Patents Assigned to Optos PLC
  • Patent number: 11669968
    Abstract: A method of controlling an ophthalmic device operable to image an imaging region of a retina and concurrently illuminate an illumination region of the retina, the method including acquiring a reference retinal image by imaging a reference imaging area of the retina; designating a target in the reference retinal image; acquiring a current retinal image of an initial imaging region within the reference imaging area; moving the imaging region from the initial imaging region to a destination imaging region using the target and the reference retinal image, and acquiring a retinal image of the destination imaging region; illuminating the illumination region while the imaging region is the destination imaging region; acquiring one or more retinal images while the illumination module is being illuminated; and comparing a marker retinal image based on the one or more retinal image(s) with a comparison image based on the reference retinal image.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: June 6, 2023
    Assignee: Optos Plc
    Inventors: Praveen Ashok, Alan Anderson, Gonzalo Muyo, Alistair Gorman, Jano Van Hemert
  • Patent number: 11503994
    Abstract: A computer-implemented method of searching for a region indicative of a pathology in an image of a portion of an eye acquired by an ocular imaging system, the method comprising: receiving image data defining the image; searching for the region in the image by processing the received image data using a learning algorithm; and in case a region in the image that is indicative of the pathology is found: determining a location of the region in the image; generating an instruction for an eye measurement apparatus to perform a measurement on the portion of the eye to generate measurement data, using a reference point based on the determined location for setting a location of the measurement on the portion of the eye; and receiving the measurement data from the eye measurement apparatus.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: November 22, 2022
    Assignee: Optos Plc
    Inventors: Jano van Hemert, Derek Swan
  • Publication number: 20220301157
    Abstract: An information processing system comprises: an image acquisition device acquiring subject eye image data of a patient; a first information processing device storing the image data; a second information processing device obtaining the image data as a first diagnosis result using artificial intelligence; and a third information processing device obtaining the image data as a second diagnosis result by a radiologist, the image acquisition device: generates diagnosis method information indicating a diagnosis by artificial intelligence and/ or a radiologist; and transmits first transmission data including the image data and the diagnosis method information to the first information processing device, the first processing device: stores the image data when receiving the first transmission data from the image acquisition device; and transmits, based on the diagnosis method information, second transmission data including the image data to the second and/ or the third information processing.
    Type: Application
    Filed: July 29, 2020
    Publication date: September 22, 2022
    Applicants: NIKON CORPORATION, Optos plc
    Inventors: Devin SOARES, Branden COLEMAN, Bradley YATES, Koichi ODANI, Zhen LIU
  • Publication number: 20220280034
    Abstract: An information processing apparatus that is communicably connected with another information processing apparatus, the information processing apparatus comprises: a processor configured to execute a program; and a storage device configured to store the program, the processor being configured to execute: acquisition processing of acquiring agreement information relating to the usage of subject eye image data of a patient by the other information processing apparatus; and transmission processing of transmitting the subject eye image data to the other information processing apparatus on the basis of the agreement information acquired by the acquisition processing.
    Type: Application
    Filed: July 29, 2020
    Publication date: September 8, 2022
    Applicants: NIKON CORPORATION, Optos plc
    Inventors: Devin SOARES, Branden COLEMAN, Bradley YATES, Naoyuki KAWACHI
  • Publication number: 20220261989
    Abstract: An information processing system comprises: an image acquisition device acquiring subject eye image data of a patient; and a first information processing device communicating with the image acquisition device and storing the image data, the image acquisition device transmits, to the first information processing device, the image data and first transmission data including additional information used to identify an image diagnosis device performing image diagnosis on the image data, the first information processing device: stores the image data when receiving the first transmission data from the image acquisition device; identifies, based on the additional information, a first image diagnosis device performing a first image diagnosis on the image data and/or a second image diagnosis device performing a second image diagnosis differing from the first image diagnosis on the image data; and transmits second transmission data including the image data to the identified image diagnosis device.
