Patents Assigned to Nagasaki University
  • Patent number: 8598858
    Abstract: The first sampling measurement value compares whether to exceed a prescribed threshold and judges the control part at the sampling time. The control part compares whether the first sampling measurement value exceeds a prescribed threshold. When the actual measurement value doesn't exceed a prescribed threshold, the control part predict the first sampling value at the next sampling time. [1] When the first sampling the predicting value doesn't exceed the threshold value, the status of the switch is maintained, [2] When the first sampling the predicting value exceeds the threshold value, the time when the movement of the switch should be changed is calculated and the status of the switch is changed at time concerned.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: December 3, 2013
    Assignee: Nagasaki University, National University Corporation
    Inventor: Fujio Kurokawa
  • Publication number: 20130253189
    Abstract: The present invention provides a metal complex containing a cation represented by [(MII)2(MI)2(LC)2(LB)4]2+ [in the aforementioned formula, MII is PtII or PdII, MI is H+, AuI, AgI, CuI, HgI, TlI or PbI, and LC and LB are ligands]. The metal complex of the present invention is useful as a light emitting material of an organic EL device.
    Type: Application
    Filed: September 15, 2011
    Publication date: September 26, 2013
    Applicant: Nagasaki University
    Inventors: Keisuke Umakoshi, Ami Higashitani, Kazutoyo Kimura, Shoji Ishizaka, Noboru Kitamura
  • Publication number: 20130203738
    Abstract: The present invention identifies a compound which binds to the PAH1 domain of mSin3B that specifically binds to neural restrictive silencer factor NRSF, and uses the compound as a prophylactic and/or a therapeutic for diseases associated with abnormal expression of neural restrictive silencer factor NRSF/REST or abnormal expression of genes targeted by NRSF/REST, such as Huntington's disease, medulloblastoma and neuropathic pain. The present invention provides a pharmaceutical composition comprising a substance capable of binding to the PAH1 domain of mSin3B, e.g.
    Type: Application
    Filed: February 9, 2011
    Publication date: August 8, 2013
    Applicants: NAGOYA CITY UNIVERSITY, NAGASAKI UNIVERSITY
    Inventors: Yoshifumi Nishimura, Aritaka Nagadoi, Yuuka Hirao, Yoshio Goshima, Naoya Yamashita, Naoki Miyata, Takayoshi Suzuki, Ryuta Hiraishi, Hiroshi Ueda
  • Patent number: 8493046
    Abstract: Disclosed herein is a control device for a DC/DC converter, in which FB control and FF control are combined to estimate an output voltage of a nonlinear dynamic system while guaranteeing stability. The control device includes a FB controller which generates a first time value for switch-off timing as the amount of feedback control, a machine learning controller which generates a second time value for switch-off timing as the amount of FF control, and a difference time calculator which obtains a difference between the first time value and the second time value and transmits a difference signal to the drive circuit.
    Type: Grant
    Filed: September 30, 2010
    Date of Patent: July 23, 2013
    Assignees: Nagasaki University, National University Corporation, Mitsubishi Electric Corporation
    Inventors: Fujio Kurokawa, Hiroyuki Osuga
  • Patent number: 8478395
    Abstract: The invention provides a method for evaluating a corneal disorder quantitatively and is applicable to living eyes. In particular, the invention provides a method for measuring a corneal transepithelial electric resistance, which method comprises: (1) a step of placing a first electrode on the cornea and a second electrode on the conjunctiva; and (2) a step of flowing an electric current between the first electrode and the second electrode to measure the electric resistance. The invention also provides a device for measuring a corneal transepithelial electric resistance value.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: July 2, 2013
    Assignees: Nagasaki University, Tohoku University
    Inventors: Masafumi Uematsu, Takashi Kitaoka, Koji Nishida, Yuji Tanaka, Matsuhiko Nishizawa, Hirokazu Kaji, Soichiro Sekine
  • Patent number: 8451631
    Abstract: To detect a peak time of an exciting current of a transformer, a primary current corresponding to the peak time, or a variation time of the primary voltage, and to switch a switch after expiration of a predetermined period from the peak time, after the peak time occurs. A control apparatus 1 is applied to a power conversion circuit 2 which includes a switch circuit 23 including one switch or a plurality of switches and a transformer 21. The control apparatus includes: an output voltage detector 11 detecting a value of an output voltage of the power conversion circuit; an exciting current peak time generator 12 detecting a peak time of an exciting current of the transformer; a timing generator 13 generating a switching timing of the one switch or the plurality of switches. The timing generator 13 generates the switching timing of the one switch or the plurality of switches on the basis of the output voltage and the peak time.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: May 28, 2013
    Assignee: Nagasaki University
    Inventor: Fujio Kurokawa
  • Publication number: 20130106383
    Abstract: By adding a suppression amount for suppressing an overshoot or undershoot that attenuates with time during an overshoot or undershoot period, the overshoot or undershoot can be suppressed within a short time and the output can be made close to a normal value. When an output has overshot, an overshoot suppression amount including a time-dependent attenuation suppression amount is added to an output feedback control amount, the time-dependent attenuation suppression amount being defined in a period during which the output overshoots. Alternatively, when the output has undershot, an undershoot suppression amount including a time-dependent attenuation suppression amount is added to the output feedback control amount, the time-dependent attenuation suppression amount being defined in a period during which the output undershoots.
