Patents Assigned to Paul Scherrer Institut
  • Patent number: 8766198
    Abstract: A single photon counting pixel detector chip has a negligible dead time and consequentially high frame rates. The detector chip contains: a) a layer of photosensitive material; b) an N×M array of photo-detector diodes arranged in the layer of photosensitive material; and c) a N×M array of readout unit cells. The readout unit cell contains an input interface connected to a diode output interface, a high-gain charge to voltage amplifying device and a pixel counter being connected to an output of the high-gain voltage amplifying device. The pixel counter is split into a first number of nibble counters. The basic counter cell contains a counting element, a switch, a temporary storage element and an output stage. Additionally, the detector chip has a side shift register to read out the nibble counters row-wise with a predetermined number of nibble row selections.
    Type: Grant
    Filed: December 9, 2010
    Date of Patent: July 1, 2014
    Assignee: Paul Scherrer Institut
    Inventors: Roberto Dinapoli, Beat Henrich, Roland Horisberger
  • Publication number: 20140166861
    Abstract: A single photon counting detector system has a layer of photosensitive material and an N×M array of photo-detector diodes. Each photo-detector diode has a bias potential interface and a diode output interface. The bias potential interface is connected to bias potential. An N×M array of high gain, low noise readout unit cells is provided, one readout unit cell for each photo-detector diode. Each readout unit cell has an input interface connected to the diode output interface, a high-gain voltage amplifier with an integration capacitor at least two parallel lines of digital counters, each having a comparator with an individually selectable threshold and a gateable section to determine the counting intervals of the digital counters. A multiplexer allows access to the readout cell unit either on a per pixel basis or for several pixels in parallel to read out the digital counter to a data processor transferring the data off chip.
    Type: Application
    Filed: December 29, 2011
    Publication date: June 19, 2014
    Applicant: PAUL SCHERRER INSTITUT
    Inventors: Bernd Schmitt, Anna Bergamaschi, Aldo Mozzanica, Roberto Dinapoli
  • Publication number: 20140169698
    Abstract: An image fusion method combines absorption, differential phase contrast and dark-field (scattering) signals obtained with X-ray phase contrast sensitive techniques, such as an arrangement of gratings. The process fuses the absorption and dark-field signals by principal component analysis. Further the differential phase contrast is merged into the PCA fused image to obtain an edge enhancement effect. Due to its general applicability and its simplicity in usage, the proposed process is usable as a standard method for image fusion scheme using phase contrast imaging, in particular on medical scanners (for instance mammography), inspection at industrial production lines, non-destructive testing, and homeland security.
    Type: Application
    Filed: July 20, 2012
    Publication date: June 19, 2014
    Applicant: PAUL SCHERRER INSTITUT
    Inventors: Marco Stampanoni, Zhentian Wang
  • Publication number: 20140112440
    Abstract: An X-ray arrangement is suitable to record absorption, phase contrast, and dark field images of an object. The visibility of low absorbing specimens is improved and required radiation dose is reduced. The assembly includes an X-ray source; two or more gratings; a position-sensitive detector with spatially modulated detection sensitivity; a recorder for recording the images; an evaluator for evaluating the intensities for each pixel to identify the characteristic of the object for each individual pixel as an absorption and/or a differential phase contrast and/or an x-ray scattering dominated pixel. Images are collected by rotating from 0 to n or 2n either the sample or the assembly. The gratings are produced with planar geometry. The X-rays pass through the gratings parallel to the substrate. The grating structures extend along the X-ray path which determines the phase shift.
