Patents Assigned to Pulse
  • Patent number: 11326908
    Abstract: An apparatus for measuring wire and cable length is provided for using a wireless encoder for wire and cable processing. The apparatus for measuring wire and cable length may include a housing, battery, communication component, microcontroller, printed circuit board, encoder module, encoder disc, shaft, wire counter and spool.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: May 10, 2022
    Assignee: Wire Pulse, Inc.
    Inventors: Andrew F. Human, Eric M. Martin
  • Publication number: 20220134087
    Abstract: A handheld, therapeutic electrode and connector that are compatible with high voltages from a pulse generator are disclosed. The electrode includes therapeutic terminals on a tip configured to deliver high voltage pulses safely to a patient. The electrode includes sleeves, bosses, wiring channels, and other features that maximize a minimum clearance distance (across non-conductive surfaces) and air clearance between conductive connectors themselves or the connectors and a user, thus preventing dangerous arcing. Internal surfaces and seams are taken into account. The connector and its mating outlet can include similar features to maximize clearance distance. Skirts, skirt holes, and finger stops are also employed, and they can be on either the connector or outlet, or the tip or handle of the electrode.
    Type: Application
    Filed: January 13, 2022
    Publication date: May 5, 2022
    Applicant: Pulse Biosciences, Inc.
    Inventors: Mark P. Kreis, David J. Danitz, Cameron D. Hinman, Sean N. Finson
  • Patent number: 11311721
    Abstract: Methods and apparatuses for treating a tissue with an electric treatment by rotating a pattern of electrodes partway through a treatment is disclosed. Also described herein are methods and apparatuses to treat tissue, including treating skin disorders, by selectively de-nucleating epidermal cells without provoking a significant inflammatory response, e.g., without increasing the density of leukocytes in the treated skin, and without affecting the non-cellular components of the dermis.
    Type: Grant
    Filed: October 8, 2020
    Date of Patent: April 26, 2022
    Assignee: Pulse Biosciences, Inc.
    Inventors: Edward Ebbers, David J. Danitz, Richard L. Nuccitelli, Darrin R. Uecker, Cameron D. Hinman, Kevin L. Moss
  • Publication number: 20220083179
    Abstract: A system and method are presented showing an improved computer user interface and a method for constructing that interface.
    Type: Application
    Filed: August 11, 2021
    Publication date: March 17, 2022
    Applicant: Pulse-iQ, Inc.
    Inventors: Jerry Rassamni, Nathaniel James Rassamni
  • Patent number: 11253695
    Abstract: A handheld, therapeutic electrode and connector that are compatible with high voltages from a pulse generator are disclosed. The electrode includes therapeutic terminals on a tip configured to deliver high voltage pulses safely to a patient. The electrode includes sleeves, bosses, wiring channels, and other features that maximize a minimum clearance distance (across non-conductive surfaces) and air clearance between conductive connectors themselves or the connectors and a user, thus preventing dangerous arcing. Internal surfaces and seams are taken into account. The connector and its mating outlet can include similar features to maximize clearance distance. Skirts, skirt holes, and finger stops are also employed, and they can be on either the connector or outlet, or the tip or handle of the electrode.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: February 22, 2022
    Assignee: PULSE BIOSCIENCES, INC.
    Inventors: Mark P. Kreis, David J. Danitz, Cameron D. Hinman, Sean N. Finson
  • Patent number: 11213692
    Abstract: A PEMF web using immersive, flux-guided, micro-coils to direct intense, deeply penetrating, magnetic flux into a subject from each micro-coil capable of pointing in an arbitrary direction. Micro-coils are spooled around iron cores, insulated properly, and soldered to connecting wires, all embedded in a polymeric resin, such as cold-cured silicone resin. Nodes protect, enclose, insulate electrically, and otherwise protect the micro-coils. Connectors between nodes provide mechanical stability against breaking of wires, while permitting folding, bending, buckling, and otherwise deflecting to position the nodes as desired with three degrees of freedom.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: January 4, 2022
    Assignee: PULSE, LLC
    Inventors: Gregory S. Anderson, Kade E. Huntsman, Dale C. Gledhill, Douglas R. Burrell
  • Patent number: 11201384
    Abstract: In-building antenna apparatus and methods for manufacturing and installing the same. In one embodiment, the antenna apparatus includes a radome cover, a lower flange, an antenna housing, a spring-loaded mount apparatus, a signaling interface, and a plurality of spring arms. Each of the spring arms may include at least one tie-down location. Accordingly, when a removable tie is placed around a plurality of tie-down locations, the antenna apparatus resides in an installation configuration; however, when the removable tie is removed from around the plurality of tie-down locations, the antenna apparatus transitions towards a default configuration. The spring arms may also act as a ground plane for the antenna. Spring-loaded mount apparatus as well as methods of manufacturing and installing the aforementioned antenna apparatus are also disclosed.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: December 14, 2021
