Abstract: A dosing mechanism (6) for delivering a plurality of single metered doses includes a dose delivery mechanism; and a non-return mechanism (10), arranged to prevent the dose delivery mechanism from returning toward a primed position until a full metered dose has been delivered. The non-return mechanism includes a track defining an actuation path and a return path and an engagement member arranged to be received within the track. The track and engagement member are relatively moveable such that the engagement member is arranged to move along the actuation path during actuation of the dose delivery mechanism and along the return path during priming of the dose delivery mechanism. At least a portion of the actuation path is provided with a toothed profile to prevent reverse movement of the engagement member in the actuation path.

Abstract: A display arrangement for e.g. a medical substance delivery device includes a movable control member, at least one transducer responsive to movement of the control member to convert mechanical energy into electrical energy to output an electrical signal, a drive circuit for receiving the electrical signal and for outputting an output drive signal, and a display device for receiving the output drive signal and displaying a variable image that varies consequent on the relative movement. The display may be a bistable display, so that the display function is self-powered without a requirement for a battery or the like. The parameter displayed for a medical substance delivery device may be a dose volume, a count of doses delivered, progress and/or completion of a dose. The drive circuit is an absolute position encoder and detects the actual position of the control member and does not deduce the position by counting pulses.

Abstract: A substance delivery device (autoinjector) for use with a container (such as a syringe) containing the substance includes: a body arranged to house or hold the container; a plunger which is movable with respect to at least a portion of the body, the plunger being arranged to act upon the container so as to move the container with respect to the portion of the body; wherein the plunger is also arranged to expel at least a portion of the substance from the container; and wherein the device includes elements for adjusting the amount of substance to be expelled from the container. The device can also have elements for priming the container, and can accommodate containers of different size or shape.

Abstract: An autoinjector includes a rear body assembly (10) connected to a front body assembly, wherein the rear body assembly (10) contains a drive mechanism (60 . . . ) and the front body assembly contains a syringe (13) or cartridge with a needle at its forward end, the front body assembly including a viewing window (22) through which at least part of the contents of the syringe (13) or cartridge are visible, a removable cap (14) fitted to the forward end of the front body assembly the rear body assembly and the removable cap having respective aligned cut-away regions together defining a frame for the viewing window. Also disclosed is a modular scheme which uses a common platform for the provision of a range of autoinjectors of different fill volumes, with only the length of the plunger (60), and the axial extent of the cut out varying between different versions.

Abstract: An autoinjector includes a housing for receiving in use in a generally longitudinal loading direction a syringe assembly including a syringe carrier and a syringe, the syringe including a syringe body having a slideable internal piston for expressing a dose contained in the body through a needle at a forward end thereof; a drive mechanism for providing drive for operation of the autoinjector and being disposed generally within the housing and including a mechanical energy source and a winder element for being rotated to charge the energy source, and an input transmission train operational between the syringe assembly and the winder element in use, whereby loading of the syringe assembly into the housing rotates the winder element to charge the energy source.

Abstract: An injection device includes an elongate housing (10), a syringe (12) disposed in the housing, and an internal piston (20) to express a dose from a needle (16) at its front end. The injection device further includes a shroud element (24) movable forwardly relative to the syringe to shroud the needle after use and a latch (74) movable between a latched state in which it restricts rearward movement of the shroud element, and a release state. The latch is moved to its latch state by a magnetic force (56).

Abstract: An autoinjector device includes an elongate housing containing a syringe or cartridge having an internal piston for expressing a dose from the syringe or cartridge. A drive mechanism includes a drive member engaging the piston and a drive spring acting on the drive member. A side-operated trigger arrangement includes a retention element movably mounted in the housing from a retaining position in which the drive member is kept in a cocked condition, and a release position in which the drive member may more forwardly under spring pressure. An outer sleeve is mounted on the housing movable between a position in which the retention element is prevented from moving to release the plunger, and a position in which the retention member moves freely. The outer sleeve includes a trigger wall portion which may be depressed to move the retention element once the retention element is free to move, releasing the plunger.

Abstract: An injection device includes a housing, a plunger, a drive gear and a release trigger. The plunger includes a leadscrew and a cap attached thereto where, in use, the cap engages a bung of a cartridge containing medicament. The drive gear within the housing engages with the leadscrew such that rotation of the drive gear around the leadscrew drives the plunger axially through the housing towards the bung. The trigger includes a locking ring having generally axially extending teeth for engaging with corresponding teeth on the drive gear. The trigger is generally axially movable between an engaged position where the teeth are engaged and prevent rotation of the drive gear, and a disengaged position where the teeth are disengaged and enable rotation of the drive gear. Movement of the trigger between the disengaged and engaged position causes counter-rotation of the drive gear and retracts the plunger away from the bung.

Abstract: A blood sampling device includes a housing and a lancet supporting a lancet needle or tip, the lancet and needle being urged or urgeable in a pricking direction. A trigger mechanism is moveable to a fire position for releasing the lancet to travel in the pricking direction. A removable safety cap initially covers the lancet needle. The lancet has an initial position in which movement of the trigger mechanism to the fire position is blocked and an intermediate position in which the trigger mechanism may be moved to the fire position. The intermediate position is obtainable only on removal of the safety cap.

