Patents Assigned to National Taiwan University
  • Patent number: 12291868
    Abstract: A retrofitting method for a beam with an opening is disclosed. The retrofitting method provides a hoop cooperated with an inclined stirrup to form a reinforcement set. The hoop is used to enclose the opening; and the reinforcement set may be selectively adjusted according to the distance between the edge of opening and a column face. The retrofitting method and reinforcement set are not only suitable for openings located in the non-plastic hinge zone of the beam, but also suitable for the openings located in the plastic hinge zone.
    Type: Grant
    Filed: August 31, 2022
    Date of Patent: May 6, 2025
    Assignee: NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chien-Kuo Chiu, Min-Yuan Cheng, Chieh-Tzu Chou
  • Publication number: 20250130211
    Abstract: A method of screening new psychoactive substance is provided, including providing a sample; placing the sample on chromatographic paper; ionizing the sample on the chromatographic paper by a direct analysis in real time (DART); performing a mass spectrometry analysis on the ionized sample to obtain a sample mass spectrum; and comparing a known standard mass spectrum with the sample mass spectrum, in which when a profile of the known standard mass spectrum is the same as a profile of the sample mass spectrum and the known standard mass spectrum is not exactly the same as the sample mass spectrum, the sample is determined to be the new psychoactive substance. A platform for screening new psychoactive substance is also provided to quickly screen out the new psychoactive substance.
    Type: Application
    Filed: February 8, 2024
    Publication date: April 24, 2025
    Applicant: National Taiwan University
    Inventors: Cheng-Chih Hsu, Wei-Hsin Hsu, Kai-Wen Cheng, Hsin-Bai Zou, Tzu-Hsuan Feng
  • Patent number: 12276029
    Abstract: Present invention is related to a metallic particle-deposition substrate having a metal substrate and multiple metallic particles attached thereon. The metallic particles are nano-particles with at least 90% of these nano-particles as single layer being evenly dispersed on the metal substrate. Each of the metallic particle is isolated without toughing or overlapping. The metal substrate has different material than the metallic particles in each preferred embodiment in the present invention. More preferably, at least 80% of the metallic particles have the distance between each metallic particle is at a range of 2-6 nm for better generation of hotspot effects. The present invention provides a fast production method for producing the substrate with heterogeneous interface. The metallic particles are evenly attached to the surface of the metal substrate to obtain better surface enhanced Raman effect as to apply for sensors in all kinds of field.
    Type: Grant
    Filed: May 11, 2022
    Date of Patent: April 15, 2025
    Assignee: National Taiwan University of Science and Technology
    Inventors: Bing-Joe Hwang, Wei-Nien Su, Meng-Che Tsai, Sheng-Chiang Yang
  • Publication number: 20250110133
    Abstract: Provided is a method for predicting drug efficacy of lung cancer, including providing a biological sample of a subject with lung cancer; analyzing an expression level of Leucine Zipper Down-regulated in Cancer 1; and predicting the drug efficacy based on the expression level of the Leucine Zipper Down-regulated in Cancer 1. Also provided is kit for predicting drug efficacy of lung cancer in a subject in need thereof, including an antibody against Leucine Zipper Down-regulated in Cancer 1 or a Leucine Zipper Down-regulated in Cancer 1-specific primer. Further provided is a method for treating lung cancer, including enhancing expression of Leucine Zipper Down-regulated in Cancer 1 encoded by Ldoc1 gene in a subject in need thereof.
