Abstract: An ophthalmic device comprising a light source to emit fixation target light, and a reflecting face to reflect scanning light emitted by an emission section and scan the scanning light in a specific direction by changing orientation, the emission section being a scanning light source different to the light source. A concave mirror face is disposed so scanning light reflected by the reflecting face is incident on a subject's eye ocular fundus when the eye is at the concave mirror's focal point, and is arranged such that, when the eye is at the concave mirror's focal point, and when the light source emits fixation target light, that light and scanning light are simultaneously incident on the ocular fundus via different optical paths propagating via the concave mirror face and focal point, the target fixation light following a predetermined optical path for fixing the subject's eye gaze.

Abstract: A binocular OCT imaging system for simultaneously imaging regions of a first eye and second eye using an interferometer having a reference arm first sample arm and second sample arm, by: obtaining an electrical signal (S) having first frequency components spanning a first band and caused by interference between reference light in the reference arm with light reflected from the first eye in the first sample arm, and second frequency components spanning a second band and caused by interference between the reference light and light reflected from the second eye in the second sample arm; and generating OCT images of: the region of the first eye using first frequency components in a portion of the first band not overlapping the second band; and the region of the second eye using second frequency components in a portion of the second band not overlapping the first band.

Abstract: A swept-source OCT imaging system for imaging a region of an object, comprising: a swept light source which generates a beam of varying wavelength; a scanning element which scans the beam across the object; an interferometer which generates interference light by combining light scattered by the object (owing to the scan) with reference light; a photodetector which generates an electrical signal (S) having frequency components spanning a frequency band and caused by interference of the scattered light with the reference light; a band-pass filter module which band-pass filters the electrical signal; and a sample acquisition module which samples the filtered electrical signal. The band-pass filter module extracts at least some of the frequency components spanning the frequency band from the electrical signal. The sample acquisition module band-pass samples the filtered electrical signal.

Abstract: There is provided an ocular image capturing device comprising an ocular image generating module operable to generate an image of a subject's eye based on light reflected from the eye, and a determination module arranged to determine whether or not at least a portion of a pupil region of the generated image is within a predetermined permissible region within the generated image, and to generate a signal that is indicative of the determination, the pupil region being an image of at least a portion of the pupil of the eye.

Abstract: A technique for generating a mapping relating values of a scan parameter of an ocular imaging apparatus that are indicative of scan locations in an eye at which the apparatus acquires digital images of imaged regions of the eye, to respective values of a conversion factor for calculating a distance between designated ocular features in the imaged regions, by: simulating light ray propagation to relate each value of the scan parameter in a sequence of scan parameter values to a corresponding location in a model eye; calculating, for each scan parameter value, a distance between the corresponding location in the model eye and a location in the model eye corresponding to an adjacent value in the sequence; and using the calculated distances to generate a respective value of the conversion factor for each scan parameter value.

Abstract: An apparatus for providing temperature-dependent movement of an optical element, the apparatus comprising: a moveable mount for the optical element; a mount moving component attached to the moveable mount; and a guide attached to the mount moving component and configured to guide a movement of the moveable mount. The apparatus is configured such that a difference in thermal contraction or thermal expansion between the mount moving component and the guide in response to a change in temperature of the apparatus causes the mount moving component to move the moveable mount relative to the guide.

Abstract: An ocular imaging system comprising: an image acquisition module which acquires a retinal image; a landmark location prediction module which predicts locations of at least two landmarks in the retinal image; and an apparatus for alerting a user to an unreliability in at least one of the predicted locations. The apparatus receives the predicted first locations; uses the predicted locations to evaluate a distance metric indicative of a distance between the landmark features; use data indicative of a probability distribution of a distance between the landmark features obtained from measurements of the distance in retinal images different from the retinal image to determine an indication of whether the evaluated distance metric lies outside a predetermined interval about a peak the probability distribution; and generates an alert indicating the unreliability when the determined indication indicates that the evaluated distance metric lies outside the predetermined interval.

