Abstract: The present invention provides a suppression type antisense oligonucleotide targeting TDP-43 mRNA, containing a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a nucleotide sequence shown in any of SEQ ID NOs: 2-4, and a promotion type antisense oligonucleotide targeting TDP-43 mRNA, containing a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a nucleotide sequence shown in SEQ ID NO: 5.

Abstract: In an on-vehicle system, on-vehicle device and gateway are connected via a first network, and the gateway and relay are connected via a second network. The relay performs open-close control of a gate, using a TAS standard of Ethernet TSN. The gateway receives first and second packets including given data, generates a third packet including the first and second packets, and sends the third packets at the transmission timing that is a timing the gate is placed in from closed state to open state to the relay. The relay receives the third packet from the gateway. The relay switches timing to transfer data, for each type of data, and transfer the third packet to the other relay, during a period in which the gate for the type of data is in an open state.

Abstract: Provided is a ternary or quaternary semiconductor nanoparticle that enables the band-edge emission and a less toxic composition. A semiconductor nanoparticle is provided that contains Ag, In, and S and has an average particle size of 50 nm or less, wherein the ratio of the number of atoms of Ag to the total number of atoms of Ag and In is 0.320 or more and 0.385 or less, the ratio of the number of atoms of S to the total number of atoms of Ag and In is 1.20 or more and 1.45 or less. The semiconductor nanoparticle is adapted to emit photoluminescence having a photoluminescence lifetime of 200 ns or less upon being irradiated with light having a wavelength in a range of 350 nm to 500 nm.

Abstract: A semiconductor nanoparticle includes a core and a shell covering a surface of the core. The shell has a larger bandgap energy than the core and is in heterojunction with the core. The semiconductor nanoparticle emits light when irradiated with light. The core is made of a semiconductor that contains M1, M2, and Z. M1 is at least one element selected from the group consisting of Ag, Cu, and Au. M2 is at least one element selected from the group consisting of Al, Ga, In and Tl. Z is at least one element selected from the group consisting of S, Se, and Te. The shell is made of a semiconductor that consists essentially of a Group 13 element and a Group 16 element.

Abstract: A semiconductor light emitting element is provided. The semiconductor light emitting element has a semiconductor stack, an n-side conductor layer, a p-side conductor layer, a dielectric multilayered film, an n-side reflective layer and a p-side reflective layer, disposed in that order. The n-side and p-side reflective layers contain Ag as a major component and contain particles of at least one selected from an oxide, a nitride, and a carbide.

Abstract: A laser device for laser resonance ionization includes a wavelength variable grating-type titanium-doped sapphire laser and includes a titanium (Ti) doped titanium sapphire crystal disposed within a resonator. The titanium sapphire crystal is fixedly disposed on a stage. The titanium-doped sapphire crystal can be moved in the optical axis direction by the stage, thereby changing the position of the titanium-doped sapphire crystal. The switching between the wideband mode and the high-output mode can be performed by changing the position of the titanium-doped sapphire crystal.

Abstract: The present invention addresses the problem of providing a laser microdissection apparatus having good operational efficiency. The laser microdissection apparatus, comprising sample movement means capable of retaining a slide, device movement means on which a device having a thermofusible film for transferring a sample can be mounted, a laser irradiation part for irradiating the sample with a dissection laser light, storage means for correlating and storing positional coordinates of the sample in the location irradiated by the dissection laser light and positional coordinates of the thermofusible film in a location where the collected sample is adhered, and a movement means drive control part for controlling driving of the sample movement means and the device movement means on the basis of the positional coordinates of the sample and the thermofusible film. The dissection laser light is radiated through the device onto the sample from below the device.

Abstract: A seedling nursery member for grafting according to an aspect of the present disclosure includes at least one seedling nursery unit. At least one seedling nursery unit includes a seed storage section configured to store a seed of a plant and have a space for the plant to germinate, a stem storage section configured to store a stem of the plant that has germinated and elongated, and a stem holder configured to hold the elongated stem of the plant. At least a portion of the seed storage section of at least one seedling nursery unit is configured to be openable to the outside of at least one seedling nursery unit. At least a portion of the stem storage section of at least one seedling nursery unit is configured to be openable to the outside of at least one seedling nursery unit.

Abstract: A laser therapeutic device for a laser endoscope capable of relatively reducing the diameter of the endoscope while being capable of emitting a laser beam of a uniform intensity over a wide area is provided. An optical guide element (a square-shaped rod lens 15, a guide tube 2b) having a quadrangular cross section and guiding a therapeutic laser beam emitted from the tip of an optical fiber toward the tip side of a probe is used. On the tip side of a probe tube 2 being a barrel, using clearances C1 to C4 formed between the optical guide element and the inner circumferential surface of the probe tube, a camera unit 11 as imaging means and white-color LED units 12 and an ultraviolet LED unit 13 as illumination means are arranged.

Abstract: A contact detection instrument including a rod, a tip sensor portion that is attached to one end of the rod and is inserted into a living body through a hole, a speaker that, from outside the living body, inputs a sound into a hollow space that is formed in the interior of the rod and the tip sensor portion, and a microphone that, outside the living body, outputs an electrical signal that corresponds to the sound inside the hollow space, with the tip sensor portion including an elastic material that covers the hollow space.

Abstract: A method and apparatus for producing AlN whiskers includes reduced incorporation of metal particles, an AlN whisker body, AlN whiskers, a resin molded body, and a method for producing the resin molded body. The method for producing AlN whiskers includes heating an Al-containing material in a material accommodation unit to thereby generate Al gas; and introducing the Al gas into a reaction chamber through a communication portion while introducing nitrogen gas into the reaction chamber through a gas inlet port, to thereby grow AlN whiskers on the surface of an Al2O3 substrate placed in the reaction chamber.