    Type: Application
    Filed: April 4, 2011
    Publication date: April 24, 2014
    Applicant: PAUL SCHERRER INSTITUT
    Inventors: Christian David, Marco Stampanoni
  • Patent number: 8704201
    Abstract: An energy filter allows, particularly at lower beam energies, a determined spread of the beam energies in order to preserve the beam edges and to spread the Bragg peak at each individual beam energy. The energy filter behaves similarly to a ridge filter and spreads out the Bragg peak of a low energy proton beam (70-100 MeV) so that energy modulation of the beam can be done with steps of 5 mm in one go over the full range of 235-70 MeV. Due to its mechanical flexibility, the energy filter can be placed on the skin of the patient which minimizes the effect of scattering in the filter due to the short distance behind a layer of a plurality of metal particles within a flexible soft plastic sheet to the skin of the patient.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: April 22, 2014
    Assignee: Paul Scherrer Institut
    Inventor: Jacobus Maarten Schippers
  • Publication number: 20130329231
    Abstract: A laser interferometer and a method for operating a laser interferometer perform a differential position measurement by laser interferometry of two elements while offering a rotational degree of freedom to one of the elements using a reflecting sphere as a mirror for the laser beam. The laser interferometer and method do not require the object to be aligned with the rotation axis, but instead can track the object in off-centered geometries. This is achieved by employing the pointing of the reflected beam from the sphere as a feedback signal to realign the interferometer which then has a constant beam pointing to the center of the sphere in all cases. The laser interferometer and method keep the direction of the measurement constant. The laser interferometer and method are suitable for homodyne and heterodyne types of laser interferometer technology.
    Type: Application
    Filed: November 11, 2011
    Publication date: December 12, 2013
    Applicant: PAUL SCHERRER INSTITUT
    Inventors: Mirko Holler, Jörg Raabe
  • Patent number: 8535840
    Abstract: A self-contained system for the generation of electrical energy from biomass by gasification combines several process units in one self-contained system. The global properties are greater than the sum of the individual properties of the process units.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: September 17, 2013
    Assignee: Paul Scherrer Institut
    Inventors: Serge Biollaz, Markus Jenne, Florian Nagel, Tilman J. Schildhauer
  • Patent number: 8475549
    Abstract: To generate methane from biomass, a biomass pulp is produced from the biomass with a desired dry mass content being set, and the biomass pulp is placed under pressure. The biomass pulp is heated under pressure in order to liquefy the solid organic components of the biomass pulp. The pressurized and heated biomass pulp is heated further to at least the critical temperature of the biomass pulp. Solids precipitated under pressure and increased temperature are separated from the fluid phase. At least a part of the remaining fluid phase is gasified under pressure and increased temperature by means of a reactor to form a methane-rich gas.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: July 2, 2013
    Assignee: Paul Scherrer Institut
    Inventors: Frederic Vogel, Samuel Stucki, Thanh-Binh Truong, Maurice H. Waldner
  • Patent number: 8461559
    Abstract: A method for evaluating radiation model data in particle beam radiation applications, in particular in proton beam therapy of a determined target volume of malignant tissue within a patient, includes the following steps: a) gaining diagnostic data for a determined target volume to be irradiated; b) calculating a particle range in the predetermined target volume based on the diagnostic data for the determined target volume; c) designing a radiation model with particle beam characteristics based on the calculated particle range and optionally on a calculated dose depth distribution; d) applying a single pencil beam shot to the determined target volume at an elevated beam energy as compared to the particle beam characteristics of the radiation model; e) measuring the beam range of the single pencil beam shot downstream of the determined target volume; and f) comparing the measured beam range to a reference beam range calculated on the basis of the radiation model.
    Type: Grant
    Filed: January 8, 2010
    Date of Patent: June 11, 2013
    Assignee: Paul Scherrer Institut
    Inventor: Antony Lomax
  • Publication number: 20130137915
    Abstract: An energy filter allows, particularly at lower beam energies, a determined spread of the beam energies in order to preserve the beam edges and to spread the Bragg peak at each individual beam energy. The energy filter behaves similarly to a ridge filter and spreads out the Bragg peak of a low energy proton beam (70-100 MeV) so that energy modulation of the beam can be done with steps of 5 mm in one go over the full range of 235-70 MeV. Due to its mechanical flexibility, the energy filter can be placed on the skin of the patient which minimizes the effect of scattering in the filter due to the short distance behind a layer of a plurality of metal particles within a flexible soft plastic sheet to the skin of the patient.
