Patents Assigned to Montefiore Medical Center
  • Methods and devices for intraoperative viewing of patient 3D surface images
    Patent number: 11727649
    Abstract: Methods and devices are disclosed for intra-operative viewing of pre- and intra-operative 3D patient images.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: August 15, 2023
    Assignees: MONTEFIORE MEDICAL CENTER, ALBERT EINSTEIN COLLEGE OF MEDICINE, The New York City Health and Hospitals Corporation
    Inventors: Oren Mordechai Tepper, Jillian Schreiber, Cesar Colasante
  • MULTIFUNCTIONAL CYTOPROTECTANT FOR TREATMENT OF PATHOGENIC PROCESSES MEDIATED BY OXIDATIVE STRESS AND TOXIC ELECTROPHILES
    Publication number: 20230133011
    Abstract: Methods, filters and compositions are disclosed for treating toxicity due to oxidative stress and toxic electrophiles.
    Type: Application
    Filed: August 2, 2022
    Publication date: May 4, 2023
    Applicant: MONTEFIORE MEDICAL CENTER
    Inventors: Richard M. LOPACHIN, Terrence GAVIN, Brian GEOHAGEN
  • Sterilizable fiducial beacon strand for RF target tracking
    Patent number: 11612716
    Abstract: A sterilizable device comprising electromagnetic transponders separated from one another by a flexible spacer material enclosed within radiofrequency-transparent sterilizable tubing for target tracking during prostate treatments, and method of use thereof.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: March 28, 2023
    Assignee: MONTEFIORE MEDICAL CENTER
    Inventors: Lee Goddard, Madhur Garg, Wolfgang Tomé, Carlo Greco
  • Transfemoral transcaval liver access and devices
    Patent number: 11504100
    Abstract: Shaped liver biopsy sheaths and methods for transfemoral transcaval liver access are disclosed.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: November 22, 2022
    Assignee: Montefiore Medical Center
    Inventors: Jacob Cynamon, Deborah Eliana Cynamon, Yosef Golowa
  • PEPTIDES THAT BLOCK PRESENTATION OF ANTIGENIC ISLET PEPTIDES BY HLA-DQ8 AND METHODS FOR TREATING TYPE-1 DIABETES
    Publication number: 20220306722
    Abstract: The disclosure provides polypeptides that specifically bind to HLA-DQ8 for treating Type 1 Diabetes (TID) and methods using same for reducing autoimmune destruction of pancreatic islet beta cells. In particular, the present disclosure relates to peptides containing at least one D-amino acid that are capable of blocking the presentation of antigenic islet peptides (e.g., lnsB:9-23) by HLA-DQ8, and to their uses, especially as it relates to the prevention and/or treatment of TID.
    Type: Application
    Filed: August 4, 2020
    Publication date: September 29, 2022
    Applicants: Icahn School of Medicine at Mount Sinai, Montefiore Medical Center, Albert Einstein College of Medicine, Inc.
    Inventors: Yaron Tomer, Roman Osman, Angela Lombardi
  • Multifunctional cytoprotectant for treatment of pathogenic processes mediated by oxidative stress and toxic electrophiles
    Patent number: 11413255
    Abstract: Methods, filters and compositions are disclosed for treating toxicity due to oxidative stress and toxic electrophiles.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: August 16, 2022
    Assignee: Montefiore Medical Center
    Inventors: Richard M. LoPachin, Terrence Gavin, Brian Geohagen
  • Delivery of therapeutic agents by a collagen binding protein
    Patent number: 11279922
    Abstract: Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. In these methods, the therapeutic agent is not a PTH/PTHrP receptor agonist or antagonist, basic fibroblast growth factor (bFGF) or epidermal growth factor (EGF). The bacterial collagen-binding polypeptide segment delivers the agent to sites of partially untwisted or under-twisted collagen. Methods of treating collagenopathies using a composition including a collagen-binding polypeptide and a PTH/PTHrP receptor agonist are also provided. In addition, methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. Finally, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: March 22, 2022
    Assignees: The Board of Trustees of the University of Arkansas, The Kitasato Institute, Montefiore Medical Center, National University Corporation Kagawa University
    Inventors: Tulasi Ponnapakkam, Sagaya Theresa Leena Philominathan, Joshua Sakon, Ranjitha Katikaneni, Takaki Koide, Osamu Matsushita, Robert C. Gensure, Nozomu Nishi
  • NUCLEOPHILIC CHEMICALS USEFUL IN THE TREATMENT OF CISPLATIN-INDUCED SENSORY NEUROPATHY AND OTOTOXICITY
    Publication number: 20220016051
    Abstract: Methods and compositions are disclosed for reducing neuropathy or ototoxicity associated with chemotherapeutic agents by administering one or more enol compounds to a subject.
