Patents Assigned to Purdue Research
  • Drainage devices having self-clearing and flow resistance control capabilities, and microactuators for use therewith
    Patent number: 11918513
    Abstract: Drainage devices have a self-clearing capability for reducing obstructions and a controllable flow restriction capability for controlling drainage flow, and microactuators for providing such capabilities. Such a microactuator includes a frame and an appendage anchored to the frame such that the frame supports the appendage, the frame at least partially surrounds the appendage, and the appendage is disposed in an opening or window defined by the frame. The appendage includes a platform and at least one beam that anchors the platform to the frame to enable the appendage to deflect out of a plane defined by the frame. The platform may include a ferromagnetic material that enables the appendage to deflect in response to an applied magnetic field.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: March 5, 2024
    Assignee: Purdue Research Foundation
    Inventors: Hyowon Lee, Simon John, Hyunsu Park
  • Light activated photoreaction via genetic hybridization of far-red fluorescent protein and silk
    Patent number: 11925118
    Abstract: A method of inactivating harmful microorganisms of a filtration medium including pathogenic bacteria and viruses is disclosed which includes placing a predetermined quantity of a hybridized fluorescent silk on to a filtration medium, applying light for a predetermined amount of time to the placed quantity of the hybridized fluorescent silk, and passing a fluid through the medium, wherein the fluid is one of substantially air or substantially water, wherein the hybridized fluorescent silk is one of KillerRed, SuperNova, KillerOrange, Dronpa, TurboGFP, mCherry, or any combination thereof.
    Type: Grant
    Filed: March 25, 2022
    Date of Patent: March 5, 2024
    Assignee: Purdue Research Foundation
    Inventors: Jung Woo Leem, Seung Ho Choi, Young L. Kim
  • Light activated photoreaction via genetic hybridization of far-red fluorescent protein and silk
    Patent number: 11925117
    Abstract: A method of disinfection of a surface of a subject of harmful microorganisms including pathogenic bacteria and viruses upon visible light irradiation using a hybridized fluorescent silk is provided. The method includes placing a predetermined quantity of the hybridized fluorescent silk i) directly on to a skin surface of a subject; or ii) on a medium and then placing the medium on the skin surface of the subject. The method further includes applying light in the visible spectrum for a predetermined amount of time to the placed quantity of hybridized fluorescent silk, wherein the hybridized fluorescent silk is one of KillerRed, SuperNova, KillerOrange, Dronpa, TurboGFP, mCherry, or any combination thereof.
    Type: Grant
    Filed: March 25, 2022
    Date of Patent: March 5, 2024
    Assignee: Purdue Research Foundation
    Inventors: Jung Woo Leem, Seung Ho Choi, Young L. Kim
  • Thermally-modulated ultrasound contrast agents
    Patent number: 11918661
    Abstract: The present disclosure relates to a novel nano-droplet composition comprising a fluorocarbon core and a polymeric shell, and the method of using and making the novel nano-droplet composition. The fluorocarbon core and the polymeric shell of the novel nano-droplet form a micelle with a size range of 10-1000 nm. The fluorocarbon core comprises at least one fluorocarbon compound with a formula of CnF2n+2 and n is 5-10. The fluorocarbon compound is substantial in liquid form. And the nano-droplet composition has a temperature profile such that the nano-droplet composition has a temperature range of 20-60° C. throughout a temperature modulation process, and has a temperature of about 37° C. prior to administration to a human, animal, biological cell, or tissue subject.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: March 5, 2024
    Assignee: Purdue Research Foundation
    Inventors: Pavlos P Vlachos, Anastasiia Vasiukhina, Luis Solorio
  • System and method for energy usage accounting in software applications
    Patent number: 11922100
    Abstract: A method for generating an energy usage profile for a software program executed in a computing device includes generating a call trace of an executed system call, identifying a first power consumption and duration of a first power state due to the first system call using a model, identifying a second power consumption and duration of a second power state based on the model, and generating an energy usage profile for the software program. The energy usage profile includes energy consumption of the computing device for the system call based on the first power consumption level multiplied by the first duration and the second power consumption level multiplied by the second duration associated an identifier for the call trace.