    Type: Application
    Filed: July 29, 2020
    Publication date: August 18, 2022
    Applicants: NIKON CORPORATION, Optos plc
    Inventors: Devin SOARES, Branden COLEMAN, Bradley YATES, Naoyuki KAWACHI
  • Publication number: 20210110537
    Abstract: A method of method of processing optical coherence tomography, OCT, image data representing an OCT image of a retina of an eye, to generate mapping data which maps out a predetermined band of a plurality of distinct bands which extend across the OCT image and correspond to respective anatomical layers of the retina. The method comprises: receiving the OCT image data; processing A-scan data of the received OCT image data to generate data indicative of sequences of A-scan elements corresponding to the predetermined band of the plurality of distinct bands and having respective A-scan element values that vary in accordance with a predetermined pattern; and generating the mapping data by applying a line-finding algorithm to determine a line passing through the sequences of A-scan elements indicated by the generated data.
    Type: Application
    Filed: October 5, 2020
    Publication date: April 15, 2021
    Applicant: Optos Plc
    Inventor: Peter Robert Wakeford
  • Publication number: 20210035301
    Abstract: An information processing apparatus comprises: a processor configured to execute a program; and a storage device configured to store the program, the processor being configured to execute: obtaining processing of obtaining a diagnosis result of both eyes; generation processing of generating diagnosis result display information including a scale indicating a plurality of degrees of progresses related to a symptom, a first index indicating a degree of progress of a right eye based on a diagnosis result of the right eye, and a second index indicating a degree of progress of a left eye based on a diagnosis result of the left eye; and output processing of outputting the diagnosis result display information generated by the generation processing.
    Type: Application
    Filed: July 30, 2020
    Publication date: February 4, 2021
    Applicants: NIKON CORPORATION, Optos plc
    Inventors: Devin SOARES, Branden COLEMAN, Bradley YATES, Naoyuki KAWACHI
  • Publication number: 20210022601
    Abstract: A method of processing functional OCT image data, acquired by an OCT scanner scanning a retina that is being repeatedly stimulated by a light stimulus, to obtain a response of the retina to the light stimulus, comprising: receiving OCT image data generated by the OCT scanner repeatedly scanning the retina over a time period, and a sequence of stimulus indicators each indicative of a stimulation of the retina by the light stimulus in a respective time interval of a sequence of time intervals spanning the time period; calculating, for each stimulus indicator, a product of the stimulus indicator and a respective windowed portion of the sequence of B-scans comprising a B-scan based on a portion of the OCT image data generated while the retina was being stimulated in accordance with the stimulus indicator; and combining the calculated products to generate the indication of the response.
    Type: Application
    Filed: July 16, 2020
    Publication date: January 28, 2021
    Applicant: Optos Plc
    Inventors: Jano van Hemert, Michael Verhoek
  • Publication number: 20200237209
    Abstract: A method of processing a sequence of images of a retina acquired by an ophthalmic device to generate retinal position tracking information indicative of retina movement during acquisition. The method includes (i) receiving one or more images of the retina; (ii) calculating a cross-correlation between a reference image and an image based on the received image(s) to acquire an offset between the image and reference image; and repeating processes (i) and (ii) to acquire, as the tracking information, respective offsets for images that are based on the respective received image(s). Another step includes modifying the reference image during the repeating, by determining a measure of similarity between correspondingly located regions of pixels in two or more received images and accentuating features in the reference image representing structures of the imaged retina in relation to other features in the reference image based on the determined measure of similarity.
    Type: Application
    Filed: August 14, 2017
    Publication date: July 30, 2020
    Applicant: Optos PLC
    Inventor: David Clifton
  • Publication number: 20200242768
    Abstract: A method of controlling an ophthalmic device operable to image an imaging region of a retina and concurrently illuminate an illumination region of the retina, the method including acquiring a reference retinal image by imaging a reference imaging area of the retina; designating a target in the reference retinal image; acquiring a current retinal image of an initial imaging region within the reference imaging area; moving the imaging region from the initial imaging region to a destination imaging region using the target and the reference retinal image, and acquiring a retinal image of the destination imaging region; illuminating the illumination region while the imaging region is the destination imaging region; acquiring one or more retinal images while the illumination module is being illuminated; and comparing a marker retinal image based on the one or more retinal image(s) with a comparison image based on the reference retinal image.
