Abstract: An OCT apparatus for acquiring optoretinography data, comprising: an optical system which applies an optical stimulus confined to a portion of a retina of the eye whose location is controllable; an OCT imaging system which acquires OCT data from the retina; and a controller which: acquires a duration of a physiological response of the retina in the optoretinography data to be acquired; acquires target locations on the retina and uses these to control the optical system to apply the optical stimulus to respective first portions of the retina at the respective target locations; controls the OCT imaging system to acquire, for each first portion, respective OCT data of the respective second portion of the retina over the duration indicated by the first indicator, which second portion is stimulated by the optical stimulus applied to the first portion; and generates the ORG data based on the acquired OCT data.

Abstract: An ophthalmic imaging instrument comprising a light source which emits a beam of light, a polygon scanning mirror comprising a plurality of reflecting facets each extending in a respective first direction in a plane of rotation of said mirror and in a common orthogonal second direction, a driver arranged to rotate said mirror such that each facet reflects the beam, an optical element which guides the reflected beam towards an eye and guides light returning from the eye towards the mirror, a detector which detects the returning light reflected from the mirror, and an aperture which constrains the returning light reaching the detector to be that reflected from a region of each facet which extends at least one of a same first distance on each facet in its respective first direction and a same second distance on each facet in the common second direction.

Abstract: A movement mechanism (110) for an ophthalmic imaging apparatus (100) for imaging an eye (120) using light propagating along a first optical path and a second optical path, the movement mechanism arranged to move a first optical element into and out of the first optical path, and concurrently move a second optical element into and out of the second optical path, the movement mechanism arranged to rotate the optical elements between a first rotational position and a second rotational position such that the first and second optical element are: in the first and second optical path, respectively, when the optical elements are at the first rotational position and the imaging apparatus is operating in a first imaging mode; and out of the first and second optical path, respectively, when the optical elements are at the second rotational position and the imaging apparatus is operating in a second imaging mode.

Abstract: A method of processing C-scan data, which comprises a sequence of B-scans of an imaging target acquired by an OCT imaging system, to generate correction data for compensating for axial displacements between B-scans in the sequence caused by a relative motion of the OCT imaging system and the imaging target that varies a distance therebetween during acquisition of the B-scans, the correction data being generated by determining, for each pair of adjacent B-scans of a plurality of pairs of adjacent B-scans in the sequence, a respective indicator of an axial shift between respective representations of a common ocular feature in the adjacent B-scans; and determining, from a variation of the determined indicators with locations of the corresponding pairs of adjacent B-scans in the sequence, a first frequency component of the variation which is indicative of the relative motion during acquisition of the B-scans.

Abstract: An ophthalmic imaging instrument for imaging an eye of a subject, comprising: a light source arranged to emit a beam of light for imaging the eye; an optical system comprising a rotatable mirror and a drive mechanism arranged to drive the rotatable mirror to undergo a predetermined rotational motion to scan the beam of light across the eye; a rotary encoder coupled to the rotatable mirror so as to generate a signal indicative of a rotational motion of the rotatable mirror; and a processor arranged to detect when the rotational motion of the rotatable mirror indicated by the signal has deviated from the predetermined rotational motion and, in response to detecting that the rotational motion of the rotatable mirror has deviated from the predetermined rotational motion, generate a control signal to reduce an illumination of the eye by the beam of light.

Abstract: An information processing apparatus that is communicably connected with another information processing apparatus, the information processing apparatus comprises: a processor configured to execute a program; and a storage device configured to store the program, the processor being configured to execute: acquisition processing of acquiring agreement information relating to the usage of subject eye image data of a patient by the other information processing apparatus; and transmission processing of transmitting the subject eye image data to the other information processing apparatus on the basis of the agreement information acquired by the acquisition processing.