    Type: Application
    Filed: September 26, 2024
    Publication date: April 3, 2025
    Applicants: National Health Research Institutes, National Taiwan University Hospital Hsin-Chu Branch
    Inventors: Chia-Huei Lee, Hsien-Neng Huang
  • Patent number: 12260320
    Abstract: A method is disclosed to dynamically design acceleration units of neural networks. The method comprises steps of generating plural circuit description files through a neural network model; reading a model weight of the neural network model to determine a model data format of the neural network model; selecting one circuit description file from the plural circuit description files according to the model data format, so that the chip is reconfigured according to the selected circuit description file to form an acceleration unit adapted to the model data format. The acceleration unit is suitable for running a data segmentation algorithm, which may accelerate the inference process of the neural network model. Through this method the chip may be dynamically reconfigured into an efficient acceleration unit for the different model data format, thereby speeding up the inference process of the neural network model.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: March 25, 2025
    Assignee: NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY
    Inventors: Shun-Feng Su, Meng-Wei Chang
  • Patent number: 12257812
    Abstract: The metallic crystal structures inspired edge-to-edge tessellations and a tessellation based lattice structures are disclosed. In accordance with an exemplary embodiment of the invention, basic unit lattice cells are stacked and connected to constitute a three-dimensional tessellations, wherein each of the basic unit lattice cells comprises a multiple flat connecting portions formed on a surface of the basic unit lattice cell and intersecting with a multiple of axes intersecting in a center of the basic unit lattice cell, and the flat connecting portions of one of the basic unit lattice cell is connected to the flat connecting portions of the adjacent basic unit lattice cell to constitute a connection structure of edge-to-edge tessellation. The formed tessellations are periodically tessellated in a design domain to form different tessellated lattice structures. The Functionally Tessellated (FT) lattice structures composed of different tessellations by interlocking into each other are also disclosed.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: March 25, 2025
    Assignee: National Taiwan University of Science and Technology
    Inventors: Chinmai Bhat, Ajeet Kumar, Jeng-Ywan Jeng
  • Patent number: 12247916
    Abstract: Provided is an identification method of plastic microparticles, including: performing an infrared analysis on plastic microparticles to identify whether the plastic microparticles include polyethylene terephthalate, polyethylene, polypropylene, or nylon 66, wherein the identification is to determine whether the plastic microparticles have a characteristic peak of each plastic, and the characteristic peak is selected from signals that do not overlap and interfere with each other in the infrared spectrum signals of each plastic.
    Type: Grant
    Filed: June 7, 2022
    Date of Patent: March 11, 2025
    Assignee: National Taiwan University
    Inventors: Chihhao Fan, Jhen-Nan Lin, Jun-Wei Li, Ya-Zhen Huang
  • Patent number: 12247908
    Abstract: A detection device and a detection method for distinguishing types of particles in an aqueous solution are provided. The detection device includes a detection chip, a signal source and a processing device. The detection chip includes a substrate, a coplanar waveguide transmission line and a super-hydrophobic film mask. When a to-be-detected aqueous solution that contains to-be-detected particles is provided on the detection chip, the super-hydrophobic film mask of the detection chip can confine the to-be-detected aqueous solution in a detection area. The processing device controls the signal source to provide detection microwave signals with different detection frequencies, simultaneously measures a first output signal and a second output signal at the different detection frequencies to generate a to-be-detected absorption spectrum, and compares the to-be-detected absorption spectrum with historical absorption spectra, so as to determine types of the to-be-detected particles.
    Type: Grant
    Filed: June 1, 2022
    Date of Patent: March 11, 2025
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Chi-Kuang Sun, Peng-Jui Wang
  • Publication number: 20250076301
    Abstract: Provided is a method of accurate and sensitive characterization and prognosis of prostate cancer in a subject. The method includes obtaining a biological sample from the subject and determining the level of identified biomarkers.
    Type: Application
    Filed: September 5, 2024
    Publication date: March 6, 2025
    Applicant: National Taiwan University
    Inventors: Yeong-Shiau PU, Chung-Hsin CHEN, Pei-Wen HSIAO, Ming-Shyue LEE, Hsiang-Po HUANG, Kai-Hsiung CHANG
  • Publication number: 20250079861
    Abstract: A method is to estimate the state of batteries by using a multi-level neural network formed with at least three neural networks. The method comprises steps of: extracting features from the charging and discharging data of a battery through a first-level neural network to form a first-stage output data, and inputting the first-stage output data into a second-level neural network; enhancing local features in the first-stage output data through the second-level neural network to form a second-stage output data; combining the first-stage output data with the second-stage output data to form a combination result to be input into a third-level neural network for data modeling, to generate a state estimation result of the battery. The present invention improves the accuracy of estimation for a flat zone in the charge/discharge curve of the battery, and quickly adjusts the multi-level neural network to achieve accurate estimation of different types of batteries.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 6, 2025
    Applicant: NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chang-Hua LIN, Jhih-Han DAI, Yi-Xin LIN
  • Patent number: 12228784
    Abstract: A protective assembly and an imaging equipment set are provided. The protective assembly is used to accommodate an imaging lens, and includes a housing, a transparent partition, and an adhesive member. The housing includes a tube body segment and a bottom segment that is connected to the tube body segment. A curved portion is formed on a periphery of the bottom segment, and an accommodating space is defined by the housing. The imaging lens is movably disposed in the accommodating space. An inner side of the curved portion has an inclined surface that is configured to abut against a shell of the imaging lens. The transparent partition is disposed on the bottom segment of the housing. The adhesive member has an outer surface that is sticky and an inner surface that is fixed onto a bottom surface of the housing.