    Assignee: Pulse Finland OY
    Inventors: Zack Ge, Jay Yuan
  • Patent number: 11191975
    Abstract: An erythrocyte de-aggregation system includes a band, including a strap and housing securing an iron-cored, micro-coil to an appendage, such as a wrist, of a subject to apply a PEMF into a target vessel in the vascular system of the subject. Typically, all of the blood circulates about the body within a matter of a few minutes, some within seconds, thus treating the entire bloodstream over time. The portable PEMF system intensifies both the concentration of electromagnetic flux per unit area, as well as the depth of penetration into the body. The portable PEMF systems relies on the body's circulatory system to eventually pass the body's entire volume of blood past it over a period of time.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: December 7, 2021
    Assignee: Pulse, LLC
    Inventors: Gregory S. Anderson, Kade E. Huntsman, Dale C. Gledhill, Marc E. Jackson
  • Patent number: 11188104
    Abstract: An electronic thermostat replaces an electro-mechanical thermostat and is located in a different location from the blower motor it controls. The electronic thermostat controls the blower motor on the same wires from which the thermostat receives power. The safe, low voltage power supply that powers the electronic thermostat is located at the blower motor location and is housed in the Blower Motor Module (BMM). This configuration has the advantage that it removes a bulky and space consuming component from the thermostat, the A/C transformer. This also reduces the amount of power (heat) dissipated by the electronic thermostat power supply, thus reducing a source of potential temperature measurement inaccuracies. Also, removing the 120 VAC power from the thermostat and replacing it with an isolated low voltage source increases safety.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: November 30, 2021
    Assignee: PULSE IQ LLC
    Inventors: Angel P. Bezos, Emilio A. Fernandez
  • Publication number: 20210345889
    Abstract: A blood vessel cross-section function, a blood vessel pressure difference, and blood vessel stress may be established. A method for establishing a blood vessel cross-section function may include: obtaining image data in at least one cardiac cycle; selecting multiple feature times during the one cardiac cycle; generating spatial models of a target region blood vessel corresponding to each of the feature times according to the image data; establishing a first cross-section model of the target region blood vessel at each position along an axial direction of the target region blood vessel according to each of the spatial models; and establishing a corresponding first cross-section function according to each first cross-section model. Actual conditions of blood vessels may be reflected more accurately, and may provide an intermediate variable with less error for subsequent analysis operations, so that the later calculated value is closer to the actual value.
    Type: Application
    Filed: February 28, 2019
    Publication date: November 11, 2021
    Applicant: PULSE MEDICAL IMAGING TECHNOLOGY (SHANGHAI) CO. LTD.
    Inventors: Shengxian TU, Jiayue HUANG, Jingfeng HAN
  • Patent number: 11167125
    Abstract: Described herein are treatment tip apparatuses (e.g., devices, systems, etc.) including one, or more preferably a plurality, of electrodes that are protected by an electrode partition, such as an electrode housing (which may be retractable) until pressed against the tissue for deployment of the electrodes and delivery of a therapeutic treatment. In particular, these apparatuses may include a plurality of treatment electrodes (e.g., needle electrodes) and be configured for the delivery of nanosecond pulsed electric fields.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: November 9, 2021
    Assignee: PULSE BIOSCIENCES, INC.
    Inventors: Kevin L. Moss, Christopher J. Foster, Cameron D. Hinman, David J. Danitz, Darrin R. Uecker
  • Publication number: 20210298706
    Abstract: The present invention relates to a blood vessel image processing method, a blood vessel image processing apparatus, a computer storage medium, and an imaging device. The method includes: obtaining blood vessel geometric structure information of a blood vessel segment of interest; obtaining vital feature information of the blood vessel segment; establishing an association relationship between the blood vessel geometric structure information and the vital feature information; and displaying the blood vessel geometric structure information and the vital feature information in the same image in a mutual fusion manner by using the association relationship as a reference. In this way, work efficiency of users can be improved by the solution.
    Type: Application
    Filed: September 3, 2018
    Publication date: September 30, 2021
    Applicant: PULSE MEDICAL IMAGING TECHNOLOGY (SHANGHAI) CO. LTD.
