Patents Assigned to Nagoya Industrial Science Research Institute
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Publication number: 20070178584Abstract: A culture device to apply uniform stress to cells is proposed. A culture device is formed in a rectangular box shape from a deformable material, comprising a bottom membrane and side walls upstanding from the entire periphery of said bottom membrane, wherein an engaging member is formed in opposing side walls on a line extended from a peripheral edge of said bottom membrane. By providing the latching member in the culture membrane so as to latch the cells to the latching member, the slippage between the bottom membrane and sample cells is forestalled upon the extension of the culture membrane.Type: ApplicationFiled: March 9, 2005Publication date: August 2, 2007Applicant: NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTEInventors: Keiji Naruse, Norio Ishida
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Patent number: 7246979Abstract: A flat portion 12a and a slope portion 12b are provided on a thread 12 of a multi-pitch screw 10 alternately. The flat portion and the slope portion are provided on the thread of a multi-pitch nut which fastens with this. Consequently, a screw and a nut capable of preventing loosening securely by step are achieved. This enables comfortable and quick feeding and when a torque from a driving source is interrupted, step-like self-lock is activated.Type: GrantFiled: October 22, 2003Date of Patent: July 24, 2007Assignees: Kabushiki Kaisha Imasen Denki Seisakusho, Nagoya Industrial Science Research InstituteInventors: Hiroshi Fujii, Katsuhiro Sugiyama, Masashi Mitsukuchi, Kenichi Katayama, Yoshinori Moriguchi
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Publication number: 20070090292Abstract: A semiconductor radiation detector 10 comprises a Si substrate 11 of an N-ype of low resistance, an arsenic coating layer 12 formed on the Si substrate, and a CdTe growth layer 13 of a P-type of high resistance laminated and formed thereon by the MOVPE method, which is divided into multiple plane elements of a hetero junction structure by means of division grooves 15 extending from the CdTe growth layer surface to the Si substrate. The Si substrate is heated in a hydrogen reducing atmosphere of a high temperature, and its surface is cleaned. On this Si substrate, GaAs powder or GaAs crystals are thermally decomposed, and coated by arsenic molecule to an extent at about one molecular layer, and an arsenic coating layer is thereby formed. On the Si substrate forming the arsenic coating layer, a CdTe growth layer is formed by the MOVPE method to a film thickness of about 0.2 to 0.5 mm in an atmosphere of about 450 to 500 deg. C.Type: ApplicationFiled: November 24, 2004Publication date: April 26, 2007Applicant: NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTEInventors: Kazuhito Yasuda, Madan Niraula
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Patent number: 7161437Abstract: A ring oscillator of an even number of stages of inverting/summing amplifiers that adds, to an input of each of the amplifiers, a signal from one such of the amplifiers as to be distant by an even number of stages therefrom, to realize a desired oscillation operation, thereby directly generating signals having phases shifted by 90 degrees from each other. Further, the signals in the ring oscillator are complementary to each other, so that by arranging these signals close to each other in a wiring, it is possible to realize low sensitivity to a mixed external signal.Type: GrantFiled: August 19, 2003Date of Patent: January 9, 2007Assignee: Nagoya Industrial Science Research InstituteInventor: Akihiko Yoneya
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Patent number: 7119065Abstract: We claim a metal complex-protein composite comprising a salen metal complex and an apoprotein having a cavity, wherein the salen metal complex has a structure given by the following formula: R1 and R5 each independently represents an alkyl group containing 1 to 5 carbon atoms; and R2 through R4 and R6 through R10 each represents a hydrogen atom.Type: GrantFiled: April 26, 2004Date of Patent: October 10, 2006Assignee: Nagoya Industrial Science Research InstituteInventors: Takafumi Ueno, Yoshihito Watanabe, Masataka Ohashi, Tomomi Koshiyama, Norihiko Yokoi
