Patents Assigned to Novozymes A/S
  • Detergent compositions and uses thereof
    Patent number: 11326130
    Abstract: The present invention relates to polypeptides having hexosaminidase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: January 20, 2021
    Date of Patent: May 10, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Christian B. Oehlenschlaeger, Dorotea R. Segura, Rebecca M. Vejborg, Henrik M. Geertz-Hansen, Lilian E. T. Baltsen, Jesper Salomon
  • Lipase variants, polynucleotides encoding same and the use thereof
    Patent number: 11326152
    Abstract: The present invention relates to lipase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: May 10, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Miguel Duarte Guilherme Toscano, Allan Svendsen, Jesper Vind, Alexander David Fulton, Lone Baunsgaard
  • Use of Polypeptides
    Publication number: 20220135906
    Abstract: The present invention relates to the use of a polypeptide having DNase activity for preventing biofilm on a textile, wherein said textile is unused or unworn. In another aspect, the present invention relates to a composition for preventing, reducing or removing biofilm and/or malodour, comprising a polypeptide having DNase activity and a malodour control component. In another aspect, the present invention relates to a method for preventing biofilm and/or the malodour formation on a textile.
    Type: Application
    Filed: January 13, 2022
    Publication date: May 5, 2022
    Applicant: Novozymes A/S
    Inventor: Isabel Ovejero Lopez
  • Alpha-amylase variants and polynucleotides encoding same
    Patent number: 11319509
    Abstract: The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: May 3, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Carsten Andersen, Chakshusmathi Ghadiyaram, Rajendra Kulothungan Sainathan, Padmavathi Balumuri, Padma Venkatachalam Iyer, Iben Damager, Astrid Munch, Sohel Dalal
  • POLYPEPTIDE, USE AND METHOD FOR HYDROLYSING PROTEIN
    Publication number: 20220127592
    Abstract: The present invention relates to a method for producing a protein hydrolysate using a polypeptide having endopeptidase activity and a polypeptide having carboxypeptidase activity and the use of these enzymes for hydrolysing a protein substrate. In addition, the present invention relates to polypeptides having carboxypeptidase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 28, 2022
    Applicant: Novozymes A/S
    Inventors: Hanne Vang Hendriksen, Gitte Budolfsen Lynglev, Henrik Frisner, Ciu Liu, Ye Liu, Eduardo Antonio Della Pia, Hans Peter Heldt-Hansen, Kenneth Jensen, Wei Peng, Ming Li
  • METHODS AND COMPOSITIONS FOR PREPARING BREAD
    Publication number: 20220125060
    Abstract: The present invention provides a method of producing a baked product having reduced crumb elasticity, said method comprising adding a raw starch degrading alpha-amylase, a lipase and a phospholipase to dough ingredients comprising flour, water, and yeast and mixing to prepare a dough; leavening the dough; and baking the dough to obtain the baked product.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 28, 2022
    Applicant: Novozymes A/S
    Inventors: Guillermo Bellido, Gianluca Gazzola, Irina Matveeva
  • Detergent compositions
    Patent number: 11312946
    Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning. The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: April 26, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Marco Malten, Kim Borch, Lise Munch Mikkelsen, Thomas Agersten Poulsen, Luise Erlandsen, Hanne Philbert Nielsen, Carsten Horslev Hansen, Allan Svendsen, Christian Lundager Gylstorff, Jesper Vind, Christian Jackel
  • Use of Muramic Acid as a Biomarker for Gastrointestinal Peptidoglycan Hydrolysis
    Publication number: 20220119857
    Abstract: Muramic acid measurements in acid hydrolysed digesta samples are used to measure the activity of peptidoglycan hydrolyzing enzyme, as illustrated by the use of a muramidase, as determined by the degree of peptidoglycan hydrolysis, in the gastrointestinal tract of animals fed supplements with the muramidase.
    Type: Application
    Filed: March 20, 2020
    Publication date: April 21, 2022
    Applicant: Novozymes A/S
    Inventors: Mikkel Klausen, Carsten Oestergaard Frederiksen
  • Microbial Lysozyme for use in the Treatment of Irritable Bowel Syndrome or Inflammatory Bowel Disease
    Publication number: 20220118061
    Abstract: The present invention relates to microbial lysozyme, compositions comprising such and uses thereof.
    Type: Application
    Filed: November 2, 2021
    Publication date: April 21, 2022
    Applicant: Novozymes A/S
    Inventors: Soeren Kjaerulff, Marianne Thorup Cohn, Nanna Ny Kristensen
  • Glycosylated beta-galactosidase compositions having improved transgalactosylating activity
    Patent number: 11304425
    Abstract: The present invention relates to compositions, particularly liquid compositions, comprising polypeptides having beta-galactosidase activity, methods of making said compositions, and uses of the compositions for making e.g. dairy products. The polypeptides having beta-galactosidase activity are modified by glycation of lysine and/or arginine residues by incubating the enzyme in the presence of reducing sugars, optionally combined with a heat treatment. Thereby, transgalactosylating activity is increased.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: April 19, 2022
    Assignee: Novozymes A/S
    Inventor: Jeppe Wegener Tams
  • SUBTILASE VARIANTS AND COMPOSITIONS COMPRISING SAME
    Publication number: 20220112476
    Abstract: Provided are subtilase variants having improved stability, detergent compositions comprising the variants, use of the variants and detergent compositions in a cleaning process such as laundry or hard surface cleaning such as dishwashing, and methods of producing the variants.