    Type: Grant
    Filed: August 30, 2022
    Date of Patent: March 5, 2024
    Assignee: Purdue Research Foundation
    Inventors: Yu Charlie Hu, Abhinav Pathak
  • LIGHT PIPE MICROSCOPE FOR LARGE-SCALE DYNAMIC IMAGING
    Publication number: 20240069321
    Abstract: An apparatus for large-scale dynamic imaging of a sample is described. The apparatus includes an optical detector, a light guide, a dichroic beam splitter, and a light source. The light guide includes a first portion and a second portion. The second defines a tapered shape such that a first diameter defined by a distal end of the second portion is smaller than a second diameter defined by a proximal end of the second portion. The dichroic beam splitter is positioned between the first portion and the second portion of the light guide. The light source is configured to direct a light beam through an external surface of the dichroic beam splitter. The dichroic beam splitter is configured to direct the light beam toward the second open end of the light guide and transfer the return emitted signal through the light guide to the optical detector.
    Type: Application
    Filed: August 30, 2023
    Publication date: February 29, 2024
    Applicant: Purdue Research Foundation
    Inventor: Meng Cui
  • DIIODOHYDROXYQUINOLINE FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE INFECTION
    Publication number: 20240066022
    Abstract: The present application generally relates to a method to treat a patient with a bacterial infection caused by Clostridium difficile. Particularly the method compromises the step of administering a therapeutically effective amount of diiodohydroxyquinoline, with or without one or more anti-infective agents, to the patient in need of relief from said infection. Methods of uses and composition matters are within the scope of this disclosure.
    Type: Application
    Filed: November 6, 2023
    Publication date: February 29, 2024
    Applicant: Purdue Research Foundation
    Inventors: Mohamed Seleem, Nader Abutaleb
  • SYNERGISTIC EFFECT OF ISOXABEN AND CELLULOSIN AS AN HERBICIDE
    Publication number: 20240065270
    Abstract: The present application relates to a method of weed control for a crop field using a synergistic effect of two herbicides cellulosin and isoxaben. A composition matter together with said method comprising cellulosin and isoxaben is within the scope of the present invention.
    Type: Application
    Filed: November 6, 2023
    Publication date: February 29, 2024
    Applicant: Purdue Research Foundation
    Inventor: Chunhua Zhang
  • Method of identifying vehicle turning movements at intersections from trajectory data and reallocating green time therefor
    Patent number: 11915585
    Abstract: A method of generating an output movement layout for a traffic intersection is disclosed which includes receiving intersection geographical data, establishing a center point for the intersection, receiving vehicle global positioning system (GPS) data, establishing a radius of interest for the intersection based on the received vehicle GPS data, establishing entry and exit headings for each vehicle based on the GPS data, generating an angular cluster chart based on the entry and exit headings of each vehicle, and generating an output movement layout for the intersection based on the generated angular cluster chart. Further, a method for green time reallocation at traffic signals is disclosed that is based on the congestion experienced by vehicles identified as following specific movements.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: February 27, 2024
    Assignee: Purdue Research Foundation
    Inventors: Enrique Daniel Saldivar Carranza, Haoxiang Howell Li, Darcy Bullock
  • Ion generation using modified wetted porous materials
    Patent number: 11913924
    Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.
    Type: Grant
    Filed: March 30, 2023
    Date of Patent: February 27, 2024
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Zheng Ouyang
  • CO-FORMULATION OF POLYMYXINS FOR INHALATION
    Publication number: 20240058375
    Abstract: The present disclosure generally relates to a method for reducing the toxicity of polymyxins as a therapeutic agent comprising the step of coadministration of an aminoglycoside; a method for improving the aerosolization of an aminoglycoside comprising the step of combination formulation with a polymyxin; and a process for manufacturing a dry powder composition comprising a polymyxin and aminoglycoside. Pharmaceutical compositions and methods of treatment for lung infections are within the scope of this invention.