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Patent number: 7060803Abstract: A metal complex-protein composite comprising apohemoglobin, apoheme oxygenase, apocatalase or apoferrin having cavity and a metal complex has a specific structure that the metal complex is received in the cavity of the apoprotein. The metal complex is prepared by complexation of a metal ion, which is selected from the group consisting of rhodium, ruthenium, and palladium, with a ligand. The metal complex-protein composite functions as a hydrogenation catalyst of an olefin in water. The metal complex-protein composite is thus effectively applied to hydrogenation of water-soluble subtrates and has enviromental advantages over organic solvents.Type: GrantFiled: March 2, 2004Date of Patent: June 13, 2006Assignee: Nagoya Industrial Science Research InstituteInventors: Yoshihito Watanabe, Takafumi Ueno, Satoshi Abe
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Publication number: 20060099594Abstract: It is intended to provide a means of predicting genetic risk for hypertension at a high accuracy and high prediction possibility. Namely, risk for hypertension is predicted by a method involving the following steps: (i) the step of analyzing two or more polymorphisms selected from among 4 gene polymorphisms having been revealed as relating to hypertension; (ii) the step of determining the genotype of a nucleic acid sample based on the polymorphism data obtained in the above step; and (iii) the step of predicting the genetic risk for hypertension from the genotype thus determined.Type: ApplicationFiled: September 22, 2003Publication date: May 11, 2006Applicant: NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTEInventors: Yoshiji Yamada, Mitsuhiro Yokota
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Patent number: 6980974Abstract: The expression data of specimen genes are processed using the SWEEP operator method and the parameter increasing method, and genes are selected. A FNN model is constructed by making the expression data of the selected genes as input variables.Type: GrantFiled: December 18, 2002Date of Patent: December 27, 2005Assignee: Nagoya Industrial Science Research InstituteInventors: Takeshi Kobayashi, Hiroyuki Honda, Taizo Hanai, Tatsuya Ando
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Publication number: 20050225400Abstract: A ring oscillator of an even number of stages of inverting/summing amplifiers that adds, to an input of each of the amplifiers, a signal from one such of the amplifiers as to be distant by an even number of stages therefrom, to realize a desired oscillation operation, thereby directly generating signals having phases shifted by 90 degrees from each other. Further, the signals in the ring oscillator are complementary to each other, so that by arranging these signals close to each other in a wiring, it is possible to realize low sensitivity to a mixed external signal.Type: ApplicationFiled: August 19, 2003Publication date: October 13, 2005Applicant: NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTEInventor: Akihiko Yoneya
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Publication number: 20050208466Abstract: A method for selectively isolating or visualizing a target cell differentiated from an embryonic stem cell, which comprises transferring a first recombinant DNA in which a first promoter, a gene having recombinase recognition sequences on both ends, and a selective marker gene of a target cell differentiated from an embryonic stem cell are arranged in this order from a 5? side, and the first promoter makes the selective marker gene express, and a second recombinant DNA in which a second promoter specifically expressing in a target cell differentiated from an embryonic stem cell, and a recombinase-expressing gene are arranged in this order from a 5? side, respectively into an embryonic stem cell. A kit for isolation or visualization, which comprises the first vector for transferring a gene containing a first DNA and the second vector for transferring a gene containing a second DNA.Type: ApplicationFiled: June 13, 2003Publication date: September 22, 2005Applicant: Nagoya Industrial Science Research InstituteInventors: Kenichiro Kosai, Tomoyuki Takahashi
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Patent number: 6925236Abstract: A broadband optical spectrum generating apparatus 20 includes a ultrashort pulsed fiber laser 22 that generates pulsed light having a pulse width in the unit of picosecond to femtosecond, and broadband optical spectrum-generating optical fibers 24 that are connected with the ultrashort pulse fiber laser 22 via a lens 26 and have characteristics of normal dispersion, that is, a nonlinear coefficient of not less than 10 [W?1 km?1] and a magnitude of wavelength dispersion of not greater than a value 0 [ps/km/nm] with regard to a wavelength of the pulsed light. The resulting output is super continuum that is widely broadened to a wavelength band of 1400 nm to 1750 nm and is chirped to a linear characteristic.Type: GrantFiled: August 30, 2002Date of Patent: August 2, 2005Assignees: Nagoya Industrial Science Research Institute, Aisin Seiki Kabushiki KaishaInventors: Toshio Goto, Norihiko Nishizawa, Youta Ito
