Abstract: Variable thermal resistors, systems, and methods suitable for modulating heat transport between a heat source and a heat sink based on a degree of compression of a reversibly-compressible, open-pore graphene foam within the variable thermal resistors. The variable thermal resistor is configured to controllably vary heat transport therethrough by controlling the degree of compression of the graphene foam.

Abstract: A runway incursion avoidance system includes a plurality of surveillance sub-systems that are configured to detect whether an approach and a surface of an aviation runway is currently occupied or will soon be occupied by an object, such as an aircraft, vehicle, pedestrian, wild animal, or other foreign object. The surveillance sub-systems each broadcast one or more occupancy states of the aviation runway. The runway incursion avoidance system further includes a plurality of runway status light sub-systems that control one or more runway status lights depending on the occupancy states broadcast by the surveillance sub-systems. The runway status lights may include Departure and Approach Warning Lights (DALs) to indicate runway status to aircraft taking off from the runway and landing on the runway, or Runway Entrance Lights (RELs) to indicate runway status to aircraft, vehicles, and pedestrians preparing to cross a runway.

Abstract: A field-effect transistor (FET) includes a fin, an insulator region, and at least one gate. The fin has a doped first region, a doped second region, and an interior region between the first region and the second region. The interior region is undoped or more lightly doped than the first and second regions. The interior region of the fin is formed as a superlattice of layers of first and second materials alternating vertically. The insulator layer extends around the interior region. The gate is formed on at least a portion of the insulator region. The insulator layer and the gate are configured to generate an inhomogeneous electrostatic potential within the interior region, the inhomogeneous electrostatic potential cooperating with physical properties of the superlattice to cause scattering of charge carriers sufficient to change a quantum property of such charge carriers to change the ability of the charge carriers to move between the first and second materials.

Abstract: The invention generally relates to high-throughput label-free enzymatic bioassays using desorption electrospray ionization-mass spectrometry (DESI-MS).

Abstract: A mixing assembly includes a mixing basin, first and second pluralities of mixing paddles, and at least one motor. The mixing basin includes first and second parallel shafts extending therethrough. Each of the first and second pluralities of mixing paddles are positioned in an interior of the mixing basin. Each paddle of the first plurality of mixing paddles is coupled with the first shaft and configured to rotate about a first axis and each paddle of the second plurality of mixing paddles is coupled with the second shaft and configured to counter-rotate about a second axis. The counter-rotating mixing paddles are spaced apart to define a shear gap therebetween, and the motor is operable to drive the counter-rotation of the mixing paddles.

Abstract: An ultrafast system for detecting incidence of a single photon is disclosed which includes a single photon avalanche detector having an inherent bandgap, a source of probe light configured to apply an incident beam onto the single photon avalanche detector, wherein the probe light is configured to apply energy less than the bandgap, and a probe beam detector, configured to receive a reflected probe beam from the single photon avalanche detector, wherein the probe beam detector is adapted to generate a signal signifying: i) incidence of a single photon from a control beam onto the single photon avalanche detector.

Abstract: A method of determining the contributions of multiple incident photons to an output of a sensor, including providing a photonic sensor having a sensor input and capable of generating an electrical signal proportional to a number of photons interacting with the photonic sensor input as a function of time, calibrating the photonic sensor such that a response of the photonic sensor to a single photon detected is in a waveform having an amplitude and a time, wherein the product of the amplitude and the time is statistically bounded, determining a probabilistic boundary between one or more of electrical, optical, and thermal sources of noise of the sensor, acquiring a response wave form from the photonic sensor through analog-to-digital conversion with a resolution in amplitude and time corresponding to accuracy required in quantifying the response wave form, storing each acquired response wave form, individually, in a format selected from the group consisting of real-time and buffered packets in digital form, and

Abstract: The invention generally relates to systems and methods for sample analysis using swabs. In certain aspects, the invention provides systems that include a probe having a conductive proximal portion coupled to a porous material at a distal portion of the probe that is configured to retain a portion of a sample that has contacted the porous material, and a mass spectrometer having an inlet. The system is configured such that the porous material at a distal portion of the probe is aligned over the inlet of the mass spectrometer.

Abstract: An example device is described for facilitating polygon localization. In various aspects, the device can comprise a processor. In various instances, the device can comprise a non-transitory machine-readable memory that can store machine-readable instructions. In various cases, the processor can execute the machine-readable instructions, which can cause the processor to localize a polygon depicted in an image, based on execution of a deep learning pipeline. In various aspects, the deep learning pipeline can comprise a circular-softmax block.

Abstract: The invention generally relates to systems and methods for conducting reactions and screening for reaction products.

