Abstract: An adhesive tape comprising a water impermeable, gas permeable tape substrate, a pressure-sensitive adhesive layer provided on one side of the tape substrate, and a porous sheet provided on a portion of the pressure-sensitive adhesive layer, the porous sheet being capable of expanding to have an apparent density of 0.01 to 0.20 g/cm.sup.3 when absorbing water to saturation. The adhesive tape prevents the accumulation of perspiration between the adhesive tape and the skin of a user on which the adhesive tape is being applied and, hence, is not readily peeled off from the skin. The porous sheet expands upon absorbing blood from a wound to press against the wound, resulting in an enhanced hemostasis effect.

Abstract: A trocar assembly includes a cannula, a trocar needle fitted in a lumen of the cannula, a cannula-retaining member having a through-hole for inserting the cannula therein and being provided at a bottom thereof with an adhesive layer for fixing the cannula in place on the skin of a patient. The cannula is adapted to be held in the retaining member by engaging elements between them to permit the cannula to move forward continuously or continually through the through-hole of the retaining member as well as to fix the cannula in a desired position.

Abstract: An apparatus for dosing a liquid medicine has a balloon (1), a housing (3) and a delivery assembly `b`. The balloon receives and discharges a liquid medicine under pressure. The housing enclosing the balloon has an opening communicating with the assembly `b` in which a flow regulator (10) is installed. The balloon (1) is composed of flat and expansible sheets secured to both side rims of a short cylindrical frame (2). The flat sheets constituting the balloon are of an even thickness over their whole area, even after being inflated with the medicine, so that the pressure as well as the flow rate of the medicine effluent from the balloon will scarcely vary at the mouth over the course of time. Thus, the liquid medicine is dosed to a patient at a constant flow rate through the regulator.

Abstract: A rubber stopper for a vial comprising a body member 1 and a sheet of polyethylene 3 having an average molecular weight of 1,300,000 to 8,000,000, a surface being contacted with an inner surface of a mouth and a liquid medicine, or a top surface 1b of which is covered. The molecular chains of polyethylene are partially ramified by heat to be branched and partially crosslinked with a rubber of the body. Therefore, adhesion of them is high and a smoothness of the surface of the sheet portion is improved.

Abstract: A blood separating composition for use in blood collection tubes, the composition having an absolute viscosity of 100,000-320,000 cP at 25.degree. C. at a shear rate of 1 sec.sup.-1 when the blood separating composition turns into its dynamic state from its stationary state, with a reduced viscosity of 50,000 cP or more at a shear rate of 10 sec.sup.-1 in the dynamic state. The absolute viscosity of said composition is 100,000-300,000 cP at the shear rate of 1 sec.sup.-1 when returning to the stationary state. Such a viscosity renders stable and less flowable and blood separating composition during storage, allowing it to form a stable partition barrier in each collection tube when centrifuged to separate the blood phases one from another, with the blood cells above the barrier being prevented from remaining within the serum. The blood separating composition does not release any harmful oily substance or the like.

Abstract: An apparatus for dosing a liquid medicine. The apparatus includes a balloon having openings through which the medicine is charged and discharged; a housing holding the balloon and having an outlet adjacent to one of the openings; and a delivery assembly extending from the outlet. The balloon is composed of an inner layer, an outer layer covering the inner layer and an impermeable membrane interposed between the inner and outer layers. The inner layer is made of a chemically resistant resin not reactive with the medicine, the outer layer is made of an elastic rubber more contractive than the inner layer when the balloon is inflated with the medicine, and the impermeable membrane prevents any additives in the elastic rubber from migrating into the medicine, even if the additives were not previously removed. The balloon can be manufactured in a shorter time than a conventional balloon and will not cause an allergic reaction or anaphylactic shock inherent in untreated elastic rubbers.