Abstract: A method, apparatus, and computer-readable medium, for assessing image quality of an image produced by a scanning imaging system. The method comprises acquiring (S10) image data of an image produced by the scanning imaging system and calculating (S20 to S40), for each section of the image: a respective first value measuring at least one of sharpness or contrast of at least a part of the section, the measuring depending on noise, a respective second value measuring noise in at least a part of the section, and a respective third value indicating image quality, by combining the first and second values. The combining is such that calculated third values have a weaker dependency on the noise than the first values. The method further comprises determining (S50) a quality score that is indicative of image quality of the image based on a variation of the calculated third values among the sections.

Abstract: A method of method of processing optical coherence tomography, OCT, image data representing an OCT image of a retina of an eye, to generate mapping data which maps out a predetermined band of a plurality of distinct bands which extend across the OCT image and correspond to respective anatomical layers of the retina. The method comprises: receiving the OCT image data; processing A-scan data of the received OCT image data to generate data indicative of sequences of A-scan elements corresponding to the predetermined band of the plurality of distinct bands and having respective A-scan element values that vary in accordance with a predetermined pattern; and generating the mapping data by applying a line-finding algorithm to determine a line passing through the sequences of A-scan elements indicated by the generated data.

Abstract: A method, system, and computer-readable medium, for detecting whether an eye blink or non-blink is captured in the image. The method includes filtering, from the image, one or more objects that are predicted to be unsuitable for determining whether an eye blink or no-blink is captured in the image, to provide a filtered image. The method also includes correlating the filtered image with a reference image, and determining, based on the correlating, whether the eye blink or non-blink is captured in the image. The eye blink is a full eye blink or a partial eye blink, and the images may be sequentially captured IR SLO images, in one example embodiment herein. Images determined to include an eye blink can be omitted from inclusion in a final (e.g., OCT) image.

Abstract: A method of method of processing optical coherence tomography, OCT, image data representing an OCT image of a retina of an eye, to generate mapping data which maps out a predetermined band of a plurality of distinct bands which extend across the OCT image and correspond to respective anatomical layers of the retina. The method comprises: receiving the OCT image data; processing A-scan data of the received OCT image data to generate data indicative of sequences of A-scan elements corresponding to the predetermined band of the plurality of distinct bands and having respective A-scan element values that vary in accordance with a predetermined pattern; and generating the mapping data by applying a line-finding algorithm to determine a line passing through the sequences of A-scan elements indicated by the generated data.

Abstract: The ophthalmic optical system is configured to apply an angular scanning light ray to an eye. M=|?out/?in| is defined, where ?in represents an angle between an incident light ray to the ophthalmic optical system and an optical axis of the ophthalmic optical system, and ?out represents an angle between an exiting light ray exiting from the ophthalmic optical system toward the eye and the optical axis. The ophthalmic optical system satisfies a conditional expression Mpar<Mmax, where Mpar represents M in a case that the incident light ray is a paraxial ray, Mmax represents M in a case that the incident light ray is a ray of a maximum angle of win.

Abstract: An apparatus for rendering optical coherence tomography, OCT, retinal image data, acquired by an OCT scanner scanning a retina of an eye over a range of scan locations, wherein each scan location is associated with a respective coordinate in a first coordinate system, and each pixel of the rendered OCT retinal image data is associated with a respective coordinate in a second coordinate system different from the first coordinate system. The apparatus comprises a communication module arranged to receive the OCT retinal image data, and a coordinate-determining module arranged to determine values of coordinates in the second coordinate system of pixels in the received OCT retinal image using a transformation from coordinates in the first to second coordinate system. The apparatus further comprises an interpolation module arranged to interpolate between values of pixels at the determined values to calculate values of the pixels of the rendered OCT retinal image data.

Abstract: An information processing apparatus comprises: a processor configured to execute a program; and a storage device configured to store the program, the processor being configured to execute: obtaining processing of obtaining a diagnosis result of both eyes; generation processing of generating diagnosis result display information including a scale indicating a plurality of degrees of progresses related to a symptom, a first index indicating a degree of progress of a right eye based on a diagnosis result of the right eye, and a second index indicating a degree of progress of a left eye based on a diagnosis result of the left eye; and output processing of outputting the diagnosis result display information generated by the generation processing.