Abstract: The described compounds are of the class of cyclic nucleotides, both mono- and di-nucleotides, which play diverse roles in the prokaryotes and eukaryotes having the general formula which inhibit phosphodiesterases that inhibit cyclic mononucleotide or dinucleotides and/or both mononucleotide and dinucleotide. These compounds have potential diverse applications as antiviral, antibacterial, anti-inflammatory and anticancer agents, including cancer immunotherapy. Pharmaceutical compositions and methods for treating those kinase related diseases are within the scope of this invention.

Abstract: An atmospheric water harvesting system may include a cellulose composite material. The composite material may include a cellulose scaffold comprising cellulose fiber bundles. Each of the bundles may include a plurality of fibers. Hygroscopic salt ions may be intercalated in the cellulose scaffold and bound to the cellulose fibers. Water may be extracted from the composite material.

Abstract: A method of optimizing an Urban air mobility (UAM) network is disclosed which includes receiving a predetermined vertiport network, wherein each vertiport in the predetermined network is represented by a plurality of parameters, receiving a customer demand schedule representing customer demand for each said vertiport, using a model simulating the UAM network thus outputting a solution for the plurality of parameters, inputting the output of the simulation to a genetic algorithm (GA), optimizing the GA to thereby generate an optimized solution based on minimizing a mathematical function associated with the plurality of parameters until a predetermined termination criteria associated with network size is reached, and outputting the optimized solution.

Abstract: The invention related to single photon emission systems based on nano-diamonds. Single-photon sources have a broad range of applications in quantum communication, quantum computing and quantum metrology.

Abstract: The present invention relates to a low-cost, thermally reversible valve for paper-fluidic diagnostic devices. In particular, this invention demonstrates a tunable valve mechanism fabricated by wax-ink printing and localized heating via thin-film resistors to sequentially release liquids through a cellulose or nitrocellulose membrane. The wax-ink valve can obstruct fluid flow for a sustained time and are thermally actuated to release a controlled amount of liquid past the valve. This integrated paper-fluidic diagnostic assay device requires minimal user involvement, can be easily manufactured and tuned to meet various fluid delivery timing and incubation needs.

Abstract: An in-memory vector addition method for a dynamic random access memory (DRAM) is disclosed which includes consecutively transposing two numbers across a plurality of rows of the DRAM, each number transposed across a fixed number of rows associated with a corresponding number of bits, assigning a scratch-pad including two consecutive bits for each bit of each number being added, two consecutive bits for carry-in (Cin), and two consecutive bits for carry-out-bar (Cout), assigning a plurality of bits in a transposed orientation to hold results as a sum of the two numbers, for each bit position of the two numbers: computing the associated sum of the bit position; and placing the computed sum in the associated bit of the sum.

Abstract: A laser beam steering system is disclosed which includes a laser source which produces a pulsed laser light beam with a frequency comb spectrum, a first metasurface configured to i) directly receive the pulsed laser and ii) directly generate a diffracted pulsed laser output at different frequencies with a beam at a center frequency normal to the first metasurface; and a second metasurface configured to i) directly receive the diffracted pulsed laser output and ii) to focus onto different foci at a focal plane, light propagating from the focal plane leads to generation of one or more optical beams that are controlled in space and time.

Abstract: A batteryless, chipless, sensor is disclosed which includes a substrate, at least two conductive strips disposed on the substrate, a passivation layer encasing the substrate and the at least two conductive strips, wherein the conductive strips are adapted to respond to an interrogation signal from a reader having a first polarization, with a response signal at a second polarization different than the first polarization.

Abstract: Skin-mountable electronic devices and methods suitable for fabricating and using the devices. One embodiment of such a device includes a flexible structure comprising a pattern of individual interconnected traces each comprising a portion of an electrically-conductive layer that overlies and directly contacts an underlying portion of an elastomeric layer. At least some of the portions of the electrically-conductive layer within the pattern are functional electrodes of the skin-mountable electronic device.

Abstract: Systems and methods for wideband RF interference detection and suppression include an open-circuit stub, a first voltage peak detector, a second voltage peak detector, an analog-to-digital converter (ADC), and a controller. The open-circuit stub is configured to receive an input signal. The first voltage peak detector is coupled at the open end of the open-circuit stub and configured to output a first voltage signal based on a portion of the input signal. The second voltage peak detector is coupled a distance away from the open end of the open-circuit stub and configured to output a second voltage signal based on the portion of the input signal. The controller is configured to generate an output control signal operable to adjust a signal filter based on the first digital voltage signal and the second digital voltage signal to suppress the portion of the input signal.