Abstract: A swept-source OCT imaging system for imaging a region of an object, comprising: a swept light source which generates a beam of varying wavelength; a scanning element which scans the beam across the object; an interferometer which generates interference light by combining light scattered by the object (owing to the scan) with reference light; a photodetector which generates an electrical signal (S) having frequency components spanning a frequency band and caused by interference of the scattered light with the reference light; a band-pass filter module which band-pass filters the electrical signal; and a sample acquisition module which samples the filtered electrical signal. The band-pass filter module extracts at least some of the frequency components spanning the frequency band from the electrical signal. The sample acquisition module band-pass samples the filtered electrical signal.

Abstract: An ophthalmic device includes a scanning member, an objective lens, and an optical element. The objective lens includes a first lens group and a second lens group in order from the scanning member side. The optical element is capable of being inserted into and removed from an optical path between the second lens group of the objective lens and the scanning member. In a case in which the optical element is not inserted into the optical path, the objective lens configures a first observation optical system. In a case in which the optical element has been inserted into the optical path, the objective lens and the optical element configure a second observation optical system.

Abstract: A method of processing optical coherence tomography angiography, OCTA, data comprising an array of columns of data elements to generate corrected OCTA data showing reduced projection artefacts in enface projection, the OCTA data having been generated from repeat B-scans, the method comprising: (i) calculating a correlation value indicative of a correlation between a first sequence of the data elements, whose respective locations within respective B-scans correspond to a location of a first data element within the array, and a second sequence of the data elements, whose respective locations within respective B-scans correspond to a location of a second data element within the array; (ii) calculating a correction for the second data element based on the first data element and the calculated correlation value; and (iii) applying the calculated correction to the second data element, wherein processes (i) to (iii) are performed multiple times to generate the corrected OCTA data.

Abstract: An ophthalmic apparatus arranged to determine a distance between the ophthalmic apparatus and an eye, the ophthalmic apparatus comprising: an illumination device which illuminates the eye; an imaging device which acquires an image of the eye, wherein the illumination device and the imaging device are arranged such that the image of the eye comprises a specular highlight from the illumination device having a spatial distribution in the image which varies with the distance between the ophthalmic apparatus and the eye; and a processor arranged to: process the image to determine a value of an indicator which is indicative of a property of the spatial distribution; and use the determined value of the indicator and a mapping which maps values of the indicator to corresponding values of the distance between the ophthalmic apparatus and the eye to determine the distance between the ophthalmic apparatus and the eye.

Abstract: An information processing system comprises: an image acquisition device acquiring subject eye image data of a patient; and a first information processing device communicating with the image acquisition device and storing the image data, the image acquisition device transmits, to the first information processing device, the image data and first transmission data including additional information used to identify an image diagnosis device performing image diagnosis on the image data, the first information processing device: stores the image data when receiving the first transmission data from the image acquisition device; identifies, based on the additional information, a first image diagnosis device performing a first image diagnosis on the image data and/or a second image diagnosis device performing a second image diagnosis differing from the first image diagnosis on the image data; and transmits second transmission data including the image data to the identified image diagnosis device.

Abstract: A control system comprising at least one camera arranged to acquire one or more images of at least a portion of a head of a subject and a processor arranged to process the one or more images to generate a value of a first indicator which is indicative of a height at which the at least a portion of the head, to use at least one mapping to map the value of the first indicator to a value of a second indicator which is indicative of a target height and to generate a control signal for adjusting a height at which a height-adjustable contact surface of the ophthalmic imaging device is disposed to the target height at which the contact surface is to contact the head of the subject during imaging of the eye of the subject by the ophthalmic imaging device.

Abstract: A computer-implemented method of processing respective phase components of a first OCT image and a second OCT image of a sequence of OCT images of a common portion of a retina acquired by a Fourier-domain OCT imaging system after stimulation of the common portion by an optical stimulus, the common portion comprising a layer of the retina whose thickness changed during acquisition of the sequence of OCT images, to determine an indication of a position along an axial direction in the OCT images of a boundary of the layer, the method comprising: processing the phase component of the first OCT image and the phase component of the second OCT image to calculate a velocity profile indicative of a distribution, along the axial direction, of velocity within the common portion of the retina; and determining the indication based on the calculated velocity profile.

