Patents Assigned to Merck Patents GmbH
  • Beta-Hydroxyketones as topical active ingredients for the prevention or treatment of photodermatoses
    Publication number: 20180353442
    Abstract: The present invention relates to specific ?-hydroxyketones of the formula (I) for use in the prevention and/or treatment of photodermatoses and to the use of specific ?-hydroxyketones of the formula (I) as active ingredient in typical compositions for the prevention and/or non-therapeutic treatment of photodermatoses, in particular of polymorphic light eruption.
    Type: Application
    Filed: November 2, 2016
    Publication date: December 13, 2018
    Applicant: Merck Patent GmbH
    Inventors: Christophe CAROLA, Lilia HEIDER, Marina LEFORT, Hansjuergen DRILLER
  • CHEMICALLY DEFINED MEDIA FOR THE GROWTH OR DETECTION OF MICROORGANISMS
    Publication number: 20180355304
    Abstract: The present invention relates to chemically defined culture medium comprising at least one osmoprotectant compound and at least one fatty acid for the detection of a broad range of microorganisms.
    Type: Application
    Filed: November 8, 2016
    Publication date: December 13, 2018
    Applicants: Merck Patent GmbH, Universite de Strasbourg, Centre National de la Recherche Scientifique
    Inventors: Renaud CHOLLET, Antoine GILLMANN, Didier LIEVREMONT, Marie-Claire LETT
  • Liquid crystalline medium
    Patent number: 10150917
    Abstract: The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (??), which is distinguished by the fact that it has a value for the ratio ?1/?n2 in the range 6-45 with a clearing point of >60° C. and a ?? of ??2.3. Media of this type are particularly suitable for electro-optical displays having active-matrix addressing based on the ECB, PA LCD, FFS or IPS effect.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: December 11, 2018
    Assignee: MERCK PATENT GMBH
    Inventors: Melanie Klasen-Memmer, Sabine Schoen
  • A METHOD FOR EARLY DETECTION AND IDENTIFICATION OF MICROBIAL-COLONIES, APPARATUS FOR PERFORMING THE METHOD AND COMPUTER PROGRAM
    Publication number: 20180349671
    Abstract: The present invention is directed to a method for detection of microbial colonies on a surface, comprising the steps of obtaining one or a plurality of digital images I0, I1, I2, I3, I4 of the surface, said digital images I0, I1, I2, I3, I4 being represented by at least two-dimensional matrices of pixel values, calculating a statistical noise distribution based on at least one of the digital images I0, applying the statistical noise distribution calculated in the calculation step to the one or the plurality of digital images I0, I1, I2, I3, I4, and detecting an object of interest as a candidate for a microbial colony based on deviation of pixel values from the noise distribution.
    Type: Application
    Filed: August 17, 2016
    Publication date: December 6, 2018
    Applicants: MERCK PATENT GMBH, UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Marine BOUTHILLON, Luc FELDEN, Ola AHMAD, Christophe COLLET
  • OPPOSITE PH-SALT GRADIENTS FOR IMPROVED PROTEIN SEPARATIONS
    Publication number: 20180346510
    Abstract: The present invention relates to a method for an improved preparative separation of proteins, particularly monoclonal antibodies (mAB) from its associated charge variants (e. g. acidic and basic monomers), glycosylation variants, and/or soluble size variants (e. g. aggregates, monomers, ? fragments, ¾ fragments, antigen binding fragments (Fab) and crystallisable fragments (Fc).
    Type: Application
    Filed: October 28, 2016
    Publication date: December 6, 2018
    Applicant: MERCK PATENT GMBH
    Inventor: Matthias JOEHNCK
  • MONOLITHIC SORBENTS HAVING A METAL CLADDING
    Publication number: 20180348174
    Abstract: The invention relates to monolithic sorbents which are clad with tubes made of metal. The metal cladding can be applied directly to the monolithic sorbents by cold forming. This enables very mechanically stable cladding of the monolithic sorbents with minimal dead space.
