Patents Assigned to Oxford University
  • Particle characterisation in open optical resonator cavity
    Patent number: 10948397
    Abstract: Characteristics of polarizable particles in a fluid are detected using an optical cavity comprising opposed optical reflectors containing the fluid. A particle is introduced through the fluid into the optical cavity. The particle may be transiently in the cavity or optically trapped. The optical cavity containing the particle is illuminated with light that excites resonance of an optical mode of the optical cavity that is affected by the particle. A measurement of a parameter of the excited resonance is derived, for example while tuning through the resonance. Repeated measurements may be used to derive a measure of a characteristic of the particle that is dependent on the motion of the particle in the optical cavity.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: March 16, 2021
    Assignee: Oxford University Innovation Limited
    Inventors: Aurélien Trichet, Jason Michael Smith, Claire Vallance
  • Droplet assembly method
    Patent number: 10950376
    Abstract: The invention relates to a process for moving a droplet from a first location to a second location, which droplet comprises a magnetic material disposed in an aqueous medium. The invention also relates to a droplet assembly comprising a droplet, which droplet comprises a magnetic material disposed in an aqueous medium. Various uses of the droplet assembly are also described.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: March 16, 2021
    Assignee: Oxford University Innovation Limited
    Inventors: John Hagan Pryce Bayley, Kunwar Tanuj Sapra, Tobias Wauer, Holger Gerlach, Shiksha Mantri, Jamie Hill
  • Method and apparatus for vital signs measurement
    Patent number: 10939852
    Abstract: A method of monitoring changes in oxygen saturation of a subject by analysing a three colour channel video image of the exposed skin of the subject. Within each colour channel a normalised signal obtained by dividing the intensity signal by its mean value, and the normalised signals are averaged across plural regions of interest within the exposed skin area image of the subject. Regions of interest are selected on the basis of the signal-to-noise ratios for the heart rate and breathing rate components. A single representative waveform for each colour channel is obtained by signal averaging and the ratio of the amplitudes of the representative waveforms from two different colour channels, e.g. blue and red, is taken. The changes in the ratio of amplitudes is output as a measure of changes in blood oxygen saturation.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: March 9, 2021
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Alessandro Guazzi, Mauricio Villarroel Montoya, Lionel Tarassenko
  • Method for trapping vacancies in a crystal lattice
    Patent number: 10934635
    Abstract: There is provided a method of fabricating a trapped vacancy in a crystal lattice of a target comprising: positioning the target in a laser system, the target containing vacancy trapping elements within the crystal lattice; modifying the crystal lattice within the target by using a laser to generate a lattice vacancy; and annealing the target to cause the lattice vacancy to migrate and be captured by a vacancy trapping element to form the trapped vacancy in the crystal lattice.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: March 2, 2021
    Assignee: Oxford University Innovation Limited
    Inventors: Martin James Booth, Patrick Salter, Jason Smith, Yu-Chen Chen
  • Method of analysing DNA sequences
    Patent number: 10934578
    Abstract: The present invention relates to a method of identifying nucleic acid regions within a nucleic acid sample which interact with one another. In particular, the method relates to a chromatin conformation capture (3C) method which may be used to analyse the interactions between enhancers, silencers, boundary elements and promoters at individual loci at high resolution.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: March 2, 2021
    Assignee: Oxford University Innovation Limited
    Inventors: James R. Hughes, James Davies
  • Double perovskite
    Patent number: 10927013
    Abstract: The present invention relates to a semiconductor device comprising a semiconducting material, wherein the semiconducting material comprises a compound comprising: (i) one or more first monocations [A]; (ii) one or more second monocations [BI]; (iii) one or more trications [BIII]; and (iv) one or more halide anions [X]. The invention also relates to a process for producing a semiconductor device comprising said semiconducting material. Also described is a compound comprising: (i) one or more first monocations [A]; (ii) one or more second monocations [BI] selected from Cu+, Ag+ and Au+; (iii) one or more trications [BIII]; and (iv) one or more halide anions [X].