Abstract: A computer-implemented method of processing each of a plurality of sets of OCT images in a sequence of OCT images of a portion of a retina to generate a respective indication of a tissue velocity at a position along an axial direction in the OCT images, by performing, for each set: calculating a respective comparison value based on an image quality or similarity of a first OCT image and a second OCT image in the set; using phase information in the first OCT and second OCT image in a calculation of the respective indication of tissue velocity at the position if the comparison value is equal to or greater than a threshold; and omitting the phase information from the calculation if the comparison value is smaller than the threshold.

Abstract: An OCT instrument comprising: an optical coupler which generates signal light and reference light from a swept narrowband light source; a detector which samples a time-varying interference signal based on the reference light and signal light returned from a sample; an adjustable optical frequency shifter which: generates a first sideband light by adjusting an optical frequency of the reference light, such that the detector unit samples a first time-varying interference signal resulting from an interference between the sideband light and the returned signal light; and maintains the optical frequency of the reference light such that the detector unit samples a second time-varying interference signal resulting from an interference between the reference light and the returned signal light. The OCT instrument generates a respective axial depth profile of the sample based on each of the sampled first time-varying interference signal and the sampled second time-varying interference signal.

Abstract: An OCT instrument operable to acquire a B-scan representing a section of a sample, the sample being inclined relative to a plane normal to an axial direction along which depth information of the B-scan is acquired, the OCT instrument being configured to: split light from a swept light source into signal light and reference light; receive signal light reflected from scan locations on the sample; generate sideband light by adjusting an optical frequency of the reference light; sample, for each scan location, a respective time-varying interference signal resulting from interference between the sideband light and the received signal light; generate the B-scan from the sampled signals; and control the optical frequency during the scan such that an image of the sample in the B-scan is less inclined to a lateral direction in the B-scan than in a B-scan of the section acquired by the OCT instrument without the control.

Abstract: An information processing system comprises: an image acquisition device acquiring subject eye image data of a patient; and a first information processing device communicating with the image acquisition device and storing the image data, the image acquisition device transmits, to the first information processing device, the image data and first transmission data including additional information used to identify an image diagnosis device performing image diagnosis on the image data, the first information processing device: stores the image data when receiving the first transmission data from the image acquisition device; identifies, based on the additional information, a first image diagnosis device performing a first image diagnosis on the image data and/or a second image diagnosis device performing a second image diagnosis differing from the first image diagnosis on the image data; and transmits second transmission data including the image data to the identified image diagnosis device.

Abstract: Aspects of the present invention relate to a method of detecting clipping of retinal image content in an optical coherence tomography, OCT, image of a patient's retina. The method comprises detecting a boundary of the retinal image content in the OCT image and calculating a distance between the boundary and an edge of the OCT image. The method further comprises determining if clipping of the retinal image content in the OCT image has occurred by comparing the calculated distance between the boundary and the edge of the OCT image with a clipping threshold distance. Clipping of the retinal image content is determined to have occurred when the calculated distance between the boundary and the edge of the OCT image is equal to, or less than, the clipping threshold distance.

Abstract: An ophthalmic device includes a scanning member, an objective lens, and an optical element. The objective lens includes a first lens group and a second lens group in order from the scanning member side. The optical element is capable of being inserted into and removed from an optical path between the second lens group of the objective lens and the scanning member. In a case in which the optical element is not inserted into the optical path, the objective lens configures a first observation optical system. In a case in which the optical element has been inserted into the optical path, the objective lens and the optical element configure a second observation optical system.

Abstract: Methods and systems for facilitating or improving line scan alignment in a scanning laser ophthalmoscope (SLO) use one or more optical markers located or positioned on a region of an optical element implemented in the SLO device. The optical marker has a predetermined shape and size that assists in detecting any misalignment and/or realigning of the scanned data (such as the line scan) so as to improve the accuracy or integrity of a final scan of a patient's eye.