    Type: Application
    Filed: October 27, 2021
    Publication date: February 22, 2024
    Applicant: Purdue Research Foundation
    Inventors: Qi ZHOU, Maizbha Uddin AHMED, Mohammad Abul Kalam AZAD, Jian LI
  • PROCESS AND COMPOSITION MATTER OF NANOPARTICLE FORMULATION FOR SYSTEMIC TREATMENT OF SEPSIS
    Publication number: 20240058416
    Abstract: The present invention generally relates to a process of nanoparticle formulations and its composition matter for systemic treatment of sepsis. In particular, this invention discloses a method for preparing tannic acid-ferric nanoparticles, optionally incorporating a component of vitamin D3, coated with zwitterionic chitosan (ZWC) and polymyxin B (PMB). The invention described herein also pertains to pharmaceutical compositions and methods for the treatment of sepsis.
    Type: Application
    Filed: November 1, 2023
    Publication date: February 22, 2024
    Applicant: Purdue Research Foundation
    Inventors: Yoon Yeo, Simseok Yuk
  • Unmanned vehicles capable of environmental interaction
    Patent number: 11905005
    Abstract: An unmanned ground-based system is disclosed which includes a chassis, a plurality of wheels coupled to the chassis and configured to allow the chassis to move about a surface, a plurality of propeller assemblies configured to provide on-ground motion propulsions, a boom having a boom propeller assembly with a propeller disposed on a plane generally perpendicular to the plurality of propeller assemblies, configured to independently and selectively provide positive and negative rectilinear thrust vectors, and an end-effector coupled to a distal end of the boom, the end-effector having a force sensor configured to provide contact force between the end-effector and an object, wherein the contact force is used as a feedback signal to determine magnitude of the positive and negative rectilinear thrust vectors that is generated by the propeller of the boom propeller assembly.
    Type: Grant
    Filed: August 16, 2021
    Date of Patent: February 20, 2024
    Assignee: Purdue Research Foundation
    Inventors: David J. Cappelleri, Daniel R. McArthur
  • Enclosed desorption electrospray ionization probes and method of use thereof
    Patent number: 11903707
    Abstract: The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.
    Type: Grant
    Filed: March 11, 2022
    Date of Patent: February 20, 2024
    Assignee: Purdue Research Foundation
    Inventors: Robert Graham Cooks, Zheng Ouyang, Chien-hsun Chen, Ziqing Lin, Livia Schiavinato Eberlin
  • DIRECT REDUCTIVE AMINATIONS WITH MONOTRIFLUOROACETOXY BORANE-AMINES
    Publication number: 20240051974
    Abstract: A direct reductive amination of aldehydes, ketones, and keto acids with trifluoroacetoxyborane-amines (TFAB-amines), which are mild reductive amination agents prepared by monoacetoxylation of borane-amines; Aromatic and aliphatic lactams are obtained via a tandem reductive amination-cycloamidation of keto acids using TFAB-amine.
    Type: Application
    Filed: August 1, 2023
    Publication date: February 15, 2024
    Applicant: Purdue Research Foundation
    Inventor: Padinjaremadhom V. Ramachandran
  • NANODEVICE, METHOD OF MAKING THE SAME, AND METHOD OF USING THE SAME
    Publication number: 20240045002
    Abstract: A nanodevice provides for electric-field control of magnon-QSD interactions. The nanodevice includes a ferroelectric substrate, a ferromagnetic material disposed over the ferroelectric substrate, and a nanodiamond including an ensemble of nitrogen-vacancy (NV) spins, each NV magnetically interfacing with the ferromagnetic material. An electric field is measured by applying a voltage across the ferroelectric substrate and the ferromagnetic material, changing a magnon excitation spectrum of the ferromagnetic material with respect to an electron spin resonance frequency of the ensemble of NV spins, and measuring a relaxation rate of the ensemble of NV spins.
