Abstract: Provide is an artificially synthesized antitumor peptide that may suppress proliferation of tumor cells. The peptide provided is a synthetic peptide that contains both (1) an amino acid sequence that forms a signal peptide of a membrane protein, programmed cell death-1 (PD-1), or a modified amino acid sequence thereof in which 1, 2 or 3 amino acid residues deleted from, substituted in or added to the above amino acid sequence; and (2) an amino acid sequence that serves as a cell penetrating peptide (CPP), and wherein the synthetic peptide comprises a total of 100 or fewer amino acid residues.

Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.

Abstract: A method and apparatus for producing AlN whiskers includes reduced incorporation of metal particles, an AlN whisker body, AlN whiskers, a resin molded body, and a method for producing the resin molded body. The method for producing AlN whiskers includes heating an Al-containing material in a material accommodation unit to thereby generate Al gas; and introducing the Al gas into a reaction chamber through a communication portion while introducing nitrogen gas into the reaction chamber through a gas inlet port, to thereby grow AlN whiskers on the surface of an Al2O3 substrate placed in the reaction chamber.

Abstract: The antitumor peptide provided by the present invention is a synthetic peptide including both of: (1) an amino acid sequence composing the second transmembrane region from the N-terminal of a membrane protein sphingosine 1-phosphate receptor 1 (S1PR1), or a modified amino acid sequence formed by deletion substitution or addition of 1, 2 or 3 amino acid residues in the amino acid sequence; and (2) an amino acid sequence functioning as a cell-penetrating peptide (CPP); wherein the total number of amino acid residues is 100 or less.

Abstract: A proton conducting film includes a polymer having a first part and a second part which are connected by a covalent bond and a plasticizer. The first parts aggregate with each other to form a domain at an operation temperature of the proton conducting film, and the second part crosslinks the domains. The second part has a proton accepting group, and the plasticizer contains a proton donating compound having a pKa of 2.5 or less, and thus the plasticizer penetrates into the second part, and a glass transition temperature of the polymer is lowered compared to when the plasticizer is not included.

Abstract: The method for aiding ALS detection provided by the present invention includes determining a profile of signal peptides contained in a bodily fluid from a test subject, and comparing the signal peptide profile thus determined for the test subject with a previously-determined profile of signal peptides in a bodily fluid from a healthy subject. The presence of a difference between the signal peptide profile of the test subject and the signal peptide profile of the healthy subject at a specific molecular weight is then associated with the test subject's suffering from or developing ALS.

Abstract: This method for aiding Alzheimer's detection provided by the present invention includes: determining a profile of signal peptides contained in a bodily fluid from a test subject, and comparing the signal peptide profile thus determined for the test subject with a previously-determined profile of signal peptides in a bodily fluid from a healthy subject. A difference between the signal peptide profile of the test subject and the signal peptide profile of the healthy subject at a specific molecular weight is then associated with the test subject's suffering from or developing Alzheimer's.

Abstract: An operating system for a vehicle-sharing service includes: a reservation input unit configured to input a usage reservation of an electric vehicle made by a user; a reservation result sending unit; a charging plan creating unit configured to create a charging plan for the electric vehicle; and a cost calculating unit configured to calculate an operation cost of the vehicle-sharing service based on a prediction of an available solar power supply. The charging plan creating unit creates the charging plan such that the operation cost of the vehicle-sharing service has a minimum cost under a predetermined acceptance condition. The result sending unit sends, to the user, a reservation result indicating that the usage reservation is unacceptable when the operation cost calculated according to the charging plan does not satisfy the predetermined acceptance condition.

Abstract: A force-sense visualization apparatus includes a data acquisition unit configured to acquire image data and force-sense data, image data being obtained by taking an image of a surrounding environment of a robot, the force-sense data relating to a force sense that the robot has received from the outside, a conversion unit configured to convert the force sense into text information composed of onomatopoeia based on the force-sense data, and an image output unit configured to superimpose the text information on the image of the image data and output the resultant image data.

Abstract: A carbon nanosheet, which is a sheet-form carbon nanomaterial having a larger area as compared with that of a similar conventional product and a side length of about 1 ?m, and a method for producing the carbon nanosheet. The carbon nanosheet production method includes a step of mixing a solution of an iron atom-containing compound dispersed in a solvent with an alcohol, to thereby prepare a solution mixture; and a step of irradiating the solution mixture with plasma, to thereby produce a carbon nanosheet. The carbon nanosheet has a side length of 0.5 ?m to 2.5 ?m.

Abstract: A grafting apparatus includes plate-shaped grafting members each provided with, on a main surface on one side in a thickness direction thereof, at least one plant holder to hold a plant for grafting. The grafting apparatus includes a cutter and a joiner. The cutter is configured to cut a stem of the plant for grafting that is held by the at least one plant holder of each of the grafting members. The joiner is configured to mutually join at least parts of the grafting members, while the at least one plant holder holds a part of the plant for grafting that has been cut by the cutter, to thereby mutually join parts of the plants for grafting.

