Abstract: The present application generally relates to natural killer cells (NK) and genetically modified NK cells, methods of transformation, and methods of use in combination with other molecules for targeting cells of interest.

Abstract: The present disclosure generally relates to a composition matter and a method for cancer treatment. In particular, a composition of soft, non-cationic nanocapsules, termed Nanosac, for systemic delivery of siRNA. Nanosac is produced by sequential attachment of siRNA and polydopamine on a sacrificial MSN core, followed by removal of the MSN. Encapsulating siRNA in the capsules, Nanosac avoids the issues common to cationic gene carriers, such as toxicity and non-specific protein binding while protecting siRNA from RNase. Nanosac entered tumor cells by caveolae-mediated endocytosis, likely via albumin recruited from serum, trafficked to the cytosol, and silenced target genes.

Abstract: A system and method for determining the locations and types of objects in a plurality of videos. The method comprises pairing each video with one or more sentences describing the activity or activities in which those objects participate in the associated video, wherein no use is made of a pretrained object detector. The object locations are specified as rectangles, the object types are specified as nouns, and sentences describe the relative positions and motions of the objects in the videos referred to by the nouns in the sentences. The relative positions and motions of the objects in the video are described by a conjunction of predicates constructed to represent the activity described by the sentences associated with the videos.

Abstract: A thin-film thermoelectric generator including flexible base film substrate having a longitudinal direction and a transverse direction perpendicular to the longitudinal direction. Thermoelectric (TE) elements are located on the base film substrate. The TE elements arranged in columns oriented along the longitudinal direction of the base film substrate and rows oriented along the transverse direction of the base film substrate. Line grooves are located between at least portion of the rows of the TE elements and extending across the base film substrate in the transverse direction to provide flexibility to the thin-film thermoelectric generator.

Abstract: A radio frequency transmission system and methods for mitigating multipath radio frequency interference are disclosed. Embodiments include a first helical antenna having a first radius and operable to receive a first electromagnetic signal, and a second helical antenna having a second radius and operable to receive a second electromagnetic signal. Further embodiments include a phase adjuster configured to receive the first electromagnetic signal as an input signal, apply an adjustable phase delay to the input signal, and output an adjusted electromagnetic signal. Still further embodiments include a signal combiner configured to receive the adjusted electromagnetic signal and the second electromagnetic signal and output a combined electromagnetic signal.

Abstract: A biological sensing system, comprising a microelectrode array having a plurality of islands that are thermally isolated from each other and are interconnected by flexible nano-scale wires. An embedded complementary metal oxide semiconductor (CMOS) instrumentation amplifier and wireless communication circuitry may be operatively connected to the microelectrode array and embedded within input/output pads connected to the wires at the periphery of the array.

Abstract: A method of depositing a multiphase material. The method includes providing a Continuous Multifunctional Composite (CMC) phase containing at least one continuous element in a polymeric matrix, passing the CMC phase through a feeding system containing a cutting system, producing a predetermined length of the CMC phase, providing a flow a molten polymer such that the molten polymer and the CMC phase are merged into a continuous co-extrusion nozzle so as to produce a co-extruded multiphase material, and depositing the co-extruded multiphase material onto a surface. An apparatus for depositing a multiphase material. The apparatus contains a co-extrusion nozzle, a means to introduce a CMC phase and a molten polymer into the co-extrusion nozzle, such that the molten polymer and the CMC phase are co-extruded and deposited on a surface. An article containing a CMC phase containing continuous elements embedded in a polymer resin forming a multiphase structure.

Abstract: Triboelectric nanogenerators are provided that are textile-based, combine embroidery, silanizing agents, highly networked conductive nanoparticles, and a conformable electronegative layer, and can produce a stable energy source with high power density. Electronic textiles are also provided that utilize such triboelectric nanogenerators to convert the biomechanical energy of a wearer into electrostatic energy that can power electronic devices coupled with the triboelectric nanogenerator. Methods of manufacturing the triboelectric nanogenerators and related electronic textiles are also provided.

Abstract: In some examples, a non-transitory computer-readable medium stores executable code, which, when executed by a processor, causes the processor to receive a video of at least part of a human torso, use a neural network to produce multiple vector fields based on the video, the multiple vector fields representing movement of the human torso, and determine a respiration rate of the human torso using the multiple vector fields.

