Abstract: A multi-night titration (MNT) process to find an optimal single therapeutic pressure of a CPAP device. This single therapeutic pressure can then be used on an on-going basis by the patient after the titration period. The MNT process differs from current auto adjusting processes used for titration (or ongoing use) in that the MNT process does not respond locally by adjusting pressures to individual events. With existing devices, the continuous adjustment of supplied air pressure always responds to one or a small number of events and thus fails to compensate for a patient's adaptation thereto, resulting in the supply of a less than optimal therapeutic pressure to the patient. While auto adjusting processes often capture and respond well to short-term and transient conditions, the MNT process of the current disclosure seeks to capture long term trends and find the most suitable average single pressure for a patient.

Abstract: Exemplary embodiments include a computer-implemented method for configuring at least one antenna array comprising receiving a plurality of sets of samples corresponding to signals incident on a plurality of antennas; computing a mean of the envelopes of the sums of the respective sets; estimating a direction of arrival of the signals incident on the antennas based on the computed means; and configuring the antenna array based on the estimated direction of arrival. The computing and estimating procedures can be performed for each of a plurality of direction-of-arrival candidates. The estimating procedure can comprise determining a maximum value of the mean and a direction of arrival corresponding to the maximum value. The spatial selectivity of the antenna array can be configured based on the estimated direction of arrival. Other exemplary embodiments can include communication apparatus and computer-readable media embodying one or more of the exemplary computer-implemented methods and/or procedures.

Abstract: A system and method for improving intelligibility of speech is provided. The system and method may include obtaining an input audio signal frame, classifying the input audio signal frame into a first category or a second category, wherein the first category corresponds to the noise being stronger than the speech signal, and the second category corresponds to the speech signal being stronger than the noise, decomposing the input audio signal frame into a plurality of sub-band components; de-noising each sub-band component of the input audio signal frame in parallel by applying a first wavelet de-noising method including a first wavelet transform and a predetermined threshold for the sub-band component, and a second wavelet de-noising method including a second wavelet transform and the predetermined threshold for the sub-band component, wherein the predetermined threshold for each sub-band component is based on at least one previous noise-dominant signal frame received by the receiving arrangement.

Abstract: Disclosed herein are isolated and purified Staphylococcus aureus bi-component leukocidin, referred to herein as LukAB, and its components LukA and LukB, antibodies specific to LukA, antibodies specific to LukB, therapeutic compositions containing LukA and/or LukB, or anti-LukA and/or anti-LukB antibodies, uses of the compositions to treat acute inflammatory conditions or S. aureus infection, methods for identifying inhibitors of LukAB-mediated cytotoxicity of human phagocytes, and methods for using LukAB as a marker to predict severity of S. aureus infection.

Abstract: A system and method for in vivo detection and quantification of drusen present in the retina via administering an excitation signal to the retina of the eye and detecting an electromagnetic emissions spectrum from the retina in response to the excitation signal. The electromagnetic emissions spectrum may be used to identify a plurality of component emissions spectra, each component emissions spectrum corresponding to fluorescence from a component of the retina, one of the component emissions spectra corresponding to a target emissions spectrum.

Abstract: The invention relates to therapeutic and cosmetic uses of calreticulin including reducing or eliminating wrinkles and/or fine lines, tissue repair and reconstruction, repairing damaged bone and/or cartilage, stimulating regeneration of an epidermal appendage, enhancing phagocytosis of bacteria by phagocytes within a wound, treating a wound in a patient suffering from delayed wound healing, treating a corneal wound, and treating or preventing a surgical adhesion.

Abstract: Exemplary system, method and computer-accessible medium for determining a difference(s) between two sets of subjects, can be provided. Using such exemplary system, method and computer-accessible medium, it is possible to receive first imaging information related to a first set of subjects of the two sets of the subjects, receive second imaging information related to a second set of subjects of the two sets of subjects, generate third information by performing a decomposition procedure(s) on the first imaging information and the second information, and determine the difference(s) based on the third information.

Abstract: A sensor having a set of plates that are in contact from their bottom at the corners with a set of protrusions that are in contact from above with a plurality of intersections, each having a sensing element, of a grid of wires disposed on a base, and a top surface layer that is disposed atop the set of plates, so that force imparted from above onto the top surface layer is transmitted to the plates and then to the protrusions, and then to the intersections of the grid of wires which are thereby compressed between the base and protrusions; and that the protrusions above thereby focus the imparted force directly onto the intersections. A sensor includes a computer in communication with the grid which causes prompting signals to be sent to the grid and reconstructs a continuous position of force on the surface from interpolation based on data signals received from the grid. A method for sensing.

Abstract: Provided are methods and kits for reducing the severity of muscle stiffness. The method comprises delivering to one or more specific locations in the deep fascia of an affected muscle a composition comprising a therapeutically effective amount of hyaluronidase.