Abstract: A substance delivery device for delivering a substance from a container includes a body, and a plunger movable with respect to the body so as to expel at least a portion of a substance from the container, a trigger mechanism, a latch member latched in a stationary position at least along the longitudinal axis of the device before use, and a lockout shroud movable along the longitudinal axis relative to the latch mechanism. User manipulation of the trigger mechanism causes the latch mechanism to become unlatched and move along the longitudinal axis and to cause movement of a plunger relative to the body, and in a first position of the lockout shroud along the longitudinal axis relative to the latch member, the lockout shroud prevents the trigger mechanism from unlatching the latch member, whereas in a second position the lockout shroud allows the trigger mechanism to unlatch the latch member.

Abstract: An injection device includes an injection complete indicator which includes its own bias and which is latched into a retracted position as the injection device is cocked. Upon firing the injection device, the injection complete indicator is kept in its retracted position until towards the end of the forward stroke of the drive mechanism, whereupon the injection complete indicator is unlatched and shoots forwardly under the influence of the bias to impact an abutment to generate an audible/tactile indication along with a visual indication.

Abstract: Skin stimulus arrangements are described for creating a stimulus in the skin in the vicinity of a treatment or wound site to alleviate the perception of pain. First and second textured surfaces are provided for making contact with the skin, with the surfaces being moved to create a stimulus which alleviates the perception of pain. The movement may be linear, rotary or a combination of both, and just a single textured surface may be provided.

Abstract: An injection apparatus includes a counter wheel that is incremented by the dose delivery mechanism each time the device is fired. The apparatus includes a final dose disabling mechanism that prevents further usage once the final dose has been delivered. An anti-tamper feature is provided to prevent inadvertent or premature initialisation of the apparatus.

Abstract: An autoinjector includes a body (10, 12), a syringe (13) or cartridge disposed within the body, and a plunger (60) moveable during operation between a first and a second position to effect an injection, the plunger including a transverse passage (66) containing a moveable magnetic element (68) of a magnetic pair, the body including another magnetic element (54) at a position such that, on the plunger reaching and/or nearing its second position, the magnetic attraction therebetween causes a sound-emitting impact, the plunger (60) including a magnetic keeper element (72) mounted adjacent the transverse passage and adapted to hold the movable magnetic element (68) against movement until attraction by the other magnetic pair element (54), wherein the keeper element (72) is disposed on the longitudinal axis.

Abstract: An autoinjector includes a housing (10) to receive a syringe (14), and a drive mechanism including first and second springs (30, 32) operating in tandem via an intermediate member (34), on a plunger (42). The plunger is retained in a locked position by a trigger. Release of the trigger causes the first spring to advance the syringe to an arrest point whereafter the second spring extends within the syringe to expel a dose.

Abstract: An injection device includes a housing for receiving a syringe or cartridge for containing a medicament; a rotary driveshaft mounted for rotation relative to the housing; and an elongate coiled torsion spring having respective formations at opposite ends thereof, with a first formation being anchored in a seat on the rotary drive shaft and a second formation being anchored in a seat on a reaction component. In use relative rotation of the rotary driveshaft and the reaction component in one angular direction strains the torsion drive spring, and release of the strained torsion drive spring causes expression of medicament from the syringe or cartridge. The torsion spring is longitudinally resiliently compressible between its end formations whereby during assembly of the injection device, the torsion spring may be longitudinally compressed and then rotated, thereby urging the end formations of the torsion drive spring into engagement with the respective seats.

Abstract: An autoinjector has a main body (10, 12) containing a syringe (13) or cartridge with a needle at its front end for being moved forwardly in the body to extend the needle from the body for an injection, the body housing in a forward region a shroud (24) having a forward portion of generally tubular form (32), the shroud being moveable longitudinally between a rearward retracted position and a forward extended position, the autoinjector further including a spring arrangement for biasing the shroud forwardly, the spring arrangement (44) including two springs disposed alongside and spaced from the longitudinal axis.

Abstract: A lancing device includes a housing (10, 12) and a lancet holder movably mounted within the housing. The lancet holder has a forward portion defining a socket (30) for partially surrounding and retaining in use the rear portion of a lancet. A lancet release element (40, 42) can be moved forward to cooperate with lugs on the socket to expand it to allow insertion and/or removal of the lancet with minimal insertion or withdrawal force.

Abstract: An autoinjector has a body portion (10, 12) containing a syringe (13) or cartridge with a needle at its forward end, the autoinjector having a drive arrangement (60 . . . ) for effecting operation of the autoinjector and including a drive element that moves from a first position to a second position during the operation, the body including a first (10) and a second body portion (12) connected together by a snap fit arrangement including a resiliently moveable latch finger (138) on one of the body portions that cooperates with a latch surface (142) on the other thereof to hold the two portions connected, wherein the drive element in the second position (60) limits or prevents resilient movement of the moveable latch finger (142), thereby preventing disconnection of the first and second body portions after operation.

Abstract: An injection device operable to deliver a dose of medicament from a syringe or cartridge includes a temperature-sensitive arrangement for inhibiting operation thereof under predetermined temperature conditions. This may include a thermally responsive element that adopts a position in which operation of the device is inhibited when a temperature level is passed.