Abstract: A method of in situ point spread function (PSF) retrieval is disclosed which includes encoding 3D location of molecules into PSFs, receiving molecule-generated images containing PSFs, segmenting the images into sub-PSF, initializing template PSFs from a pupil function, determining a statistical measure of a predetermined function between the sub- and template PSFs, associating each of the sub-PSFs with a template PSF, aligning and averaging the sub-PSF, applying a phase retrieval algorithm to the averaged sub-PSFs to update the pupil function, regenerating the template PSFs, repeating until a difference between a new and a prior generation pupil function is below a predetermined threshold, generating in situ PSFs from the last pupil function, and applying a maximum likelihood estimation algorithm based on the in situ PSFs and the sub-PSF to thereby generate lateral and axial locations of molecules.

Abstract: An auto-injector includes a housing and an actuation assembly. The housing includes a central cavity, opposing ends, and a longitudinal axis defined spanning between the opposing ends. The actuation assembly is shaped to position within the central cavity. The actuation assembly is configured to at least partially internally house a spring, a spring compression member, a needle operable to eject a fluid therefrom, a firing member selectively translatable between an unfired position and a fired position, and a firing initiation member. While in the unfired position, the needle is held within the central cavity of the housing. While in the fired position, the needle is extended outward from the central cavity of the housing.

Abstract: A method of generating an image or video of a field of interest of a sample which includes obtaining i) a first RGB image from a field of interest of a sample, and ii) hyperspectral data from a subarea of the field of interest, extracting an RGB image of the subarea from the first RGB image of the field of interest, applying the hyperspectral data of the subarea to conduct a spectroscopic analysis of a sample thereby generating spectral parameters, inputting i) the spectral parameters, and ii) the first RGB image, collectively as training input data to a deep learning model (DLM), training the DLM with the training input data thus generating a trained DLM, obtaining and inputting a second RGB image of about the field of interest to the trained DLM, and outputting from the trained DLM a spectral map for the field of interest.

Abstract: Some examples provides a set of frameworks, process and methods aimed at enabling the expression and exploration of free-form and parametric 3D shape designs enabled through natural interactions with a hand-held mobile device acting as a controller for 3D virtual objects. A reference plane in a virtual space generated by the location of the mobile device may be used to select a 3D virtual object intersected by the reference plane. Positioning of the mobile device may also be used to control a pointer in the virtual space. In an example, the orientation of the mobile device may be detected by an accelerometer or gyroscope. In example, the position of the mobile device may be detected by a position sensor.

Abstract: This invention relates to an improved version of paper-based analytical device and method for chromatographic chemical or immunoassays. Particularly, this present invention discloses a device and a method for reducing smears and improving sharpness and intensity of test sample readout for a multi-step chemical assay or immunoassay by introducing two additional elements, a time-delay pad (2) and a mixer (1), to the conventional two-dimensional paper network device (2DPN).

Abstract: A method is provided for determining the surface viscosity of a liquid in which a thread is formed from a drop of the liquid. The thread is lengthened and its minimum radius h0 is determined at multiple times between the thread formation and thread pinch-off. The minimum radius and associated time values are used to determine a linear relationship of minimum radius and time, with the coefficient of the linear relationship, or the slope X of the line in the linear relationship, corresponding to the surface viscosity ?s of the liquid according to one of the following equations: x = 0 . 0 ? 7 ? 0 ? 9 1 + 5 ? B s0 / 3 ? h 0 , ( 1 ) where Bs0=?s/?R in which h0 is defined as above, R is the dimension of the feature on which the drop is provided and ? is the bulk viscosity of the liquid, or x = 0 .

Abstract: A printed radiation sensor that includes a substrate, an interdigitated electrode, and a conductive polymeric film. The interdigitated electrode including a first electrode with a plurality of first electrode digits and a second electrode with a plurality of second electrode digits. The interdigitated electrode disposed on the substrate. The conductive polymeric film including a blend of poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) and polyvinyl alcohol (PVA). The PEDOT:PSS is configured to provide an electrically conductive medium. The PVA is configured to provide ductility and stability of the printed radiation sensor. Upon radiation exposure, the PVA is further configured to crosslink within a material matrix of the printed radiation sensor militating against the recombination of chain scission by forming a semi-interpenetrating polymer network (SIPN) with the PEDOT:PSS to provide an enhanced and stable impedance reading.

Abstract: A tunable radio frequency (RF) resonator may include an RF cavity core defining an RF cavity. The RF cavity core may include a post positioned within the RF cavity. The tunable RF resonator may further include a flexible membrane covering the RF cavity. A gap may be defined between the flexible membrane and the post. An actuator may cause movement of the flexible membrane and vary the distance between the membrane and the post. The RF cavity core is may be injection molded plastic with a metalized electroplating.

Abstract: A cable management apparatus includes a housing, an axle, a rotary member, and a gear member. The housing includes a front face and a rear face, the front face including a first opening. The axle is positioned within the housing and defines a longitudinal axis. The rotary member is positioned within the first opening and defines a bore shaped to receive a cable therethrough. The gear member provides a rotatable coupling between the rotary member, the housing, and the axle. The gear member further includes a first bearing and a second bearing. The first bearing provides a rotatable coupling between the rotary member and the axle, and the second bearing provides a rotatable coupling between the rotary member and the housing.

Abstract: A method of generating an output movement layout for a traffic intersection, includes receiving intersection geographical data, establishing a center point for the intersection, receiving connected vehicle (CV) data from vehicles approaching and within the traffic intersection based on a predetermined distance from the center point, establishing an area of interest for the intersection based on the received CV data, establishing entry and exit headings for each vehicle based on the CV data, generating directional groups based on the entry and exit headings of each vehicle, and generating an output movement layout for the intersection based on the generated directional groups.