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: February 23, 2021
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Henry James Snaith, Amir Abbas Hagighirad, Feliciano Giustino, Marina Filip, George Volonakis
  • Methods for monitoring motion using multi-transmit electrical coupling in imaging of the subject
    Patent number: 10928478
    Abstract: Described herein are methods for monitoring and/or extracting subject motion from multi-channel electrical coupling in imaging of the subject, in particular in magnetic resonance (MR) imaging of the subject.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: February 23, 2021
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Aaron Hess, Matthew Robson, Sven Jaeschke
  • Electrochemical method and apparatus
    Patent number: 10928350
    Abstract: Herein is disclosed a method for detecting a material comprising a thiol group (e.g. homocysteine, cysteine, glutathione) in a sample, the method comprising: •providing an electrode comprising a carbon material; •contacting said electrode with said sample in the presence of catechol or more generally a precursor of ortho-quinone; •performing cyclic or square wave voltammetry to convert catechol to ortho-quinone and wherein said ortho-quinone reacts with the material comprising a thiol group to form an electrochemical reaction product.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: February 23, 2021
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Patricia Tung Lee, Denise Lowinsohn, Richard Guy Compton
  • Magnetoinductive waveguide
    Patent number: 10931252
    Abstract: A re-configurable magnetoinductive waveguide (300), comprising a plurality of resonator cells, wherein each resonator cell comprises a primary resonator (110) that is inductively coupled to a primary resonator (110) of at least one other resonator cell, and wherein at least one of the plurality of resonator cells is a controllable cell (100) which further comprises a control element (120), the control element (120) having an active control component (125) that is operable to adjust the impedance of the primary resonator (110) of the controllable cell (100) in response to a control signal; wherein: the control element (120) comprises a secondary resonator, the secondary resonator is inductively coupled to the primary resonator (110), and the active control component (125) is arranged to vary the electrical properties of the secondary resonator in response to the control signal.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: February 23, 2021
    Assignee: Oxford University Innovation Ltd.
    Inventors: Christopher Stevens, Ekaterina Shamonina, Jan Paszkiewicz
  • Functional material including metal-organic framework, method of preparing the same, and photochemical sensor including the same
    Patent number: 10914681
    Abstract: A functional material includes a porous metal-organic framework (MOF) including an organic ligand derived from benzenedicarboxylic acid and a metal ion cluster coordination-bonded with the organic ligand, and a luminescent molecule in pores of the MOF.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: February 9, 2021
    Assignees: Samsung Electronics Co., Ltd., OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Ha Jin Kim, In Taek Han, Abhijeet K. Chaudhari, Jin-Chong Tan
  • Smart cells and control methods and systems
    Patent number: 10910859
    Abstract: A smart cell, comprising: a positive terminal; a negative terminal; a switching circuit which is arranged to select between a first switching state in which an energy storage device is connected between the positive terminal and the negative terminal and a second switching state in which bypasses said energy storage device; and an inductor provided between the positive terminal and the negative terminal. The inductor provides a means by which to monitor current changes in the rest of the circuit. The inductor can thus be used to detect current changes as seen by the smart cell and this sensed information can be used to control the smart cell, e.g. to control an energy source (energy storage device) that forms part of the smart cell. As the inductor is part of the smart cell, it forms part of a decentralized controller strategy to regulate the state of charge of cells within a larger system.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: February 2, 2021
    Assignee: OXFORD UNIVERSITY INNOVATION LTD
    Inventors: Damien Frost, David Howey
  • Non-invasive prenatal screening
    Patent number: 10900081
    Abstract: The present invention is concerned with prenatal screening and in particular non-invasive prenatal screening, as well as primers, primer sets and kits. In one instance, the invention provides a method of prenatal screening comprising: (a) amplifying a region encompassing the site of a mutation site responsible for the disorder, the amplification being performed on a DNA sample obtained from a pregnant female which comprises both maternal and fetal DNA; (b) sequencing a plurality of products from the amplification and determining whether or not the mutant allele is represented at a different frequency to that expected from the genotype of the pregnant female alone.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: January 26, 2021
    Assignee: Oxford University Innovation Limited
    Inventors: Anna Schuh, Shirley Jane Henderson
  • Process for producing a metal oxide powder
    Patent number: 10889507
    Abstract: A process for producing a metal oxide powder comprising: providing a precursor solution or dispersion containing a metal complex; spraying the precursor solution on to a heated substrate in the presence of water, thereby depositing material on the substrate; drying the deposited material; and removing the deposited material from the substrate to produce the metal oxide powder.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: January 12, 2021
