Patents Assigned to Research Development
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Patent number: 8846903Abstract: Novel acyl-urea containing compounds, processes of preparing same, compositions containing same and uses thereof in the treatment of neurological diseases and disorders such as epilepsy, neuropathic pain, bipolar disorder, status epilepticus, chemically-induced convulsions and/or seizure disorders, febrile convulsions conditions, metabolic disturbances and a sustenance withdrawal conditions, are provided. Also provided are uses of these and other acyl-urea containing compounds in the treatment of neurological diseases and disorders.Type: GrantFiled: June 25, 2008Date of Patent: September 30, 2014Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: Meir Bialer, Boris Yagen, Jakob Avi Shimshoni
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Patent number: 8846400Abstract: A cell culture comprising human foreskin cells, the human foreskin cells being capable of maintaining stem cells in an undifferentiated state when co-cultured therewith.Type: GrantFiled: November 26, 2012Date of Patent: September 30, 2014Assignee: Technion Research & Development Foundation LimitedInventors: Michal Amit, Joseph Itskovitz-Eldor
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Publication number: 20140285472Abstract: A sensor includes a linear array of sensitive photodetectors each forming part of an associated pixel circuit. The pixel circuits accumulate photo-generated charge from their photodetectors simultaneously but with different gains for different pixels. Each pixel circuit comprises an operational amplifier arranged to integrate a photocurrent received from the photodetector over a sampling interval that is substantially the same for all pixels. The gain of each pixel circuit is made variable over time by switching one or more capacitors in and out of the integrating circuit. In one embodiment a gain selection signal is written into each pixel circuit during a data read-out cycle. In another embodiment, the gain of each pixel varies automatically in response to data obtained from the pixel in a previous cycle. Several similar sensors are used to detect touch positions in a touch screen input device.Type: ApplicationFiled: March 20, 2014Publication date: September 25, 2014Applicant: STMicroelectronics (Research & Development) LimitedInventor: Jeff Raynor
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Patent number: 8841595Abstract: An image sensor includes an array of pixels. Each pixel has at least one photo-sensitive element. Readout circuitry receives an analog signal from each pixel at a first time and at a second time, between which the analog signal changes. The image sensor further includes associated support circuitry which is a source of time variant noise. The signal level at both first and second times includes pixel noise. Sample and hold circuitry is provided to maintain substantially level at least a proportion of this support circuitry noise time invariant at the sensor output between the first time and the second time.Type: GrantFiled: June 30, 2011Date of Patent: September 23, 2014Assignee: STMicroelectronics (Research & Development) LimitedInventors: Graeme Storm, Matthew Purcell
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Publication number: 20140275536Abstract: The use of compounds in the treatment of skin disorders is described. In particular, use of a compound of formula (I): or one of its pharmaceutically acceptable salts, solvates or hydrates in the preparation of a medicament to treat skin pathologies is described.Type: ApplicationFiled: December 22, 2010Publication date: September 18, 2014Applicant: Galderma Research & DevelopmentInventor: Cédric Poinsard
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Publication number: 20140275492Abstract: The present invention provides for methods of producing human monoclonal antibodies against a wide variety of antigens including bacterial and viral antigens, as well as tumor antigens, and various autoantigens. Also provided are the antibodies themselves, nucleic acids encoding such antibodies, cells producing such antibodies, and methods of using such antibodies for diagnostic assays and passive immunity against disease states such as infection and cancer.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicant: MUSC Foundation for Research DevelopmentInventors: Natalie SUTKOWSKI, Semyon Rubinchik
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Publication number: 20140264500Abstract: A photovoltaic device includes lateral P-I-N light-sensitive diodes disposed on a silicon island formed by a P? epitaxial layer and surrounded by trenches that provide lateral isolation, where the island is separated from the substrate by a porous silicon region that is grown under the island and isolates the lower portions of the photovoltaic device from the highly doped substrate. The trenches extend through the P? epitaxial material into the P+ substrate to facilitate self-limiting porous silicon formation at the bottom of the island, and also to suppress electron-hole recombination. A protective layer (e.g., SiN) is formed on the trench walls to further restrict porous silicon formation to the bottom of the island. Black silicon on the trench walls enhances light capture. The photovoltaic devices form low-cost embedded photovoltaic arrays on CMOS IC devices, or are separated to produce low-cost, HV solar arrays for solar energy sources, e.g. for solar concentrators.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Applicants: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd., Tower Semiconductor Ltd.Inventors: Yakov Roizin, Evgeny Pikhay, Irit Chen-Zamero, Ora Eli, Micha Asscher, Amir Saar
