Abstract: The present invention is based on the finding that administration of polypeptides comprising at least one Immunoglobulin single variable domains against vWF to human TTP patients provides a significant decrease in the time to response. The invention provides a polypeptide comprising at least one immunoglobulin single variable domain (ISVD) against von Willebrand Factor (vWF) for use in treating a vWF-related disease in a human in need thereof. The invention further relates to dosage unit forms, kits and medical uses for treating TTP.

Abstract: The invention relates to a system comprising a mobile device (1), a device (13b) for transmitting information, a device (15) hosting a device registry (14) and a wireless device (3a). The mobile device (1) comprises a receiver, a transmitter, storage means and a processor.

Abstract: The present disclosure relates to fixation devices. Certain embodiments provide a fixation device for insertion into bone. The fixation device includes a body comprising threads along an outer surface of the body. The fixation device includes one or more blades movably coupled to the body. The one or more blades are configured to move between at least a first position and a second position. In the first position, the one or more blades are retracted into the body. In the second position, the one or more blades are deployed out of the body for insertion into the bone.

Abstract: Methods and systems are described for reducing particles in the vicinity of an electrostatic chuck (300) in which a cleaning reticle or substrate (320) is secured to the chuck, the cleaning reticle or substrate having surfaces partially devoid of conductive material so that an electric field from the chuck can pass through to a volume adjacent the substrate to draw particles (360) in the volume to the surface of the substrate. Voltage supplied to the chuck may have an alternating polarity to enhance the attraction of particles to the surface.

Abstract: Various methods, apparatuses/systems, and media for providing IaC templates in a cloud environment are provided. A processor creates a plurality of IaC templates. Each of the plurality of IaC templates includes instructions to build at least a portion of an infrastructure. The plurality of IaC templates is stored in a central repository. The processor collects one or more of the plurality of the created IaC templates from the central repository in order to build a desired infrastructure package. The processor also executes at least one of updating, removing, upgrading, downgrading, and verifying the infrastructure package in the central repository. Each of the plurality of IaC templates also includes metadata identifying at least one of a package, installation instructions of the package, at least one dependency of the package, a version of the package, and a size of the package.

Abstract: An apparatus and a method are provided for an air filter cleaning wand for flushing contaminants from an intake air filter of an automobile engine. The air filter cleaning wand comprises a proximal flange, a conduit, and a distal end portion. The proximal flange is configured to receive a nozzle of a water hose. An interior of the conduit is in fluid communication with the proximal flange. The distal end portion comprises a plurality of longitudinally aligned vents in fluid communication with the interior of the conduit. Upon passing water through the water hose and into the conduit, pressurized water streams exit the vents along the distal end portion so as to flush contaminants from the air filter. The air filter cleaning wand advantageously is comprised of a material which is sufficiently durable and temperature resistant to retain its configuration during operation when coupled to pressurized water sources.

Abstract: Apparatus for determining a spatial property in a 3D-space, wherein the apparatus comprises a physical pointer, a camera and a position and orientation measurement system, wherein a first object in the 3D-space comprises a pattern on it, wherein the physical pointer is configured to contact a surface area of a second object in the 3D-space, wherein the camera is configured to capture, at a position of the camera with respect to the first object, image data comprising an image of the pattern; wherein the position and orientation measurement system is configured to determine a heading, position, verticality, attitude, and/or inclination of the camera based on the image of the pattern, and determine, based on the determined heading, position, verticality, attitude, and/or inclination of the camera and a relative position of the physical pointer with respect to the camera, the spatial property of the surface area by the physical pointer.

Abstract: A ball lift sleeve and retrieval tool comprising a sleeve for disposing in tubing of a well, the sleeve defining a first passage from a first proximal end to a first distal end, and a retrieval tool for disposing in the tubing of the well, the retrieval tool being separately moveable in the tubing between mated and unmated conditions with respect to the sleeve, the retrieval tool at least partially mating with the first distal end of the sleeve when in the mated condition and at least partially closing fluid communication through the passage of the sleeve when mated therewith.

Abstract: Systems and methods for generating a data model from protocol buffer compiler generated Java classes are provided. The methods include obtaining a protocol buffers schema; using the obtained protocol buffers schema to generate a plurality of Java classes; determining, from the plurality of Java classes, a plurality of attributes; determining, for each respective attribute, a corresponding attribute type; and using each respective attribute and each corresponding attribute type to extract model information to be included in the data model. The extracted model information may be adjusted based on whether the information matches with an expectation regarding the model information.

Abstract: Techniques are disclosed for measuring bioimpedance of a biological object with an alternating current (AC) source, a pair of electrodes, a reference load, a switching arrangement switchable between a first switch condition and a second switch condition, and measuring electronics. When the switching arrangement is in the first switch condition, the AC source is applied across the reference load and a group delay of the measuring electronics is determined. When the switching arrangement is in the second switch condition, and the pair of electrodes is in contact with the biological object, a voltage waveform based on the AC source being applied across the pair of electrodes is measured and a calibrated voltage waveform is determined, the calibrated voltage waveform being corrected for the group delay. The bioimpedance value of the biological object is determined based on the calibrated voltage waveform.