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Publication number: 20050096260Abstract: The metal complex-protein composite of the invention has a specific structure that a salen metal complex expressed by Formula (1) given below is received in a cavity of a protein: where M in Formula (1) represents a metal ion, and R1 through R10 independently represent any of hydrogen atom, halogen atoms, alkyl groups containing 1 to 5 carbon atoms, and alkoxy groups containing 1 to 5 carbon atoms.Type: ApplicationFiled: April 26, 2004Publication date: May 5, 2005Applicant: NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTEInventors: Takafumi Ueno, Yoshihito Watanabe, Masataka Ohashi, Tomomi Koshiyama, Norihiko Yokoi
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Patent number: 6884364Abstract: A lead-free piezoelectric ceramic composition wherein a suitable amount of Cu is contained in a perovskite compound of a non-stoichiometric composition represented by a formula (KxA1-x)y(Nb1-zBz)O3, wherein “A” represents at least one of Na and Bi, while “B” represents at least one of Ta and Ti, and wherein 0<x?1, 0<y<1, and 0?z?1, so that by-products such as KaCubNbcOd and KaCubTacOd are produced as a result of reaction of (Nb1-zBz) with Cu in the process of calcination of a starting material, and the by-products restrict melting and abnormal grain growth of (KxNa1-x)(Nb1-zTaz) O3 during firing of a calcined body, thereby improving sinterability of the fired body, while restricting volatilization of alkali components and melting of KNbO3, thereby increasing the density and improving the piezoelectric properties of the fired body.Type: GrantFiled: September 23, 2003Date of Patent: April 26, 2005Assignees: Noritake Co., Limited, Nagoya Industrial Science Research InstituteInventors: Fuyutoshi Sato, Shin-ichi Hirano, Masato Matsubara, Wataru Sakamoto, Toshinobu Yogo, Koichi Kikuta
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Publication number: 20050049405Abstract: The metal complex-protein composite of the present invention includes a protein having a cavity and a metal complex and has a specific structure that the metal complex is received in the cavity of the protein. Here the metal complex is prepared by complexation of a metal ion, which is selected among the group consisting of rhodium, ruthenium, and palladium, with a ligand. The metal complex-protein composite of the invention functions as a hydrogenation catalyst of an olefin in water. The metal complex-protein composite is thus effectively applied to hydrogenation of water-soluble substrates and has environmental advantages over organic solvents.Type: ApplicationFiled: March 2, 2004Publication date: March 3, 2005Applicant: Nagoya Industrial Science Research InstituteInventors: Yoshihito Watanabe, Takafumi Ueno, Satoshi Abe
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Patent number: 6813423Abstract: A broadband optical spectrum generating apparatus 20 includes an ultra-short pulse fiber laser 22 that generates pulsed light having a pulse width in a unit of picosecond to femtosecond, and a broadband optical spectrum-generating optical fiber 24 that is connected with the ultra-short pulse fiber laser 22 via a lens 26 and has a non-linear coefficient of not less than 10 [W−1m−1] at a wavelength of the pulsed light and a magnitude of chromatic dispersion of not greater than 2 [ps/km/nm]. The pulsed light emitted from the ultra-short pulse fiber laser 22 is converted into a relatively flat super continuum over a broad band of approximately 1200 nm to 2000 nm by chromatic dispersion in the course of transmission through the broadband optical spectrum-generating optical fiber 24.Type: GrantFiled: August 26, 2003Date of Patent: November 2, 2004Assignee: Nagoya Industrial Science Research InstituteInventors: Toshio Goto, Norihiko Nishizawa