    Type: Application
    Filed: August 14, 2017
    Publication date: July 30, 2020
    Applicant: Optos PLC
    Inventors: Praveen Ashok, Alan Anderson, Gonzalo Muyo, Alistair Gorman, Jano Van Hemert
  • Publication number: 20200237217
    Abstract: An ophthalmic device including an illumination module which scans light across a region of the retina of an a eye when the pupil is disposed at a focal point of the illumination module. The ophthalmic device further comprises components (2, 3-1, 4-1) for: aligning the pupil with the focal point; monitoring a position of the pupil relative to the focal point and maintaining the alignment based on the monitored position; aligning a scan location of the illumination module on the retina to a target scan location while the alignment of the pupil with the focal point is being maintained, wherein the illumination module performs scan at the target scan location The ophthalmic device further maintains the scan location at the target scan location while the alignment of the pupil with the focal point is being maintained, using scan location correction information based on retinal feature information.
    Type: Application
    Filed: August 14, 2017
    Publication date: July 30, 2020
    Applicant: Optos PLC
    Inventors: Alan Anderson, Ian Gourlay, Praveen Ashok
  • Publication number: 20200166676
    Abstract: An optical system comprising: an optical element having an optical property responsive to an applied signal, a variation of the optical property with the signal exhibiting hysteresis in a first range of values and no hysteresis in a second range of values of the signal; a memory storing data representing a hysteresis curve which indicates the variation of the optical property with increasing and decreasing values of the signal; and a controller which continuously controls the optical property by: generating, based on the stored data, a cyclic signal having a discontinuity in each cycle of the cyclic signal, and setting the discontinuity size in each cycle based on the stored data such that a part of the variation of the optical property with the cyclic signal coincides with a part of the variation represented by the stored data; and applying the cyclic signal to the optical element.
    Type: Application
    Filed: August 14, 2017
    Publication date: May 28, 2020
    Applicant: Optos PLC
    Inventors: Alan Anderson, Praveen Ashok, Hiroshi Kasai, Alistair Gorman
  • Patent number: 10398310
    Abstract: An ophthalmoscope (1) and method for scanning a fundus (23) of an eye (9), comprising a light system (3) which produces linear light, a scanner (5) which receives at least some of the linear light and is movable about a scan axis to produce a 1D scan of the at least some linear light, and a scan transfer system (7) which receives the 1D scan from the scanner and transfers the 1D scan to the eye, wherein the scanner is positioned in the ophthalmoscope such that it receives the at least some of the linear light substantially along the scan axis, the scan transfer system positioned in the ophthalmoscope such that a pupil of the eye is provided at a focal point of the system, and the scanner is positioned in the ophthalmoscope and the scan transfer system is configured to transfer the 1D scan from the scanner through the focal point at the eye pupil and onto the eye fundus.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: September 3, 2019
    Assignee: Optos PLC
    Inventors: Derek Swan, Gonzalo Muyo, Alistair Gorman
  • Patent number: 10349825
    Abstract: A method of determining a measurement of at least one cell type in an eye, comprising (i) obtaining a map of the cell type in the eye, (ii) obtaining a representation of the retina of the eye, (iii) matching the eye cell type map to the representation of the retina of the eye, (iv) defining a region of interest on the representation of the retina of the eye, (v) calculating a size of the region of interest on the representation of the retina of the eye, (vi) using the matched eye cell type map and the size of the region of interest to determine a measure of the cell type in the region of interest of the retina of the eye.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: July 16, 2019
    Assignee: Optos PLC
    Inventors: Jano van Hemert, Michael Verhoek, David Brown, Charles Wykoff, Daniel Croft
  • Patent number: 10335028
    Abstract: Apparatus for illuminating the retina of an eye. The apparatus includes an illumination device and a lens system. The illumination device and the lens system combine to provide incident illumination from an apparent point source located within the lens system. The apparatus also includes an illumination transfer device. The illumination transfer device has two foci and the apparent point source of the lens system is provided at a first focus point of the illumination transfer device and an eye is accommodated at a second focus point of the illumination transfer device. The illumination transfer device transfers the incident illumination from the apparent point source into the eye to illuminate the retina.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: July 2, 2019