    Inventors: Shengxian TU, Wei YU, Jiayue HUANG, Su ZHANG, Xiaogang FU
  • Patent number: 11064897
    Abstract: A method for computing fractional flow reserve (FFR), including receiving geometrical parameters of a blood vessel segment including a proximal end and a distal end, the geometrical parameters including a first geometrical parameter, a second geometrical parameter and a third geometrical parameter; and with the proximal end as a reference point, deriving a reference lumen diameter function and a geometrical parameter difference function based on the geometrical parameters and the distance from the position along the segment of blood vessel to the reference point. Derivatives of the geometrical parameter difference function are calculated in multiple scales. FFR is computed as a ratio of a second blood flow pressure at the first location of the blood vessel to a first blood flow pressure at the proximal end of the segment based on the multiple scales of derivative difference functions and the maximum mean blood flow velocity.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: July 20, 2021
    Assignee: PULSE MEDICAL IMAGING TECHNOLOGY (SHANGHAI) CO., LTD
    Inventors: Shengxian Tu, Miao Chu, Bing Liu, Yazhu Chen
  • Patent number: 11051882
    Abstract: A sub-microsecond pulsed electric field generator is disclosed. The field generator includes a controller, which generates a power supply control signal and generates a pulse generator control signal, and a power supply, which receives the power supply control signal and generates one or more power voltages based on the received power supply control signal. The field generator also includes a pulse generator which receives the power voltages and the pulse generator control signal, and generates one or more pulses based on the power voltages and based on the pulse generator control signal. In some embodiments, the controller receives feedback signals representing a value of a characteristic of or a result of the pulses and generates at least one of the power supply control signal and the pulse generator control signal based on the received feedback signals.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: July 6, 2021
    Assignee: Pulse Biosciences, Inc.
    Inventors: Shu Xiao, Brian G. Athos, Mark P. Kreis, David J. Danitz, Darrin R. Uecker
  • Patent number: 11051871
    Abstract: Nanosecond pulsed electric field (nsPEF) treatments of a tumor are adjusted based on a size and type of the tumor to stimulate an immune response against the tumor and other tumors in the subject. Calreticulin expression on tumor cells can be detected to confirm treatment. An immune response biomarker can be measured, and further nsPEF treatments can be performed if needed to stimulate or further stimulate the immune response. Cancers that have metastasized may be treated by directly treating a tumor that is most accessible. The treatment can be combined with CD47-blocking antibodies, doxorubicin, CTLA-4-blocking antibodies, and/or PD-1-blocking antibodies. Electrical characteristics of nsPEF treatments can be based on the size, type, and/or strength of tumors and/or a quantity of tumors in the subject.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: July 6, 2021
    Assignee: Pulse Biosciences, Inc.
    Inventors: Richard Lee Nuccitelli, Pamela S. Nuccitelli, Joanne Lum, Kaying Lui, Brian G. Athos, Mark P. Kreis, Zachary R. Mallon, Jon Berridge
  • Publication number: 20210196375
    Abstract: A sub-microsecond pulsed electric field generator is disclosed. The field generator includes a controller, which generates a power supply control signal and generates a pulse generator control signal, and a power supply, which receives the power supply control signal and generates one or more power voltages based on the received power supply control signal. The field generator also includes a pulse generator which receives the power voltages and the pulse generator control signal, and generates one or more pulses based on the power voltages and based on the pulse generator control signal. In some embodiments, the controller receives feedback signals representing a value of a characteristic of or a result of the pulses and generates at least one of the power supply control signal and the pulse generator control signal based on the received feedback signals.
    Type: Application
    Filed: March 9, 2021
    Publication date: July 1, 2021
    Applicant: Pulse Biosciences, Inc.
    Inventors: Shu Xiao, Brian G. Athos, Mark P. Kreis, David J. Danitz, Darrin R. Uecker
  • Publication number: 20210146129
    Abstract: A pulse generation system is disclosed. The pulse generation system includes a controller, an output terminal, and a plurality of pulse generator circuits. The controller is configured to cause a driving signal pulse to be transmitted to any selected one or more of the pulse generator circuits, and to cause the driving signal pulse to not be transmitted to any selected one or more other pulse generator circuits. Each of the pulse generator circuits is configured to generate an output voltage pulse at the output terminal in response to the driving signal pulse being transmitted thereto.
    Type: Application
    Filed: January 26, 2021
    Publication date: May 20, 2021
    Applicant: Pulse Biosciences, Inc.
    Inventors: Brian G. Athos, Shu Xiao, David J. Danitz, Mark P. Kreis, Darrin R. Uecker
  • Patent number: 11000589
    Abstract: Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one aspect, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: May 11, 2021
    Assignee: Pulse Therapeutics, Inc.
    Inventor: Francis M. Creighton
  • Patent number: 10955580
    Abstract: Tools and methods for measuring resistivity are provided. The tool for measuring resistivity in a formation comprises a receiver module comprising a first electromagnetic signal receiver and a second electromagnetic signal receiver; a first electromagnetic signal transmitter removably coupled to one longitudinal end of the receiver module; a second electromagnetic signal transmitter removably coupled to the other longitudinal end of the receiver module; and each of the first and the second electromagnetic signal receivers configured to receive electromagnetic signals propagating in the formation from the first and the second electromagnetic signal transmitters.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: March 23, 2021
    Assignee: Pulse Directional Technologies Inc.
    Inventors: Karl Edler, Steve Braisher
  • Patent number: D938464
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: December 14, 2021
    Assignee: Pulse Medical Imaging Technology (Shanghai) Co. Ltd.
    Inventors: Shengxian Tu, Jun Pu, Xinkai Qu