Abstract: The invention generally relates to systems and methods for increasing reaction yield. In certain embodiments, the invention provides systems for increasing a yield of a chemical reaction that include a pneumatic sprayer configured to generate a liquid spray discharge from a solvent. The solvent includes a plurality of molecules, a portion of which react with each other within the liquid spray discharge to form a reaction product. The system also includes a collector positioned to receive the liquid spray discharge including the unreacted molecules and the reaction product. The system also includes a recirculation loop connected from the collector to the pneumatic sprayer in order to allow the unreacted molecules and the reaction product to be recycled through the pneumatic sprayer, thereby allowing a plurality of the unreacted molecules to react with each other as the unreacted molecules cycle again through the system.

Abstract: The invention generally relates to sample analysis systems and methods of use thereof. In certain aspects, the invention provides a system for analyzing a sample that includes an ion generator configured to generate ions from a sample. The system additionally includes an ion separator configured to separate at or above atmospheric pressure the ions received from the ion generator without use of laminar flowing gas, and a detector that receives and detects the separated ions.

Abstract: Inhibitors of SARS-CoV-2 (COVID), pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.

Abstract: The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.

Abstract: A woven structure includes thermoelectric ribbons interwoven with thread. Each thermoelectric ribbon includes a folded matrix of thermoelectric elements, the matrix having an insulating substrate that supports plural rows of thermoelectric elements, a plurality of conductive elements, and two terminals. The conductive elements form a series connection of the thermoelectric elements between the two terminals. A set of first conductive elements have a first temperature and a set of second conductive contacts have a second temperature lower than the first temperature when a first current flows in a first direction between the first matrix terminal and the second matrix terminal. The folded matrix is configured to form spaced-apart alternating stacks of the first conductive contacts and second conductive contacts. Each length of the yard or thread is interwoven such that it passes alternately under stacks of first conductive contacts and over stacks of second conductive contacts.

Abstract: The present disclosure generally relates to compositions comprising substrate-free 2D tellurene crystals, and the method of making and using the substrate-free 2D tellurene crystals. The 2D tellurene crystals of the present disclosure are characterized by an X-ray diffraction pattern (CuK? radiation, ?=1.54056 A) comprising a peak at 23.79 (2?±0.1°) and optionally one or more peaks selected from the group consisting of 41.26, 47.79, 50.41, and 64.43 (2?±0.1°).

Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.

Abstract: The present disclosure relates to a novel cellulose nanomaterial (CN) based waterborne polyurethane coating, and to methods of making and using the novel cellulose nanomaterial (CN) based waterborne polyurethane coating.

Abstract: A method of performing magnetic resonance spectroscopic imaging (MRSI) measures neurochemical profiles over larger regions non-invasively. The method includes transmitting a multi-slice excitation pulse through tissue, the multi-slice excitation pulse configured to generate multi-slice MRSI signals. The method also includes performing density weighted concentric ring acquisition on the multi-slice MRSI signals. The method further includes receiving the generated multi-slice MRSI signals in a plurality of sensors disposed in various locations around the tissue. Imaging data is reconstructed based on the acquired imaging signals. A representation of the data is displayed.

Abstract: Examples of methods for image enhancement are described. In some examples, a method includes segmenting an image into an object region and a background region. In some examples, the image has a first resolution. In some examples, the method includes generating, using a first machine learning model, an enhanced object region with a second resolution that is greater than the first resolution. In some examples, the first machine learning model has been trained based on object landmarks. In some examples, the method includes generating, using a second machine learning model, an enhanced background region with a third resolution that is greater than the first resolution. In some examples, the method includes combining the enhanced object region and the enhanced background region to produce an enhanced image.

Abstract: A metal-ion deposition regulator to regulate the flux and deposition of metal ions in an electrochemical cell. The regulator containing two membranes made of a polymer and a plurality of two-dimensional porous nanosheets sandwiched between the two membranes. The regulator is capable of distributing flux of metal ions passing through the metal-ion deposition regulator and regulating the deposition of the metal ions onto the cathode or anode thereby suppressing dendrite growth in the electrochemical cell. An electrochemical cell containing an anode, a cathode, a liquid electrolyte, and a metal-ion deposition regulator. A method of making a metal-ion deposition regulator. The method includes fabricating two-dimensional porous nanosheets utilizing graphene oxide as an expendable template, and sandwiching the porous nanosheets between two membranes made of a polymer such that the nanosheets are in contact with the two membranes.