Patents Assigned to Nagasaki University
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Publication number: 20100137535Abstract: There are provided a composite particle comprising polystyrene and a filler, and having high levels of affinity between the filler and the polystyrene matrix, few or a small number of voids at the interface between the filler and the polystyrene matrix, and an excellent mechanical properties, and a method for preparing the same composite particle. The polystyrene-maleic anhydride/magnesium hydroxide composite particle is produced by bulk polymerization of a blend of a styrene monomer, a crosslinking agent, a polymerization initiator, maleic anhydride, and magnesium hydroxide which is coated with a surface-treatment agent in advance to impart hydrophobicity thereto, and subsequently suspension polymerization of a product obtained from the bulk polymerization.Type: ApplicationFiled: October 31, 2007Publication date: June 3, 2010Applicants: Yazaki Corporation, Nagasaki University, National University CorporationInventors: Shiyuuichi Kimura, Kiyoshi Yagi, Makoto Egashira
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Publication number: 20100135046Abstract: The first sampling measurement value compares whether to exceed a prescribed threshold and judges the control part at the sampling time. The control part compares whether the first sampling measurement value exceeds a prescribed threshold. When the actual measurement value doesn't exceed a prescribed threshold, the control part predict the first sampling value at the next sampling time. [1] When the first sampling the predicting value doesn't exceed the threshold value, the status of the switch is maintained, [2] When the first sampling the predicting value exceeds the threshold value, the time when the movement of the switch should be changed is calculated and the status of the switch is changed at time concerned.Type: ApplicationFiled: April 30, 2008Publication date: June 3, 2010Applicant: Nagasaki University, National University CorporatiInventor: Fujio Kurokawa
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Publication number: 20100105918Abstract: A novel luminescent metal complex comprises a composition of [(PtII)2(AuI)2(MI)2(L)8] where MI denotes AgI or CuI, and L denotes a structure represented by the formula (1)Type: ApplicationFiled: March 5, 2008Publication date: April 29, 2010Applicant: Nagasaki UniversityInventors: Keisuke Umakoshi, Keizo Saito, Masayoshi Onishi, Shoji Ishizaka, Noboru Kitamura
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Publication number: 20100010231Abstract: There is provided a novel luminescent metal complex. A metal complex having a composition of [(PtII)2(MI)2(X)2(L)4(LH)2], where MI denotes AgI, AuI or CuI, X denotes Cl, Br or I, L denotes a structure represented by the formula (1), and LH denotes a structure represented by the formula (2).Type: ApplicationFiled: November 1, 2007Publication date: January 14, 2010Applicant: Nagasaki UniversityInventors: Keisuke Umakoshi, Seiji Akatsu, Masayoshi Onishi, Shoji Ishizaka, Noboru Kitamura
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Publication number: 20100003191Abstract: The present invention provides a composition for diagnosing amyloid-related diseases, comprising a compound represented by general formula (I): wherein X represents O or the like; R1, R3, R4, R5, R6, R8 and R9 represent a hydrogen atom or the like; R2 represents a halogen atom or the like; and R7 represents a dimethylamino group or the like; or the compound labeled with a radionuclide, or a pharmaceutically acceptable salt of the compound or the labeled compound. The compound represented by general formula (I) has all of the following properties: high binding specificity to amyloid ? protein, high permeability through the blood-brain barrier, and rapid clearance from sites without senile plaques in the brain.Type: ApplicationFiled: October 26, 2007Publication date: January 7, 2010Applicant: NAGASAKI UNIVERSITYInventor: Masahiro Ono
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Publication number: 20090320658Abstract: The present invention provides cutting methods and cutting apparatus that can precisely cut workpieces in complicated shapes with high aspect ratios regardless of materials of the workpieces. The present invention is cutting methods and cutting apparatus using a wire saw wherein cutting processing is performed for a workpiece by extending a cutting wire on a cutting arm that rotates around a wire's center axis or a real cutting position relative to a fixed section and rotating the cutting arm such that a cutting direction of the wire matches a support direction of a total stiffness that supports the wire.Type: ApplicationFiled: June 27, 2007Publication date: December 31, 2009Applicant: Nagasaki UniversityInventors: Takanori Yazawa, Keiichi Ishikawa, Kou Mineta
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Publication number: 20090219055Abstract: The voltage deviation is converted into the time quantity with the first integration circuit for the voltage detection and the second integration circuit for the voltage detection. The current setting value and the current measurements are converted into the time quantity with the second integration circuit for the current control to which the first integration circuit for the current control from which the voltage value of the set current value corresponding is input and the voltage value of the value of the current of the inductor corresponding are input and it controls. And, the start of the first integration circuit for the current control is delayed with operation quantity signal generation circuit only at the time that the high-resolution evaluation or more than the start of the first integration circuit for the current control and corresponds to the voltage deviation.Type: ApplicationFiled: February 21, 2007Publication date: September 3, 2009Applicant: Nagasaki University, National University CorporationInventor: Fujio Kurokawa
