Abstract: Novel agents exhibiting anti-biofilm formation activity while being non-cytotoxic are provided, as well as methods of using the same, either per se or conjugated to a polymer, for preventing and/or reducing the formation of microbial biofilms and/or for disrupting microbial biofilms. The novel agents described herein include thiazolidine-2,4-diones (TZDs), pyrrolidine-2,5-diones (PYDs), imidazolidine-2,4-diones or oxazolidine-2,4-diones, substituted by an alkyl having 7-20 carbon atoms in its backbone chain.

Abstract: The present invention relates to abrasive grains, which are coated with a micro-particle inorganic powder and a binder, consisting of the group of conventional abrasive grains as well as the group of the “superabrasives”, wherein the binder comprises an aluminosilicate with a molar ratio of Al2O3 to SiO2 of 1:2 to 1:20 as well as at least one complex alkaline fluoride. The particular advantage of this coating is that the binder can already be completely hardened at below 400° C. The invention also relates to a method for producing such abrasive grains as well as to the use thereof for producing abrasives.

Abstract: In one embodiment, the invention provides a method of treating, reducing the incidence, reducing the severity or pathogenesis of an eye disease or disorder in a subject, including, inter alia, retinal detachment, macular degeneration, glaucoma or retinopathy, comprising the step of administering an effective amount of a lipid or phospholipid moiety bound optionally via a spacer to a physiologically acceptable monomer, dimer, oligomer, or polymer via an ester or amide bond, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof. This invention also provides a contact lens solution comprising a lipid or phospholipid moiety bound optionally via a spacer to a physiologically acceptable monomer, dimer, oligomer, or polymer via an ester or amide bond, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof.

Abstract: The present invention provides plant inbred mutant parent lines producing hybrid offspring having at least one heterosis-related phenotype, particularly total yield associated phenotypes, methods for identifying same and hybrid plants produced therefrom. The present invention further discloses heterosis-related genes and provides the corresponding isolated polynucleotides.

Abstract: A method of separating a mixture of a plurality of molecular analytes having different isoelectric points (pIs). The method comprises placing a solution containing a mixture of a plurality of molecular analytes in a separation volume, generating a pH profile having a plurality of pH zones across an axis of the separation volume, and adjusting a profile of the pH profile to induce a migration of a first molecular analyte along the axis apart from a second molecular analyte. The first and second molecular analytes having different pIs.

Abstract: A method and system (30) generates an output image (21) of increased pixel resolution from an input image (20), which is non-dyadically upscaled to generate an upscaled image (22) having more pixels than the input image and is low-pass filtered to generate a smoothed image (23). A high detail image (24) is generated by subtraction and for each pixel in the upscaled image, a patch (25) containing the pixel is identified. A best-fit patch (26) within a localized region (27) of the smoothed image is found by searching in the smoothed image in close proximity to a mapped location of the patch in the upscaled image. Each pixel in the patch of the upscaled image is corrected by uniquely adding the value of the corresponding pixel in an equivalent patch of the high detail image corresponding to the best-fit patch, and the corrected upscaled image is stored for further processing.

Abstract: A touch screen, now incorporated in most smart phones, presents an effective and transparent method to incorporate continuous active user verification schemes. The projected capacitive grid structure can be used to capture enough information to verify that a valid user currently has possession of the mobile device, even while the user is not consciously engaged in an active verification interface. Further processing, such as habitual gesture recognition, can augment the process.

Abstract: An apparatus includes an optical ring resonator, first and second optical couplers, and control circuitry. The first optical coupler is configured to modulate an input optical signal traversing an optical waveguide, by tuning cross-coupling of energy between the optical waveguide and the ring resonator with a first variable coupling coefficient. The second optical coupler is configured to tune cross-coupling of energy between the ring resonator and an auxiliary optical signal, different from the input optical signal, with a second variable coupling coefficient. The control circuitry is configured to modulate the first coupling coefficient with a first control signal so as to modulate the input optical signal, and to modulate the second coupling coefficient with a second control signal, so as to retain a constant electrical-field complex envelope in the ring resonator.

Abstract: The present application is directed to a novel composition which acts as a barrier to noxious agents while adding self-detoxifying catalytic treatments to neutralize the noxious and harmful warfare agents when applied for example on a fabric, or other solid support.