    Type: Application
    Filed: December 27, 2019
    Publication date: January 20, 2022
    Applicant: MONTEFIORE MEDICAL CENTER
    Inventors: Richard LOPACHIN, Brian C. GEOHEGAN
  • STERILIZABLE FIDUCIAL BEACON STRAND FOR RF TARGET TRACKING
    Publication number: 20210283370
    Abstract: A sterilizable device comprising electromagnetic transponders separated from one another by a flexible spacer material enclosed within radiofrequency-transparent sterilizable tubing for target tracking during prostate treatments, and method of use thereof.
    Type: Application
    Filed: January 22, 2018
    Publication date: September 16, 2021
    Applicant: MONTEFIORE MEDICAL CENTER
    Inventors: Lee Goddard, Madhur Garg, Wolfgang Tomé, Carlo Greco
  • Delivery of therapeutic agents by a collagen binding protein
    Patent number: 11001820
    Abstract: Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. In these methods, the therapeutic agent is not a PTH/PTHrP receptor agonist or antagonist, basic fibroblast growth factor (bFGF) or epidermal growth factor (EGF). The bacterial collagen-binding polypeptide segment delivers the agent to sites of partially untwisted or under-twisted collagen. Methods of treating collagenopathies using a composition including a collagen-binding polypeptide and a PTH/PTHrP receptor agonist are also provided. In addition, methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. Finally, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: May 11, 2021
    Assignees: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS, MONTEFIORE MEDICAL CENTER
    Inventors: Tulasi Ponnapakkam, Sagaya Theresa Leena Philominathan, Joshua Sakon, Ranjitha Katikaneni, Takaki Koide, Osamu Matsushita, Robert C. Gensure, Nozomu Nishi
  • Low intensity focused ultrasound for treating cancer and metastasis
    Patent number: 10974077
    Abstract: Systems and methods for treating cancer and for preventing metastasis using low intensity focused ultrasound in combination with an anti-cancer therapy are disclosed.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: April 13, 2021
    Assignees: MONTEFIORE MEDICAL CENTER, ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.
    Inventors: Chandan Guha, Stephen Barry, Fernando Macian
  • METHODS AND DEVICES FOR INTRAOPERATIVE VIEWING OF PATIENT 3D SURFACE IMAGES
    Publication number: 20210035370
    Abstract: Methods and devices are disclosed for intra-operative viewing of pre- and intra-operative 3D patient images.
