Abstract: An optical filter includes a first loop mirror, a second loop mirror, a first waveguide optically coupled to the first loop mirror and the second loop mirror, and a first access waveguide. The first loop mirror includes a first loop waveguide and a first multiplexer/demultiplexer. The second loop mirror includes a second loop waveguide and a second multiplexer/demultiplexer. The first loop waveguide is optically coupled to the first multiplexer/demultiplexer. The second loop waveguide is optically coupled to the second multiplexer/demultiplexer. The first waveguide is optically coupled to the first multiplexer/demultiplexer and the second multiplexer/demultiplexer. The first access waveguide is optically coupled to the first waveguide.
Type:
Application
Filed:
July 8, 2022
Publication date:
February 9, 2023
Applicants:
SUMITOMO ELECTRIC INDUSTRIES, LTD., NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: A spectral image capturing method using a spectral camera control device installed in aircraft, the method comprising: a) setting an exposure time of the spectral camera so that a current exposure time is determined (S2), b) determining whether or not either an amount of attitude change or an amount of position change of the spectral camera per exposure time exceeds a predetermined threshold based on a spatial resolution of the spectral camera (S4), c1) when exceeding the predetermined threshold, resetting the current exposure time to be shorter (S5), c2) when not exceeding the predetermined threshold, not resetting the current exposure time to be shorter, and d) capturing a spectral image in a snapshot mode with the spectral camera using the reset exposure time, wherein when the transmission wavelength of the liquid crystal tunable filter is switched while the aircraft is in a stationary flight, steps b) to d) are repeated.
Type:
Grant
Filed:
November 20, 2020
Date of Patent:
February 7, 2023
Assignee:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: This light absorbing device includes: a light reflecting layer; a dielectric layer disposed on the light reflecting layer; and a plurality of metal nanostructures disposed on the dielectric layer. A portion of each of the plurality of metal nanostructures is buried in the dielectric layer and another portion thereof is exposed to the outside.
Type:
Grant
Filed:
December 25, 2018
Date of Patent:
January 31, 2023
Assignee:
National University Corporation Hokkaido University
Abstract: A spectral camera control device, being installed, along with a spectral camera provided with a liquid crystal tunable filter, in an aircraft capable of stationary flight. The spectral camera control device causes the spectral camera to capture a spectral image in a snapshot mode each time a transmission wavelength of the liquid crystal tunable filter is switched while the aircraft is in stationary flight, and the spectral camera control device causes a plurality of spectral images to be captured in succession at a same transmission wavelength when an SN ratio of the captured spectral image is less than a predetermined threshold.
Type:
Grant
Filed:
November 20, 2020
Date of Patent:
January 3, 2023
Assignee:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: An object of the present invention is to provide cellulose acetate that has excellent compatibility with a resin, can reinforce a resin, and has excellent thermal stability. An embodiment of the present invention is cellulose acetate having a cellulose triacetate I crystal structure, wherein a temperature at which a weight loss relative to weight at 100° C. reaches 5% is 200° C. or higher when the cellulose acetate is heated at a heating rate of 10° C./min under a nitrogen atmosphere.
Type:
Grant
Filed:
June 12, 2019
Date of Patent:
December 13, 2022
Assignees:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, NIPPON PAPER INDUSTRIES CO., LTD., DAICEL CORPORATION
Inventors:
Yasumitsu Uraki, Haruo Konno, Shu Shimamoto
Abstract: The present invention provides a method for assessing the possibility of onset or progression of chronic kidney allograft rejection or chronic kidney disease in a test subject, by using, as an indicator, the level of SYT17 protein in a urine-derived specimen collected from the test subject. The present invention also provides: a pharmaceutical composition for preventing and/or treating chronic kidney allograft rejection or chronic kidney disease, the pharmaceutical composition including at least one substance selected from the group consisting of a specific antibody to SYT17, a derivative of the specific antibody, and an inhibitory nucleic acid against SYT17; and a test kit for use in assessing the possibility of onset or progression of chronic kidney allograft rejection or chronic kidney disease, the test kit including a specific antibody to SYT17 or a derivative of the specific antibody.
