Patents Assigned to Purdue Research Foundation
  • Patent number: 11047869
    Abstract: The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a tissue sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis. Due to the use of a liquid phase that does not destroy native tissue morphology during analysis, a subsequent staining technique can be performed on the tissue sample and an overlaid image can be produced of a mass spectral image and a staining image.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: June 29, 2021
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Livia Schiavinato Eberlin, Christina Ramires Ferreira, Allison Lisa Dill, Demian R. Ifa
  • Patent number: 11050995
    Abstract: A method for generating encoded depth data includes receiving digital fringe projection (DFP) data corresponding to a three-dimensional structure of a physical object, and generating first and second fringe encodings for a first predetermined wavelength based on the DFP data at a first coordinate. The method further includes generating third and fourth fringe encodings for a second predetermined wavelength based on the DFP data at the first coordinate, the second wavelength being longer than the first wavelength, and generating a combined fringe encoding based on the third fringe encoding and the fourth fringe encoding. The method further includes storing the first, second, and combined fringe encoding data in a pixel of two-dimensional image data at a pixel coordinate in the two-dimensional image data corresponding to the first coordinate.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: June 29, 2021
    Assignee: Purdue Research Foundation
    Inventors: Song Zhang, Tyler Bell
  • Patent number: 11047024
    Abstract: A high-strength aluminum alloy coating. The coating includes aluminum, 9R phase, fine grains, nanotwins, stacking faults, and a solute capable of stabilizing the 9R phase, the fine grains, and the stacking faults. A method of making a high-strength aluminum alloy coating on a substrate. The method includes, depositing the constituents of an aluminum alloy on a substrate such that the deposit forms a high-strength aluminum alloy coating containing 9R phase, fine grains, nanotwins, and stacking faults. A high-strength deformation layer in and on a casting of an aluminum alloy containing 9R phase, fine grains, nanotwins, stacking faults, and a solute capable of stabilizing the PR phase, the fine grains, and the stacking faults. A method of making a high-strength deformation layer in and on a casting of an aluminum alloy by deforming the alloy such that deformation layer contains 9R phase, fine grains, nanotwins, and stacking faults.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: June 29, 2021
    Assignee: Purdue Research Foundation
    Inventors: Xinghang Zhang, Qiang Li, Haiyan Wang, Sichuang Xue, Yifan Zhang
  • Patent number: 11045783
    Abstract: The invention generally relates to systems and methods for increasing reaction yield. In certain embodiments, the invention provides systems for increasing a yield of a chemical reaction that include a pneumatic sprayer configured to generate a liquid spray discharge from a solvent. The solvent includes a plurality of molecules, a portion of which react with each other within the liquid spray discharge to form a reaction product. The system also includes a collector positioned to receive the liquid spray discharge including the unreacted molecules and the reaction product. The system also includes a recirculation loop connected from the collector to the pneumatic sprayer in order to allow the unreacted molecules and the reaction product to be recycled through the pneumatic sprayer, thereby allowing a plurality of the unreacted molecules to react with each other as the unreacted molecules cycle again through the system.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: June 29, 2021
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Michael Stanley Wleklinski, David Logsdon
  • Patent number: 11050058
    Abstract: Method of making interconnected layered porous carbon sheets with porosity within the carbon sheets and in-between the carbon sheets for use as an electrode. Method of making a metal-nanoparticle carbon composite, wherein metal particles are surrounded by shells made of amorphous carbon. Electrodes containing an amorphous carbon structure comprising a plurality of interconnected layered porous carbon sheets. Electrodes containing graphitic carbon structure with a surface area in the range of 5-200 m2/g. Electrodes containing a metal-nanoparticle carbon composite comprising metal core-carbon shell like architecture and an amorphous structure, wherein metal particles are surrounded by shells made of amorphous carbon.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: June 29, 2021
    Assignee: Purdue Research Foundation
    Inventors: Vilas Ganpat Pol, Vinodkumar Etacheri
  • Patent number: 11045676
    Abstract: The present application relates to a novel method for reductive degradation of perfluoroalkyl-containing compounds, such as perfluoroalkyl sulfonates, by activated carbon (AC) supported zero valent iron-nickel nanoparticles (nNi0Fe0).
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: June 29, 2021
    Assignee: Purdue Research Foundation
    Inventors: Linda S Lee, Jenny E Zenobio
  • Patent number: 11050114
    Abstract: Battery enclosure arrangements for a vehicular battery system. The arrangements, capable of impact resistance include plurality of battery cells and a plurality of kinetic energy absorbing elements. The arrangements further include a frame configured to encase the plurality of the kinetic energy absorbing elements and the battery cells. In some arrangements the frame and/or the kinetic energy absorbing elements can be made of topologically interlocked materials.