    Type: Application
    Filed: October 2, 2020
    Publication date: February 4, 2021
    Applicants: MONTEFIORE MEDICAL CENTER, ALBERT EINSTEIN COLLEGE OF MEDICINE, The New York City of Health and Hospitals Corporation
    Inventors: Oren Mordechai TEPPER, Jillian SCHREIBER, Cesar COLASANTE
  • Intervention for tendinopathy
    Patent number: 10874748
    Abstract: Methods for treating tendinopathy and tendonitis and for preventing tendinopathy are disclosed.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: December 29, 2020
    Assignees: Albert Einstein College of Medicine, Icahn School of Medicine at Mount Sinai, Montefiore Medical Center
    Inventors: Hui B. Sun, Evan L. Flatow, Tony Wanich, Konrad Gruson, Nelly Andarawis-Puri
  • Methods and devices for intraoperative viewing of patient 3D surface images
    Patent number: 10810799
    Abstract: Methods and devices are disclosed for intra-operative viewing of pre- and intra-operative 3D patient images.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: October 20, 2020
    Assignees: Montefiore Medical Center, Albert Einstein College of Medicine
    Inventors: Oren Mordechai Tepper, Jillian Schreiber, Cesar Colasante
  • Methods and compositions for treating and preventing arthritis
    Patent number: 10772846
    Abstract: Methods and formulations are provided for treating or preventing arthritis, in particular osteoarthritis, where the formulation to be administered to a subject for treating or preventing arthritis comprises carvacrol, curcumin, epigallocatechin-3-gallate and oligomeric procyanidins. The invention provides methods of treating or preventing arthritis, such as osteoarthritis, in a subject in need thereof comprising administering to the subject a formulation or composition comprising carvacrol, curcumin, epigallocatechin-3-gallate and oligomeric procyanidins in an amount effective to treat or prevent arthritis.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: September 15, 2020
    Assignees: Montefiore Medical Center, Albert Einstein College of Medicine
    Inventors: Hui B. Sun, Daniel J. Leong, Neil J. Cobelli, David M. Hirsh, John A. Hardin, Karen E. Sperling, Sun Jin Kim, David C. Spray, Chandan Guha, Marwa Choudhury
  • TRANSFEMORAL TRANSCAVAL LIVER ACCESS AND DEVICES
    Publication number: 20200113553
    Abstract: Shaped liver biopsy sheaths and methods for transfemoral transcaval liver access are disclosed.
    Type: Application
    Filed: October 21, 2019
    Publication date: April 16, 2020
    Applicant: Montefiore Medical Center
    Inventors: Jacob Cynamon, Deborah Eliana Cynamon, Yosef Golowa
  • DELIVERY OF THERAPEUTIC AGENTS BY A COLLAGEN BINDING PROTEIN
    Publication number: 20190249163
    Abstract: Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. In these methods, the therapeutic agent is not a PTH/PTHrP receptor agonist or antagonist, basic fibroblast growth factor (bFGF) or epidermal growth factor (EGF). The bacterial collagen-binding polypeptide segment delivers the agent to sites of partially untwisted or under-twisted collagen. Methods of treating collagenopathies using a composition including a collagen-binding polypeptide and a PTH/PTHrP receptor agonist are also provided. In addition, methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. Finally, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
    Type: Application
    Filed: February 22, 2019
    Publication date: August 15, 2019
    Applicants: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSA S, The Kitasato Institute, MONTEFIORE MEDICAL CENTER, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERISTY
    Inventors: Tulasi Ponnapakkam, Sagaya Theresa Leena Philominathan, Joshua Sakon, Ranjitha Katikaneni, Takaki Koide, Osamu Matsushita, Robert C. Gensure, Nozomu Nishi
  • DEVICES AND METHODS FOR RESPIRATORY AIRWAYS BLEEDING MANAGEMENT AND TEMPORARY OCCLUSION OF AIRWAYS
    Publication number: 20190150963
    Abstract: Catheters and methods for controlling bleeding in airways and for occlusion of airways are provided that allow a bronchoscope to be withdrawn from the airway while an inflated balloon catheter remains in position in the airway, for example at a site of airway bleeding.
    Type: Application
    Filed: May 15, 2017
    Publication date: May 23, 2019
    Applicant: MONTEFIORE MEDICAL CENTER
    Inventor: Ali Sadoughi
  • Delivery of therapeutic agents by a collagen binding protein
    Patent number: 10213488
    Abstract: Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: February 26, 2019
    Assignees: The Board of Trustees of the University of Arkansas, The Kitasato Institute, Montefiore Medical Center
    Inventors: Tulasi Ponnapakkam, Sagaya Theresa Leena Philominathan, Joshua Sakon, Ranjitha Katikaneni, Takaki Koide, Osamu Matsushita, Robert C. Gensure
  • Sternal osteotomy guide and sternal fixation system
    Patent number: 10179011
    Abstract: Systems and methods are described for a sternal osteotomy guide and sternal fixation system.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: January 15, 2019
    Assignee: Montefiore Medical Center
    Inventors: Evan S. Garfein, David S. Geller, Katherine A. Weimer