Patents Assigned to National University Corporation Nagoya University
  • Publication number: 20220259108
    Abstract: A method and apparatus for producing AlN whiskers includes reduced incorporation of metal particles, an AlN whisker body, AlN whiskers, a resin molded body, and a method for producing the resin molded body. The method for producing AlN whiskers includes heating an Al-containing material in a material accommodation unit to thereby generate Al gas; and introducing the Al gas into a reaction chamber through a communication portion while introducing nitrogen gas into the reaction chamber through a gas inlet port, to thereby grow AlN whiskers on the surface of an Al2O3 substrate placed in the reaction chamber.
    Type: Application
    Filed: May 2, 2022
    Publication date: August 18, 2022
    Applicant: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Toru UJIHARA, Yukihisa TAKEUCHI, Daishi SHIOJIRI, Masaki MATSUMOTO, Hiroshi SAITO, Ikuo HAYASHI
  • Patent number: 11415583
    Abstract: Provided are a method, an apparatus, and a kit for detecting a neuroblastoma in a subject and/or for monitoring a therapeutic effect on the neuroblastoma, by measuring a urinary tumor marker(s) in a sample from the subject.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: August 16, 2022
    Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, HITACHI, LTD.
    Inventors: Hiroo Uchida, Akinari Hinoki, Minoru Sakairi, Mayumi Abe
  • Patent number: 11377593
    Abstract: In a phosphor according to an aspect, an emission site has a perovskite crystal structure expressed by ABX3, in which A and B are each a cation and X is an anion, and an emission element is located at a B site serving as a body center of the perovskite crystal structure.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: July 5, 2022
    Assignees: KOITO MANUFACTURING CO., LTD., TOKYO INSTITUTE OF TECHNOLOGY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Hisayoshi Daicho, Yu Shinomiya, Kiminori Enomoto, Hideo Hosono, Satoru Matsuishi, Hiroshi Sawa, Akitoshi Nakano
  • Patent number: 11352408
    Abstract: Provide is an artificially synthesized antitumor peptide that may suppress proliferation of tumor cells. The peptide provided is a synthetic peptide that contains both (1) an amino acid sequence that forms a signal peptide of a membrane protein, programmed cell death-1 (PD-1), or a modified amino acid sequence thereof in which 1, 2 or 3 amino acid residues deleted from, substituted in or added to the above amino acid sequence; and (2) an amino acid sequence that serves as a cell penetrating peptide (CPP), and wherein the synthetic peptide comprises a total of 100 or fewer amino acid residues.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: June 7, 2022
    Assignees: Toagosei Co., Ltd., National University Corporation Nagoya University
    Inventors: Makoto Sawada, Nahoko Baileykobayashi, Tetsuhiko Yoshida
  • Patent number: 11345640
    Abstract: A method and apparatus for producing AlN whiskers includes reduced incorporation of metal particles, an AlN whisker body, AlN whiskers, a resin molded body, and a method for producing the resin molded body. The method for producing AlN whiskers includes heating an Al-containing material in a material accommodation unit to thereby generate Al gas; and introducing the Al gas into a reaction chamber through a communication portion while introducing nitrogen gas into the reaction chamber through a gas inlet port, to thereby grow AlN whiskers on the surface of an Al2O3 substrate placed in the reaction chamber.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: May 31, 2022
    Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Toru Ujihara, Yukihisa Takeuchi, Daishi Shiojiri, Masaki Matsumoto, Hiroshi Saito, Ikuo Hayashi
  • Patent number: 11344632
    Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: May 31, 2022
    Assignees: NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Katsunori Teranishi, Hitoshi Hirata, Tetsuya Arai
  • Patent number: 11339203
    Abstract: The antitumor peptide provided by the present invention is a synthetic peptide including both of: (1) an amino acid sequence composing the second transmembrane region from the N-terminal of a membrane protein sphingosine 1-phosphate receptor 1 (S1PR1), or a modified amino acid sequence formed by deletion substitution or addition of 1, 2 or 3 amino acid residues in the amino acid sequence; and (2) an amino acid sequence functioning as a cell-penetrating peptide (CPP); wherein the total number of amino acid residues is 100 or less.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: May 24, 2022
    Assignees: Toagosei Co., Ltd., National University Corporation Nagoya University
    Inventors: Nahoko Baileykobayashi, Tetsuhiko Yoshida, Makoto Sawada
  • Patent number: 11322764