Abstract: The invention generally relates to charged mass label compositions and methods of use thereof for detecting a target analyte in a sample. In certain aspects, the invention provides a charged mass label composition including an affinity reagent, and a mass label precursor bound to the affinity reagent. The mass label precursor includes a label binding unit and a mass label. The label binding unit reversibly binds the mass label to the affinity reagent. The mass label includes a charge unit and a mass label unit having a pre-defined mass-to-charge-value in a mass spectrum.

Abstract: The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for incorporating the compounds as used for the targeted imaging of tumors. Conjugation of the amino acid linking groups increase specificity and detection of the compound. Methods and compositions for use thereof in diagnostic imaging are contemplated.

Abstract: A method of producing a sulfonated polymer. The method includes providing a source for a quantity of a polymer containing polymer fibers. The quantity of the polymer is heated while immersed in sulfuric acid to 100-200° C. for a period time in a closed reactor containing an atmosphere and capable of holding pressure generated by a reaction between the quantity of the polymer and the sulfuric acid resulting in a sulfonated polymer, wherein substantially all the quantity of the polymer from the source is converted into sulfonated polymer. The sulfonated polymer is then removed from the reactor and dried. An electrode suitable for use as an electrode in an electrochemical energy storage cell is disclosed. The electrode contains amorphous porous carbon fibers made from a sulfonated polymer with a morphology wherein the amorphous porous carbon fibers have the morphology of the sulfonated polymer from which they are made.

Abstract: High-resolution, selective, and self-optimizing haptic and electrotactile display and methods of use. In an embodiment of a feedback system referenced herein, the feedback system includes a prosthesis configured to be worn by an individual, including at least one prosthesis sensor configured to detect a state or condition in an environment of the at least one prosthesis sensor, and at least one actuator in communication with the at least one prosthesis sensor and configured to receive data relating to the detected state or condition and to stimulate a nerve of the individual; a neural sensor positioned upon or within the individual, configured to detect a neural response relating to the stimulation of the nerve by the at least one actuator; and a processor in communication with at least one of the at least one prosthesis sensor, at least one of the at least one actuator, and the neural sensor.

Abstract: Processes for producing sheet metal products by machining a solid metal body with a cutting tool in a single step to continuously produce a continuous bulk form from material obtained from the solid metal body, and without performing a hot rolling operation thereon, cold rolling the continuous bulk form to produce a sheet metal product. The machining step is a large-strain machining process capable of being directly performed on an as-cast ingot or other solid body to produce a continuous intermediate product that can be directly cold rolled without any intervening hot rolling operation, and optionally without homogenization or annealing.

Abstract: The disclosure develops a multi-scale model that partitions the device into different spatial regions where the high carrier domains are treated as reservoirs in local equilibrium and serve as injectors and receptors of carriers into the neighboring reservoirs through tunneling and thermionic emission. The nonequilibrium Green's function (NEGF) formalism is used to compute the dynamics (states) and the kinetics (filling of states) in the entire extended complex device. The local density of states in the whole device is computed quantum mechanically within a multi-band tight binding Hamiltonian. The model results agree with experimental I-V curves quantitatively.

Abstract: A method of supervising a complex system includes acquiring and storing failures data and repair resources information regarding the complex system, identifying failure networks and structures of the complex system. Failure types associated with the failure networks of the complex system are determined. The method includes generating a plurality of failure prevention and repair (FPR) sequences, wherein each FPR is associated with the failure networks and the failure types. The generated FPR sequences are analyzed to select a set of FPR sequences and associated repair resources. The method further comprises applying the selected one of the plurality of failure prevention and repair sequences to the complex system, thereby managing the complex system.

Abstract: A method for spontaneous emulsification comprising mixing (i) an aqueous phase comprising a partitioning agent which contains a partitioning anion which determines the hydrophilicity of the partitioning agent, alone or in further combination with an electrolyte, with (ii) an oil phase comprising a phase-transfer agent, wherein the phase-transfer agent creates and promotes an interfacial flux of an anion and promotes the formation of droplets at a liquid-liquid interface of the aqueous phase and oil phase; and a method for spontaneous electro-emulsification comprising generating an ionic flux across the liquid-liquid interface by applying an electrical potential.

Abstract: A method and apparatus for generating solar power in agricultural fields while minimally impacting crop growth and farming efforts, including positioning an elongated solar panel above crops, wherein the elongated solar panel runs generally parallel to longitudinal lines and wherein the elongated solar panel has at least one solar transducing face and an endless edge surrounding and perpendicular to the at least one solar transducing face, automatically pivoting the elongated solar panel such that the at least one solar transducing face is oriented parallel to incident solar rays during predetermined times when plant growth requires incident sunlight, automatically pivoting the elongated solar panel such that the at least one solar transducing face is oriented parallel to the vertical during rain, automatically pivoting the elongated solar panel out of the way of heavy farm equipment, and automatically pivoting the elongated solar panel such that the at least one solar transducing face is oriented perpendicul

Abstract: A metal-ion deposition regulator to regulate the flux and deposition of metal ions in an electrochemical cell. The regulator containing two membranes made of a polymer and a plurality of two-dimensional porous nanosheets sandwiched between the two membranes. The regulator is capable of distributing flux of metal ions passing through the metal-ion deposition regulator and regulating the deposition of the metal ions onto the cathode or anode thereby suppressing dendrite growth in the electrochemical cell. An electrochemical cell containing an anode, a cathode, a liquid electrolyte, and a metal-ion deposition regulator. A method of making a metal-ion deposition regulator. The method includes fabricating two-dimensional porous nanosheets utilizing graphene oxide as an expendable template, and sandwiching the porous nanosheets between two membranes made of a polymer such that the nanosheets are in contact with the two membranes.