Patents Assigned to National Taiwan University
  • Publication number: 20240085369
    Abstract: Disclosed is a self-powered formaldehyde sensing device, comprising: a triboelectric material electrode layer including a first substrate and a first electrode layer formed on the first substrate; a triboelectric material dielectric layer including a second substrate, a second electrode layer formed on the second substrate, a dielectric reacting layer formed on the second electrode layer, and a reaction modification layer formed on the dielectric reacting layer to surface-modify the dielectric reacting layer, the reaction modification layer being a phosphomolybdic acid complex (cPMA) layer, the phosphomolybdic acid complex of the phosphomolybdic acid complex layer being obtained by dissolving 4,4?-bipyridine (BPY) in isopropanol (IPA) and then mixing with phosphomolybdic acid (PMA) solution; an elastic spacer; and an external circuit.
    Type: Application
    Filed: December 21, 2022
    Publication date: March 14, 2024
    Applicant: National Taiwan University of Science and Technology
    Inventors: Chih-Yu Chang, Chun-Yi Ho, Yu-Hsuan Cheng, Ying-Ying Chen
  • Publication number: 20240081732
    Abstract: The present invention discloses a method of detecting sleep disorder based on an EEG signal and device of the same. The method and device only need an EEG signal for analysis to determine sleep disorder and abnormal score. Therefore, the method and device may reduce cost of collecting physical information and avoid from uncomfortable feeling of user who wears several sensors.
    Type: Application
    Filed: September 12, 2023
    Publication date: March 14, 2024
    Applicant: National Taiwan University
    Inventors: Phone LIN, XIN-XUE LIN
  • Patent number: 11925650
    Abstract: The present invention provides an antibacterial chemical compound, its manufacturing method and its use thereof which acts as antibacterial agents being useful for treating a disease or condition characterized by infectious disease, such as gastroenteritis and invasive non-typhoidal Salmonellosis, and also providing a new therapeutic option for patients infected by the bacteria with the resistance to antibiotics.
    Type: Grant
    Filed: March 4, 2022
    Date of Patent: March 12, 2024
    Assignees: NATIONAL TAIWAN UNIVERSITY, NATIONAL YANG MING CHIAO TUNG UNIVERSITY
    Inventors: Hao-Chieh Chiu, Chung-Wai Shiau
  • Patent number: 11925727
    Abstract: An intervertebral fusion device includes a structural ceramic body. The structural ceramic body has a bottom surface, a top surface, a peripheral surface connected between the bottom surface and the top surface, and at least one pore channel penetrating the bottom surface and the top surface. The inner surface of the pore channel is either a convex curved surface or a funnel-shaped surface. For the pore channel having the convex curved surface, the pore diameter of the pore channel gradually expands from the center of the pore channel to the top surface and the bottom surface. The pore diameter can also gradually expand from the bottom surface to the top surface. The peripheral surface of the structural ceramic body is wavy or zigzag.
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: March 12, 2024
    Assignee: National Taiwan University
    Inventor: Wei-Hsing Tuan
  • Patent number: 11919886
    Abstract: The present disclosure provides compounds of Formulas (I), (II), and pharmaceutically acceptable salts thereof. The compounds described herein are useful in treating proliferative diseases, for example, cancer (e.g., lung cancer), and infectious diseases (e.g., bacterial infections).
    Type: Grant
    Filed: July 12, 2022
    Date of Patent: March 5, 2024
    Assignees: Academia Sinica, National Taiwan University
    Inventors: Chi-Huey Wong, Pan-Chyr Yang, Rong-Jie Chein, Szu-Hua Pan, Ting-Jen R. Cheng
  • Publication number: 20240068043
    Abstract: Provided is a method for diagnosing and monitoring progression of cancer or effectiveness of a therapeutic treatment. The method includes detecting a methylation level of at least one gene in a biological sample containing circulating free DNA. Also provided are primer pairs and probes for diagnosis or prognosis of cancer in a subject in need thereof.