Abstract: A method of processing functional OCT image data, acquired by an OCT scanner scanning a retina that is being repeatedly stimulated by a light stimulus, to obtain a response of the retina to the light stimulus, comprising: receiving OCT image data generated by the OCT scanner repeatedly scanning the retina over a time period, and a sequence of stimulus indicators each indicative of a stimulation of the retina by the light stimulus in a respective time interval of a sequence of time intervals spanning the time period; calculating, for each stimulus indicator, a product of the stimulus indicator and a respective windowed portion of the sequence of B-scans comprising a B-scan based on a portion of the OCT image data generated while the retina was being stimulated in accordance with the stimulus indicator; and combining the calculated products to generate the indication of the response.

Abstract: A method of determining control parameters of a retinal treatment system comprising acquiring an image of a retina of a subject's eye using an imaging laser and an optical system of the retinal treatment system, presenting an image of the retina to a user of the retinal treatment system, receiving from the user location data of the retinal image that locates at least one treatment site of the retina, receiving from the user a required laser light pattern for use on the treatment site, using the location data to determine a location control parameter which causes the optical system to direct laser light from a treatment laser of the retinal treatment system to the treatment site, and using the required laser light pattern to determine a pattern control parameter which causes the treatment laser to produce a laser light pattern which passes through the optical system and results in the required laser light pattern at the treatment site.

Abstract: A method of generating a look-up table, LUT, for constructing a dewarped B-scan image from A-scans of a cropped part of a sequence of acquired OCT A-scans, the LUT associating each of a plurality of pixel arrays that are to form the dewarped B-scan image with a respective A-scan in the cropped part. The method comprises: using an indication of a spatial distribution of scan locations of A-scans to determine a dewarp function for selecting, from among acquired A-scans, A-scans having uniformly spaced scan locations; using the function and cropping information, in accordance with which the cropped part is cropped from the acquired sequence, to select, for each array, a respective A-scan from the sequence such that A-scans are selected from the cropped part and have uniformly spaced scan locations; and storing, for each array, a respective pixel array identifier in association with a respective identifier of the selected A-scan.

Abstract: A computer-implemented method, system, and computer-readable medium, for determining a pathologic condition from a medical image of a portion of a subject. The method includes acquiring a plurality of lesion locations in the medical image; applying a clustering algorithm to the plurality of lesion locations to identify at least one lesion cluster and corresponding lesion cluster data; categorizing each lesion cluster into one of a set of predetermined categories based on the identified lesion cluster data; applying at least one function to the lesion cluster data with regard to each category of the set of predetermined categories, wherein the at least one function provides a fixed number of data outputs; and determining a pathologic condition by processing the fixed number of data outputs of each category of the set based on a classification algorithm trained on image data defining medical images of the portion of a plurality of subjects.

Abstract: An optical system, capable to admit a light beam, the optical system comprising: a plurality of reflectors configured to reflect the light beam, wherein each of the reflectors is configured to reflect an incident light beam such that the path of the incident light beam and the path of the reflected light beam are parallel to each other. Each of the reflectors has a reflection center axis positioned centrally between the path of the incident light beam and the path of the reflected light beam. At least two of the reflectors are arranged relative to each other such that their respective reflection center axes do not overlap, thereby enabling the path of the light beam to pass at least one of the at least two of the reflectors multiple times.

Abstract: A medical imaging device comprising: an optical imaging module which generates an image of a region of a body part by acquiring image samples at respective sample locations in the region and mapping the samples to corresponding image pixels; a control module which controls the optical imaging module to acquire a first sequence of samples whose corresponding pixel locations follow a path which is spanned by pixels corresponding to the first sequence of samples and extends over a greater portion of the image than an arrangement in an array of a sequence of pixels corresponding to a second sequence of samples that the optical imaging module is operable to acquire, wherein a sum of distances between adjacent pixels in the sequence of pixels is equal to a length of the path; and a registration module which registers the image against a reference image.