    Type: Application
    Filed: October 28, 2016
    Publication date: December 6, 2018
    Applicant: Merck Patent GmbH
    Inventors: Karin CABRERA, Klaus KREHER, Gisela JUNG
  • Liquid crystalline medium
    Patent number: 10144870
    Abstract: The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (??), which is distinguished by the fact that it has a value for the ratio ?1/?n2 in the range 6-45 with a clearing point of >60° C. and a ?? of ??2.3. Media of this type are particularly suitable for electro-optical displays having active-matrix addressing based on the ECB, PA LCD, FFS or IPS effect.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: December 4, 2018
    Assignee: Merck Patent GmbH
    Inventors: Melanie Klasen-Memmer, Sabine Schoen
  • LIQUID CRYSTAL MEDIUM
    Publication number: 20180340121
    Abstract: The invention relates to a liquid-crystalline medium based on a mixture of polar compounds having positive dielectric anisotropy, characterised in that it comprises one or more compounds of the formula I in a total concentration of ?40%, in which the parameters have the meanings indicated in claim 1, and to the use of the liquid-crystalline medium for electro-optical purposes, in particular in liquid-crystal light valves for lighting devices for motor vehicles, and to liquid-crystal light valves which comprise this medium and lighting devices for motor vehicles which contain such liquid-crystal light valves.
    Type: Application
    Filed: October 5, 2016
    Publication date: November 29, 2018
    Applicant: MERCK PATENT GMBH
    Inventors: Michael WITTEK, Dagmar KLASS
  • Method of producing secretable antibodies by expression in saccharomyces cerevisiae
    Patent number: 10138477
    Abstract: The invention relates to a method for the production and non-covalent surface display of antibodies and derived fragments as well as molecule libraries based thereon on the surface of S. cerevisiae cells. The non-covalent manner of the surface display renders possible the selection of specific variants by means of high throughput screening and the subsequent switchable secretion of the selected binding molecule into the culture supernatant for biochemical characterization.
    Type: Grant
    Filed: December 11, 2013
    Date of Patent: November 27, 2018
    Assignee: MERCK PATENT GmbH
    Inventors: Ralph Guenther, Bjoern Hock, Stefan Becker, Laura Rhiel
  • Sample preparation device
    Patent number: 10139322
    Abstract: A sample preparation device, preferably for sterility testing, comprising a manifold including one or more receptacles for filtration units and at least one inlet and/or outlet port. The receptacle(s) is/are respectively provided with one or more connectors for establishing a fluid connection with mating ports of the filtration units and media containers/vials upon insertion of the same into the respective receptacles. The connectors are in fluid communication with the inlet and outlet port(s) via channels defined in the manifold to allow a desired fluid transfer through the manifold.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: November 27, 2018
    Assignee: MERCK PATENT GMBH
    Inventors: Stephane Olivier, Pierre Guedon, Florian Allard
  • Compounds for electronic devices
    Patent number: 10141518
    Abstract: The present invention relates to a compound of the formula (I), to the use of this compound in an electronic device, and to an electronic device comprising one or more compounds of the formula (I). The invention furthermore relates to the preparation of the compound of the formula (I) and to a formulation comprising one or more compounds of the formula (I).
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: November 27, 2018
    Assignee: Merck Patent GmbH
    Inventors: Philipp Stoessel, Arne Buesing, Frank Voges, Christof Pflumm, Amir Parham, Thomas Eberle, Teresa Mujica-Fernaud
  • Polymerisable mesogenic compound, liquid crystal medium and liquid crystal display
    Patent number: 10138420
    Abstract: The present invention relates to liquid crystal media comprising polymerizable mesogenic compounds with a bent shape, and to electro-optical displays comprising these media as light modulation media. In particular the electro-optical displays according to the present invention are displays, which are operated at a temperature, at which the liquid crystal modulation media are in an optically isotropic phase, preferably in a blue phase.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: November 27, 2018
    Assignee: Merck Patent GmbH
    Inventors: Michael Wittek, Norihiko Tanaka, Kevin Adlem, Matthias Bremer, David Wilkes, Ming-Chou Wu
  • Imidazole compounds as modulators of FSHR and uses thereof
    Patent number: 10138233
    Abstract: The present invention relates to imidazole compounds, and pharmaceutically acceptable compositions thereof, useful as positive allosteric modulators of follicle stimulating hormone receptor (FSHR).