    Type: Application
    Filed: January 31, 2011
    Publication date: May 2, 2013
    Applicants: NAGASAKI UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, MITSUBISHI ELECTRIC CORPORATION
    Inventors: Fujio Kurokawa, Hiroyuki Osuga
  • Publication number: 20130094259
    Abstract: It provides the effective power conversion control technique which it can control which it made use of a characteristic (nature) of each A/D converter in. It comprises the third control part including the third operating circuit it inputs signal from third A/D converter inputting the detecting signal which is different from the detecting signal which is the same as the detecting signal or the detecting signal and above third A/D converter, and to generate the third operating signal, and the above actuating management circuit manages the actuating of an above first control part and the second above control part and the third above control part.
    Type: Application
    Filed: March 31, 2011
    Publication date: April 18, 2013
    Applicant: Nagasaki University, National University Corporation
    Inventor: Fujio Kurokawa
  • Patent number: 8415893
    Abstract: Provided is a discharge lamp lighting device, which can control a load precisely while improving the practicability. When the difference of a count number (Nn) becomes a predetermined threshold value or less, a predictor circuit (35) predicts the timing, at which a current value (iQ1) becomes a peak value, on the basis of the rate of change of the difference. A switch selecting circuit (38), which is driven with a clock frequency higher than the sampling frequency of a first converter unit (32), turns off a field effect transistor (Q1) at the turn-off timing, and turns on a field effect transistor (Q2). A plurality of A/D converters (37a) are subjected to a multi-rate control, thereby to correct the threshold value of the predictor circuit (35) on the basis of the peak value of a lamp current (iOUT).
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: April 9, 2013
    Assignee: Nagasaki University
    Inventor: Fujio Kurokawa
  • Patent number: 8415399
    Abstract: An infection inhibitor of retrovirus, particularly human immunodeficiency virus, comprising, as an active ingredient, at least one compound selected from the group consisting of a compound represented by the formula (I) (GGA) or a salt thereof, a compound represented by the formula (II) (NIK-333) or a salt thereof, and derivatives thereof.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: April 9, 2013
    Assignees: Nagasaki University, Kowa Company, Ltd.
    Inventors: Yoshinao Kubo, Haruka Kamiyama
  • Publication number: 20130060015
    Abstract: The present invention relates to methods for producing glucosides directly from glucose or a polysaccharide comprising glucose as a structural unit. The present invention provides a method comprising reacting glucose or a polysaccharide comprising glucose as a structural unit with a compound represented by R—OH in the presence of a supercritical or subcritical carbon dioxide to produce glucosides and a method comprising dissolving or suspending glucose or a polysaccharide comprising glucose as a structural unit in an organic solvent containing a compound represent by R—OH and reacting the glucose or polysaccharide with the compound represented by R—OH in the presence of a supercritical or subcritical carbon dioxide to produce glucosides.
    Type: Application
    Filed: May 13, 2011
    Publication date: March 7, 2013
    Applicants: JX NIPPON OIL & ENERGY CORPORATION, NAGASAKI UNIVERSITY
    Inventors: Suguru Motokucho, Toshio Inoue
  • Publication number: 20130052127
    Abstract: The invention provides an antigen or drug delivery complex containing a complex of an antigen or drug and a cationic molecule, and an anionic molecule encapsulating the same. The antigen or drug delivery complex can be used as a main component of a drug delivery system that delivers various antigens and drugs to a particular cell or organ.
    Type: Application
    Filed: February 24, 2011
    Publication date: February 28, 2013
    Applicants: NAGASAKI UNIVERSITY, National University Corporation Hamamatsu University School of Medicine, KYUSYU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
    Inventors: Hitoshi Sasaki, Tomoaki Kurosaki, Takashi Kitahara, Hideto To, Katsuyuki Yui, Kenji Hirayama, Kouichi Morita, Takahiro Mukai, Yasuhiro Magata, Mikako Ogawa, Kohei Sano
  • Publication number: 20130052678
    Abstract: The invention provides a method of detecting uracil. The method comprises reacting uracil with a compound represented by the formula (I) in the presence of an oxidant and a base to produce a fluorescent compound represented by the formula (II).