Type:
Application
Filed:
February 1, 2021
Publication date:
December 8, 2022
Applicant:
National University Corporation Hokkaido University
Abstract: The present invention relates to a method for screening an anticancer agent by causing drosophila having the characteristics of a) expression of mutant Ras85D, b) deletion or suppressed expression of a p53 gene, c) overexpression of a cyclin E gene, and d) deletion or suppressed expression of a Med gene to ingest a test substance and comparing the survival rate thereof with the survival rate of drosophila that did not ingest the test substance. The present invention also relates to a combination drug of at least two kinase inhibitors for treatment of pancreatic cancer and to kinase inhibitors for use in said combination drug.
Type:
Application
Filed:
March 1, 2021
Publication date:
December 8, 2022
Applicant:
National University Corporation Hokkaido University
Abstract: A lipid membrane structure includes, as lipid components, a lipid compound represented by Formula (I): (R1)(R2)C(OH)—(CH3)a—(O—CO)b—X??(I) [in the formula, a represents an integer of 3 to 5; b represents an integer of 0 or 1; R1 and R2 each independently represents a linear hydrocarbon group that may have —CO—O—; and X represents a 5- to 7-membered non-aromatic heterocyclic group or a group represented by Formula (B) (in the formula, d represents an integer of 0 to 3, and R3 and R4 each independently represents a C1-4 alkyl group or a C2-4 alkenyl group, where, R3 and R4 may be bonded to each other to form a 5- to 7-membered non-aromatic heterocycle (where, one or two C1-4 alkyl groups or C2-4 alkenyl groups may be substituted on the ring)].
Type:
Grant
Filed:
June 15, 2018
Date of Patent:
December 6, 2022
Assignee:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: A latent heat storage body microcapsule includes a core including gallium or gallium alloy; and a shell covering the core and including gallium oxide. A method for producing the same includes a particle-forming step of forming gallium or an alloy of gallium in a liquid state into particles; a water treatment step of heating the particles in distilled water to form a gallium hydrate on a surface of each of the particles; and an oxidation treatment step of oxidizing the gallium hydrate to form a shell including gallium oxide. The method includes a particle-forming step of forming gallium or an alloy of gallium in a liquid state into particles; a cooling step of cooling the particles to a solid state; and a pH treatment step of immersing the particles in an aqueous solution having a predetermined pH to form a shell including gallium hydrate.
Type:
Application
Filed:
August 27, 2020
Publication date:
December 1, 2022
Applicant:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: An object is to provide a composition and a method for eliminating undifferentiated pluripotent stem cells remaining in a cell group induced to differentiate from pluripotent stem cells. It has been found that while dihydroorotate dehydrogenase inhibitors exhibit cytotoxic activity against pluripotent stem cells, they do not exhibit significant cytotoxic activity against differentiated cells such as somatic stem cells.
Type:
Application
Filed:
December 19, 2019
Publication date:
November 17, 2022
Applicant:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: A rare earth complex including a rare earth ion and a ligand coordinated with the rare earth ion and having a condensed polycyclic aromatic group.
Type:
Grant
Filed:
February 22, 2018
Date of Patent:
November 15, 2022
Assignee:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: A quantum key distribution device is provided with an encoding unit which encodes an optical pulse train; an intensity modulating unit which subjects the encoded optical pulse train to N (where N is an integer at least equal to 3) types of intensity modulation having mutually different intensities, with different timings; and a first key distillation processing unit which generates an encryption key on the basis of a data sequence obtained by removing data obtained from an optical pulse having a specific modulation pattern from a data sequence used by the encoding unit and the intensity modulating unit.
Type:
Grant
Filed:
August 31, 2017
Date of Patent:
November 15, 2022
Assignees:
NEC CORPORATION, NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, National University Corporation Hokkaido University
Abstract: A balanced-lattice-ledge nucleant having ledge inducing local densification of proteins and a balanced-lattice inducing self-organized crystal packing. Using this balanced-lattice-ledge nucleant enhances nucleation of protein crystals.