Abstract: A pervasive user experience capable of integrating robo-advising with human advising is discussed. Conversations and other inputs may be actively captured to identify issues with which the system may be able to assist. Inputs from multiple conversations separated in time may be correlated to identify relevant needs and goals. Recommendations and strategies may be developed and presented to the customer. When it is determined that human advising is appropriate for one or more issues, the customer may be connected to an advisor for assistance with particular issues. Transitions may be facilitated to allow customers to more efficiently return to robo-advising until human advising is again deemed appropriate.

Abstract: A circuit has a first window comparator determining whether a signal at a first input has a voltage higher than a first threshold but lower than a second threshold, and a second window comparator determining whether a signal at a second input has a voltage higher than the first threshold but lower than the second threshold. A logic circuit generates pulses in response to either the first window comparator determining that the signal at the first differential input has a voltage higher than the first threshold but lower than the second threshold or the second window comparator determining that the signal at the second input has a voltage higher than the first threshold but lower than the second threshold. A filter circuit receives the pulses from the logic circuit and generates a flag indicating that the signal is invalid, based upon pulses received from the logic circuit.

Abstract: Systems and methods related facilitating default sharing between frequently used line of business products according to one or more example embodiments are shown. Such systems and methods make use of sharing of information between the line of business products. In some embodiments, this sharing of the data between line of business products facilitates a universal portal that may be personalized and/or customized in function and appearance. In some embodiments, the universal portal is an application on a user device that, at least, provides access to other applications running on the user device in a consolidated manner as well as additional functions present in the universal portal itself. In some embodiments, visual aspects of the presentation of applications and functionality are changed in the universal portal based on information that has been shared between different line of business products.

Abstract: Financial communications can be managed to account for customer incapacity. A determination can be made that a primary responder is unable to receive or respond to a financial communication due to incapacity. The determination can be made based on a change in account activity or a lack of responsiveness. Based on a type of the financial communication, a secondary responder can be identified, and the financial communication of the primary responder is sent to the secondary responder.

Abstract: Examples of a system and method may generally provide a graphical user interface for qualitative risk profile determination. A method may include providing a graphical user interface including a plurality of related qualitative graphs. The method may include receiving a selection from a user of one of the plurality of related qualitative graph and automatically determining a risk profile for the user. The risk profile may be provided on the graphical user interface.

Abstract: Systems and methods for enhanced organizational transparency using a linked activity chain in a ledger are disclosed. In one embodiment, a method may include (1) a back end for an organization comprising at least one computer processor receiving a first communication from a first entity comprising a first customer interaction with the first entity; (2) the back end writing the first communication to a ledger for the organization as a first block in a linked activity chain; (3) the back end receiving a second communication from a second entity comprising a second customer second activity with the second entity; (4) the back end writing the second communication to the ledger for the organization as a second block in the linked activity chain; (5) the back end calculating a summary score for the customer based on the blocks in the linked activity chain.

Abstract: Systems and methods for using an information wallet system to deliver a gift and receive, redeem, or re-gift the gift are disclosed. The information wallet system's storage is securely maintained by a financial institution computing system (i.e. a bank) and receives and holds purchase transaction information. Purchase information transaction may be received from a user computing device or an entity computing system, such as a merchant computing system. In one embodiment, a user may purchase a gift through an online website or at a brick and mortar location and direct the gift to be deposited into the information wallet storage of a recipient. A recipient may then continue to hold the gift, redeem the gift, or re-gift the gift to another party.

Abstract: An image processing system and related method. The system comprises an input interface (IN) for receiving dark-field image data obtained from imaging of an object (OB) with an X-ray imaging apparatus (XI). A corrector module (CM) of the system (IPS) is configured to perform a correction operation to correct said dark-field image data for Compton scatter to obtain Compton-Scatter corrected image data. The so Compton scatter corrected image data is output by an output interface (OUT) of the system.

Abstract: Systems and methods for identifying financial transaction opportunities for individualized offers are disclosed. In one embodiment a method for offering rewards to a customer of a financial institution may include (1) a server comprising at least one computer processor identifying a customer spending opportunity for a customer to use a financial instrument issued by a financial institution to conduct a transaction involving the customer spending opportunity; (2) the server determining an incentive to offer the customer for using the financial instrument issued by the financial institution to conduct the transaction involving the customer spending opportunity; and (3) the server communicating the incentive to an electronic device associated with the customer.

Abstract: The present invention relates to an inductor (10) for high frequency and high power applications. The inductor (10) comprises at least one wire conductor (20), and a coil zone (30). Windings of the at least one wire conductor comprises the at least one wire conductor being wound around the coil zone to form a substantially torus shape centred around an axis extending in an axial direction of the torus shape. At an outer extent of the coil zone, outer windings of the at least one wire conductor are substantially at a first radial distance from the axis. At an inner extent of the coil zone, inner windings of the at least one wire conductor are substantially at a second radial distance from the axis and substantially at a third radial distance from the axis respectively. When an inner winding of the at least one conductor is at the second radial distance the next inner winding of the at least one conductor is at the third radial distance.