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Publication number: 20090218553Abstract: The present invention is to provide an electromagnetic wave absorption (EWA) material for thermoforming having a good formability and high EWA performance. The EWA material for thermoforming contains a EWA particle covered with a thermoplastic resin layer.Type: ApplicationFiled: September 25, 2006Publication date: September 3, 2009Applicants: Yazaki Corporation, Nagasaki University National University CorporatioInventors: Shiyuuichi Kimura, Makoto Egashira, Kiyoshi Yagi, Takayuki Katou
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Publication number: 20090198069Abstract: An object of the present invention is to provide a novel metal complex. A metal complex having a composition of [(PtII)2(MI)4(L)8], where MI is H+, AgI, AuI or CuI, and L is a compound represented by the following chemical formula. A metal complex having a composition of [(PtII)2(MI)4(X)2(L)6], where MI is AgI, AuI or CuI, X is Cl?, Br? or I?, and L is a compound represented by the following chemical formula. In the formula, R1, R2 and R3 are independently a hydrogen atom, a chlorine atom, a bromine atom, an iodine atom, a hydroxyl group, a phenyl group, a trifluoromethylphenyl group, a pentafluorophenyl group, a naphthyl group, a methyl group, an ethyl group, an i-propyl group, a t-butyl group, a trifluoromethyl group, a hydroxymethyl group or a hydroxyethyl group. At least one of R1, R2 and R3 in the formula is not a hydrogen atom.Type: ApplicationFiled: March 24, 2006Publication date: August 6, 2009Applicant: NAGASAKI UNIVERSITY, NATIONAL UNIVERSITY CORPORATIInventors: Keisuke Umakoshi, Takashi Kojima, Seiji Akatsu, Masayoshi Onishi, Shoji Ishizaka, Noboru Kitamura
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Patent number: 7563395Abstract: A flame retardant is provided which has excellent dispersibility in resin ingredients and can give flame-retardant resin moldings excellent in flame retardancy and mechanical properties. The flame retardant comprises magnesium hydroxide particles, a higher fatty acid, preferably stearic acid, bonded to part of the surface of the magnesium hydroxide particles, and a silicone oil having reactivity bonded to that surface part of the magnesium hydroxide particles which does not have the higher fatty acid bonded thereto.Type: GrantFiled: April 20, 2005Date of Patent: July 21, 2009Assignees: Yazaki Corporation, Nagasaki UniversityInventors: Motoaki Iio, Koji Kodama, Shuichi Kimura, Kiyoshi Yagi, Makoto Egashira
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Publication number: 20090167393Abstract: The control accuracy equal with the case controlled according to a reference signal with a high clock frequency when the electric power is converted is obtained according to a reference signal with a low clock frequency. The quantity of signal S3 of the time that corresponds to the difference of EO in the output voltage to reference voltage EREF by circuit 12 of the generation of quantity of signal of time is generated synchronizing with reference timing signal S1. The phase generates the class of the phase-shift signal of n piece for which only [Cycle of S0/]/n is late one by one by phase-shift signal generation circuit 13, counter circuit 14, and digital addition circuit 15, these numbers are counted respectively, and the count value of n piece is added. The control signal S5 that corresponds to TON between when adding value ADD is input with decision circuit 16 of on time of the switch element and control signal generation circuit 17 and it turns it on is generated.Type: ApplicationFiled: February 21, 2007Publication date: July 2, 2009Applicant: NAGASAKI UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventor: Fujio Kurokawa
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Publication number: 20090047305Abstract: The present invention relates to a composition containing as its main component proanthocyanidin oligomer to which a substance having a phloroglucinol ring structure or resorcinol ring structure has been bonded, and reduced in the molecular weight, which is obtained by heating plant materials containing proanthocyanidin polymer or extract thereof with a substance having a phloroglucinol ring structure or resorcinol ring structure in an acidic aqueous solution, production method thereof, and uses of the composition in health products and pharmaceutical products. According to the invention, proanthocyanidin oligomer having physiological activity, to which a substance having a phloroglucinol ring structure or resorcinol ring structure has been bonded and reduced in the molecular weight to such a level that the oligomer can be absorbed into living body, which has been conventionally difficult to obtain at high yield from plant raw materials, can be produced efficiently and easily.Type: ApplicationFiled: February 24, 2006Publication date: February 19, 2009Applicants: NAGASAKI UNIVERSITY, USAIEN PHARMACEUTICAL CO., LTD., AMINO UP CHEMICAL CO., LTD.Inventors: Takashi Tanaka, Gen-ichiro Nonaka, Isao Kohno, Hajime Fujii, Takashi Nakagawa, Hiroshi Nishioka
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Publication number: 20080199856Abstract: The purpose of this invention is to provide a probe for diagnosis of Marfan syndrome, which enables early diagnosis of Marfan syndrome, and to provide a method for screening using said probe. The invention is a probe for a Marfan Syndrome characterized by using a nucleic acid comprising following (a) or (b); (a) a nucleic acid comprising a base sequence represented by base numbers 1-180000 shown in SEQ ID No. 1 of the sequence listing, or (b) a nucleic acid in which a part of the base sequence of said base numbers 1-180000 is deleted, substituted or added, and having 80% homology with said base sequence.Type: ApplicationFiled: May 27, 2005Publication date: August 21, 2008Applicant: NAGASAKI UNIVERSITYInventors: Norio Niikawa, Naomichi Matsumoto, Catherine Boileau, Gwenaielle Beroud, Guillaume Jondeau
