Abstract: According to an embodiment, an integrated circuit includes a complementary metal-oxide-semiconductor (CMOS) logic gate, a series p-channel transistor, and a shunt n-channel transistor. The CMOS logic gate includes a first p-channel transistor and a first n-channel transistor. The first p-channel transistor and the series p-channel transistor are configurable to be body biased. The series p-channel transistor is coupled between an output terminal of the CMOS logic gate and the first p-channel transistor. The shunt n-channel transistor is coupled between the output terminal of the CMOS logic gate and the reference ground. A gate terminal of the series p-channel transistor is coupled to a gate terminal of the shunt n-channel transistor and configured to receive a sleep signal during a low-power operating mode of the CMOS logic gate.

Abstract: Systems and methods provide a first deployment criterion for deploying modified decision engines. A first existing decision engine is accessed, as well as a first modified decision engine that includes rule data generated by an artificial intelligence model based on the first existing decision engine. A first difference between a first output and a first modified output is determined, where the first output is generated by the first existing decision engine and the first modified output is generated by the first modified decision engine. A first selected decision engine is deployed to process subsequent data items to produce subsequent outputs, based on whether the first difference satisfies first deployment criterion. When metric generated based on the subsequent outputs satisfies a criterion modification condition, the artificial intelligence model is used to generate a second deployment criterion, wherein a second selected rule-based decision engine is deployed based on the second deployment criterion.

Abstract: An electric toothbrush (10) and method of operating an electric toothbrush. The electric toothbrush includes a handle portion (14) having a shaft (38) configured to receive a brushing load from a bristled end (18) of a brush head (12). A sensor assembly (30) is configured to determine a deflection proportional to the brushing load with respect to a first direction (24) associated with the brushing load. The sensor assembly includes an air gap (32) and is configured to determine the deflection based on changes in the air gap. A mounting bracket (50) is connected between opposite sides of the air gap, the mounting bracket having a first bending stiffness with respect to the first direction, and a second bending stiffness with respect to a second direction (28) generally opposite to the first direction. The first bending stiffness is greater than the second bending stiffness.

Abstract: VH domain, in which: (i) the amino acid residue at position 1 12 is one of K or Q; and/or (ii) the amino acid residue at position 89 is T; and/or (iii) the amino acid residue at position 89 is L and the amino acid residue at position 1 10 is one of K or Q; and (iv) in each of cases (i) to (hi), the amino acid at position 1 1 is preferably V; and in which said VH domain contains a C-terminal extension (X)n, in which n is 1 to 10, preferably 1 to 5, such as 1, 2, 3, 4 or 5 (and preferably 1 or 2, such as 1); and each X is an (preferably naturally occurring) amino acid residue that is independently chosen, and preferably independently chosen from the group consisting of alanine (A), glycine (G), valine (V), leucine (L) or isoleucine (I).

Abstract: There is provided an apparatus (12) for use with a wearable cuff (14) in measuring blood pressure. The cuff (14) is inflatable to pressurize a measurement site (20) of a subject (18). The apparatus (12) is configured to estimate a size of the cuff (14) during a current inflation of the cuff (14) and compare the estimated size of the cuff (14) to a previous size of the cuff (14) estimated during an inflation of the cuff (14) that immediately preceded the current inflation of the cuff (14). The apparatus (12) is also configured to, if the estimated size of the cuff (14) differs from the previous size of the cuff (14) by more than a predefined amount, change a pressure up to which the cuff (14) is inflated before deflation of the cuff (14) starts.

Abstract: Systems, apparatuses, methods, and computer program products are disclosed for facilitating on-demand delivery of unknown qubits. An example method includes determining a first quantum basis pattern. The example method further includes encoding, by encoding circuitry, a set of bits utilizing the first quantum basis pattern to generate a set of qubits and transmitting, by quantum communications circuitry, the set of qubits over a quantum line, for example, a polarization maintaining optical fiber, to a remote device, wherein the set of qubits is configured for measurement by an independently determined, second quantum basis pattern, resulting in a second set of bits different than the first set of bits.

Abstract: Disclosed herein is a radiological instrument (100, 200, 300, 400, 600, 700, 800) comprising at least one pulse shaper circuit (102) configured for a direct conversion radiation detector (108). The at least one pulse shaper circuit comprises an amplifier (110). The pulse shaper further comprises a feedback circuit (118) connected in parallel with the amplifier; a first switching unit (120) connected in series with the feedback circuit; a second switching unit (122) connected in parallel with the amplifier; a discriminator circuit (124) that provides a discriminator signal (128) when the output exceeds a controllable signal threshold; and a control unit (124) for controlling the first switching unit and the second switching unit, wherein the control unit controls the second switching unit such that a substantial part of the signal is integrated, when the second switching unit is closed.

Abstract: A tensioner assembly for tensioning a belt including a moveable arm, a first tensioner pulley mounted to the moveable arm, and a second tensioner pulley mounted to the moveable arm. In a first position of the moveable arm corresponding to a forward drive configuration, the first tensioner pulley is positioned in contact with the belt while the second tensioner pulley is spaced apart from the belt. In a second position of the moveable arm corresponding to a reverse drive configuration, the second tensioner pulley is positioned in contact with the belt while the first tensioner pulley is spaced apart from the belt.

