Abstract: The invention relates to a gelatine capsule containing selegiline, its structurally related compounds or their pharmaceutically acceptable salts as the active ingredient and paraffin as a carrier. Preferably, the gelatin capsule is a soft gelatine capsule, and paraffin is substantially in liquid form.

Abstract: The invention relates to a transfer device for generating a regular, linear transfer movement especially for reading an image plate used in X-raying. The transfer device comprises a fixed housing, a rotatable threaded bar (5), a slide (6) moving linearly on the bar, slide guides (9, 10) for controlling the linear movement of the slide, and members for transforming the rotational movement of the bar into the linear movement of the slide. In accordance with the invention, these members consist of two followers (8) elastically articulated in the slide (6) and placed on opposite sides of the threaded bar (5), each of which is provided with a tongue (15) elastically stressed in the threaded groove (7) of the bar, the stressing member consisting of a pull device (19, 21) fitted between the followers and interconnecting the followers elastically in the transverse direction of the threaded bar. The pull device may consist of a magnet (19) and its counterpart (21), or optionally of a draw-spring between the followers.

Abstract: The present invention relates to a specific cuvette, an assay method and a diagnostic test kit where samples of whole blood can be used for quantitative diagnostic testing without need for centrifugation, even though the blood components to be analyzed are in the plasma fraction. Using the method of the present invention the blood sample is converted into a plasma fraction and a cell fraction by shaking in a cuvette in the presence of a special agglutinating reagent A plasma fraction is obtained which is suitable to be used in diagnostic tests using immunometric or colormetric methods or test strips without physically removing the blood cells from the sample.

Abstract: A pharmaceutical composition is provided for use in the prevention or treatment of osteoporosis comprising a therapeutically effective amount of a compound of formula (I) ##STR1## wherein R.sub.1 and R.sub.2 are independently H or OH, for the treatment or prevention of osteoporosis and a pharmaceutically acceptable carrier.

Abstract: The present invention provides a method for the pretreatment of object surfaces prior to taking a sample for microbial analysis. The method uses a blend to remove biofilms without hindering the growth of microorganisms. The method allows for reliable and replicable determination of microorganisms formed on the investigated surfaces.

Abstract: A drive system for a drive wheel of a vehicle having a hub. The drive system includes a frame, a sun gear including toothing on an outer surface, a motor arranged to rotate the sun gear via an output shaft, a revolving circular, a peripheral gear including toothing on an inner surface, and planetary gears interposed between the sun gear and the peripheral gear and engaging with the toothing of the sun gear and the toothing of the peripheral gear. Each planetary gear has a shaft connecting to the hub of the vehicle. A rotatable sleeve shaft surrounds at least a part of the output shaft and has a toothing on an outer surface. The peripheral gear is arranged relative to the sleeve shaft such that the toothing of the peripheral gear engages with the toothing of the sleeve shaft. A clutch/brake element is arranged between the sleeve shaft and the frame for controlling rotation of the sleeve shaft.

Abstract: The present invention relates to a method and a circuit arrangement for controlling a stepper motor, e.g. in a panoramic X-ray apparatus. In the method of the invention, the control data of a processor (5) is first converted into an analog signal with a digital-analog converter (6), and the signal thus obtained is integrated with an integrating circuit (7,10), whereafter the signal is converted into pulses controlling the stepper motor (9) with a voltage-frequency converter (8). The circuit arrangement comprises preferably one or two integrators. In consequence, the changes in the speed of rotation of the stepper motor can be made stepless, whereby the stresses directed at the mobile parts are small, and mechanical oscillation caused by high momentary forces is avoided. In addition, the loading of the processor can be made uniform. Error correction circuits employing feedback are employed to enhance operation of the invention.

Abstract: Aminoterminal propeptide of type I procollagen exists in serum in two forms: classical type I procollagen which is a heterotrimer containing two pro .alpha.1-chains and one pro .alpha.2-chain of type I procollagen, and an .alpha.1-homotrimer type I procollagen containing three identical pro .alpha.1-chains. These intact, trimeric aminoterminal propeptides may be isolated without the use of proteolytic enzymes and the resultant propeptides may be used to prepare antibodies specific for the intact trimeric propeptide, having no affinity for the monomeric form of the propeptide. Such antibodies are useful in methods of assaying intact trimeric aminoterminal propeptide of type I procollagen in serum, without false information resulting from inadvertent assay of the monomeric form of the propeptide.

Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.

Abstract: This device is intended for the dispensing of a powdered medication by inhalation. The device includes a powder container (1), an air channel (2), and a metering strip (4) equipped with a dosing recess (3). The metering strip (4) can be moved along a flat surface (5) from a filling position, in which the dosing recess (3) is filled with powder coming from the container (1), to an inhalation position, in which the dosing recess (3) is in the air channel (2).

Abstract: The invention relates to long-acting pharmaceutical compositions from which the release of the active compound increases exponentially, and to a process for their preparation. The composition, preferably a tablet, comprises a rapid releasing core and a slow-releasing coat surrounding that core.

Abstract: A filter arrangement in a radiography apparatus in order to define the intensity of the radiation beam incident upon the object. To the movable filter part in front of the radiation source (2) there is coupled an electric circuit element, for example a potentiometer, from which the signal is applied further to a row (8) of light-emitting diodes in the vicinity of the object to be radiographed, for example the patient's head (7). When the filter is moved, the electric signal controls the light-emitting diodes so that the light-emitting diodes which become illuminated in the row will indicate the boundary of the filtered radiation beam at a given time.

Abstract: Equipment for automatic adjustment of image receptor exposure during imaging in panoramic or tomographic radiography. The equipment includes: a radiation source (4) and an image receptor (7), the radiation (5) passing through the object (6) to be X-ray examined, placed between these; at least two interspaced detectors (1), placed behind the image receptor and measuring the radiation intensity; memory means for storing exposure reference values; and adjustment means (3), which adjust variables affecting the image receptor exposure during X-raying on the basis of signals from the detectors and reference values. The apparatus also includes an integrator for each separate detector (1a, 1b, 1c, . . .

Abstract: A new stable solid composition suitable for oral administration comprising a pharmaceutically acceptable acid addition salt of selegiline is achieved by reducing the destabilizing effect of the conventional lubricant present in such compositions, magnesium stearate either by replacing all or a substantial part of the magnesium stearate by other lubricants such as fatty acid esters and vegetable oils and/or by adding a pharmaceutically acceptable acid to the selegiline-containing tablets.

Abstract: The invention relates to a method of sensitizing cancer cells for a killer cell mediated lysis which involves administering to a patient an effective amount of antiestrogen and killer cells either jointly or sequentially, wherein the killer cells are selected from the group of NK cells, LAK cells and CTL cells and the antiestrogen is selected from the group of triphenylethylene class antiestrogens, such as tamoxifen or toremifene or their pharmaceutically acceptable salt.

Abstract: A bioceramic system for delivery of a bioactive compound, which comprises a combination of bioactive glass, bioactive glass ceramic or bioactive ceramic, hydroxyapatite, optionally one or more other calcium phosphate compound and optionally a matrix, and which may incorporate into the bioceramic system a bioactive compound. The timing of the release of the bioactive compound can be regulated as desired and depends on the conditions of the surrounding, the composition of the bioceramic system and its method preparation.

Abstract: Compounds having formula (I) wherein R.sub.1 and R.sub.2 are independently H or OH, are useful in the treatment and prevention of osteoporosis. The compounds of formula (I) are devoid of significant antiestrogenic and estrogenic activity.

Abstract: A valve for use in connection with aerosol spacers to be mounted on a metered dose inhaler, characterized in that the valve comprises a frame portion (1) one end of which can be attached to the chamber portion of known aerosol spacers and its other end constitutes a mouthpiece having an air outlet aperture (4) for expiratory air and an air inlet aperture (6) for the air to be inhaled via the inhaler chamber, and a flap (3) which is to be fitted inside the mouthpiece and slides freely in the direction of the longitudinal axis of the mouthpiece so that, upon inhalation, it will open the air inlet aperture (6) and close the air outlet aperture (4) and upon exhalation, it will close the air outlet aperture (4), and upon exhalation, it will open the air outlet aperture (4) and close the air inlet aperture (6).