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Publication number: 20080131367Abstract: A composition for diagnosing amyloid-related diseases, which comprises a flavone derivative, a chalcone derivative, a styrylchromone derivative, or a coumarin derivative, is provided. These compounds have high binding specificity to an amyloid ? protein, high permeability to a blood-brain barrier, and ability to rapidly disappear from sites other than cerebral senile plaque. Accordingly, the composition of the present invention using these compounds enables the diagnosis of amyloid-related diseases with high precision.Type: ApplicationFiled: November 25, 2005Publication date: June 5, 2008Applicants: NAGASAKI UNIVERSITYInventors: Hiroshi Mori, Morio Nakayama, Mamoru Haratake, Masahiro Ono
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Patent number: 7323301Abstract: A nucleic acid is (a) a nucleic acid comprising a base sequence shown in base numbers 1–39726 of SEQ ID NO: 1, or (b) a nucleic acid wherein a part of the bases 1–39726 of SEQ ID NO: 1 is deleted, substituted or added, and having a homology of 80% for the base sequence. Also, a probe comprises the above nucleic acid, and a screening is carried out by using such a probe.Type: GrantFiled: December 4, 2002Date of Patent: January 29, 2008Assignee: Nagasaki UniversityInventors: Naomichi Matsumoto, Norio Niikawa
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Publication number: 20070221891Abstract: A flame retardant is provided which has excellent dispersibility in resin ingredients and can give flame-retardant resin moldings excellent in flame retardancy and mechanical properties. The flame retardant comprises magnesium hydroxide particles, a higher fatty acid, preferably stearic acid, bonded to part of the surface of the magnesium hydroxide particles, and a silicone oil having reactivity bonded to that surface part of the magnesium hydroxide particles which does not have the higher fatty acid bonded thereto.Type: ApplicationFiled: April 20, 2005Publication date: September 27, 2007Applicants: Yazaki Corporation, Nagasaki UniversityInventors: Motoaki Iio, Koji Kodama, Shuichi Kimura, Kiyoshi Yagi, Makoto Egashira
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Patent number: 6943005Abstract: A cellophane agar medium is made of a cellophane piece with groove portions on at least one surface thereof and a nutritious agar formed on the surface of the cellophane piece via the groove portions. Then, the cellophane agar medium is disposed under wet condition, and a microbe is inoculated and cultivated on the cellophane agar medium. A fixing solution is added to the cellophane agar medium to fix the microbe to the cellophane agar medium. Thereafter, a given sample is made of the cellophane agar medium with the microbe and then, observed with a scanning electron microscope or a transmission electron microscope.Type: GrantFiled: October 14, 2003Date of Patent: September 13, 2005Assignee: Nagasaki UniversityInventor: Akitoyo Ichinose
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Publication number: 20050053583Abstract: By inhibiting expression of a normal prion protein in prion-infected cells by using siRNA, it is possible to inhibit accumulation of an abnormal prion protein consequently. The inhibition of the abnormal prion protein accumulation can be applied in prevention and treatment of the prion diseases. This provides a method of inhibiting the abnormal prion protein accumulation. This method is applicable in preventing and treating the prion diseases whose effective method of treating has not been established at this moment. Further, use of this method is provided herein.Type: ApplicationFiled: August 26, 2004Publication date: March 10, 2005Applicant: Nagasaki University, National University CorporationInventors: Suehiro Sakaguchi, Kazunari Taira
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Publication number: 20040241787Abstract: A cellophane agar medium is made of a cellophane piece with groove portions on at least one surface thereof and a nutritious agar formed on the surface of the cellophane piece via the groove portions. Then, the cellophane agar medium is disposed under wet condition, and a microbe is inoculated and cultivated on the cellophane agar medium. A fixing solution is added to the cellophane agar medium to fix the microbe to the cellophane agar medium. Thereafter, a given sample is made of the cellophane agar medium with the microbe and then, observed with a scanning electron microscope or a transmission electron microscope.Type: ApplicationFiled: October 14, 2003Publication date: December 2, 2004Applicant: NAGASAKI UNIVERSITYInventor: Akitoyo Ichinose
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Publication number: 20030162203Abstract: A nucleic acid is (a) a nucleic acid comprising a base sequence shown in a base sequence number 1-39726 of a sequence No.1 of a sequence table, or (b) a nucleic acid wherein a part of the base sequence of the base sequence number 1-39726 is deleted, substituted or added, and having a homology of 80% for the base sequence. Also, a probe comprises the above nucleic acid, and a screening is carried out by using such a probe.Type: ApplicationFiled: December 4, 2002Publication date: August 28, 2003Applicant: Nagasaki UniversityInventors: Naomichi Matsumoto, Norio Niikawa