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Publication number: 20140265391Abstract: Disclosed is a new sling bar for use with an overhead lift system to lift a load suspended in a lift sling there below. The sling bar comprises a cross bar having first and second ends, a pair of lift loop retention ears extending from each of the first and second ends of the cross bar. Each pair of ears includes a first ear in the pair being disposed adjacent a first face of the cross bar and a second ear in the pair disposed adjacent a second opposite face of said cross bar, the pair of retention ears defining a space there between. A lift hook is disposed at each of the first and second ends of the cross bar in the space defined between the pair of retention ears, the pair of ears extending at least up to an inner surface of a bend portion of the lift hook.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicant: Liko Research & Development ABInventors: Roger KARLSSON, Ronnie ARESPONG
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Publication number: 20140273332Abstract: Photovoltaic devices are produced using a minimally modified standard process flow by forming lateral P-I-N light-sensitive diodes on silicon islands that are isolated laterally by trenches performed by RIE, and from an underlying support substrate by porous silicon regions. P+ and N+ doped regions are formed in a P? epitaxial layer, trenches are etched through the epitaxial layer into a P+ substrate, a protective layer (e.g., SiN) is formed on the trench walls, and then porous silicon is formed (e.g., using HF solution) in the trenches that grows laterally through the P+ substrate and merges under the island. The method is either utilized to form low-cost embedded photovoltaic arrays on CMOS IC devices, or the devices are separated from the P+ substrate by etching through the porous silicon to produce low-cost, high voltage solar arrays for solar energy sources, e.g., solar concentrators.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Tower Semiconductor Ltd.Inventors: Yakov Roizin, Evgeny Pikhay, Irit Chen-Zamero, Ora Eli, Micha Asscher, Amir Saar
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Publication number: 20140266503Abstract: Dispersive properties of a linear dispersive delay line are retained in a spiral configuration by constraining the radius of curvature depending on a desired propagation mode. The compact form factor spiral can be either a continuous spiral or a piecewise linear approximation. The spiral comprises a highly dielectric waveguide such as titanium dioxide or barium tetratitanate. Preferably, a spacer with a low dielectric constant and a microstrip are disposed on the top surface. The microstrip prevents attenuation of low frequencies, thereby increasing the operating frequency range. A second dielectric spacer and a second microstrip can be deposited on the bottom surface of the waveguide. Alternatively, the bottom surface of the waveguide can face a ground plane. The waveguide can be fed by horns or half-horns.Type: ApplicationFiled: March 13, 2014Publication date: September 18, 2014Applicant: AMI Research & Development, LLCInventors: John T. Apostolos, William Mouyos, Benjamin McMahon
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Publication number: 20140259391Abstract: A patient lift system includes a lift housing, a base lift strap having a first end coupled to a lift housing and a second end coupled to a sling bar. The base lift strap is infection controlled. In one embodiment, a protective sleeve covers the base lift strap, wherein the protective sleeve has a first end and a second end. In another embodiment, the base lift strap is chemically treated to provide infection control.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: Liko Research & Development ABInventors: Roger KARLSSON, Mattias ANDERSSON, Lars EKLOF, Laetitia GAZAGNES, Josh SHENK
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Publication number: 20140266209Abstract: A system that uses the nuclear quadrupole resonant effect to detect the presence of materials of interest, such as may be excited by radio frequency fields generated within a portal. Transmitted chirp signals may be processed using matching filtering and other signal processing to accurately detect the presence of such materials.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicant: AMI Research & Development, LLCInventors: John T. Apostolos, Judy Feng, William Mouyos
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Patent number: 8835060Abstract: Silicon-oxygen batteries comprising a silicon anode as chemical fuel, an air-cathode for dissociating oxygen, and an electrolyte, and applications using the same are provided. The silicon-batteries may utilize air for generating oxygen.Type: GrantFiled: February 11, 2010Date of Patent: September 16, 2014Assignees: Technion Research & Development Foundation Limited, The Penn State Research FoundationInventors: Yair Ein-Eli, Digby Donald MacDonald