    Type: Application
    Filed: March 1, 2022
    Publication date: February 29, 2024
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Hsing-Chen TSAI, Chong-Jen YU, Hsuan-Hsuan LU, Shu-Yung LIN, Yi-Jhen HUANG, Chen-Yuan DONG
  • Patent number: 11910791
    Abstract: A graded early warning system for pest quantity counting includes: at least one image capturing device used to capture images of at least one pest trapping device in an environment to generate at least one pest trapping image; at least one environment monitoring and sensing device used to detect the environment to generate at least one environment parameter; at least one pest detecting and identifying device used to detect quantities and species of multiple pests based on the at least one pest trapping image; and a cloud server used to receive the at least one pest trapping image, the at least one environment parameter, and the quantities and species of multiple pests; wherein the cloud server immediately establishes pest probability models, generates early warning signals, and prompts suppression decisions according to the at least one environment parameter and the quantities and species of multiple pests.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: February 27, 2024
    Assignee: National Taiwan University
    Inventors: Ta-Te Lin, Dan Jeric Arcega Rustia, Lin-Ya Chiu
  • Patent number: 11913030
    Abstract: The present disclosure provides a method of preparing mimicking angiogenic co-spheroids, including: co-cultring a neural related cell and a cultured cell on hyaluronan-grafted chitosan (CS-HA) substrates to form a co-spheroid of neural related cell/cultured cell, and encapsulating the co-spheroid of neural related cell/cultured cell into a hydrogel to form a mimicking angiogenic co-spheroid. The mimicking angiogenic co-spheroid of the present disclosure can be formed by 3D printing model as a 3D mini-neurovascular unit, which is applicated to a high-throughput angiogenesis screening platform.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: February 27, 2024
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Shan-Hui Hsu, Hao-Wei Han
  • Publication number: 20240058400
    Abstract: An isolated bacterial strain of Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 deposited under the DSMZ Accession No. DSM 34213 is provided; a probiotic composition including an Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 and optionally, one or more additional probiotic organisms that enhance the probiotic activity of the Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 is also provided; and a method for preventing or treating chronic kidney disease in a subject in need thereof including: administering to the subject a pharmaceutically effective amount of the probiotic composition including an isolated bacterial strain of Lactiplantibacillus plantarum subsp. plantarum MFM 30-3, and optionally, one or more additional probiotic organisms that enhance the probiotic activity of the Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 is further provided.
    Type: Application
    Filed: November 6, 2023
    Publication date: February 22, 2024
    Applicant: National Taiwan University
    Inventors: Ming-Ju Chen, Hsiao-Wen Huang
  • Publication number: 20240063284
    Abstract: A method includes forming an epitaxial stack over a semiconductor substrate, wherein the epitaxial stack comprises a plurality of sacrificial layers and a plurality of channel layers alternately arranged over the semiconductor substrate, and each of the sacrificial layers is a multi-layer film comprising a bottom epitaxial layer, a middle epitaxial layer over the bottom epitaxial layer, and a top epitaxial layer over the middle epitaxial layer, wherein the middle epitaxial layer has a lower germanium concentration than the bottom and top epitaxial layers; laterally recessing the sacrificial layers to form sidewall recesses alternating with the channel layers; forming inner spacers in the sidewall recesses; forming source/drain epitaxial structures on opposite sides of the channel layers.
    Type: Application
    Filed: August 17, 2022
    Publication date: February 22, 2024
    Applicants: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Chien-Te TU, Chee-Wee LIU
  • Patent number: 11908892
    Abstract: A device comprises source/drain regions over a substrate and spaced apart along a first direction, a first gate structure between the source/drain regions, and a first channel structure surrounded by the first gate structure. The first channel structure comprises alternately stacking first semiconductor layers and second semiconductor layers. When viewed in a cross section taken along a second direction perpendicular to the first direction, central axes of the second semiconductor layers are laterally offset from central axes of the first semiconductor layers.
    Type: Grant
    Filed: July 9, 2021
    Date of Patent: February 20, 2024
    Assignees: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Hung-Yu Ye, Yu-Shiang Huang, Chien-Te Tu, Chee-Wee Liu
  • Publication number: 20240055033
    Abstract: A computing-in-memory circuitry includes multiple digital-to-analog converters, multiple computing arrays, and multiple charge processing networks. The digital-to-analog converters convert external data into input data and the digital-to-analog converters are connected in series with a corresponding plurality of output capacitor pairs. The computing arrays receive the input data from both ends and execute a computation to output a first computing value. The charge processing networks receive and accumulate the first computing values over a predetermined time interval through switching pairs in series with the output capacitor pairs. The charge processing networks evenly distribute charges of the first computing value to selected output capacitor pairs and compare voltage differences between two ends of the output capacitor pairs to output a second computing value.
    Type: Application
    Filed: August 9, 2022
    Publication date: February 15, 2024
    Applicant: National Taiwan University
    Inventors: Ying-Tuan Hsu, Tsung-Te Liu, Tzi-Dar Chiueh
  • Patent number: 11899194
    Abstract: A margin assessment method is provided. Under cooperation of harmonic generation microscopy (HGM) and a deep learning method, the margin assessment method can instantaneously and digitally determine whether a 3D image group generated by an HGM imaging system is a malignant tumor or the surrounding normal skin, so as to assist in determining margins of a lesion.
