Abstract: Padding materials capable of use as or incorporation into protective products, and methods of producing such padding materials. The padding material includes a base and an array of raised unit cells that individually protrude from a surface of the base so that the unit cells are spaced apart from each other. The base and the unit cells are formed of a cured polymeric material that contains fine porosity, and a substrate formed of a textile or fabric material is embedded in the base and permeated by the cured polymeric material.
Type:
Grant
Filed:
April 30, 2021
Date of Patent:
July 23, 2024
Assignee:
Purdue Research Foundation
Inventors:
Michael J. Dziekan, Eric A. Nauman, Kevin G. McIver, Nicolas Leiva-Molano, Jacob McGough, Sean Bucherl
Abstract: Nanoconstructs and compositions comprising a nanoparticle coated with an immunoadjuvant (e.g. ATP) and comprising one or more therapeutic agents (e.g. ICD inducer) encapsulated therein; and methods for treating cancer in a subject using such nanoconstructs and compositions, as well as combination immunotherapies.
Abstract: A splint single-stranded DNA (ssDNA), which comprises a linear splint sequence and a hairpin sequence on each side of the linear splint sequence; a splint ssDNA-ligating linear ssDNA monomeric complex; a method of producing a ssDNA circle; and a kit comprising the splint ssDNA and instructions for using the splint ssDNA to produce a ssDNA circle.
Type:
Application
Filed:
January 12, 2024
Publication date:
July 18, 2024
Applicant:
Purdue Research Foundation
Inventors:
Chengde Mao, Victoria Elizabeth Paluzzi, Cuizheng Zhang
Abstract: A method for inducing a covert misclassification performed on a non-transitory computer readable medium, the method includes identifying a target position. The method further includes creating a spectral perturbation tensor. The spectral perturbation tensor is configured to shift a projection of an initial spectrum towards the target position. Additionally, the method includes combining the spectral perturbation tensor to the initial spectrum. Further, the method includes classifying the combination of the spectral perturbation tensor and the initial spectrum with an established classifier, thereby designing the spectral perturbation tensor such that the combination is misclassified.
Type:
Grant
Filed:
September 10, 2019
Date of Patent:
July 16, 2024
Assignee:
Purdue Research Foundation
Inventors:
Garth Jason Simpson, James Ulcickas, Casey Smith, Alex Sherman
Abstract: Systems and methods for detecting cracks in a surface by analyzing a video, including an full-HD video, of the surface. The video contains successive frames, wherein individual frames of overlapping consecutive pairs of the successive frames have overlapping areas and a crack that appears in a first individual frame of a consecutive pair of the successive frames also appears in at least a second individual frame of the consecutive pair. A fully convolutional network (FCN) architecture implemented on a processing device is then used to analyze at least some of the individual frames of the video to generate crack score maps for the individual frames, and a parametric data fusion scheme implemented on a processing device is used to fuse crack scores of the crack score maps of the individual frames to identify cracks in the individual frames.
Abstract: Apparatus and methods for the measurement and transmission of data pertaining to the tissue of an animal. In one embodiment, there is an implantable device that is wirelessly powered and also wirelessly transmits data. Preferably, the implant measures neuromuscular activity.
Type:
Application
Filed:
August 25, 2023
Publication date:
July 11, 2024
Applicant:
Purdue Research Foundation
Inventors:
Hansraj Singh Bhamra, Jimin Maeng, Rebecca Bercich, Chuizhou Meng, Oren Gall, Young-Joon Kim, Jithin Joseph, William Chappell, Pedro Irazoqui
Abstract: A system and methods for heating and cooling are provided. The system may include an energy collector and an adaptive panel connected to the energy collector. The adaptive panel may a radiative cooling layer configured to dissipate heat from the energy collector. The radiative cooling layer may further include a thermo-responsive polymer configured to adjust transparency depending on temperature. The system may include a solar heating layer configured to absorb solar irradiation that passes through the radiative cooling layer and transfer heat to the energy collector.
Abstract: The present disclosure relates to a novel method for lateral flow immunoassay (LFIA) by utilizing plasmonic enhancement strategy. More specifically, the present disclosure provides a plasmonic enhanced lateral flow sensor (pLFS) concept by introducing a liposome-based amplification of the colorimetric signals on the lateral flow platform for ultrasensitive detection of pathogens.
Abstract: The present disclosure relates to a novel device for selective collection and condensation of an exhaled breath, and the method of using the novel device. The novel device is portable and capable of collecting and condensing reproducible volumes of exhaled breath under about 10 minutes by using a unique temperature-based algorithm.
Type:
Grant
Filed:
June 18, 2019
Date of Patent:
July 9, 2024
Assignee:
Purdue Research Foundation
Inventors:
Jacqueline C. Linnes, Divya Tankasala, Shubhankar S. Takle, Orlando S. Hoilett, Gabriel P. Ng, Michael S. Smith
Abstract: A method of temperature self-calibrating ion-selective electrodes (ISEs) is disclosed which includes calibrating at least two ISEs against a reference electrode (RE) in a calibration solution with a predetermined concentration as the temperature of the calibration solution varies according to a known schedule, wherein the calibration of the at least two ISEs includes determining calibration parameters of each of the at least two ISEs with respect to the RE, placing the at least two calibrated ISEs and the RE into a field solution for determining one or more field parameters of the field solution, measuring voltage across a first of the at least two calibrated ISEs and the RE (Vi), measuring voltage across a second of the at least two calibrated ISEs and the RE (Vi+1), determining Vi?Vi+1, and determining the one or more field parameters.