Abstract: A prosthetic device to occlude an opening present in a defective atrial septum, the device having at least two clips for firmly gripping peripheral portions around the opening. The material further has a flat occluder to close the opening, and at least two fastening means for securing the clips to the flat occluder. The prosthetic device can be applied to the defective atrial septum permanently and easily in an percutaneous-transvascular manner.

Abstract: An indwelling injector needle assembly having wings includes a cannula or needle body, a hub supporting a proximal end of the needle body, a tube in fluid communication with the needle body, a cylindrical holder having a distal end from which the wings protrude, and a latching mechanism. The hub can slide along an inner periphery of the holder between a first position near the distal end of the holder and a second position near a proximal end of the holder. The latching mechanism is formed in and disposed between the hub and the holder so that the hub is inhibited from moving from the first position toward the second position, and vice versa. The needle edge can be retracted within the holder while its wings remain fixed to a patient's skin.

Abstract: A composite syringe has an injector body and a cylindrical protector which covers a cylinder of the injector body. The protector includes a sleeve separably connected to a base which is secured to an outer periphery of the cylinder's forward end. The sleeve, when separated from the base, is caused to slide towards the cylinder's end and beyond a tip holding a needle, until it engages again with the base at a position where the needle is covered entirely with the sleeve. This prevents any accident of erroneous pricking or puncture of a user of the syringe or other people coming into contact with the syringe.

Abstract: A fluid delivery system including a vial having an opening for containing a dry medicament, a container having an opening for containing a solution, upper and lower, pierceable plugs for hermetically sealing the openings of the vial and the container, respectively, a capsule having upper and lower ends, and a sliding member slidably disposed in the capsule and having a double-pointed cannula providing with upper and lower needles. The container is slidably inserted into the capsule from the upper open end of the capsule and the vial can be detachably and fixedly connected to the lower open end of the capsule. When container is pushed downward, the lower needle of the cannula is firstly pierced and inserted into the plug of the vial so that the cannula is communicated with the medicament vial and then the upper needle of the cannula is pierced and inserted into the plug of the container so that the vial and the container are communicated to each other through the cannula.

Abstract: The antigenicity of a myeloperoxidase is stabilized by applying a solution of cyclodextrin to a myeloperoxidase and incubating the myeloperoxidase with the solution of cyclodextrin. The myeloperoxidase may be immobilized on an insoluble carrier prior to applying the solution of cyclodextrin. The stabilized myeloperoxidase can be stored for a long period of time, even at high temperature, and used as a reagent in an immunoassay.

Abstract: A catheter with an aorta-occluding balloon comprises a tube 1 extending between its L-shaped distal end 8 and its proximal end 9, and having a main lumen 2 formed centrally of the tube, a first and second subordinate lumens 3 and 4, both of them extending longitudinally through the tube's periphery, and a balloon 5 secured to and around the tube's distal end 8. The first lumen 3 has at its end near the proximal end 9 a connector 6 for receiving a balloon-expanding means, and the second lumen 4 also has at its end near the proximal end 9 a further connector 7 for receiving a solution-feeding means. The catheter is thus designed to occlude a calcified blood vessel so that its intima may not be injured, and a fluid such as a protective solution can be supplied to the cardiac muscle through the coronary artery.

Abstract: A drug delivery system including a drug container containing a dose of a dry drug and having a mouth portion sealed by a sealing member including a packing, a spherical closing member and a holding member; a solvent container containing a solvent and having at either ends first and second openings also sealed by a sealing member at least one sealing member for the first opening of the solvent container including a packing, a spherical closing member and a holding member; and a fluid-communication member arranged between the mouth portion of the drug container and the first opening of the solvent container.

Abstract: An emergency resuscitation endoesophageal airway comprises an arch-shaped respiration tube closed at a distal end but opened at a proximal end; a first inflatable balloon of a rubber-like elastic material attached to the respiration tube at a position close to the distal end thereof for closing an esophagus of a patient; a second inflatable balloon of a flexible synthetic resin attached to the respiration tube at a position spaced from the proximal end thereof for closing a pharynx of the patient; and first and second inflating tubes for inflating the first and second inflatable balloons. The respiration tube is provided with air holes between the first and second inflatable balloons but rather near the second inflatable balloon, and the second inflatable balloon is so designed as to expand in both longitudinal and radial directions to an extent much greater than the first inflatable balloon.