    Type: Grant
    Filed: August 18, 2019
    Date of Patent: June 29, 2021
    Assignee: Purdue Research Foundation
    Inventors: Waterloo Tsutsui, Yuezhong Feng, Weinong Wayne Chen, Thomas Heinrich Siegmund
  • Publication number: 20210194811
    Abstract: A load balancing method is disclosed, the method includes establishing a processing network including a plurality of task-processing processors interconnected therewith, each processor of the plurality having a queue of tasks to be processed, establishing a k-regular graph including nodes and branches connecting the nodes, where k is the degree of the graph, assigning d walkers to the k-regular graph, where each walker is randomly assigned to a node, receiving a new task to be processed, walking from the assigned nodes to new nodes by randomly choosing a new node from one or more available nodes, without backtracking from each of the assigned nodes to a node from which each of the d walkers immediately walked, comparing the queues of the new nodes, determining which queue of the new nodes has the least number of tasks; and assigning the new task to the node with the least number of tasks.
    Type: Application
    Filed: February 17, 2021
    Publication date: June 24, 2021
    Applicants: Purdue Research Foundation, The Regents of the University of Michigan
    Inventors: Harsha Honnappa, Vijay Subramanian
  • Publication number: 20210190557
    Abstract: A flow measurement apparatus comprising an elongated mounting stem having an inner stem cavity, the mounting stem configured to be mounted in an area of flow to be measured. A probe housing is mounted to an outer surface of the mounting stem and positioned on an upstream side of the mounting stem. The probe housing has a first hole near a center point of the housing and a second, third and fourth hole positioned near the perimeter of the housing. A fifth hole is located on a downstream side of the mounting stem. At least five pressure sensors and a plurality of pressure tapping tubes connecting the holes to the corresponding pressure sensors are included.
    Type: Application
    Filed: October 12, 2018
    Publication date: June 24, 2021
    Applicant: Purdue Research Foundation
    Inventors: Guillermo Paniagua Perez, David Gonzalez Cuadrado, Valeria Andreoli, James Braun, Zhe Liu
  • Publication number: 20210188452
    Abstract: A hydraulic propulsion system is disclosed. The system includes one or more input interfaces configured to receive mechanical power from a power source, four or more variable displacement pumps coupled to the one or more input interfaces adaptable to generate a controlled variable quantity of fluid to be pumped out of each of the variable displacement pumps in response to a control input from a corresponding control interface, and four or more positive displacement motors each fluidly coupled to a corresponding variable displacement pump and configured to receive the pumped fluid, wherein each motor is configured to be mechanically coupled to one or more aerodynamic rotors of a multi-rotor vertical take-off and landing aircraft to control thrust and attitude.
    Type: Application
    Filed: October 8, 2018
    Publication date: June 24, 2021
    Applicant: Purdue Research Foundation
    Inventors: Lizhi SHANG, Monika IVANTYSYNOVA
  • Publication number: 20210195058
    Abstract: Example implementations relate to halftone image creation. An example non-transitory machine-readable medium can include instructions executable to determine a highlight core shape and a shadow core shape of a microcell within a supercell. The instructions can be executable to determine growth sequences for a plurality of pixels within the highlight core and the shadow core and between the microcell and other microcells within the supercell, divide each of the plurality of pixels into a plurality of subpixels, and create a halftone image for an unequal resolution printing device using a constrained direct binary search model and based on the highlight core shape, shadow core shape, growth sequences, and the plurality of subpixels.
    Type: Application
    Filed: January 26, 2018
    Publication date: June 24, 2021
    Applicant: Purdue Research Foundation
    Inventors: Kurt Robert Bengston, Wan-Eih Huang, Tongyang Liu, Jan P Allebach
  • Publication number: 20210187010
    Abstract: Disclosed herein are fully synthetic polymer-based lung surfactant materials, for the first time, as next generation SRT. In vitro studies on these polymer lung surfactants show that the candidate materials effectively mimic the surface tension controlling properties of currently marketed natural lung surfactants. Further, the polymer lung surfactants have strong protein resistance, which makes this class of materials promising also for potential use in Acute Respiratory Distress Syndrome (ARDS) treatment.
