Patents Assigned to New York University
  • Publication number: 20240113600
    Abstract: A synchronous generator can include a rotor. A three-phase high frequency alternating current source or a three-phase low frequency alternating current source can be in communication with the rotor.
    Type: Application
    Filed: October 5, 2023
    Publication date: April 4, 2024
    Applicant: New York University
    Inventor: Francisco De Leon
  • Publication number: 20240109953
    Abstract: The present disclosure provides polypeptides comprising an N-terminal portion(s) of Apolipoprotein B100 (ApoB100), or functional derivatives thereof, particularly polypeptides may be capable of, e.g., inhibiting scavenger receptor-B1 (SR-B1) and/or activin receptor-like kinase 1 (ALK1). Further provided are related polynucleotides, vectors, and pharmaceutical compositions. Methods for blocking endothelial cell uptake and/or transcytosis of lipoproteins comprising chylomicrons, low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), and/or lipoprotein (a) (Lp(a)) and treating atherosclerosis using the polypeptides and/or pharmaceutical compositions are also provided.
    Type: Application
    Filed: May 10, 2023
    Publication date: April 4, 2024
    Applicant: New York University
    Inventors: Ira J. Goldberg, Ainara González Cabodevilla, M. Mahmood Hussain
  • Patent number: 11946895
    Abstract: Principles for reliable manufacturing carbon-based electrodes with arbitrary sensitivity and homogeneity are provided. Specifically, the sensitivity of carbon-based electrodes can be engineered by changing the density of sp2 type defects present in a multilayer graphene film. The engineered carbon-based electrodes can be used as a passive sensing element in electrochemical measurement of a target analyte. Carbon-based electrodes are also disclosed that have sp2 hybridization and can include multilayer graphene films. The disclosed carbon-based electrodes have a density of zero-dimensional defects (i.e., point-like defects) which provides enhanced area-normalized sensitivity when used in sensing applications. The maximum area-normalized sensitivity is achieved at the point defect density of 4-5×1012 cm?2.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: April 2, 2024
    Assignee: NEW YORK UNIVERSITY
    Inventors: Davood Shahrjerdi, Roozbeh Kiani, Ting Wu
  • Patent number: 11944615
    Abstract: Provided are methods of sensitizing LKB1/STK11 deficient cancers to immune therapy. A method for treatment for LKB1/STK11 deficient cancers is provided comprising administration of inhibitor or inhibitors of one or more of NAMPT, CD38, SHP2, CXCR1/2, HDAC4 and PARP in combination with immunotherapy.
    Type: Grant
    Filed: September 3, 2021
    Date of Patent: April 2, 2024
    Assignee: New York University
    Inventors: David Peng, Kwok-Kin Wong, Jiehui Deng
  • Patent number: 11944608
    Abstract: Provided are methods for prophylaxis or therapy for an RNA virus infection. The methods involve modulating the Type I interferon pathway in RNA virus infected cells of an individual. The Type I interferon pathway is modulated by administering one or more agents to virus infected cells that inhibit the expression and/or function of METTL3 or inhibit expression and/or function of YTHDF1, YTHDF2 or YTHDF3.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: April 2, 2024
    Assignee: NEW YORK UNIVERSITY
    Inventors: Ian Mohr, Hannah Burgess, Angus Wilson
  • Patent number: 11944449
    Abstract: A method for assessing neurological function in a subject includes a) prompting a user to follow a moving saccade-evoking stimulus on a display, b) tracking eye movement of the subject while the user follows the moving stimulus, c) collecting a first eye conjugacy data of the subject relating to the saccade-evoking stimulus, and d) comparing the first eye conjugacy data with a second eye conjugacy data, the second eye conjugacy data relating to an anti-saccade stimulus.
    Type: Grant
    Filed: February 10, 2023
    Date of Patent: April 2, 2024
    Assignee: NEW YORK UNIVERSITY
    Inventor: Uzma Samadani
  • Patent number: 11948302
    Abstract: An in-line holographic microscope can be used to analyze a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. An assay using the holographic microscope for holographic particle characterization directly detect viruses, antibodies and related targets binding to the surfaces of specifically functionalized micrometer-scale colloidal probe beads. The system detects binding of targets by directly measuring associated changes in the bead's diameter without the need for downstream labeling and analysis.