    Type: Application
    Filed: October 13, 2023
    Publication date: February 8, 2024
    Applicant: Purdue Research Foundation
    Inventors: Vladimir M. Shalaev, Pramey Upadhyaya, Abhishek Bharatbhai Solanki, Simeon I. Bogdanov, Yong P. Chen, Mohammad Mushfiqur Rahman, Avinash Rustagi
  • METHOD OF SELECTING A GILT FOR BREEDING
    Publication number: 20240044923
    Abstract: A method of eliminating a gilt from selection for breeding comprising (i) obtaining a vaginal lipidome profile from a gilt at around the time of weaning and (ii) using the vaginal lipidome profile to assign the gilt as probable fertile or infertile; a method of analyzing a lipidome profile of a gilt vaginal swab comprising (i) receiving a vaginal swab obtained from a gilt at around the time of weaning and (ii) analyzing, or having analyzed, lipids obtained from the vaginal swab, and (iii) determining, or having determined, decreases/increases in lipid levels compared to normal; and a kit for obtaining a vaginal swab from a gilt.
    Type: Application
    Filed: December 17, 2021
    Publication date: February 8, 2024
    Applicant: Purdue Research Foundation
    Inventors: Theresa M. Anderson, Christina R. FERREIRA, Kara STEWART, Kayla MILLS
  • POWER DEVICES WITH IMPROVED ON-RESISTANCE
    Publication number: 20240047531
    Abstract: A metal oxide semiconductor (MOS)-based power device includes a semiconductor region, drain and source electrodes, a gate electrode separated from the semiconductor region by SiO2, where the channel length (CHL) has a range of between about 0.6 ?m and about 0.5 ?m, the silicon dioxide has a corresponding thickness (tox) range of between about 5 nm to about 30 nm, where the CHL has a range of between about 0.5 ?m and about 0.4 ?m, the tox has a corresponding range of between about 5 nm to about 25 nm, where the CHL has a range of between about 0.4 ?m and about 0.3 ?m, the tox has a corresponding range of between about 5 nm to about 20 nm, where the CHL has a range of between about 0.3 ?m and about 0.2 ?m, the tox has a corresponding range of between about 5 nm to about 15 nm.
    Type: Application
    Filed: July 30, 2023
    Publication date: February 8, 2024
    Applicant: Purdue Research Foundation
    Inventors: James Albert Cooper, Dallas Todd Morisette
  • A METHOD AND SYSTEM FOR SHARING QUANTUM ENTANGLEMENT BETWEEN DISTANT NODES WITHOUT QUANTUM MEMORIES
    Publication number: 20240048247
    Abstract: A method of entangling photons in a distributed quantum-based communication system is disclosed which includes generating sets of entangled photon pairs between a plurality of remote nodes (Nodes Ai and Nodes Bi) and a central entangling node (Node C), wherein Nodes Ai and Bi are in both quantum communication and classical communication with Node C, wherein one photon of a first entangled photon pair set is transmitted Node Ai and one photon of a second entangled photon pair set is transmitted to Node Bi, each over the associated quantum channels, and performing Bell-state measurements between the other photon of the first entangled photon pair and the other photon of the second entangled photon pair, such that if the photons arrive at about same time having about same frequency, then the photon pairs are marked as being entangled.
    Type: Application
    Filed: July 9, 2023
    Publication date: February 8, 2024
    Applicant: Purdue Research Foundation
    Inventors: Mahdi Hosseini, Andrew M Weiner
  • COMPOUNDS FOR THE TREATMENT OF SARS
    Publication number: 20240043417
    Abstract: Bis-amide inhibitors of SARS-CoV-2 (COVID) and methods of using them to treat a severe acute respiratory syndrome.
    Type: Application
    Filed: November 30, 2021
    Publication date: February 8, 2024
    Applicant: Purdue Research Foundation
    Inventors: Arun K. Ghosh, Hiroaki Mitsuya, Andrew Mesecar