Abstract: A protrusion on a first member made of synthetic resin wherein a laser beam is applied to a side surface of the protrusion in a state in which a top surface of the protrusion of the first member is abutted against a second member made of synthetic resin, so as to melt at least the entire top surface of the protrusion and melt a portion of the second member in contact with the protrusion by heat of the melted top surface of the protrusion, followed by solidification of the melted portions, whereby the first member and the second member are welded together.

Abstract: The present invention addresses the problem of providing a technique for more conveniently delivering a polynucleotide in a less cytotoxic form into a cell. This problem is solved by a polynucleotide modified by a molecule that contains a structure that contains a disulfide bond and/or a thiol group.

Abstract: A cell sorting device is characterized by including: a main flow channel (14) through which a liquid containing a row of cells including a target cell flows, and in which a cell separation area for separating the target cell from the row of cells is provided at a halfway position in a flow direction, the main flow channel being formed in a substrate (12); a selection flow channel (16) into which the target cell is pushed out from the main flow channel, the selection flow channel being formed in the substrate so as to branch from the main flow channel downstream of the cell separation area; a sub flow channel (18) through which a separating liquid flows, the separating liquid being for separating the target cell from the row of cells and pushing out the target cell into the selection flow channel, the sub flow channel being formed in the substrate so as to intersect with the main flow channel in the cell separation area; a pair of liquid flow generating members (22) for generating a liquid flow of the separati

Abstract: A method of producing thermoplastic resin composite material in which a main base material containing thermoplastic resin and a sheet-like shaped auxiliary base material are integrally molded and are made into composite material. The production method includes the steps of: heating the auxiliary base material (step S1); disposing the heated auxiliary base material in a mold (step S2); disposing the main base material in the mold via the auxiliary base material (step S3); closing the mold, and pressing together and integrally molding the auxiliary base material and the main base material (step S4); and taking out the integrally-molded thermoplastic resin composite material from the mold.

Abstract: The absorption agent of the present invention contains water, an amine compound, and an organic solvent, and a value obtained by subtracting a solubility parameter of the organic solvent from a solubility parameter of the amine compound is 1.1 (cal/cm3)1/2 or more and 4.2 (cal/cm3)1/2 or less. The method for separation and recovery of an acidic compound of the present invention includes the steps of: bringing a mixed gas containing an acidic compound into contact with an absorption agent containing water, an amine compound, and an organic solvent to absorb the acidic compound into the absorption agent; causing the absorption agent that has absorbed the acidic compound to be phase-separated into a first phase containing the acidic compound in a high content and a second phase containing the acidic compound in a low content; and heating the first phase to release the acidic compound from the first phase.

Abstract: A phosphole compound represented by the formula (wherein Ar1 and Ar2 are the same or different, and represent an optionally substituted aromatic hydrocarbon ring or an optionally substituted heteroaromatic ring; Ar3 represents a divalent ?-conjugated unit; R1 represents an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group, or an optionally substituted heteroaryl group; R2 and R3 are the same or different, and represent a hydrogen atom, an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted aryl group, or an optionally substituted heteroaryl group; and Z represents a reactive group) can provide a fluorescent dye capable of maintaining a high fluorescence quantum yield irrespective of solvent polarity, and providing an improved fluorescence quantum yield and light resistance even in environments containing large amounts of water.

Abstract: In a method for analyzing samples involving the use of a device for analyzing samples, the device for analyzing samples includes at least a movement part through which a sample moves, and a measurement unit that is formed in a middle of the movement part and that measures a value of an ion current when the sample passes through the movement part. The analysis method includes at least a measurement step for measuring the value of the ion current when the sample passes through the movement part, and a determination step for determining a change over time in a quantity of ions from the value of the ion current measured in the measurement step. The quantity of ions includes a quantity of ions that have leaked from the sample during movement of the sample through the movement part.

Abstract: A seedling nursery member for grafting according to an aspect of the present disclosure includes at least one seedling nursery unit. At least one seedling nursery unit includes a stem storage section configured to store a stem of a plant and a stem holder configured to hold the stem of the plant. At least a portion of the stem storage section of the at least one seedling nursery unit is configured to be openable so as to allow communication between an inside of the stem storage section and an outside of the at least one seedling nursery unit in a direction different from a growth direction of the plant.

Abstract: Provided is a novel plant body comprising a plant tissue of a plant belonging to the family Solanaceae, Brassicaceae, Lamiaceae, or Orobanchaceae, wherein graft incompatibility is avoided or suppressed by using a graft medium between different-family plants.