Abstract: A computer-implemented method includes receiving a first transaction request including a first transaction amount, determining that the first transaction amount would cause a violation of a daily spending limit, determining to apply an adaptive daily spending limit (ADSL) override, generating an approval message indicating that the first transaction request is approved based on the application of the ADSL override, transmitting the approval message to the ATM, and dispensing the first transaction amount in a currency by the ATM.

Abstract: The model generation platform enables generation of machine learning models based on modular storage of user-specified training data. The platform can obtain a dataset from a different heterogenous source (e.g., a structured database, an unstructured database, a semi-structured file system, manual upload of a comma-separated value file, a spreadsheet, and/or big data) through an associated application programming interface and store this data in a first storage medium. The model generation platform can obtain an indication of a portion of the dataset from a user via a user interface and determine a second storage medium for this portion of the dataset based on an associated estimated performance metric. In response to a request for generation of a machine learning model, the model generation platform can generate a machine learning model using training data comprising a subset of the portion of the dataset.

Abstract: The present invention provides a novel compound having a protein kinase inhibitory activity, stereoisomers thereof or pharmaceutically acceptable salts thereof. The compound according to the present invention, stereoisomers thereof or pharmaceutically acceptable salts thereof are effective in preventing or treating protein kinase-related diseases such as cancers, autoimmune diseases, neurological diseases, metabolic diseases, infections or the like by showing a protein kinase inhibitory activity.

Abstract: An ultrasound transducer array includes an array of elongate support members that are displaceable and/or deformable relative to each other in the elongation direction of the elongate support members, each elongate support member having a patient facing surface carrying an ultrasound transducer tile; and multiple sensors, each adapted to detect the relative displacement and/or deformation of one of the elongate support members. The ultrasound transducer array may be included in an ultrasound system.

Abstract: A medical system (100, 500) includes: a radiotherapy system (102) configured for controllably irradiating a target volume (114) within an irradiation zone (112); a subject support (120) configured for supporting at least a ventral region (124) of a subject (122) within the irradiation zone; a breath monitor system (132, 132?) configured for providing a motion signal (154, 158) descriptive of subject breathing motion; and a subject display (130, 130?) configured for displaying a breathing phase indicator (160, 160?) to the subject when supported by the subject support. Execution of the machine executable instructions (150) causes a processor (142) to carry out certain functions of the medical system.

Abstract: A glass-ceramic article, includes at least one substrate, such as a plate, made of glass-ceramic, the substrate being coated in at least one zone with at least one layer including zirconium silicon nitride, SixZryNz, with an atomic ratio of Zr to the sum Si+Zr, y/(x+y), of 10% to 90%.

Abstract: An integrated circuit includes a substrate having a front face. A capacitive element includes, over a surface at the front face, a stack made of: a first conductive armature, a dielectric interface region over the first conductive armature, and a second conductive armature over the dielectric interface region. The first conductive armature includes a gate metal layer located over a layer of a material with a high dielectric constant.

Abstract: A system includes a tabletop display and a processing circuit including one or more processors coupled to a non-transitory computer-readable medium storing instructions that, when executed, cause the processing circuit to cause an image comprising first information and second information to be displayed on a tabletop display, receive a security trigger, and cause the first information to be obscured on the tabletop display based on receiving the security trigger.

Abstract: A microelectromechanical sensor assembly includes a semiconductor die having a scaled cavity. A microelectromechanical inertial sensor has a sensing mass. A piezoelectric vibration sensor has a piezoelectric membrane. The sensing mass and the piezoelectric membrane are stacked one on top of the other and housed in the sealed cavity.

Abstract: A MEMS sensor comprising a semiconductor body and a mass elastically coupled to the semiconductor body for oscillating with respect to the semiconductor body in a oscillation direction in response to a force acting on the mass in the oscillation direction, the force being caused by an acceleration applied to the MEMS sensor. The mass and the semiconductor body define at least one measurement structure with parallel-plate electrodes, which is configured to measure capacitively a position of the mass that is indicative of the acceleration applied to the MEMS sensor. The mass and the semiconductor body further define a calibration structure with comb-finger electrodes that is electrically controllable, in a calibration mode of the MEMS sensor, to bring about electrostatically a displacement of the mass with respect to the semiconductor body in the oscillation direction.

Abstract: The present disclosure relates to novel PD-1 binding domains that have a higher binding affinity for human PD-1 than a reference PD-1 binding domain. The PD-1 binding domains of the present disclosure further provide a comparable, or equal or higher, potency in blocking ligand binding to human PD-1 than a reference PD-1 antibody. The present disclosure further relates to binding moieties comprising such PD-1 binding domains. Also provided is a method for treating a disease, in particular a disease associated with a suppressed immune system, such as cancer, with a PD-1 binding domain or binding moiety of the present disclosure. The present disclosure further relates to nucleic acids encoding the heavy chain variable region of the PD-1 binding domains, and a vector and cell comprising such nucleic acid.

Abstract: A method and a system for training a neural language-based model for data annotation are disclosed. The method includes: receiving, via a communication interface, a set of data from a plurality of sources, each item of the set of data being associated with a pre-defined data class; generating at least one category vocabulary for the pre-defined data class; identifying at least one token in the set of data based on an analysis of the set of data, wherein the at least one token corresponds to a category indicator of the pre-defined data class; masking the at least one token; feeding the at least one masked token together with a corresponding contextual vector to the neural language-based model; and predicting, using the neural language-based model, a class of the at least one masked token using the corresponding contextual vector.