Type:
Grant
Filed:
October 26, 2020
Date of Patent:
November 8, 2022
Assignee:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: The present invention provides a compound having antiviral activity, especially having arenavirus proliferation inhibitory activity, and/or a medicament comprising the compound. More preferably, the present invention provides a compound having proliferation inhibitory activity on the Old World arenaviruses such as Luna virus, Lassa virus, and lymphocytic choriomeningitis virus and/or the New World arenaviruses such as Junin virus, and/or a medicament comprising the compound.
Type:
Grant
Filed:
June 29, 2019
Date of Patent:
November 8, 2022
Assignees:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, SHIONOGI & CO., LTD.
Abstract: The hydrogel includes a first network structure and a second network structure. The second network structure is entwined with the first network structure. The first network structure contains a polymer crosslinked with a first crosslinking agent. The second network structure contains a polymer crosslinked with a second crosslinking agent. 50 mol % or more of the first crosslinking agent does not contain a decomposable bond. 50 mol % or more of the second crosslinking agent does not contain a decomposable bond.
Type:
Grant
Filed:
April 23, 2019
Date of Patent:
November 8, 2022
Assignees:
NGK SPARK PLUG CO., LTD., NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: A laminate which allows to obtain an organic thin-film solar cell having excellent output characteristics and transparency is provided. The laminate as above has a titanium oxide layer that is disposed on the member serving as a light-transmissive electrode layer and serves as an electron transport layer. The titanium oxide layer has a thickness of not less than 1.0 nm and not more than 200.0 nm. The titanium oxide layer contains indium oxide and metallic indium, InOx/Ti is not less than 0.50 and not more than 20.00 in atomic ratio, and InM/Ti is less than 0.100 in atomic ratio, where an elemental titanium content is represented by Ti, an indium oxide content is represented by InOx, and a metallic indium content is represented by InM.
Type:
Application
Filed:
September 28, 2020
Publication date:
October 20, 2022
Applicants:
JFE Steel Corporation, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: In order to provide an antibody having high therapeutic and prophylactic effects against cancer and the like, three types of mouse monoclonal antibodies were prepared which exhibit high affinities for a human-derived Eva1 protein. Moreover, constant regions of these antibodies were substituted with human-derived constant regions to also prepare chimeric antibodies. Further, these mouse antibodies and chimeric antibodies were found to have high ADCC and/or CDC activities. Furthermore, it was also revealed that administering these antibodies to mice having been subjected to melanoma cell administration suppresses the metastasis and the like of the cells to the lungs.
Type:
Application
Filed:
April 25, 2022
Publication date:
October 20, 2022
Applicant:
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Abstract: A heat-resistant alloy contains at least one element selected from a group consisting of Al, Ti, Ni, Cr, and Mo, O, and Y, and a ratio of a content of Y in terms of mass to a content of O in terms of mass is 0.5 or greater and 100 or less.
Type:
Application
Filed:
October 2, 2020
Publication date:
October 13, 2022
Applicants:
TOKYO METROPOLITAN PUBLIC UNIVERSITY CORPORATION, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Inventors:
Koji Kakehi, Shigenari Hayashi, Yen-Ling Kuo
Abstract: A composition for forming a phase-separated structure contains a block copolymer having a block (b1) consisting of a repeating structure of a styrene unit and a block (b2) consisting of a repeating structure of a methyl methacrylate unit, in which the block (b2) is disposed at least at one terminal portion of the block copolymer, the block copolymer has a structure (e1) represented by General Formula (e1) at least at one main chain terminal, and the structure (e1) is bonded to the main chain terminal of the block (b2) disposed at a terminal portion of the block copolymer. Ree0 represents a hydrocarbon group containing a hetero atom, and Re1 represents a hydrogen atom or a halogen atom.
Type:
Grant
Filed:
May 19, 2020
Date of Patent:
October 11, 2022
Assignees:
TOKYO OHKA KOGYO CO., LTD., NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
Inventors:
Ken Miyagi, Takahiro Dazai, Toshifumi Satoh, Takuya Isono