6, 2018
    Applicant: Merck Patent GmbH
    Inventors: Luc EBERHARDT, Andreas WAECHTLER, David MAILLARD, Stefan LEHMANN