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Publication number: 20040176945Abstract: A finite state transducer generator includes a recursive transition network creating part that creates a recursive transition network, an arc replacement part that recursively repeats an operation where an arc in a finite state transducer is replaced by a network corresponding to an input label of the arc by a network in the recursive transition network, and a priority calculating part that calculates an arc replacement priority based on statistical information regarding frequency of applying grammar rules. The arc replacement part replaces arcs in descending order of arc replacement priority. Therefore, the finite state transducer generator can generate a finite state transducer capable of parsing a considerable great number of sentences within a limited size.Type: ApplicationFiled: September 15, 2003Publication date: September 9, 2004Applicant: Nagoya Industrial Science Research InstituteInventors: Yasuyoshi Inagaki, Shigeki Matsubara, Yoshihide Kato, Keiichi Minato
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Publication number: 20040127344Abstract: A lead-free piezoelectric ceramic composition wherein a suitable amount of Cu is contained in a perovskite compound of a non-stoichiometric composition represented by a formula (KxA1−x)y(Nb1−zBz)O3, wherein “A” represents at least one of Na and Bi, while “B” represents at least one of Ta and Ti, and wherein 0<x≦1, 0<y<1, and 0≦z≦1, so that by-products such as KaCubNbcOd and KaCubTacOd are produced as a result of reaction of (Nb1−zBz) with Cu in the process of calcination of a starting material, and the by-products restrict melting and abnormal grain growth of (KxNa1-x)(Nb1−zTaz) O3 during firing of a calcined body, thereby improving sinterability of the fired body, while restricting volatilization of alkali components and melting of KNbO3, thereby increasing the density and improving the piezoelectric properties of the fired body.Type: ApplicationFiled: September 23, 2003Publication date: July 1, 2004Applicants: NORITAKE CO., LIMITED, NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTEInventors: Fuyutoshi Sato, Shin-ichi Hirano, Masato Matsubara, Wataru Sakamoto, Toshinobu Yogo, Koichi Kikuta
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Publication number: 20040105637Abstract: A broadband optical spectrum generating apparatus 20 includes an ultra-short pulse fiber laser 22 that generates pulsed light having a pulse width in a unit of picosecond to femtosecond, and a broadband optical spectrum-generating optical fiber 24 that is connected with the ultra-short pulse fiber laser 22 via a lens 26 and has a non-linear coefficient of not less than 10 [W−1m−1] at a wavelength of the pulsed light and a magnitude of chromatic dispersion of not greater than 2 [ps/km/nm]. The pulsed light emitted from the ultra-short pulse fiber laser 22 is converted into a relatively flat super continuum over a broad band of approximately 1200 nm to 2000 nm by chromatic dispersion in the course of transmission through the broadband optical spectrum-generating optical fiber 24.Type: ApplicationFiled: August 26, 2003Publication date: June 3, 2004Applicant: NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTEInventors: Toshio Goto, Norihiko Nishizawa
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Patent number: 6720439Abstract: trans-RuH(&eegr;1-BH4)[(S)-xylbinap][(S,S)-dpen] (0.00125 mmol), acetophenone (5.0 mmol), and 2-propanol (2.5 mL) were placed in an autoclave, and the resulting solution was repeatedly subject 5 times to a procedure of performing pressure reduction and argon introduction while stirring the solution for deaeration. A hydrogen tank was then connected to the autoclave, and after replacing the air inside an introduction tube with hydrogen, the pressure inside the autoclave was adjusted to 5 atmospheres and then hydrogen was released until the pressure dropped to 1 atmosphere. After repeating this procedure 10 times, the hydrogen pressure was adjusted to 8 atmospheres and stirring at 25° C. was performed for 12 hours. By concentrating the solution obtained by depressurization and subjecting the crude product to simple distillation, (R)-1-phenylethanol (yield: 95%) in the form of a colorless oily substance was obtained at an ee of 99%.Type: GrantFiled: November 12, 2002Date of Patent: April 13, 2004Assignee: Nagoya Industrial Science Research InstituteInventors: Takeshi Ohkuma, Masatoshi Koizumi, Kilian Muñiz, Ryoji Noyori
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Publication number: 20030233196Abstract: The expression data of specimen genes are processed using the SWEEP operator method and the parameter increasing method, and genes are selected. A FNN model is constructed by making the expression data of the selected genes as input variables.Type: ApplicationFiled: December 18, 2002Publication date: December 18, 2003Applicant: NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTEInventors: Takeshi Kobayashi, Hiroyuki Honda, Taizo Hanai, Tatsuya Ando