    Type: Application
    Filed: November 16, 2010
    Publication date: May 30, 2013
    Applicant: PAUL SCHERRER INSTITUT
    Inventor: Jacobus Maarten Schippers
  • Patent number: 8450047
    Abstract: A method is provided for achieving specific magnetic states with a given vortex chirality in artificial kagome spin ice building block structures containing one or more hexagonal rings of ferromagnetic islands created with electron beam lithography, where a subgroup of the ferromagnetic islands have a smaller width and therefore higher switching field than the other normal (wider) islands and are placed at specific positions in each of the rings. The positioning of the islands determines the magnetic state of the building block structure during magnetization reversal, and determines the chirality of the magnetic vortices that occur in each ring.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: May 28, 2013
    Assignee: Paul Scherrer Institut
    Inventors: Laura Heyderman, Elena Mengotti, Danilo Zanin, Rajesh Chopdekar, Hans-Benjamin Braun, Remo Huegli, Gerard Duff
  • Patent number: 8415086
    Abstract: A method is provided for achieving low energy states for the study of chirality kagome spin ice structures, the method having the steps of providing a silicon substrate; spin coating a polymethyl acrylate resist on said silicon substrate; providing an electron beam writer; exposing said coated substrate to an electron beam from said electron beam writer; positioning more than one thin island ferromagnetic island structure along a honeycomb lattice of said kagome spin ice component, wherein said positioning being along a determined magnetization direction of said lattice and wherein said island structures providing a mechanism in which chirality is controlled.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: April 9, 2013
    Assignee: Paul Scherrer Institut
    Inventors: Laura Heyderman, Elena Mengotti, Danilo Zanin, Rajesh Chopdekar, Hans-Benjamin Braun, Remo Hügli, Gerard Duff
  • Patent number: 8397576
    Abstract: A pressure of a fluid is determined in a vacuum-tight welded housing containing a first membrane enclosing a part of a first inner volume and having a first contact area associated with a first temperature sensor and a heater. A second membrane opposite the first contact area also encloses part of the first inner volume and has a second contact area associated with a second temperature sensor. The first or second membrane is elastic around the contact area. The membranes hermetically seal a second inner volume at a reference pressure. The contact areas determine the mechanical and thermal contact due to the elasticity of one of the membranes when the first inner volume is connected to the fluid. When the volume is connected to the fluid F, the intensity and/or the time gradient of the heat transfer from the first to the second contact area is measured.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: March 19, 2013
    Assignee: Paul Scherrer Institut
    Inventor: Knud Thomsen
  • Patent number: 8383575
    Abstract: A complex comprising barnase bound with high affinity to barstar, and comprising a therapeutic and/or diagnostic agent bound to barnase and/or barstar.
    Type: Grant
    Filed: January 31, 2005
    Date of Patent: February 26, 2013
    Assignee: Paul Scherrer Institut
    Inventors: Sergey Deyev, Robert Waibel, Andreas Plueckthun
  • Patent number: 8374309
    Abstract: An arrangement and a method are disclosed for projective and/or tomographic phase-contrast imaging using X-ray radiation. In at least one embodiment, one or more phase grids is/are arranged in the beam path such that during a rotation of the at least one X-ray source, the examination object is scanned with different spatial orientations of the grid lines relative to the examination object such that the complete refraction angle, and hence the complete phase shift gradient, can be determined for each X-ray beam from the two scans with differently oriented phase grids in order to be able to show the phase shift of an examination object in terms of projections or in a tomographic image.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: February 12, 2013
    Assignees: Siemens Aktiengesellschaft, Paul Scherrer Institut
    Inventors: Tilman Donath, Martin Hoheisel, Christian David, Eckhard Hempel, Franz Pfeiffer, Stefan Popescu
  • Publication number: 20120298877
    Abstract: A single photon counting pixel detector chip has a negligible dead time and consequentially high frame rates. The detector chip contains: a) a layer of photosensitive material; b) an N×M array of photo-detector diodes arranged in the layer of photosensitive material; and c) a N×M array of readout unit cells. The readout unit cell contains an input interface connected to a diode output interface, a high-gain charge to voltage amplifying device and a pixel counter being connected to an output of the high-gain voltage amplifying device. The pixel counter is split into a first number of nibble counters. The basic counter cell contains a counting element, a switch, a temporary storage element and an output stage. Additionally, the detector chip has a side shift register to read out the nibble counters row-wise with a predetermined number of nibble row selections.
