Patents Assigned to Research Development Foundation
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Patent number: 12217884Abstract: Protein based highly stretchable compositions with ionic conductivity are disclosed herein. Methods for preparing such compositions are also disclosed.Type: GrantFiled: October 29, 2020Date of Patent: February 4, 2025Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Nadav Amdursky, Ramesh Nandi
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Publication number: 20250027868Abstract: An atomic interferometer system comprises optical tweezers each configured to trap at least one atom therein, an atom source system configured to release atoms, and a controller configured to control the optical tweezers to trap at least one atom released by the atom source system in one of the tweezers, to spatially split a wave function of the trapped atom between at least two of the tweezers, and to at least partially recombine the split atomic wave function in at least one of the tweezers. The atomic interferometer system can also comprise a measuring system configured to measure wavefunction population in each of the tweezers and to display an output pertaining to the wavefunction populations.Type: ApplicationFiled: July 17, 2024Publication date: January 23, 2025Applicant: Technion Research & Development Foundation LimitedInventor: Yoav SAGI
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Patent number: 12201386Abstract: Systems and methods for performing minimally invasive surgical procedures, especially for removal of tumors, and especially for brain tumors, using a robotically inserted therapeutic probe, which first detects tumorous tissue on a pre-planned path through the patient's tissue, before performing therapeutic procedures on the tissue, such as ablation. This pre-treatment detection procedure is thus able to avoid the destruction of healthy tissue. This also ensures that the therapeutic process indicated in a preoperative surgical plan is only performed on tumorous tissue, without sole reliance on preoperative image indications. This is important for neurosurgical operations performed on the brain, since preoperative images may not be accurate due to brain shift occurring during the procedure. Detection can be performed optically or ultrasonically, and treatment by laser or RF ablation. The probe insertion can be performed at 90° to the insertion axis of the device, thus minimizing passage through healthy tissue.Type: GrantFiled: September 6, 2018Date of Patent: January 21, 2025Assignee: Technion Research & Development Foundation LimitedInventors: Hadas Ziso, David Zarrouk, Moshe Shoham, Menashe Zaaroor
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Patent number: 12201628Abstract: A method for modulating an immune response by activating or inhibiting dopaminergic neurons in the Ventral Tegmental Area (VTA) is provided. Modulation is achieved by modulating the activity, the abundance or both of: a natural killer cell, a CD8 T-cell, a CD4 T-cell, a B-cell, a dendritic cell, a macrophage, a granulocyte, or their combination.Type: GrantFiled: September 19, 2022Date of Patent: January 21, 2025Assignees: TECHNION RESEARCH &DEVELOPMENT FOUNDATION LIMITED, HEALTH CORPORATION—RAMBAMInventors: Asya Rolls, Tamar Ben Shannan, Hilla Azulay-Debbie, Fahed Hakim, Maya Schiller, Shai Shen-Orr, Elina Starosvetsky
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Patent number: 12196699Abstract: The present invention relates to a chemically sensitive sensor for detecting volatile organic compounds, the sensor comprising a substrate, an electrode array, a micro-barrier, and a sensing layer comprising a multiplicity of core-shell particles in close-packed orientation, the particles comprising a metal nanoparticle (MNP) core and an organic ligand shell, wherein the MNP core has a mean particle size below about 15 nm. The invention further provides a method for fabrication of the chemically sensitive sensor.Type: GrantFiled: October 30, 2019Date of Patent: January 14, 2025Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Hossam Haick, Yana Milyutin, Gidi Shani, Manal Abud Hawa
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Patent number: 12189762Abstract: A system, a method and a computer program product for protecting a speculative execution processor from side channel attacks, are disclosed. The system comprises a processing circuitry which performs an execution of a code segment, in one time period and copies, in another time period, only a committed portion of the executed code segment into a memory component which is accessible to read actions by an external processing unit. The speculative instructions are stored in an internal cache memory which is not accessible to read actions by the external processing unit.Type: GrantFiled: June 19, 2020Date of Patent: January 7, 2025Assignee: Technion Research & Development Foundation LimitedInventor: Abraham Mendelson
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Patent number: 12186454Abstract: A scaffold comprising electrospun decellularized ECM of an organ, wherein the decellularized ECM has a similar protein composition to native ECM of the organ. Methods of generating same are also disclosed as well as uses of same.Type: GrantFiled: January 23, 2023Date of Patent: January 7, 2025Assignee: Technion Research & Development Foundation LimitedInventors: Marcelle Machluf, Eyal Zussman, Limor Baruch
