Abstract: The present invention relates to iridium complexes suitable for use in organic electroluminescent devices, especially as emitters.

Abstract: An implant excision aid comprising a first plate comprising an external surface, an internal surface, a top portion, a bottom portion, a right side and a left side, wherein the bottom portion of the first plate is in communication with the patient's skin during use; a second plate comprising an external surface and an internal surface, a top portion, a bottom portion, a right side and a left side, wherein the bottom portion of the second plate is in communication with the patient's skin during use, wherein at least a portion of the bottom portion of the first or second plate or the internal surface of the first plate or second plate comprises a polymer or a metal, wherein the polymer or the metal generates enough friction so that the portion of the bottom of the first or second plate or the internal surface of the first plate or second plate is capable of moving the patient's skin during use; and a hinge wherein the hinge connects the top of the first plate to the top of the second plate.

Abstract: The present invention relates to a method for preparing an optoelectronic device comprising a crosslinked polymer material which is prepared from a crosslinkable polymer formulation comprising a polymer with a silazane repeating unit M1 and a Lewis acid curing catalyst. There is further provided a crosslinkable polymer formulation comprising a siloxazane polymer which is particularly suitable for the preparation of technical coatings on articles.

Abstract: The present invention relates to a method for preparing a nanosized light emitting semiconductor material, a nanosized light emitting semiconductor material, an optical medium comprising a nanosized light emitting semiconductor material, and an optical device comprising an optical medium.

Abstract: Liquid crystal (LC) media comprising polymerisable compounds as further specified in the description and claims and a self-alignment additive for vertical alignment. The media are adapted for use in LC displays, especially in LC displays of the polymer-sustained alignment type.

Abstract: Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.

Abstract: The present invention relates to compounds according to Formula I and pharmaceutically acceptable salts thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or conditions.

Abstract: The present invention presents a switching layer S for use in a switching element which has forwards-scattering properties in at least one switching state. Furthermore, a switching element which comprises the switching layer S and a window element which includes the switching element are presented.

Abstract: The present invention is directed to compounds of Formula I pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.

Abstract: Dielectrically positive liquid-crystalline media comprising one or more compounds of each of the formulae S1 and S2, and one or more compounds selected from the group of the compounds of the formulae II and III and/or IV and/or VIII, in which the parameters have the meanings indicated in the specification, and optionally one or more further dielectrically positive compounds and optionally one or more further dielectrically neutral compounds. Also, liquid-crystal displays, especially active-matrix displays and in particular TN, IPS and FFS displays, containing these media.

Abstract: The disclosure relates to HSV glycoprotein B and HSV glycoprotein C antigenic peptide constructs, HSV protein vaccines, and HSV DNA vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.

Abstract: The present invention is directed to pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

Abstract: The invention relates to a polymerisable LC material comprising one or more direactive mesogenic compounds selected from the group of compounds of formula I, and one or more monoreactive mesogenic compounds selected from the group of compounds of formula II, wherein the parameter A11, P11 to P21, R21, Sp11 to Sp21, X11 to X21, and Z11 to Z21 have one of the meanings as given in claim 1. Furthermore, the present invention relates also to a method for its preparation, a polymer film with improved thermal durability obtainable from the corresponding polymerisable LC material, to a method of preparation of such polymer film, and to the use of such polymer film and said polymerisable LC material for optical, electro-optical, decorative or security devices.

Abstract: The present invention relates to a formulation containing at least one organic functional material and at least two different solvents, a first organic solvent A and a second organic solvent B, wherein the first organic solvent A comprises a group, which is capable of receiving or giving a hydrogen bonding, and wherein the second organic solvent B has a boiling point in the range from 150 to 350° C. and the solubility of the at least one organic functional material in the second organic solvent is ?5 g/l.

Abstract: This disclosure relates to stable aqueous pharmaceutical formulations comprising a therapeutically effective amount of an incretin-insulin conjugate as well as methods of using the same, and aqueous pharmaceutical formulations containing an incretin-insulin conjugate which are stable and which provide a protracted pharmacodynamics profile, which include L-arginine HCl and phenol (or m-cresol) as stabilizing agents.

Abstract: The present invention provides, in part, an antibody display system that simultaneously uses a secretion and a display mode. Embodiments of the invention provide a system in which a bait complexed with a monovalent antibody fragment can be captured prior to secretion in a host cell by virtue of surface displaying an antibody light chain and utilizing the covalent interaction of this light chain with the heavy chain of an antibody molecule that is co-expressed in the same host. Polypeptides, polynucleotides and host cells useful for making the antibody display system are also provided along with methods of using the system for identifying antibodies that bind specifically to an antigen of interest.

Abstract: A composition comprising (S)—N-(3-(6-isopropoxypyridin-3-yl)-1H-indazol-5-yl)-1-(2(4-(4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)-3,6-dihydropyridin-1(2H)-yl)-2-oxoethyl)-3-(methylthio)pyrrolidine-3-carboxamide and hypromellose acetate succinate for pharmaceutical preparations, especially capsule preparations.

Abstract: The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions:

Abstract: A method and device for the optical scanning of a chromatographic sample (3), where a sample plate (2) holding the sample (3) is illuminated with light from a first illumination device (13) and the light emitted by the sample plate (2) is detected by an optical detector device (15) which detects in cell form or area form, a second illumination device (14) is preferably firstly activated in a preparation step. The sample plate (2) is displaced in a first displacement direction relative to the detector device (15), illuminated by the first illumination device (13) and a first measurement image is recorded. The sample plate (2) is displaced in a second displacement direction relative to the detector device (15), illuminated by the second illumination device (14), and a second measurement image is recorded.

Abstract: The invention relates to compounds of the formula (1) which are suitable for use in electronic devices, in particular organic electroluminescent devices.