Abstract: A medical solution delivery system comprises a cylindrical container having an opening at one end and a port for a medical solution at the opposite end; a plunger slidably arranged in the container; a plunger-driving device for forcing the plunger to move towards the port of the container to deliver a medical solution therethrough; a capsule for holding the container, the plunger and the plunger-driving device; and a flow control device connected to the port of the container to control a flow rate of the solution delivered therefrom. The solution in the container is delivered through a flow control device connected to the port of the container.

Abstract: A blood clarification device wherein a means for measuring blood pressure comprises (a) a needle-detector which is much thinner than the puncture needle and capable of being smoothly inserted into a blood vessel from outside through an inner aperture of the puncture needle, (b) an insertion aperture, for allowing fluid-tight insertion of the needle-detector, positioned on a wall of the blood supply passage in the vicinity of the puncture needle, and (c) a pressure transducer for detecting the blood pressure inside the blood vessel transmitted thereto via the needle-detector. In a blood clarification apparatus of the present invention, blood pressure inside a blood vessel is transmitted to a pressure transducer via a needle-detector during dialysis/filtration operation and blood pressure of a patient is detected continuously and automatically by the pressure transducer.

Abstract: A blood sampler of the suction-type is provided with a gasket, a lancet unit and a plunger slidable in a housing having an open front and an open rear end. A rod is connected at its front end to the lancet unit. The rod extends rearwardly over a detent integral with the inner periphery of the housing, through a central opening of the gasket and into an axial bore of the plunger. A flange, secured to the rear end of the rod is slidable within the axial bore, the gasket is slidable within the housing and behind the detent, and a protrusion formed integral with an intermediate portion of the rod is engageable with the detent. The blood sampler further has a first spring intervening between the detent and the lancet unit, and a second spring accommodated in the bore and intervening between the flange and the front end of the plunger.

Abstract: An adapter 4 fitted in a tube holder 1 is composed of four flexible extensions 23 integral with the forward end of the adapter, and each extension includes a slanted portion 27 and a gripping portion 28 which may have a stopping lug 30 formed on the latter portion. An evacuated tube 3 is closed with a plug 15, which compresses an elastic sheath 12 covering the needle and is pierced by it together with the sheath, when inserted into the adapter 4 for taking a blood sample. The slanted portions 27 are elastically swingable outwardly to render the plug 15 coaxial with the holder 1. The gripping portions 28 are also capable of flexing following the swung slanted portions so that their forward ends are transitionally displaced centrifugally and then restored to their straight position to hold the plug 15 such that even if its outer diameter is considerably smaller than the inner diameter of the holder 1, the sampling needle 2 can penetrate the plug through its central zone and the plug is not "kicked back".

Abstract: A blood separation composition for use in blood collection tubes. The composition comprises, as a gel-like material that is the main ingredient or the composition, a copolymer of sebacic acid with 2,2-dimethyl-1,3-propanediol and 1,2-propanediol. The separation composition may further comprise a thixotropic agent blended with the copolymer. The copolymer renders the blood separation composition stable and less flowable during storage, allowing it to form a stable partition barrier in each collection tube when centrifuged. The blood cells above the barrier are prevented from remaining within the serum, without any amount of harmful oily substances being released from the separation composition.

Abstract: A solvent container to be used in combination with a drug container or vial, which comprises a flexible container body containing a solvent therein and having a mouth covered with a self-sealing member, a guide capsule having an open end sealed by a sealing member and being removably mounted on the mouth of the container body; and a double-pointed hollow needle having a sharp piercing edge at each end and being slidably arranged in the guide capsule to constitute a means for communicating the container body with the drug vial in cooperation with the guide capsule.