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Patent number: 12182690Abstract: A stochastic synapse for use in a neural network, comprising: first and second magnetic tunnel junction (MTJ) devices, each MTJ device having a fixed layer port and a free layer port; a first and second control circuit, each connected respectively to the free layer port of the first and second MTJ devices, wherein the fixed layer ports of the first and second MTJ devices are connected to each other; wherein the first and second control circuits are configured to perform a gated XNOR operation between synapse and activation values; and wherein an output of the gated XNOR is represented by the output current through both of the first and second MTJ devices.Type: GrantFiled: December 7, 2020Date of Patent: December 31, 2024Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Tzofnat Greenberg, Shahar Kvatinsky, Daniel Soudry
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Publication number: 20240425938Abstract: This disclosure relates to methods and compositions useful for detecting and monitoring low-frequency mutations. Methods and compositions described herein can be used to guide clinical decisions, for example, by informing on which antibiotics should be avoided, or conversely, which antibiotics should be actively used in the case of compounds that select against a specific type of resistance.Type: ApplicationFiled: August 9, 2024Publication date: December 26, 2024Applicants: The Broad Institute, Inc., The Children's Medical Center Corporation, Technion Research & Development Foundation LimitedInventors: Gregory P. PRIEBE, Roy KISHONY, Hattie CHUNG, Matthew M. SCHAEFERS
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Publication number: 20240424075Abstract: Immunoreactive engineered polypeptides are provided. The engineered polypeptides can be used to diagnose or induce an immune response against E. chaffeensis or E. canis.Type: ApplicationFiled: June 26, 2024Publication date: December 26, 2024Applicant: Research Development FoundationInventors: Jere McBRIDE, David WALKER
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Patent number: 12171545Abstract: A robotic shoe which provides real-time feedback regarding forces acting on the foot of the user, in order to modify these forces in a corrective or diagnostic manner. The shoe comprises an insole equipped with embedded pressure sensors enabling it to continuously monitor the ground reaction forces (GRF) and the foot center of pressure (COP) while the user is standing, walking, and running. The insole COP and GRF readings are input to a programmable system that shifts the COP trajectory dynamically in a patient-specific manner via the robotic platform of the shoe. The robotic platform contains motors that control elements whose movement manipulates the forces acting on the foot and lower limb, resulting in modification of the GRF. Closed loop feedback enables a dynamic fit of an optimal COP. The COP and GRF information can be stored for analysis and diagnosis of gait and instability events accruing during locomotion.Type: GrantFiled: June 1, 2020Date of Patent: December 24, 2024Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.Inventors: Alon Wolf, Hadar Shaulian
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Patent number: 12171568Abstract: The present invention is directed to a method for inducing an immune response in a subject, including a step of activating neurons in the mesolimbic network of the subject by applying a neurofeedback.Type: GrantFiled: March 3, 2020Date of Patent: December 24, 2024Assignees: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED, ICHILOV TECH LTD., RAMOT AT TEL-AVIV UNIVERSITY LTD.Inventors: Talma Hendler, Asya Rolls, Nitzan Lubianiker, Tamar Koren, Neomi Singer, Tamar Ben Shannan, Shai Shen Orr, Fahed Hakim, Hilla Azulay-Debby, Rani Cohen
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Patent number: 12171408Abstract: Exemplary embodiments of the present disclosure include systems and methods for treatment of occlusions, including coronary artery chronic total occlusions.Type: GrantFiled: November 28, 2022Date of Patent: December 24, 2024Assignee: Research Development FoundationInventors: Marc D. Feldman, Thomas E. Milner, Nitesh Katta, Arnold Estrada, Meagan Oglesby, Andrew Giles Cabe, Mehmet Cilingiroglu
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Publication number: 20240415372Abstract: An assembly for driving linear movement and roll movement of an elongate surgical tool, comprising: an elongate shaft comprising a central lumen extending along the shaft long axis; the elongate shaft comprising a plurality of apertures extending across walls of the elongate shaft and into the central lumen; a set of wheels positioned opposing each other and aligned on two sides of the central lumen, the set of wheels at least partially extending through the apertures beyond the walls of the elongate shaft and into the central lumen to contact an elongate surgical tool received therein; the set of wheels being coupled to the elongate shaft and configured to rotate with the elongate shaft as a single unit when the elongate shaft is rotated about the shaft long axis.Type: ApplicationFiled: August 23, 2024Publication date: December 19, 2024Applicants: Microbot Medical Ltd., Technion Research & Development Foundation LimitedInventors: Simon SHARON, Idan BOADER, Moshe SHOHAM, Eran COHEN, Eyal MORAG