    Abstract: A proton conducting film includes a polymer having a first part and a second part which are connected by a covalent bond and a plasticizer. The first parts aggregate with each other to form a domain at an operation temperature of the proton conducting film, and the second part crosslinks the domains. The second part has a proton accepting group, and the plasticizer contains a proton donating compound having a pKa of 2.5 or less, and thus the plasticizer penetrates into the second part, and a glass transition temperature of the polymer is lowered compared to when the plasticizer is not included.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: May 3, 2022
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Naoki Nakamura, Atsushi Noro, Takato Kajita, Haruka Tanaka, Yushu Matsushita
  • Patent number: 11313862
    Abstract: The method for aiding ALS detection provided by the present invention includes determining a profile of signal peptides contained in a bodily fluid from a test subject, and comparing the signal peptide profile thus determined for the test subject with a previously-determined profile of signal peptides in a bodily fluid from a healthy subject. The presence of a difference between the signal peptide profile of the test subject and the signal peptide profile of the healthy subject at a specific molecular weight is then associated with the test subject's suffering from or developing ALS.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: April 26, 2022
    Assignees: Toagosei Co., Ltd., National University Corporation Nagoya University
    Inventors: Nahoko Baileykobayashi, Makoto Sawada, Tetsuhiko Yoshida
  • Patent number: 11301785
    Abstract: An operating system for a vehicle-sharing service includes: a reservation input unit configured to input a usage reservation of an electric vehicle made by a user; a reservation result sending unit; a charging plan creating unit configured to create a charging plan for the electric vehicle; and a cost calculating unit configured to calculate an operation cost of the vehicle-sharing service based on a prediction of an available solar power supply. The charging plan creating unit creates the charging plan such that the operation cost of the vehicle-sharing service has a minimum cost under a predetermined acceptance condition. The result sending unit sends, to the user, a reservation result indicating that the usage reservation is unacceptable when the operation cost calculated according to the charging plan does not satisfy the predetermined acceptance condition.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: April 12, 2022
    Assignees: DENSO CORPORATION, National University Corporation Nagoya University
    Inventors: Akira Ito, Tatsuya Suzuki, Shinkichi Inagaki, Akihiko Kawashima
  • Patent number: 11299555
    Abstract: This method for aiding Alzheimer's detection provided by the present invention includes: determining a profile of signal peptides contained in a bodily fluid from a test subject, and comparing the signal peptide profile thus determined for the test subject with a previously-determined profile of signal peptides in a bodily fluid from a healthy subject. A difference between the signal peptide profile of the test subject and the signal peptide profile of the healthy subject at a specific molecular weight is then associated with the test subject's suffering from or developing Alzheimer's.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: April 12, 2022
    Assignees: Toagosei Co., LTD, National University Corporation Nagoya University
    Inventors: Nahoko Baileykobayashi, Makoto Sawada, Tetsuhiko Yoshida
  • Patent number: 11279037
    Abstract: A force-sense visualization apparatus includes a data acquisition unit configured to acquire image data and force-sense data, image data being obtained by taking an image of a surrounding environment of a robot, the force-sense data relating to a force sense that the robot has received from the outside, a conversion unit configured to convert the force sense into text information composed of onomatopoeia based on the force-sense data, and an image output unit configured to superimpose the text information on the image of the image data and output the resultant image data.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: March 22, 2022
    Assignees: National University Corporation Nagoya University, TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: Yasuhisa Hasegawa, Jun Nakanishi, Shunki Itadera, Jotaro Chiba, Fuminori Saito
  • Patent number: 11261091
    Abstract: A carbon nanosheet, which is a sheet-form carbon nanomaterial having a larger area as compared with that of a similar conventional product and a side length of about 1 ?m, and a method for producing the carbon nanosheet. The carbon nanosheet production method includes a step of mixing a solution of an iron atom-containing compound dispersed in a solvent with an alcohol, to thereby prepare a solution mixture; and a step of irradiating the solution mixture with plasma, to thereby produce a carbon nanosheet. The carbon nanosheet has a side length of 0.5 ?m to 2.5 ?m.