    Type: Grant
    Filed: December 28, 2021
    Date of Patent: February 18, 2025
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Chi-Kuang Sun, Pei-Jhe Wu, Ying-Ting Huang, Hsiao-Chieh Tseng
  • Patent number: 12228718
    Abstract: A system for quantitative differential phase contrast microscopy with isotropic transfer function utilizes a modulation mechanism to create a detection light field having a radial or other axial orientation of optical intensity gradient or other distribution. A condenser generates an off-axis light field to project onto an object under examination, thereby generating an object light field, which is then guided to an image capturing device through an objective lens for capturing images. A differential phase contrast algorithm is applied to the images for obtaining a phase, thereby a depth information corresponding to the phase can be obtained to reconstruct the surface profile of the object.
    Type: Grant
    Filed: March 15, 2023
    Date of Patent: February 18, 2025
    Assignees: NATIONAL TAIWAN UNIVERSITY, YONGLIN HEALTHCARE FOUNDATION
    Inventors: Yuan Luo, Yu-Hsuan Chuang, Yu-Zi Lin
  • Patent number: 12227619
    Abstract: The present invention provides a polyimide-based copolymer and electronic component and field effect transistor comprising the same. The polyimide-based copolymer comprises a copolymer of dianhydride and heterocyclic diamine, wherein the heterocyclic diamine has two benzene rings, and there are two ether bonds, two thioether bonds, or one ether bond and one thioether bond between the two benzene rings. The novel polyimide-based copolymer of the invention has excellent thermal-mechanical stability, has potential application prospects, and can be used as a substrate for flexible electronics.
    Type: Grant
    Filed: June 11, 2021
    Date of Patent: February 18, 2025
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Wen-Chang Chen, Mitsuru Ueda, Chun-Kai Chen, Yan-Cheng Lin
  • Patent number: 12220436
    Abstract: An isolated bacterial strain of Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 deposited under the DSMZ Accession No. DSM 34213 is provided; a probiotic composition including an Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 and optionally, one or more additional probiotic organisms that enhance the probiotic activity of the Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 is also provided; and a method for preventing or treating chronic kidney disease in a subject in need thereof including: administering to the subject a pharmaceutically effective amount of the probiotic composition including an isolated bacterial strain of Lactiplantibacillus plantarum subsp. plantarum MFM 30-3, and optionally, one or more additional probiotic organisms that enhance the probiotic activity of the Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 is further provided.
    Type: Grant
    Filed: November 6, 2023
    Date of Patent: February 11, 2025
    Assignee: National Taiwan University
    Inventors: Ming-Ju Chen, Hsiao-Wen Huang
  • Patent number: 12220377
    Abstract: The present invention provides a portable guidance device for cardiopulmonary resuscitation, which comprises a tri-axial gravity sensing element, a pressure sensing element, a sound output element, a visual output element and a microcontroller. The portable guidance device for cardiopulmonary resuscitation can actively connect to the medical rescue system and issue an alarm to guide the surrounding passers-by to perform real-time rescue and perform correct cardiopulmonary resuscitation, so as to improve the efficiency and accuracy of chest compressions.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: February 11, 2025
    Assignees: NATIONAL TAIWAN UNIVERSITY HOSPITAL, FINE-I LTD.
    Inventors: Ting An Yen, Ching Chia Wang, Hwa Chang Wang
  • Patent number: 12217134
    Abstract: A quantum charge-coupled device including a first ion, a second ion, a fixed ion trap, an adjustable ion trap, and an excitation light source is provided. The fixed ion trap is configured to stationarily trap the first ion. The adjustable ion trap works as an ion rail disposed beside the fixed ion trap, wherein the ion rail is configured to make the second ion move at a constant velocity along the ion rail. The excitation light source is configured to irradiate an incident light beam. The incident light beam includes a series of light pulses and covers the first ion and the second ion when a distance between them becomes less than or equal to a proximity range, such that a quantum entangled state is directly built between the first ion and the second ion in uniform motion.