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Patent number: 12168265Abstract: Systems comprising a light source, thin membrane immersed in an aqueous solution and a system to direct and focus light from the light source to a spot on the membrane are provided. Methods of thinning and etching a membrane are also provided, as are membranes comprising a nanopore with a Gaussian curve shaped cross-section.Type: GrantFiled: September 23, 2021Date of Patent: December 17, 2024Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Amit Meller, Tal Gilboa, Adam Zrehen, Arik Girsault, Eran Zvuloni
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Publication number: 20240408791Abstract: Disclosed is a method of fabricating a construction element. The method may include assembling a mold on a rotational casting machine; rotating the mold around at least two axes at a predetermined speed; providing a first portion of magnesium silico-phosphate cement (MSPC) mix, having an altered hardening rate, to the mold while rotating the mold until at least a portion of the mold's walls is covered by a first layer of the MSPC mix; and rotating the mold until the MSPC mix is hardened to a predetermined degree.Type: ApplicationFiled: August 20, 2024Publication date: December 12, 2024Applicant: Technion Research & Development Foundation LimitedInventors: Ryan POURATI, Pavel Larianovsky, Arnon Ben Tur, Jacob Grobman, Tom Shaked, Aaron Sprecher, Aharon Weissman, Bassam Masri
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Patent number: 12163120Abstract: A method of preparing a composition comprising mycelium along with a cellulose and/or plurality of nanoparticles is described herein. The method comprises inoculating a liquid medium with fungus, the liquid medium comprising nutrients and the cellulose and/or nanoparticles. Further described herein are compositions comprising mycelium along with a cellulose and/or plurality of nanoparticles, as well as articles-of-manufacture comprising such a composition, wherein at least 10% of the cellulose and/or nanoparticles in the composition is incorporated within the mycelium. A method of enhancing fungal growth is also described, comprising contacting the fungus with a liquid medium comprising a polymer which comprises carboxylic acid groups.Type: GrantFiled: September 10, 2021Date of Patent: December 10, 2024Assignee: Technion Research & Development Foundation LimitedInventors: Noam Attias, Jacob Grobman, Tiffany Abitbol
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Patent number: 12165070Abstract: An analog signal processing circuit comprising: a first promoter operably linked to a nucleic acid sequence encoding a first output molecule, wherein said promoter is responsive to a cooperative input signal comprising at least two cooperative inputs, and wherein expression of said at least two cooperative inputs is tunable.Type: GrantFiled: June 27, 2018Date of Patent: December 10, 2024Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITEDInventors: Ramez Daniel, Loai Danial
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Publication number: 20240401517Abstract: A hybrid system, including a solid-oxide fuel cell (SOFC), an internal combustion engine (ICE), and a thermochemical recuperation (TCR) unit. The TCR unit is configured to: (i) receive waist heat from the ICE, (ii) receive a primary fuel, (iii) perform a waste heat recovery process to provide reformed fuel. The SOFC is configured to receive a first part of the reformed fuel and convert the first part of the reformed fuel to electrical work. The ICE is configured to receive a second part of the reformed fuel and convert the second part of the reformed fuel to mechanical work.Type: ApplicationFiled: April 30, 2024Publication date: December 5, 2024Applicant: Technion Research & Development Foundation LimitedInventors: David Diskin, Leonid Tartakovsky
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Patent number: 12159663Abstract: A static random-access memory (SRAM) cell includes a first inverter and a second inverter being cross-coupled; a first access transistor that accesses an output of the first inverter under control of a word line; a second access transistor that accesses an output of the second inverter under control of the word line; a first passage transistor that passes a common-mode voltage, controlled by the output of the first inverter; a second passage transistor that passes an input signal, controlled by the output of the second inverter; and a capacitor switchably coupled to receive the common-mode voltage and the input signal through the first passage transistor and the second passage transistor respectively.Type: GrantFiled: December 28, 2023Date of Patent: December 3, 2024Assignees: NCKU Research and Development Foundation, Himax Technologies LimitedInventors: Wei-Li He, Soon-Jyh Chang