    Type: Grant
    Filed: March 9, 2021
    Date of Patent: April 2, 2024
    Assignees: New York University, Spheryx, Inc
    Inventors: David G. Grier, Fook Chiong Cheong, Kaitlynn Snyder, Rushna Quddus, Lauren E. Altman, Kent Kirshenbaum
  • Patent number: 11938423
    Abstract: The present invention provides a system and methods for filtering fluid using filter papers, stationary paper, cloth sheets or any other porous material. In one embodiment, the present invention uses the lateral flow direction along the porous sheets, instead of conventional vertical flow direction, for the removal of bacteria and particle contamination in the range from nanometers to millimeters. The pore sizes in the filter media along the lateral direction are modulated by controlling the compression of the porous sheets, instead of conventionally designing filters with different pore sizes. The lateral flow fluid filter system is scalable simply by increasing the feed area, feed length, and the number of porous sheets. The invention presents a universal fluid filtration system for wide range of applications such as water purification, food processing, chemical industry, oil and gas industry, and biological applications.
    Type: Grant
    Filed: October 15, 2021
    Date of Patent: March 26, 2024
    Assignee: NEW YORK UNIVERSITY IN ABU DHABI CORPORATION
    Inventors: Sunil Kumar, Nityanand Kumawat, Mohammad A. Qasaimeh
  • Patent number: 11932683
    Abstract: The present invention relates to methods for treating and preventing Staphylococcus aureus infection and/or a condition resulting from a S. aureus infection in a subject that involves administering compositions that inhibit S. aureus interaction with CXCR1/CXCR2 and DARC cellular receptors. The present invention further relates to novel compositions for carrying out these and other methods.
    Type: Grant
    Filed: September 14, 2022
    Date of Patent: March 19, 2024
    Assignee: NEW YORK UNIVERSITY
    Inventors: Victor J. Torres, Tamara Reyes-Robles, Francis Alonzo
  • Publication number: 20240086684
    Abstract: An electronic device includes one or more processors and a memory storing instructions configured to, when executed by the one or more processors, cause the one or more processors to: implement a machine learning-based conditional generative model configured to reconstruct target data from latent vectors, the conditional generative model trained based on an existing data set for a target task; determine an extrapolation weight; generate an augmented latent vector and augmented condition data by extrapolating, based on the extrapolation weight, from a latent vector corresponding to the existing dataset and from existing condition data corresponding to the existing dataset; and generate a new dataset comprising augmented target data generated by the conditional generative model based on the augmented condition data and based on the augmented latent vector.
    Type: Application
    Filed: September 14, 2023
    Publication date: March 14, 2024
    Applicants: Samsung Electronics Co., Ltd., NEW YORK UNIVERSITY
    Inventors: Ki Soo KWON, Kyunghyun CHO, Hoshik LEE
  • Patent number: 11921023
    Abstract: Holographic Video Microscopy analysis of non-spherical particles is disclosed herein. Properties of the particles are determined by application of light scattering theory to holography data. Effective sphere theory is applied to provide information regarding the reflective index of a sphere that includes a target particle. Known particles may be co-dispersed with unknown particles in a medium and the holographic video microscopy is used to determine properties, such as porosity, of the unknown particles.
    Type: Grant
    Filed: December 30, 2022
    Date of Patent: March 5, 2024
    Assignees: New York University, Spheryx, Inc.
    Inventors: David G. Grier, Mary Ann Odete, Fook Chiong Cheong, Annemarie Winters, Jesse J. Elliott, Laura A. Philips
  • Patent number: 11921067
    Abstract: A method of diagnosing a conducting structure includes providing the conducting structure in a magnetic field, immersing the conducting structure in a detection medium, or placing a detection medium in the vicinity of the conducting structure, exciting nuclear or electronic spins within the detection medium using a broad-band excitation pulse, receiving an NMR or ESR spectrum from the detection medium, obtaining a frequency distribution of the detection medium, and indirectly measuring internal characteristics of the conducting structure by characterizing frequency changes in the frequency distribution. Conducting structures are analyzed on the basis of changes in magnetic susceptibilities and internal electric current distributions, which may change over the course of a charging/discharging cycle, and a result of degradation and failure of the conducting structure. The conducting structure may be, for example, a battery, a capacitor, a supercapacitor, a fuel cell, or a catalyst material.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: March 5, 2024
    Assignee: New York University
    Inventors: Alexej Jerschow, Andrew J. Ilott, Mohaddese Mohammadi, Emilia Silletta, Konstantin Romanenko
  • Patent number: 11918190
    Abstract: The present invention relates to expandable sleeves, expandable sleeve systems, and their methods of use. In certain aspects, the expandable sleeves are compatible with commonly used speculums to enhance visualization and access of an orifice. The expandable sleeves sheathe over the blades of a speculum and form a taut barrier when the blades are opened to hold back the walls of a tissue orifice and cavity. The expandable sleeves include inflatable pouches that further push back the walls of the orifice. In certain aspects, the expandable sleeves are useful in performing pelvic exams, such as in patients having lax vaginal walls or excess surrounding tissue.