    Type: Grant
    Filed: November 24, 2022
    Date of Patent: February 4, 2025
    Assignee: National Taiwan University
    Inventors: Guin-Dar Lin, Wen-Han Png
  • Publication number: 20250032015
    Abstract: A blood physiological parameter sensing device includes a housing, a flow channel structure, a control unit and a sensing unit. The flow channel structure is disposed in the housing and forms a channel for a liquid to be measured to pass. The control unit is disposed in the housing. The sensing unit is disposed in the housing, is electrically connected to the control unit, and has a sensing end. The sensing end passes through the flow channel structure, is configured in the channel, and has an electrochemical sensing material. The electrochemical sensing material is used to exchange electrons with the blood physiological parameter in the liquid to be measured to produce redox reactions to generate current or voltage change parameters. The sensing unit transmits the current or voltage change parameters to the control unit, which obtains a blood physiological parameter concentration value to achieve instantaneous and continuous monitor the patients.
    Type: Application
    Filed: July 22, 2024
    Publication date: January 30, 2025
    Applicants: National Taiwan University, National Taiwan University Hospital Hsin-Chu Branch, National Yang Ming Chiao Tung University
    Inventors: Yih-Sharng CHEN, Hsiao-En TSAI, Yu-Ting CHENG
  • Patent number: 12208115
    Abstract: A pH-responsive hydrogel, which is synthesized by using mixed pectin and sucralfate treated with a small amount of acid to form a pH-responsive hydrogel. The pH-responsive hydrogel can form a temporary coating on the surface of the gastrointestinal tract to reduce excessive nutrient absorption, and exhibits excellent barrier properties and mucosal adhesion effects, which are useful for reducing blood sugar rise and weight gain, the liver fat accumulation, body fat accumulation and blood low-density lipoprotein that have a significant effect. In addition, the technical principles disclosed in the pH-responsive hydrogel should be applied to other polymer materials to manufacture different pH-responsive hydrogels.
    Type: Grant
    Filed: December 5, 2022
    Date of Patent: January 28, 2025
    Assignees: NATIONAL HEALTH RESEARCH INSTITUTES, NATIONAL TAIWAN UNIVERSITY
    Inventors: Feng-Huei Lin, Rui-Chian Tang, Tzu-Chien Chen
  • Publication number: 20250030162
    Abstract: The present invention is a reconfigurable antenna, which includes a total reflection part, a partial reflection part, a partial transmission part, and a radiation part stacked in sequence. A resonant cavity is formed between the partial reflection part and the total reflection part. The radiation part is arranged in the resonant cavity. So that the electromagnetic wave radiated by the radiation part is reflected in the resonant cavity. The electromagnetic wave forms constructive interference during the reflection of the resonant cavity. The resonant cavity makes the electromagnetic wave form the same phase electromagnetic wave and radiation penetrating the reflection part. The partial transmission part is regulated to form beam reconstruction conditions, and the same-phase electromagnetic waves are formed into beams and radiated into space by the beam control conditions.
    Type: Application
    Filed: July 19, 2023
    Publication date: January 23, 2025
    Applicant: National Taiwan University
    Inventors: Yi-Cheng LIN, Ching-Mei WANG, Chang-Kai LAI
  • Patent number: 12206148
    Abstract: The invention discloses a filter device. The filter device comprises a substrate, at least one transmission conductor, and a reference conductor having a slotted structure. The substrate is provided at a first surface thereof with the transmission conductor, and provided at a second surface thereof with the reference conductor. The slotted structure comprises a frame portion, a slotted portion, and a hollow portion. The slotted portion surrounds the frame portion, and the hollow portion is formed in the frame portion. At least one impedance unit is configured on the frame portion. The equivalent filter circuit of the filter device is formed between the transmission conductor, the slotted structure, the reference conductor, and the impedance unit. Thereby, the equivalent filter circuit absorbs at least one noise at at least one specific frequency by the impedance unit to avoid the noise reflected to affect the transmission quality of signal.
    Type: Grant
    Filed: December 10, 2021
    Date of Patent: January 21, 2025
    Assignee: National Taiwan University
    Inventors: Tzong-Lin Wu, Hsu-Wei Liu, Chi-Hsuan Cheng, Po-Jui Li