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: November 27, 2018
    Assignee: Merck Patent GmbH
    Inventors: Henry Yu, Thomas E. Richardson, Marianne Donnelly, Ngan Nguyen, Xuliang Jiang
  • Layer arrangement for the regulation of light transmission
    Patent number: 10139658
    Abstract: A layer arrangement (1) which changes the transmission of incident light depending on its temperature, where the layer arrangement (1) has a first polarization layer (5a), a switching layer (2) which influences the polarization properties of light depending on the temperature, and a second polarization layer (5b), whereby both the first polarization layer (5a) and the second polarization layer (5b) are arranged to affect polarization both in the VIS region and in the NIR region.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: November 27, 2018
    Assignee: MERCK PATENT GMBH
    Inventors: Michael Junge, Andreas Beyer
  • DEVICE FOR REGULATING THE PASSAGE OF ENERGY
    Publication number: 20180335654
    Abstract: The present application relates to novel compounds and to devices which contain these compounds. The application also relates to a device for regulating the passage of energy from an outside space into an inside space, to a window containing the said device, and to uses of the said devices and compounds.
    Type: Application
    Filed: November 11, 2015
    Publication date: November 22, 2018
    Applicant: Merck Patent GmbH
    Inventors: Peer KIRSCH, Susann BECK, Michael JUNGE, Andreas BEYER, Ursula PATWAL
  • Enhancement of penetration and action
    Patent number: 10130827
    Abstract: The present invention relates, inter alia, to dermal systems comprising at least one light source and at least one pharmaceutically and/or cosmetically active ingredient. The dermal systems can be employed in order to enhance the penetration and action of the pharmaceutically and/or cosmetically active ingredient.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: November 20, 2018
    Assignee: Merck Patent GmBh
    Inventors: Herwig Buchholz, Ewald Aydt, Junyou Pan
  • Liquid-crystalline medium
    Patent number: 10131841
    Abstract: The invention relates to the compounds of the formula I and to a liquid-crystalline medium based on a mixture of polar compounds which contains at least one compound of the formula I in which R1, ring A1, L1, L2, L3, L4, L5, L6, L7, L8, Z1 and m have the meanings indicated in claim 1 and to the use of the LC mixtures in electro-optical displays, especially for the self-aligning VA mode.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: November 20, 2018
    Assignee: Merck Patent GmbH
    Inventors: Graziano Archetti, Izumi Saito, Rocco Fortte, Timo Uebel
  • Materials for electronic devices
    Patent number: 10135003
    Abstract: The present invention relates to an electronic device comprising anode, cathode and at least one organic layer which comprises a compound of the formula (I) to (IV). The invention furthermore encompasses the use of compounds of the formula (I) to (IV) in an electronic device and to a compound of the formula (Ic) to (IVc).
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: November 20, 2018
    Assignee: Merck Patent GmbH
    Inventors: Philipp Stoessel, Arne Buesing, Dominik Joosten
  • Doping media for the local doping of silicon wafers
    Patent number: 10134942
    Abstract: The present invention relates to a novel process for the preparation of printable, high-viscosity oxide media, and to the use thereof in the production of solar cells.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: November 20, 2018
    Assignee: MERCK PATENT GMBH
    Inventors: Ingo Koehler, Oliver Doll, Sebastian Barth
  • Rotary printing method
    Patent number: 10131168
    Abstract: The present invention relates to a rotary printing process for the application of functional coatings to a print substrate, to a coated print substrate produced by the said process, and to the use thereof, in particular in the packaging sector.
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: November 20, 2018
    Assignee: MERCK PATENT GMBH
    Inventors: Andreas Becker, Thomas Rathschlag, Johannes Tasch