    Assignee: Optos PLC
    Inventors: Christopher David Creasey, Stuart Brian Milne, Andrew Fogg
  • Patent number: 10292582
    Abstract: An ophthalmoscope (10) comprising a light source (12), a first scanner (14), a first scan transfer element (16), a second scanner (18), and a second scan transfer element (20), which provide a two-dimensional scan of incident light from an apparent point source at a pupillary point of an eye (22) onto the fundus of the eye, and which descan a two-dimensional scan of return light from the fundus of the eye to provide return light from an apparent point source at the first scanner, wherein the first scan transfer element comprises a free-form element which has a shape defined to provide aberration correction of the return light from the fundus of the eye.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: May 21, 2019
    Assignee: Optos PLC
    Inventors: Gonzalo Muyo, Derek Swan
  • Patent number: 9924862
    Abstract: A scanning laser ophthalmoscope (SLO) for imaging the retina of an eye comprises a source (12) of collimated light, a scanning device (14, 16, 1328, 1319), a scan transfer device (20) and a detector (1310). The scan transfer device has a first focus (16) at which an apparent point source is provided and a second focus (24) at which an eye (524, 1324) may be accommodated. The scan transfer device transfers a two-dimensional collimated light scan from the apparent point source into the eye. An optical coherence tomography (OCT) system (900) is combined with the SLO, the OCT system providing OCT reference and sample beams. The OCT sample beam (902) propagates along the same optical path as of the SLO collimated light through the scan transfer device. An aberration compensator (1204, 1316) automatically compensates for systematic aberrations and/or changes in wavefront introduced by scanning elements and the scan transfer device as a function of scan angle.
    Type: Grant
    Filed: October 1, 2013
    Date of Patent: March 27, 2018
    Assignee: Optos PLC
    Inventors: William Brown, Michael E. Sullivan, Anthony Corcoran, Derek Swan
  • Publication number: 20170049315
    Abstract: A method of determining a measurement of at least one cell type in an eye, comprising (i) obtaining a map of the cell type in the eye, (ii) obtaining a representation of the retina of the eye, (iii) matching the eye cell type map to the representation of the retina of the eye, (iv) defining a region of interest on the representation of the retina of the eye, (v) calculating a size of the region of interest on the representation of the retina of the eye, (vi) using the matched eye cell type map and the size of the region of interest to determine a measure of the cell type in the region of interest of the retina of the eye.
    Type: Application
    Filed: May 1, 2015
    Publication date: February 23, 2017
    Applicant: Optos PLC
    Inventors: Jano van Hemert, Michael Ver-Hoek, David Brown, Charles Wykoff, Daniel Croft
  • Patent number: 9390499
    Abstract: A laser scanning ophthalmoscope obtains images of a retina. An image is processed by (i) mapping an image along a one dimensional slice; (ii) computing a wavelet scalogram of the slice; (iii) mapping ridge features from the wavelet scalogram; repeating steps (i), (ii) and (iii) for one or more mapped image slices. The mapped ridge features from the slices are superimposed. Textural information is derived from the superimposed mapped ridge features. The analysis can be tuned to detect various textural features, for example to detect image artifacts, or for retinal pathology classification.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: July 12, 2016
    Assignee: Optos PLC
    Inventor: David Clifton
  • Publication number: 20160157714
    Abstract: A method of reducing jitter error in a laser scanning system adapted to produce a scanned image including a number of lines of an object. The method includes the steps of providing a reference object arranged such that the scanned image produced by the laser scanning system includes a reference image of the reference object, processing the reference image to calculate an error arising from non-repeatable displacement of the lines of the reference image, and adjusting at least one operating parameter of the laser scanning system in response to the calculated error.
    Type: Application
    Filed: February 2, 2016
    Publication date: June 9, 2016
    Applicant: Optos PLC
    Inventor: Hind Azegrouz