Abstract: Dialysis systems comprising actuators that cooperate to perform dialysis functions and sensors that cooperate to monitor dialysis functions are disclosed. According to one aspect, such a hemodialysis system comprises a user interface model layer, a therapy layer, below the user interface model layer, and a machine layer below the therapy layer. The user interface model layer is configured to manage the state of a graphical user interface and receive inputs from a graphical user interface. The therapy layer is configured to run state machines that generate therapy commands based at least in part on the inputs from the graphical user interface. The machine layer is configured to provide commands for the actuators based on the therapy commands.

Abstract: This invention provides a method of treating, suppressing, inhibiting, or preventing chronic rhinosinusitis in a subject comprising the step of administering to a subject a compound comprising a lipid or phospholipid moiety bond to a physiologically acceptable monomer, dimer, oligomer, or polymer, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof. This invention also provides a method of treating, suppressing, inhibiting, or preventing nasal polyps in a subject comprising the step of administering to a subject a compound comprising a lipid or phospholipid moiety bond to a physiologically acceptable monomer, dimer, oligomer, or polymer, and/or a pharmaceutically acceptable salt or a pharmaceutical product thereof.

Abstract: Provided herein are compositions and methods for use in promoting wound healing and tissue regeneration following tissue injury in a subject.

Abstract: A neural network is disclosed. The neural network comprises a plurality of optogenetically modified neural cells being three-dimensionally distributed in a hydrogel medium and being disconnected from any solid support having a shear modulus above 1 GPa.

Abstract: A method for evaluating the effect of a compound on vasomotor response in vivo comprises the steps of administering said compound to a rabbit and measuring the diameter of the vessel lumen of a central ear artery of said rabbit in comparison with the baseline diameter of the vessel lumen of said central ear artery of said rabbit, said baseline diameter being measured prior to the administration of said compound.

Abstract: An imaging device includes a fixed focus lens, an image sensor having an image matrix of a plurality of pixels arranged on a semiconductor substrate and supplying image data, and an electronic circuit for reading the image matrix. The image sensor also includes at least two ambient light sensors arranged on the semiconductor substrate on opposite sides of the image matrix, and configured to capture an ambient light intensity through the fixed lens, and the electronic circuit is also configured to read the two ambient light sensors and to supply ambient light data and the image data.

Abstract: A method of making engineered tissue from a plurality of cell aggregates is disclosed. A cell suspension is centrifuged. The resulting pellet is extruded through an orifice, and the extruded pellet is cut into pieces to produce cell aggregates. A plurality of the cell aggregates are printed in a pattern, and allowed to fuse to form a desired three-dimensional engineered tissue structure. Modeling methods predict the structural evolution of fusing cell aggregates for combinations of cell type to enable selection of organ printing process parameters for use in producing an engineered tissue having a desired three-dimensional structure.

Abstract: A novel therapy regime/regimen for the treatment of acne related diseases includes administering a topical fixed-dose combination of a retinoid and an anti-bacterial agent, such as BPO, to a course of oral antibiotic therapy.

Abstract: An alignment method for assembling substrates in different spaces without fiducial mark and its system are provided, and the alignment method has steps of: pre-defining partially standard character regions of two substrates; capturing at least two partially actual images of two substrates in different waiting spaces, respectively; comparing to obtain at least two partially actual character regions of the two substrates, respectively; building actual coordinate systems of the two substrates, respectively; comparing the actual coordinate systems of the two substrates with each other to obtain a set of offset values; moving the two substrates from the different waiting spaces to an alignment-and-installation space based on the set of offset values and a predetermined movement value, respectively; and stacking the two substrates with each other to finish the alignment and installation in the alignment-and-installation space.

Abstract: A device (1) for producing an aerosol from vaporizable constituents of tobacco comprises a vaporizing chamber (24) within which the tobacco is placed. A main housing (9) which forms a portion of the vaporizing chamber also forms a combustion chamber (18) within which a gas catalytic combustion element (19) is located for converting fuel gas to heat by catalytic action. A temperature responsive control valve (61) controls the supply of fuel gas to the combustion chamber for maintaining the temperature in the vaporizing chamber A thermal mass (96) secured to a tab portion (95) of the gas catalytic combustion element maintains the temperature of the tab portion at or above the ignition temperature of the gas catalytic combustion element during periods of fuel gas interruption by the control valve. Vaporised constituents of the tobacco are drawn from the vaporizing chamber through an aerosol accommodating tube (37) through a mouthpiece (38).

Abstract: A leaky travelling wave array of optical elements provide a solar wavelength rectenna.