    Type: Application
    Filed: November 30, 2020
    Publication date: June 24, 2021
    Applicant: Purdue Research Foundation
    Inventors: You-Yeon Won, Hyun Chang Kim
  • Patent number: 11042019
    Abstract: A method for imaging a sample, wherein the sample changes a polarization state of light as a function of position, wherein the method includes changing a polarization state of a purely polarized light of an incident light striking a micro-retarder array, thereby inducing a changed polarization state of the polarization state. The micro-retarder array is placed in a rear conjugate focal plane of a microscope. The method additionally includes projecting the changed polarization state of the polarization state into an object plane of the microscope containing the sample.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: June 22, 2021
    Assignee: Purdue Research Foundation
    Inventors: Garth Jason Simpson, James Ulcickas, Fengyuan Deng, Changqin Ding
  • Publication number: 20210177020
    Abstract: The present application relates generally to a process of manufacturing a plurality of products from chia seeds. The process comprises socking chia seeds in a large volume of water for a period of time followed by sonication at an elevated temperature to remove the soluble fiber, the mucilage of chia seeds using vacuum filtration. The oil component is extracted from mucilage removed chia seeds and the leftover is hydrolyzed in presence of an enzyme to afford a product of protein hydrolysates and a product of insoluble fiber of chia seeds. Both the process and the products are within the scope of this application.
    Type: Application
    Filed: December 11, 2020
    Publication date: June 17, 2021
    Applicant: Purdue Research Foundation
    Inventors: Andrea M. Liceaga, Jose Eleazar Aguilar-Toala, Uriel Urbizo-Reyes
  • Publication number: 20210180835
    Abstract: The present disclosure relates to a novel method for operating and controlling a vapor-compression cycle. The method of the present disclosure provides that a turbine-based expander in a heat pump model can achieve greater COP benefit in cooling than heating. Further, phase separation and an evaporator bypass are implemented within the turbine-based expander. Phase separation leads to successful energy recovery and compressor superheat control.
    Type: Application
    Filed: December 4, 2020
    Publication date: June 17, 2021
    Applicant: Purdue Research Foundation
    Inventors: Riley B Barta, Eckhard Achim Groll, Davide Ziviani, Florian Simon
  • Publication number: 20210180070
    Abstract: This present patent application relates to a method for controlling a targeted gene expression with an environmental trigger useful for manufacturing a natural product or an analogue thereof biologically. In particular, the present invention discloses an expression system comprises a gene expressing for a fusion protein of elastin-like polypeptides (ELPs) and a transcription factor, wherein a targeted gene expression is regulated by the phase change of the fusion protein initiated by an environmental trigger, including changes of temperature, pH value, ionic strength or a combination thereof. The method, the expression system and their products are within the scope of this invention.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 17, 2021
    Applicant: Purdue Research Foundation
    Inventors: Kevin V. Solomon, Ethan Hillman, Kok Zhi Lee, Yu Hong Wang
  • Patent number: 11037777
    Abstract: The invention generally relates to systems and methods for separating ions at about or above atmospheric pressure. In certain embodiments, the invention provides systems that include an ionization source that generates ions and an ion trap. The ion trap is maintained at about or above atmospheric pressure and includes a plurality of electrodes and at least one inlet configured to receive a gas flow and at least one outlet. The system is configured such that a combination of a gas flow and one or more electric fields produced by the electrodes separates the ions based on mass-to-charge ratio and sends the separated ions through the at least one outlet of the ion trap.
    Type: Grant
    Filed: June 22, 2020
    Date of Patent: June 15, 2021
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Dalton Snyder, Amar S. Basu, Wen-Ping Peng
  • Patent number: 11037772
    Abstract: The invention generally relates to methods for analyzing a tissue sample. In certain aspects, the invention provides methods that involve obtaining a tissue sample including an unsaturated compound, conducting a radical reaction on the tissue sample that targets a carbon-carbon double bond within the unsaturated compound to thereby produce a plurality of compound isomers, subjecting the plurality of compound isomers to mass spectrometry analysis to identify a location of the carbon-carbon double bond within the unsaturated compound, and quantifying the plurality of compound isomers in order to distinguish normal tissue from diseased tissue.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: June 15, 2021
    Assignee: Purdue Research Foundation
    Inventors: Zheng Ouyang, Yu Xia, Xiaoxiao Ma
  • Patent number: 11031268
    Abstract: This invention generally relates to a device for preparing and transferring a monolayer or thin film. In particular this present invention is a device for preparing and transferring a monolayer or thin film to a substrate using an improved version of the Langmuir-Schaefer technique, which incorporates in situ thermal control, for instance to heat the supporting substrate before and/or during the transfer process.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: June 8, 2021
    Assignee: Purdue Research Foundation
    Inventors: Shelley A. Claridge, Tyler Hayes, David McMillan
  • Patent number: D923059
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: June 22, 2021
    Assignee: Purdue Research Foundation
    Inventors: Lukas Benjamin Inhestern, James Braun, Guillermo Paniagua Perez