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Peter Edwards, Jonathan Dilworth, Vladimir Kuznetsov, Catherine Hayes
  • Peptide ligase and use thereof
    Patent number: 10889622
    Abstract: The present invention relates to a polypeptide that is capable of promoting the covalent conjugation of two peptide tags or linkers and in particular to a polypeptide comprising: a) an amino acid sequence as set forth in SEQ ID NO: 1; or b) an amino acid sequence with at least 80% sequence identity to a sequence as set forth in SEQ ID NO: 1, wherein said amino acid sequence comprises a glutamic acid at position 61 and one or more of the following: 1) proline at position 66; 2) proline at position 95; 3) glycine at position 96; and 4) valine at position 97, wherein the specified amino acid residues are at positions equivalent to the positions in SEQ ID NO: 1 and wherein said polypeptide is capable of promoting the formation of an isopeptide bond between the lysine residue at position 9 of SEQ ID NO: 2 and the asparagine residue at position 17 of SEQ ID NO: 3.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: January 12, 2021
    Assignee: Oxford University Innovation Limited
    Inventors: Mark Howarth, Can M. Buldun
  • Catalyst comprising permethylpentalene ligands
    Patent number: 10888854
    Abstract: Catalytic compositions comprising permethylpentalene based metallocene complexes supported on solid methylaluminoxane are disclosed. The compositions are effective catalysts/initiators in the polymerisation of olefins. Also disclosed are uses of the compositions in olefin polymerisation.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: January 12, 2021
    Assignee: Oxford University Innovation Limited
    Inventors: Dermot O'Hare, Jean-Charles Buffet, Zoe Turner, Duncan Fraser
  • TREATMENT OF UNIPOLAR DEPRESSIVE DISORDER
    Publication number: 20210000803
    Abstract: The invention relates to the treatment or control of unipolar depressive disorder by administering a compound of Formula I or a salt thereof to a subject; wherein: E is S or Se; R1 and R2 are optional substituents, and are at each occurrence independently selected from: (1) a halogen, which is preferably selected from F, Cl and Br; (2) C1-C4 alkyl, such as C1-C2 alkyl or C1 alkyl, optionally substituted with one or more halogen atoms, each of which is preferably selected from F, Cl and Br; and (3) C1-C4 alkoxy, such as C1-C2 alkoxy or C1 alkoxy; optionally substituted with one or more halogen atoms, each of which is preferably selected from F, Cl and Br; m is an integer in the range of from 0 to 5; and n is an integer in the range of from 0 to 4.
    Type: Application
    Filed: October 26, 2018
    Publication date: January 7, 2021
    Applicant: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Trevor SHARP, Philip COWEN, Grant CHURCHILL
  • POLYMER ADJUVANT
    Publication number: 20210000934
    Abstract: The invention relates to an adjuvant comprising Pattern Recognition Receptor (PRR) agonist molecules linked to polymer chains that are capable of undergoing particle formation in aqueous conditions, or in aqueous conditions in response to external stimuli; and methods of treatment or prevention of disease using such an adjuvant.
    Type: Application
    Filed: June 22, 2020
    Publication date: January 7, 2021
    Applicants: Oxford University Innovation Limited, The U.S.A., as Represented by the Secretary, Department of Health and Human Services
    Inventors: Kerry Fisher, Richard Laga, Geoffrey Lynn, Leonard Seymour, Robert Seder
  • Medical imaging
    Patent number: 10884090
    Abstract: The present invention relates to methods of assessing or obtaining an indication of the presence of a cognitive disorder by analysing microstructural changes in regions of the brain. The invention particularly relates to methods of assessing or obtaining an indication of the presence of types of dementia, for example Alzheimer's disease, by analysing changes in minicolumns in regions or layers of the cortex of the brain or of the whole brain.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: January 5, 2021
    Assignee: Oxford University Innovation Limited
    Inventors: Steven Chance, Rebecca McKavanagh, Mark Jenkinson, Karla Miller
  • METHOD FOR SEQUENCING A HETEROPOLYMERIC TARGET NUCLEIC ACID SEQUENCE
    Publication number: 20200407785
    Abstract: The invention relates to a method for sequencing a heteropolymeric target nucleic acid sequence that involves stochastic sensing. The invention also relates to a method for improving a pore for sequencing a target nucleic acid sequence by modifying one or more sites in the pore.
    Type: Application
    Filed: April 27, 2020
    Publication date: December 31, 2020
    Applicant: Oxford University Innovation Limited
    Inventors: David Jackson Stoddart, Andrew John Heron, Giovanni Maglia, John Hagan Pryce Bayley
  • Method of detecting the presence or absence of autoantibodies
    Patent number: 10877033
    Abstract: The invention relates to methods of detecting the presence or absence of autoantibodies in an individual and to related methods and kits. In particular, the disclosure concerns measuring from one or more samples from an individual suspected of having a disease with an autoimmune component for binding of one or more autoantibodies to membrane vesicles comprising corresponding one or more antigens.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: December 29, 2020
    Assignee: Oxford University Innovation Limited
    Inventors: Angela Vincent, Patrick Joseph Waters, Alexandru Radu Aricescu