    Type: Grant
    Filed: June 8, 2022
    Date of Patent: March 5, 2024
    Assignee: NEW YORK UNIVERSITY
    Inventor: Jacqueline F. Ford
  • Patent number: 11908194
    Abstract: A modular tracking system is described comprising of the network of independent tracking units optionally accompanied by a LIDAR scanner and/or (one or more) elevated cameras. Tracking units are combining panoramic and zoomed cameras to imitate the working principle of the human eye. Markerless computer vision algorithms are executed directly on the units and provide feedback to motorized mirror placed in front of the zoomed camera to keep tracked objects/people in its field of view. Microphones are used to detect and localize sound events. Inference from different sensor is fused in real time to reconstruct high-level events and full skeleton representation for each participant.
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: February 20, 2024
    Assignee: New York University
    Inventors: Yurii S. Piadyk, Carlos Augusto Dietrich, Claudio T Silva
  • Patent number: 11903330
    Abstract: The method of performing braiding operations can include providing a first Josephson junction including first gates. The method can include providing a second Josephson junction including second gates. The method can include tuning the first gates to dispose a first pair of Majorana fermions a first region. The method can include tuning the second gates to dispose a second pair of Majorana fermions in a second region. The method can include tuning the first gates to dispose a first Majorana fermion in the first region and to dispose a second Majorana fermion in a third region. The method can include tuning the second gates to dispose a third Majorana fermion in a fourth region and to dispose a fourth Majorana fermion in the second region.
    Type: Grant
    Filed: July 16, 2021
    Date of Patent: February 13, 2024
    Assignee: NEW YORK UNIVERSITY
    Inventors: Javad Shabani, Matthieu C. Dartiailh
  • Patent number: 11897921
    Abstract: The present invention is directed to a fusion protein comprising a light chain region of a Clostridial neurotoxin and a heavy chain region of a Clostridial neurotoxin, where the light and heavy chain regions are linked by a disulfide bond. The fusion protein also has a single chain antibody positioned upstream of the light chain region, where the single chain antibody possesses antigen-binding activity. Also disclosed are therapeutic agents, treatment methods, propeptide fusions, isolated nucleic acid molecules, expression systems, host cells, and methods of expressing fusion proteins.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: February 13, 2024
    Assignee: NEW YORK UNIVERSITY
    Inventors: Konstantin Ichtchenko, Edwin Vazquez-Cintron, Philip A. Band, Timothy J. Cardozo
  • Publication number: 20240045966
    Abstract: An aspect of behavior of an embedded system may be determined by (a) determining a baseline behavior of the embedded system from a sequence of patterns in real-time digital measurements extracted from the embedded system; (b) extracting, while the embedded system is operating, real-time digital measurements from the embedded system; (c) extracting features from the real-time digital measurements extracted from the embedded system while the embedded system was operating; and (d) determining the aspect of the behavior of the embedded system by analyzing the extracted features with respect to features of the baseline behavior determined.
    Type: Application
    Filed: July 21, 2023
    Publication date: February 8, 2024
    Applicant: NEW YORK UNIVERSITY
    Inventors: Farshad Khorrami, Ramesh Karri, Prashanth Krishnamurthy
  • Patent number: 11892449
    Abstract: Provided is a multivalent protein that targets interaction of SARS-CoV-2 spike receptor binding domain (RBD) with the human angiotensin-converting enzyme 2 (ACE2) receptor protein. The multivalent proteins may also be used to treat subjects having cancer and/or a disease and/or viral infection. Also presented is a multiplex lateral flow test strips for simultaneous detection of the virus and viral antibodies.
    Type: Grant
    Filed: November 23, 2022
    Date of Patent: February 6, 2024
    Assignee: New York University
    Inventors: Jin Kim Montclare, Farbod Mahmoudinobar, Kamia Punia, Dustin Robert Britton
  • Patent number: 11891422
    Abstract: This invention relates to macrostructures (and pharmaceutical formulations containing them) that include a parallel coiled-coil structure, wherein the parallel coiled-coil comprises a first coil of Formula I and a second coil of Formula II: T1-f0-g0-a1-b1-c1-d1-e1-f1-g1-a2-b2-c2-d2-e2-f2-g2-a3-b3-c3-d3-e3-T2??(I) T3-g?0-a?1-b?1-c?1-d?1-e?1-f?1-g?1-a?2-b?2-c?2-d?2-e?2-f?2-g?2-a?3-b?3-c?3-d?3-e?3-f?3-T4??(II), as described in the present application. Methods of using these macrostructures are also disclosed.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: February 6, 2024
    Assignee: NEW YORK UNIVERSITY
    Inventors: Paramjit S. Arora, Michael G. Wuo
  • Patent number: 11892390
    Abstract: An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: February 6, 2024
    Assignee: New York University
    Inventors: David G. Grier, Fook Chiong Cheong, Ke Xiao