    Type: Application
    Filed: December 9, 2010
    Publication date: November 29, 2012
    Applicant: PAUL SCHERRER INSTITUT
    Inventors: Roberto Dinapoli, Beat Henrich, Roland Horisberger
  • Patent number: 8313544
    Abstract: In a process for the synthetic generation of methane from a feed gas mixture, a feed gas mixture including carbon monoxide, hydrogen, water vapor, CO2, volatile hydrocarbons comprising C2 and higher, unsaturated C2 components and aromatic hydrocarbons in the range of 1 to 10 vol % is provided. The feed gas mixture is contacted with a fluidized bed catalyst having catalyst particles having a catalytic active component selected from the group consisting of a metal, a metal compound and combinations thereof. The contacting occurs at an elevated temperature in the range of 250 to 450° C., a feed gas pressure in the range of 0.8 to 70 bar, a gas hourly space velocity of 1000 to 50000 h?1, and a concentration of H2/CO in the gas mixture in the range of 0.25 to 5.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: November 20, 2012
    Assignee: Paul Scherrer Institut
    Inventors: Martin Seemann, Serge Biollaz, Samuel Stucki
  • Patent number: 8309275
    Abstract: A method for preparing a membrane to be assembled in a membrane, electrode assembly includes the step of swelling an ion-conducting membrane in a liquid containing at least one solvent or to an atmosphere containing the vapor phase of at least one solvent by controlling the content of the solvent in the ion-conducting membrane. A method for manufacturing a membrane electrode assembly using an ion conducting membrane includes the steps of: providing an ion-conducting membrane in a pre-swollen state; coating the ion-conducting membrane on both sides with an electrode layer to form a sandwich; and hot-pressing the sandwich to form an ion-conducting bonding of the layers of the sandwich. Furthermore, a membrane electrode assembly is disclosed including a hot pressed sandwich having an electrode layer, a ion-conducting membrane and again an electrode layer, thereby using the ion-conducting membrane in its pre-swollen status prior to the hot-pressing.
    Type: Grant
    Filed: September 14, 2004
    Date of Patent: November 13, 2012
    Assignee: Paul Scherrer Institut
    Inventors: Hans-Peter Brack, Günther Scherer, Lorenz Gubler
  • Publication number: 20120189964
    Abstract: A method is provided for achieving specific magnetic states with a given vortex chirality in artificial kagome spin ice building block structures containing one or more hexagonal rings of ferromagnetic islands created with electron beam lithography, where a subgroup of the ferromagnetic islands have a smaller width and therefore higher switching field than the other normal (wider) islands and are placed at specific positions in each of the rings. The positioning of the islands determines the magnetic state of the building block structure during magnetization reversal, and determines the chirality of the magnetic vortices that occur in each ring.
    Type: Application
    Filed: February 24, 2012
    Publication date: July 26, 2012
    Applicant: PAUL SCHERRER INSTITUT
    Inventors: Laura Heyderman, Elena Mengotti, Danilo Zanin, Rajesh Chopdekar, Hans-Benjamin Braun, Remo Huegli, Gerard Duff
  • Patent number: 8228044
    Abstract: A supercapacitors voltage balancing device (2) to be connected to a supercapacitor module (1) having N individual supercapacitors (10) connected in series, for optimizing the voltage of the individual supercapacitors in the module.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: July 24, 2012
    Assignees: Conception et Developpement Michelin S.A., Paul Scherrer Institut
    Inventors: Rüdiger Kötz, Jean-Claude Sauter