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Patent number: 8834588Abstract: The present invention relates to polycrystalline Al2O3 bodies based on melted aluminum oxide having a mean crystallite size of the primary crystals between 20 ?m and 100 ?m and a closed macroporosity between 10% by volume and 30% by volume. The polycrystalline Al2O3 bodies may be obtained by tapping out and quenching a liquid aluminum oxide melt and simultaneous seeding of the pouring stream with seed crystals and can be used advantageously for the production of abrasive materials and refractory products.Type: GrantFiled: August 15, 2011Date of Patent: September 16, 2014Assignee: Center for Abrasives and Refractories Research & Development C.A.R.R.D. GmbHInventor: Sebastian Sachse
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Patent number: 8838998Abstract: A method distributes personalized circuits to one or more parties. The method distributes a generic circuit to each party, encrypts a unique personalization value using a secret encryption key, and transmits each encrypted personalization value to the corresponding party. Each party then stores the encrypted personalization value in their circuit. The stored encrypted personalization value allows a piece of software to be properly executed by the circuit. A semiconductor integrated circuit is arranged to execute a piece of software that inputs a personalization value as an input parameter. The circuit comprises a personalization memory arranged to store an encrypted personalization value; a key memory for storing a decryption key; a control unit comprising a cryptographic circuit arranged to decrypt the encrypted personalization value using the decryption key; and a processor arranged to receive the decrypted personalization value and execute the software using the decrypted personalization value.Type: GrantFiled: January 25, 2013Date of Patent: September 16, 2014Assignee: STMicroelectronics (Research & Development) LimitedInventor: Andrew Dellow
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Patent number: 8834848Abstract: A drug and device combination system used in a method for treatment of patients suffering from severe and oral corticosteroid-dependent asthma and other respiratory diseases requiring a treatment with orally administered steroids. The method for administration of the inhalable corticosteroid by a flow rate and volume regulated inhalation. The combination system of the inhalable corticosteroid and the device for regulating flow rate and volume of the inhalable corticosteroid and thus achieving delivery of said inhalable corticosteroid into the small airways of the lungs. The individually programmable device that assures safe and reproducible corticosteroid delivery compliant with treatment protocol.Type: GrantFiled: September 6, 2012Date of Patent: September 16, 2014Assignee: Activaero GmbH Research & DevelopmentInventors: Bernard Muellinger, Gerhard Scheuch, Thomas Hofmann, Philipp Kroneberg
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Patent number: 8835145Abstract: The invention relates to a thrombolytic enzyme referred to as Thrombinase having a molecular weight of 31,000 to 32,000. Such a thrombolytic enzyme can be used for dissolving blood clots. The process comprises culturing a filtrate of Bacillus sphaericus sero type H5a 5b, removing the cell, subjecting the cell supernatant to filtration, salting out the retentate, subjecting the precipitate to dialysis, reprecipitating the precipitate and then reconstituting in buffer and finally decolorizing, purifying and dialyzing.Type: GrantFiled: October 12, 2007Date of Patent: September 16, 2014Assignees: National Research Development Corporation, India and Malladi Drugs Pharmaceuticals Ltd.Inventors: Subrahamanyam Chivukula Sekar, Sundaramurthy Suresh Babu, Sita Mahadevan
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Patent number: 8836557Abstract: A method for signal processing includes accepting an analog signal, which consists of a sequence of pulses confined to a finite time interval. The analog signal is sampled at a sampling rate that is lower than a Nyquist rate of the analog signal and with samples taken at sample times that are independent of respective pulse shapes of the pulses and respective time positions of the pulses in the time interval. The sampled analog signal is processed.Type: GrantFiled: October 5, 2011Date of Patent: September 16, 2014Assignee: Technion Research & Development Foundation Ltd.Inventors: Yonina Eldar, Ewa Matusiak
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Publication number: 20140256641Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.Type: ApplicationFiled: March 13, 2014Publication date: September 11, 2014Applicants: CollPlant Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: Oded SHOSEYOV, Shaul Lapidot, Sigal Meirovitch, Daniel L. Siegel
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Publication number: 20140256645Abstract: The invention relates to isolated peptides derived from Oryza sativa Japonica Group, pharmaceutical compositions comprising same, and uses thereof for treating, preventing, ameliorating, and/or delaying the onset of inflammatory and/or neuroinflammatory and/or autoimmune diseases or conditions and in particular multiple sclerosis. The invention further relates to extracts from Oryza sativa Japonica Group and use thereof as a dietary supplement or in a pharmaceutical composition for treating, preventing, ameliorating, and/or delaying the onset of inflammatory, and/or inflammatory, neuroinflammatory and/or autoimmune diseases or conditions. The peptides and the extract of the invention may be used for treating, ameliorating, and/or delaying the onset or preventing multiple sclerosis.Type: ApplicationFiled: May 19, 2014Publication date: September 11, 2014Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem LTD.Inventor: Uri WORMSER