Abstract: Target-specific hybrid capture (TSHC) provides a nucleic acid detection method that is not only rapid and sensitive, but is also highly specific and capable of discriminating highly homologous nucleic acid target sequences. The method produces DNA:RNA hybrids which can be detected by a variety of methods.
Type:
Grant
Filed:
November 7, 2005
Date of Patent:
October 13, 2009
Assignee:
Qiagen Gaithersburg, Inc.
Inventors:
Irina Nazarenko, Attila Lorincz, Paul Eder, Brian Lowe, Richard Mallonee, Ha Thai