Patents Assigned to Orion Genomics LLC
  • Comprehensive DNA methylation profiling in a human cancer genome identifies novel epigenetic targets
    Publication number: 20070224626
    Abstract: The present invention provides DNA marker sequences that are differentially methylated in samples from normal individuals and individuals with brain cancer. The invention further provides methods of identifying differentially methylated DNA marker sequences and their use the detection and diagnosis of gliomas.
    Type: Application
    Filed: March 8, 2007
    Publication date: September 27, 2007
    Applicant: Orion Genomics LLC
    Inventors: Jeffrey Jeddeloh, Jared Ordway
  • Differential enzymatic fragmentation by whole genome amplification
    Publication number: 20050272065
    Abstract: The present invention provides methods for detecting the presence of methylation at a locus within a population of nucleic acids.
    Type: Application
    Filed: March 2, 2005
    Publication date: December 8, 2005
    Applicant: Orion Genomics LLC
    Inventors: Nathan Lakey, Jeffrey Jeddeloh, Yulia Korshunova
  • Methods for quantitative determination of methylation density in a DNA locus
    Publication number: 20050153316
    Abstract: The present invention is a novel method of determining the average DNA methylation density of a locus of interest within a population of DNA fragments.
    Type: Application
    Filed: October 21, 2004
    Publication date: July 14, 2005
    Applicant: Orion Genomics LLC
    Inventors: Jeffrey Jeddeloh, Nathan Lakey