    Type: Application
    Filed: January 22, 2020
    Publication date: April 14, 2022
    Applicant: Novozymes A/S
    Inventors: Nan Gao, Carl Mikael Bauer, Esben Peter Friis, Rolf Thomas Lenhard
  • ENZYME GRANULES FOR ANIMAL FEED
    Publication number: 20220110343
    Abstract: The present invention is related to feed granules comprising a feed enzyme and a zinc salt of an organic acid.
    Type: Application
    Filed: December 20, 2021
    Publication date: April 14, 2022
    Applicant: Novozymes A/S
    Inventors: Erik Marcussen, Poul Erik Jensen
  • Cognate Foldase Co-Expression
    Publication number: 20220112478
    Abstract: The present invention relates to means and methods for optimizing expression of a heterologous polypeptide of interest in Gram-positive host cells by co-expression with a foldase that is cognate to the heterologous polypeptide of interest.
    Type: Application
    Filed: January 22, 2020
    Publication date: April 14, 2022
    Applicant: Novozymes A/S
    Inventors: Ane Quesada Ganuza, Michael Dolberg Rasmussen, Allan Kent Nielsen
  • CORN FIBER PROCESSING SYSTEM AND WET MILLED CORN STARCH PROCESSING SYSTEM USING SAME
    Publication number: 20220106413
    Abstract: The embodiments of the present application provide a maize fiber processing system and a maize wet-milled starch processing system using same. The maize fiber processing system comprises a pressure curved screen group, a fiber washing sink group, an enzyme preparation adding device and an external enzyme reaction tank, wherein the external enzyme reaction tank is used for receiving screen overflow from a middle stage of pressure curved screen or fiber slurry in a middle stage of fiber washing sink and providing a place for enzyme reaction, thereby extending reaction time of enzyme participation. In addition, the reaction efficiency of the enzyme preparation can be further improved by means of controlling the fiber dry substance concentration in the external enzyme reaction tank.
    Type: Application
    Filed: November 4, 2019
    Publication date: April 7, 2022
    Applicant: NOVOZYMES A/S
    Inventors: Yi Cao, Yongzhong Liang, Jianming Hao, Jieren Luo, Wei Li, Hua Ye
  • SERINE PROTEASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20220090041
    Abstract: The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: December 9, 2021
    Publication date: March 24, 2022
    Applicant: Novozymes A/S
    Inventors: Keiichi Ayabe, Tomoko Matsui, Aki Tomiki-Hashizume, Yuma Kurakata, Esben Peter Friis, Jens Erik Nielsen, Roland Alexander Pache
  • GH9 ENDOGLUCANASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20220089979
    Abstract: The present invention relates to endoglucanase variants and methods for obtaining endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: June 9, 2021
    Publication date: March 24, 2022
    Applicant: Novozymes A/S
    Inventors: Jens Erik Nielsen, Lars Anderson, Allan Svendsen, Rune Nygaard Monrad, Lars Giger, Vasudeva Prahlada Rao, Sohel Dalal, Santhosh Vasu Mepadam, Marie Thrysoe Kruse, Kasper D. Rand, Pernille F. Jensen
  • Detergent Composition
    Publication number: 20220089978
    Abstract: The present invention concerns a detergent and a pharmaceutical composition comprising a deoxyribonuclease (DNase), wherein the DNase is obtained from a fungal source. It further concerns a laundering method and the use of DNase. The present invention further relates to polypeptides having DNase activity, nucleotides encoding the polypeptide, as well as methods of producing the polypeptides.
    Type: Application
    Filed: December 7, 2021
    Publication date: March 24, 2022
    Applicant: Novozymes A/S
    Inventors: Klaus GORI, Marie ALLESEN-HOLM, Lilian Eva Tang BALTSEN, Allan NOERGAARD, Jan LEHMBECK
  • Polypeptides Having Alpha-Mannan Degrading Activity And Polynucleotides Encoding Same
    Publication number: 20220089977
    Abstract: The invention relates to compositions comprising and uses of polypeptides having alpha-mannan degrading activity. The present invention relates to polypeptides having alpha-mannan degrading activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: October 2, 2019
    Publication date: March 24, 2022
    Applicant: Novozymes A/S
    Inventors: Jesper Salomon, Klaus Gori, Lorena González Palmén, Kenneth Jensen, Nikolaj Spodsberg, Mary Ann Stringer, Kristian Bertel Roemer M. Krogh, Morten Gjermansen
  • Glucoamylase variants and polynucleotides encoding same
    Patent number: 11279921
    Abstract: The present invention relates to glucoamylase variants having an increase in raw starch activity compared to the guy-coamylase disclosed as SEQ ID NO: 2, comprising one or more modifications in the catalytic domain and/or one or more modifications in the starch binding domain selected from: a) at least one, preferably at least two, preferably at least three, preferably at least four of: V18M, T43K, N112L, T116R, A117Q, G120S, A271F, Y295W, Q318Y; and/or b) Introducing at least three, preferably at least four substitutions selected from the group: S458C, S458SCGG, S458SGGC, A493V, A518K, E520Q, N527M, S540K, R, S(G)546P, T(V)549W, N503R, N539R+I541Y+T543V+A545S+S546GCGV+G547S+S548T+T549A. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: March 22, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Tomoko Namoto, Noriko Tsutsumi, Keiichi Ayabe, Zhengfang Kang
  • Polypeptides having glucoamylase activity and polynucleotides encoding same
    Patent number: 11279920
    Abstract: The present invention relates to isolated polypeptides having glucoamylase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: March 22, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Ming Li, Junxin Duan, Zheng Liu, Shiro Fukuyama, Keiichi Ayabe, Guillermo Coward-Kelly, Randall Deinhammer