    Type: Grant
    Filed: December 25, 2018
    Date of Patent: March 1, 2022
    Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Masaru Hori, Hiroki Kondo, Kenji Ishikawa
  • Patent number: 11240969
    Abstract: A grafting apparatus includes plate-shaped grafting members each provided with, on a main surface on one side in a thickness direction thereof, at least one plant holder to hold a plant for grafting. The grafting apparatus includes a cutter and a joiner. The cutter is configured to cut a stem of the plant for grafting that is held by the at least one plant holder of each of the grafting members. The joiner is configured to mutually join at least parts of the grafting members, while the at least one plant holder holds a part of the plant for grafting that has been cut by the cutter, to thereby mutually join parts of the plants for grafting.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: February 8, 2022
    Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Michitaka Notaguchi, Kenji Tachibana, Ryusei Yamaguchi
  • Patent number: 11235536
    Abstract: A protrusion on a first member made of synthetic resin wherein a laser beam is applied to a side surface of the protrusion in a state in which a top surface of the protrusion of the first member is abutted against a second member made of synthetic resin, so as to melt at least the entire top surface of the protrusion and melt a portion of the second member in contact with the protrusion by heat of the melted top surface of the protrusion, followed by solidification of the melted portions, whereby the first member and the second member are welded together.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: February 1, 2022
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, ISHIKAWA PREFECTURE, TORAY INDUSTRIES, INC., MITSUBISHI JIDOSHA KOGYO KABUSHIKI KAISHA, SUZUKI MOTOR CORPORATION, TEIJIN LIMITED
    Inventors: Takayuki Mori, Kenichi Hirosaki, Wataru Okumura, Daisuke Mori, Yoshihiro Iwano, Kazuaki Amaoka
  • Patent number: 11236334
    Abstract: The present invention addresses the problem of providing a technique for more conveniently delivering a polynucleotide in a less cytotoxic form into a cell. This problem is solved by a polynucleotide modified by a molecule that contains a structure that contains a disulfide bond and/or a thiol group.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: February 1, 2022
    Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Hiroshi Abe, Zhaoma Shu
  • Patent number: 11225639
    Abstract: A cell sorting device is characterized by including: a main flow channel (14) through which a liquid containing a row of cells including a target cell flows, and in which a cell separation area for separating the target cell from the row of cells is provided at a halfway position in a flow direction, the main flow channel being formed in a substrate (12); a selection flow channel (16) into which the target cell is pushed out from the main flow channel, the selection flow channel being formed in the substrate so as to branch from the main flow channel downstream of the cell separation area; a sub flow channel (18) through which a separating liquid flows, the separating liquid being for separating the target cell from the row of cells and pushing out the target cell into the selection flow channel, the sub flow channel being formed in the substrate so as to intersect with the main flow channel in the cell separation area; a pair of liquid flow generating members (22) for generating a liquid flow of the separati
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: January 18, 2022
    Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Shinya Sakuma, Takeshi Hayakawa, Fumihito Arai
  • Patent number: 11203136
    Abstract: A method of producing thermoplastic resin composite material in which a main base material containing thermoplastic resin and a sheet-like shaped auxiliary base material are integrally molded and are made into composite material. The production method includes the steps of: heating the auxiliary base material (step S1); disposing the heated auxiliary base material in a mold (step S2); disposing the main base material in the mold via the auxiliary base material (step S3); closing the mold, and pressing together and integrally molding the auxiliary base material and the main base material (step S4); and taking out the integrally-molded thermoplastic resin composite material from the mold.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: December 21, 2021
    Assignees: HONDA MOTOR CO., LTD., SUBARU CORPORATION, SUZUKI MOTOR CORPORATION, TOYOTA JIDOSHA KABUSHIKI KAISHA, TEIJIN LIMITED, TORAY INDUSTRIES, INC., KYOWA INDUSTRIAL CO., LTD., NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Satoshi Hirawaki, Yasunari Kuratani, Masashi Horikawa, Tomomi Ichida, Kazuaki Amaoka, Takashi Kusaka, Yoshinori Yamamori, Kosuke Sakurai
  • Patent number: 11185814
    Abstract: The absorption agent of the present invention contains water, an amine compound, and an organic solvent, and a value obtained by subtracting a solubility parameter of the organic solvent from a solubility parameter of the amine compound is 1.1 (cal/cm3)1/2 or more and 4.2 (cal/cm3)1/2 or less. The method for separation and recovery of an acidic compound of the present invention includes the steps of: bringing a mixed gas containing an acidic compound into contact with an absorption agent containing water, an amine compound, and an organic solvent to absorb the acidic compound into the absorption agent; causing the absorption agent that has absorbed the acidic compound to be phase-separated into a first phase containing the acidic compound in a high content and a second phase containing the acidic compound in a low content; and heating the first phase to release the acidic compound from the first phase.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: November 30, 2021
    Assignees: KOBE STEEL, LTD., NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Akira Matsuoka, Akira Kishimoto, Hiroshi Machida, Hirotoshi Horizoe
  • Patent number: 11174389
    Abstract: A phosphole compound represented by the formula (wherein Ar1 and Ar2 are the same or different, and represent an optionally substituted aromatic hydrocarbon ring or an optionally substituted heteroaromatic ring; Ar3 represents a divalent ?-conjugated unit; R1 represents an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group, or an optionally substituted heteroaryl group; R2 and R3 are the same or different, and represent a hydrogen atom, an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group, or an optionally substituted heteroaryl group; and Z represents a reactive group) can provide a fluorescent dye capable of maintaining a high fluorescence quantum yield irrespective of solvent polarity, and providing an improved fluorescence quantum yield and light resistance even in environments containing large amounts of water.
    Type: Grant
    Filed: July 24, 2017
    Date of Patent: November 16, 2021
    Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
    Inventors: Shigehiro Yamaguchi, Aiko Naka, Masayasu Taki, Chenguang Wang