    Type: Grant
    Filed: October 20, 2021
    Date of Patent: February 13, 2024
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Chi-Kuang Sun, Yi-Hua Liao, Chia-I Chen
  • Patent number: 11896340
    Abstract: A robot navigation system includes a handheld robot, a spatial information measuring device, a computing module and a display. The hand-held robot has a body, a tool and a movable connection mechanism. The movable connection mechanism is connected between the body and the tool, so that the tool can move relative to the body. The spatial information measuring device is configured to track the body, the tool and a target. The computing module is connected to the spatial information measuring device to obtain a plurality of relative positions between the body, the tool and the movable connection mechanism with respect to the target. The computing module calculates a guiding region according to the relative positions and mechanical parameters of the handheld robot. The display is configured to display the guiding region and the handheld robot based on the coordinate of the target.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: February 13, 2024
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Ping-Lang Yen, Tsung-Han Ho
  • Patent number: 11898010
    Abstract: Present invention is related to a polyimide of formula as following: and a ketone-containing alicyclic dianhydride of formula as following: wherein: R1, R2, R3, R4 denote hydrogen atom or carbon containing functional group with carbon number at a range of 1-4; R5 denotes diamine group; and n equals to any positive integer.
    Type: Grant
    Filed: July 23, 2021
    Date of Patent: February 13, 2024
    Assignee: National Taiwan University of Science and Technology
    Inventors: Jyh-Chien Chen, Hsiang Jung Lee, Kai-Cheng Zhong
  • Publication number: 20240049212
    Abstract: A method for performing radio resource allocation in a TN-NTN mixed system is provided. The system includes a satellite that covers an NTN cell, and a plurality of TN base stations (TN BSs) within a coverage of the satellite. The NTN cell serves a plurality of NTN user equipments (NTN UEs). The method includes dividing the plurality of NTN UEs into X NTN UE groups; partitioning a radio resource into M parts, where M?X; dividing the plurality of TN BSs into M TN BS groups; deciding radio resource allocation regarding the plurality of NTN UEs, by allocating an i-th part of the radio resource to an i-th NTN UE group, where i=1, 2, . . . , X; and deciding radio resource allocation regarding the plurality of TN BSs, by allocating a sum of a j-th to an M-th parts of the radio resource to a j-th TN BS group, where j=1, 2, . . . , M.
    Type: Application
    Filed: July 20, 2023
    Publication date: February 8, 2024
    Applicants: MEDIATEK INC., National Taiwan University
    Inventors: Hao-Wei LEE, I-Kang FU, Chun-Chia CHEN, Chen-I LIAO, Hung-Yu WEI
  • Publication number: 20240049273
    Abstract: This disclosure provides a method, an apparatus, and a non-transitory computer-readable medium for radio resource allocation for a terrestrial network (TN) cell. In the method, the TN cell is determined to be outside a coverage of a first non-terrestrial network (NTN) cell. In response to the TN cell being outside the coverage of the first NTN cell, a radio resource is allocated to the TN cell based on a radio resource of the first NTN cell.
    Type: Application
    Filed: July 28, 2023
    Publication date: February 8, 2024
    Applicants: MEDIATEK INC., National Taiwan University
    Inventors: Hao-Wei LEE, I-Kang FU, Chun-Chia CHEN, Chen-I LIAO, Hung-Yu WEI
  • Patent number: 11891447
    Abstract: Methods for treating cancer and/or reducing sternness of cancer stem cells in a subject using a CD14 antagonist, which may be an anti-CD14 antibody.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: February 6, 2024
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventor: Huei-Wen Chen
  • Publication number: 20240040933
    Abstract: The present invention discloses a metal-free perovskite film and metal-free perovskite piezoelectric nanogenerators comprising the film. The metal-free perovskite film is organic, lead-free and metal-free. The open-circuit voltage of the metal-free perovskite piezoelectric nanogenerators can reach 9˜16 V and the short-circuit current of the metal-free perovskite piezoelectric nanogenerators can reach 38˜55 nA. Also, the metal-free perovskite piezoelectric nanogenerators can be used as self-powered strain sensor of human-machine interface application and be adopted in in vitro electrical stimulation devices.
    Type: Application
    Filed: November 29, 2022
    Publication date: February 1, 2024
    Applicants: NATIONAL CENTRAL UNIVERSITY, NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Po-Kang YANG, Meng-Lin TSAI, Han-Song WU, Shih-Min WEI, Shih-Min HUANG
  • Publication number: 20240032999
    Abstract: The present invention relates to a method and apparatus for non-invasive image-observing the density of an intra-epidermal nerve fiber of human skin, in which the method includes: providing a nonlinear optical microscopy device for capturing an intra-epidermal nerve fiber structural image of an acquisition area of a to-be-tested human skin to observe continuous signals of intra-epidermal nerve fiber images, wherein the nonlinear optical microscopy device includes: a laser light source for emitting laser light with a pulsed laser, and an image processing member for processing image signals; focusing the laser light on the intra-epidermal nerve fiber to obtain nerve signals of the intra-epidermal nerve fiber that have a length of at least three points of the intra-epidermal nerve fiber, and constitute a plurality of nerve fibers; and calculating the total number of nerve fiber signals of the to-be-tested human skin, and dividing it by the total area of captured images to obtain the density of the to-be-tested h
    Type: Application
    Filed: July 28, 2022
    Publication date: February 1, 2024
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: CHI-KUANG SUN, PEI-JHE WU, HSIAO-CHIEH TSENG