    Type: Application
    Filed: March 1, 2011
    Publication date: February 28, 2013
    Applicant: NAGASAKI UNIVERSITY
    Inventors: Masaaki Kai, Takayuki Shibata
  • Publication number: 20120326751
    Abstract: The frequency decision device determines frequency of the measured rectangular signal by simple and easy means. The frequency decision device inputs the measured rectangular signal that frequency (or period) changes dynamically. It generates a rectangular reference signal of predetermined on width ? synchronizing to the edge based on a positive going edge of this measured rectangle signal. And it watches the order of measured rectangle signal and falling edges of the rectangular reference signal. When this sequential order reversed, it detects that length of the ON time of ON time of the measured rectangle signal and the measured rectangular signal reversed.
    Type: Application
    Filed: September 30, 2010
    Publication date: December 27, 2012
    Applicant: Nagasaki University, National University Corporation
    Inventor: Fujio Kurokawa
  • Patent number: 8314642
    Abstract: A rising edge or a falling edge is finely adjusted, or a dead time and a period are adjusted with high accuracy. A waveform processing circuit includes: an integration circuit 11 receiving a rectangular or substantially-rectangular pulse and outputting a gradually increasing or decreasing signal obtained by integrating the pulse signal; a reference signal output circuit 12 outputting a constant value or a varying value as a reference signal; and a comparison circuit 13 comparing the output of the integration circuit with the output of the reference signal output circuit and outputting a pulse rising or falling at a timing when the difference between the outputs varies.
    Type: Grant
    Filed: June 1, 2008
    Date of Patent: November 20, 2012
    Assignee: Nagasaki University
    Inventor: Fujio Kurokawa
  • Publication number: 20120243265
    Abstract: Disclosed herein is a control device for a DC/DC converter, in which FB control and FF control are combined to estimate an output voltage of a nonlinear dynamic system while guaranteeing stability. The control device includes a FB controller which generates a first time value for switch-off timing as the amount of feedback control, a machine learning controller which generates a second time value for switch-off timing as the amount of FF control, and a difference time calculator which obtains a difference between the first time value and the second time value and transmits a difference signal to the drive circuit.
    Type: Application
    Filed: September 30, 2010
    Publication date: September 27, 2012
    Applicants: MITSUBISHI ELECTRIC CORPORATION, NAGASAKI UNIVERSITY NATIONAL UNIVERSITY CORPORATIO
    Inventors: Fujio Kurokawa, Hiroyuki Osuga
  • Patent number: 8248131
    Abstract: There are provided a timing generating circuit which can generate the rising edge or the falling edge of pulses with a resolution higher than the frequency of a repeat signal generating circuit, and a phase shift circuit which can be applied to the timing generating circuit. The phase shift circuit receiving a repeat signal generates a signal of which a phase is shifted by a predetermined quantity on the basis of the repeat signal, the phase shift controller controls what phase of signal the phase shift circuit output among first to M-th signals, and the counter circuit counts the number of output signals of the phase shift circuit and generates a count end signal when the count value reaches a set value, and thereby the counter circuit outputs a synthesized timing signal of the timing of the repeat signal and the timing shifted by the phase shift circuit.
    Type: Grant
    Filed: June 1, 2008
    Date of Patent: August 21, 2012
    Assignee: Nagasaki University, National University Corporation
    Inventor: Fujio Kurokawa
  • Publication number: 20120183972
    Abstract: The invention provides nucleotide sequences that function as enhancers and induce osteoblast-specific expression, expression vectors comprising such an enhancer, a promoter, and a gene containing a coding region, as well as screening methods utilizing such expression vectors.
    Type: Application
    Filed: August 6, 2010
    Publication date: July 19, 2012
    Applicant: NAGASAKI UNIVERSITY
    Inventors: Toshihisa Komori, Shinichi Izumi, Toshihiro Miyazaki, Satoshi Rokutanda, Hisato Komori, Wenguang Liu
  • Publication number: 20120165259
    Abstract: The invention provides a method of ameliorating a blood-brain barrier disorder, as well as a method of treating a disease accompanied by a blood-brain barrier disorder and a method of treating a cerebral ischemic disease, by administering a prothymosin ?, or a protein or polypeptide possessing the same function as the prothymosin ?. The invention also provides polypeptides useful in the context of the aforesaid methods.
    Type: Application
    Filed: August 9, 2010
    Publication date: June 28, 2012
    Applicant: NAGASAKI UNIVERSITY
    Inventor: Hiroshi Ueda
  • Publication number: 20120161551
    Abstract: A reluctance motor according to an aspect of an embodiment includes a stator and a mover. One of the stator and the mover includes a plurality of magnetic poles on which coils are wound. The other of the stator and the mover includes a magnetic segment that includes a directivity member of which the magnetization direction is regulated in a predetermined direction and that is embedded into a non-magnetic holder.
    Type: Application
    Filed: December 6, 2011
    Publication date: June 28, 2012
    Applicants: Nagasaki University, Kabushiki Kaisha Yaskawa Denki
    Inventors: Yasuhiro MIYAMOTO, Motomichi Ohto, Tsuyoshi Higuchi