Abstract: In a magnetic resonance (MR) apparatus, and model-based method, for identifying a nuclear spin-dependent attribute of a subject, MR signals are acquired in multiple repetitions of an MR data acquisition sequence that is changed from repetition-to-repetition so as to deliberately encode effects of magnetization transfer between nuclear spins into the acquired MR signals. A model is generated, composed of at least two molecule pools, in which a single magnetization transfer parameter is used that is derived from the MR signals in which the magnetization transfer is encoded. A nuclear spin-dependent attribute of the subject is then identified, by comparing at least one MR signal evolution from the subject to at least one signal evolution produced by the model.

Abstract: The present invention relates to methods for treating and preventing Staphylococcus aureus infection and/or a condition resulting from a S. aureus infection in a subject that involves administering compositions that inhibit S. aureus interaction with CXCR1/CXCR2 and DARC cellular receptors. The present invention further relates to novel compositions for carrying out these and other methods.

Abstract: Treatment of neurological injury through motor relearning. A game-based sensorimotor rehabilitator that enables individuals to interact with the functional objects using the appropriate amount of force, tilt, finger movement, and muscle activity to regain lost skill due to injury.

Abstract: The invention provides methods and kits for detecting, screening, quantifying or localizing the etiology for reduced or impaired cranial nerve function or conduction or associated cranial nucleus or supranuclear input, useful for detecting, diagnosing or screening for increased intracranial pressure, or useful for detecting, diagnosing, monitoring progression of or screening for a disease or condition featuring increased intracranial pressure by tracking eye movement of the subject. The methods may be performed by a) analyzing eye movement of the subject; b) comparing eye movement of the subject to eye movement of a control or the subject's own baseline eye movement; and c) identifying the subject as having eye movement significantly different from the control or the subject's own baseline eye movement.

Abstract: An exemplary system for wrapping an intellectual property core (IP) bus master(s), can include, for example, a plurality of IP cores associated with the IP core bus master(s), and a wrapper module connected to a serial input of the IP core bus master(s) and a serial output of the IP core bus master(s), where the wrapper module can be configured to capture and shift a plurality of values of a system bus for a plurality of bus transfers associated with the IP core bus master(s) and the IP cores. The wrapper module can be further configured to modify a wrapper control logic and a wrapper boundary register of the IP core bus master(s). A plurality of terminals can be included, which can be coupled to the IP core bus master(s), and a plurality of wrapper cells can be included, which can be associated with the plurality of terminals.

Abstract: Provided are methods and devices for detection of unlabeled nucleic acids. The detection methods are based on change of solubility of hydrophobic probes upon hybridization with a polynucleotide. In one embodiment, the probes are morpholino probes, having a fluorophore attached thereto. The morpholino probes are immobilized on a substrate that has fluorescence quenching functionality.

Abstract: A method and a device are provided that improve quantification of the spin-spin relaxation (“T2”) time of an image in nuclear magnetic resonance (“NMR”) applications using fast multi spin-echo sequences. The method employs time-efficient computer simulations for exact modeling of spurious stimulated echoes in multi-dimensional magnetic resonance imaging (“MRI”) runs. The method employs Bloch simulations and can use a plurality of parameters to produce echo modulation curves prior to correcting distorted experimental data based on pre-calculated simulation values.

Abstract: Exemplary systems and methods can be provided for measuring a parameter—e.g., channel impulse response and/or power delay profile—of a wideband, millimeter-wave (mmW) channel. The exemplary systems can include a receiver configured to receive a first signal from the channel, generate a second signal, and measure the parameter based on a comparison between the first and second signals; and a controller configured to determine first and second calibration of the system before and after measuring the parameter, and determine a correction for the parameter measurement based on the first and second calibrations. Exemplary methods can also be provided for calibrating a system for measuring the channel parameter. Such methods can be utilized for systems in which the TX and RX devices share a common frequency source and for systems in which the TX and RX devices have individual frequency sources that free-run during channel measurements.

Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.

Abstract: The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated antibodies that recognize a common conformational epitope of amyloidogenic proteins or peptides that are useful for the diagnosis, treatment, and prevention of amyloid disease.

Abstract: The present invention provides methods of treating humans and animals with terpenes and terpenoids in order to restore the stratum granulosum and stratum corneum and treat a dermatological disease, such as, for instance atopic dermatitis. More specifically it provides terpenes and terpenoids such as monoterpenoids, sesquiterpenes and norisoprenoids as ingredients that work to restore and thicken the stratum granulosum and stratum corneum and treat a dermatological disease. Terpenes and terpenoid compounds support the cell proliferation, cell differentiation, growth of skin, skin tissue and keratinocytes by upregulating genes for loricrin filaggrin, caspase 14, hornerin and other late cornified envelope components and vascular endothelial growth factor (VEGF) and downregulation of matrix metalloproteinases. Both terpenes and terpenoids may be applied topically or orally at oral or topical concentrations from about 0.