Abstract: A plasma treatment apparatus which performs uniform plasma treatment on a liquid. A plasma treatment apparatus includes a coaxial waveguide having an inner conductor, a first outer conductor, and a second outer conductor; a microwave generation unit; an outside tube which is located on the outer side of the first outer conductor and the second outer conductor and which in cooperation with the first outer conductor and the second outer conductor forms a flow path through which a liquid flows; and a plasma generation region. A first protrusion of the first outer conductor and a second protrusion of the second outer conductor face each other in a non-contacting state. The plasma generation region is a region extending along a facing location where the first protrusion of the first outer conductor and the second protrusion of the second outer conductor face each other.

Abstract: A virtual space display system for a self-driving moving body displays a virtual space different from a real environment such that a passenger on the moving body can enjoy the virtual space without feeling strange for a motion. The system includes a display device, a surrounding situation detector, and a virtual space display unit. The surrounding situation detector obtains information specifying features that influence a path along which the moving body is to move, and specifies such an important feature among features located in the surrounding of the moving body that presence/absence of the important feature has an influence on the path of the moving body. The virtual space display unit converts the important feature into an object that is fit for the influence on the path of the moving body based on a predetermined rule, and causes the display device to display the virtual space including the converted object.

Abstract: A gas treatment device uses a gas to be treated which contains an acid compound that dissolves into water to produce acid and a treatment liquid which absorbs the acid compound to phase-separate, to separate an acid compound from the gas to be treated. The gas treatment device includes an absorber which brings the gas to be treated into contact with the treatment liquid; a regenerator 14 which heats the treatment liquid contacting the gas to be treated to separate an acid compound; and a liquid feeding portion which feeds the treatment liquid contacting the gas to be treated in the absorber to the regenerator. In the absorber, the treatment liquid contacting the gas to be treated phase-separates into a first phase portion having a high acid compound content and a second phase portion having a low acid compound content. The liquid feeding portion is configured to introduce, into the regenerator, the treatment liquid with the phase-separated first phase portion and second phase portion mixed.

Abstract: A molecular beam epitaxy apparatus includes a radical generator for generating a radical species, a molecular beam cell for generating a molecular beam or an atomic beam, and a vacuum chamber for accommodating a substrate therein, in use, the substrate being irradiated with the radical species and the molecular beam or the atomic beam in vacuum, to thereby form, on the substrate, a crystal of a compound derived from the element of the radical species and the element of the molecular beam or the atomic beam.

Abstract: A main object of the present invention is to provide a block copolymer composition which has good elasticity, while having excellent stress relaxation properties. The object is achieved by providing a block copolymer composition obtained by a modification treatment, the block copolymer composition comprising a block copolymer B formed by introducing a functional group capable of forming a non-covalent bond into a block copolymer A including at least one aromatic vinyl polymer block and at least one conjugated diene polymer block.

Abstract: A semiconductor nanoparticle includes a core and a shell covering a surface of the core. The shell has a larger bandgap energy than the core and is in heterojunction with the core. The semiconductor nanoparticle emits light when irradiated with light. The core is made of a semiconductor that contains M1, M2, and Z. M1 is at least one element selected from the group consisting of Ag, Cu, and Au. M2 is at least one element selected from the group consisting of Al, Ga, In and Tl. Z is at least one element selected from the group consisting of S, Se, and Te. The shell is made of a semiconductor that consists essentially of a Group 13 element and a Group 16 element.

Abstract: A method and apparatus for analyzing carbon isotope 14C is provided. A carbon isotope analyzer including an isotopic carbon dioxide generator to generate isotopic carbon dioxide from a carbon isotope; a spectrometer including an optical resonator having a pair of mirrors, and a photodetector to determine the intensity of light transmitted from the optical resonator; and a light generator including a light source, a first optical fiber to transmit a light beam from the light source, a second optical fiber for wavelength conversion, the second optical fiber branching from the first optical fiber at a point and combining with the first optical fiber at another point downstream of the branching point, and a non-linear optical crystal to generate light having the absorption wavelength of the isotopic carbon dioxide on the basis of the difference in frequency between light beams transmitted through the optical crystal.

Abstract: An end mill machining apparatus, a CAM apparatus, an NC program, and a machining method which suppress regenerative self-excited vibration and mode-coupling self-excited vibration. An end mill machining apparatus includes an end mill, and a control section for controlling the end mill. The ratio of the protrusion length of the end mill to the diameter of the end mill falls within a range of 5 to 50. The end mill is a variable pitch, uniform helix type or a variable helix type. The control section controls the end mill such that the contact angle between the end mill and a workpiece M1 during machining becomes equal to or smaller than a critical contact angle ?lim.

Abstract: Provided is a ternary or quaternary semiconductor nanoparticle that enables the band-edge emission and a less toxic composition. A semiconductor nanoparticle is provided that contains Ag, In, and S and has an average particle size of 50 nm or less, wherein the ratio of the number of atoms of Ag to the total number of atoms of Ag and In is 0.320 or more and 0.385 or less, the ratio of the number of atoms of S to the total number of atoms of Ag and In is 1.20 or more and 1.45 or less. The semiconductor nanoparticle is adapted to emit photoluminescence having a photoluminescence lifetime of 200 ns or less upon being irradiated with light having a wavelength in a range of 350 nm to 500 nm.