Abstract: The invention generally relates to systems and methods for performing multiple precursor, neutral loss and product ion scans in a single ion trap. In certain aspects, the invention provides systems including a mass spectrometer having a single ion trap, and a central processing unit (CPU), and storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to apply at least one of the following ion scans to a single ion population in the single ion trap: multiple precursor ion scans, a plurality of segmented neutral loss scans, or multiple simultaneous neutral loss scans.
Abstract: An improved stimulus coil for use in wireless stimulation of biological tissue (e.g., nerves, muscle tissue, etc.) and, in one exemplary implementation, to glaucoma therapy based on the wireless administration of energy to the eye of a mammalian subject (e.g., human, rodent, etc.) to reduce an elevated intraocular pressure (IOP) involving the use of an improved stimulus coil. The improved stimulus coil may be implanted in the eye of a mammalian subject or positioned on the exterior of the eye, such as (by way of example) by being disposed within a contact lens worn by a mammalian subject.
Type:
Grant
Filed:
December 6, 2021
Date of Patent:
July 2, 2024
Assignee:
Purdue Research Foundation
Inventors:
Pedro P. Irazoqui, Gabriel Simon, Gabriel O. Albors, Jack Williams, Quan Yuan
Abstract: A method for spatial analysis of leaf images is disclosed which includes acquiring one or more leaf images of plants, generating 3-dimensional (3D) images from the acquired one or more images from spectral heatmaps, identifying a stem and a plurality of veins, identifying i) one or more of valleys and ridges as regions between two consecutive veins from the plurality of veins, or ii) one or more of peaks and valleys as regions between two consecutive veins from the plurality of veins in the one or more generated 3D images, calculating average slopes in the generated 3D images between i) one or more of peak-to-valley, or ii) ridge-to-valley for the veins, calculating a nitrogen index based on the calculated average slopes, if the calculated average slope is between two thresholds, communicate to a user to add a predetermined chemical to the plants.
Abstract: A method of manufacturing a copper oxide (CuxO) structure onto a Copper (Cu) surface by fabricating an electroactive hierarchical CuxO structure directly onto the Cu surface by laser-induced oxidation (LIO). The generated heat from the laser source provides energy for the oxidation of the Cu surface in the presence of atmospheric oxygen. The electroactive hierarchical CuxO structure is a binder-free nanotextured structure. The electroactive hierarchical CuxO structure may be used as a glucose sensor.
Abstract: A combination chair/bed furniture and method of using. The furniture includes a support frame system and a multi-fold cushion assembly adapted to be supported by a frame of the support frame system. The cushion assembly includes folded cushions that define a seat cushion supported by the frame in a chair configuration of the furniture and when extended defines a mattress supported by the frame and at least one mattress support frame of the support frame system in a bed configuration of the furniture. A seat back is supported by the frame in the chair configuration of the furniture and serves as a headboard or additional mattress in the bed configuration.
Abstract: Disclosed herein is a platform and method to quantify spatiotemporal tissue swelling during biologics injection, and to predict associated increase in the mechanical stress and interstitial fluid pressure (IFP) of tissues. Accurate measure and estimation of tissue swelling, thus, can be quantitative and predictive indicator of the IPD.
Abstract: A method for hand pose identification in an automated system includes providing map data of a hand of a user to a first neural network trained to classify features corresponding to a joint angle of a wrist in the hand to generate a first plurality of activation features and performing a first search in a predetermined plurality of activation features stored in a database in the memory to identify a first plurality of hand pose parameters for the wrist associated with predetermined activation features in the database that are nearest neighbors to the first plurality of activation features. The method further includes generating a hand pose model corresponding to the hand of the user based on the first plurality of hand pose parameters and performing an operation in the automated system in response to input from the user based on the hand pose model.
Abstract: A wearable device worn by a user is disclosed which includes a plurality of input device interfaces each configured to receive input from a sensor coupled to a user, a controller configured to generate a two-dimensional map of the user's three-dimensional space based on the received inputs, and a plurality of haptic feedback devices disposed on the wearable device, wherein the controller is configured to selectively activate each of the plurality of haptic feedback devices to signal the user's position in the three-dimensional space based on the generated two-dimensional map as the user moves in the three-dimensional space.
Type:
Application
Filed:
December 6, 2023
Publication date:
June 13, 2024
Applicant:
Purdue Research Foundation
Inventors:
Ethan M. Brown, Eric P. O'Keefe, Fernando Vega, Shyam K. Reddy, Ivan Malov
Abstract: A three-dimensional nanolithography system includes forming a photocurable resin including one or more organic monomers, a photoinitiator, and an inhibitor, defining a lithographical patterning region, directing a light beam toward the lithographical patterning region to initiate polymerization, and controlling an initiator depletion technique to reduce an undesired portion of the polymerization.
Type:
Application
Filed:
December 13, 2023
Publication date:
June 13, 2024
Applicant:
Purdue Research Foundation
Inventors:
Liang Pan, Xianfan Xu, Bryan William Boudouris
Abstract: The present disclosure relates to a novel continuous laser nanoforming device, and the methods to make and use the continuous laser nanoforming device.
Type:
Grant
Filed:
March 5, 2020
Date of Patent:
June 11, 2024
Assignee:
Purdue Research Foundation
Inventors:
Ramses Valentin Martinez, Debkalpa Goswami