Patents Assigned to Research Development
  • Patent number: 5304586
    Abstract: One component, visible light-cured dental restorative compositions having fluoride release properties for the purpose of reducing the chances of secondary caries are provided. The compositions include inorganic particulate fluoride leachable glass.
    Type: Grant
    Filed: August 2, 1991
    Date of Patent: April 19, 1994
    Assignee: Dentsply Research & Development Corp.
    Inventors: Paul D. Hammesfahr, Paul S. Danielson, Robert C. Campbell
  • Patent number: 5300859
    Abstract: A source of IR-radiation, having an enclosure defining between its walls a sealed-off, electrode-less chamber, the walls having at least one portion transparent to IR-radiation, and the chamber containing a gas mixture of at least one, molecular, IR-active gas, of at least one buffer gas and of at least one noble gas. A method for producing a source of IR-radiation is also described and claimed.
    Type: Grant
    Filed: March 19, 1991
    Date of Patent: April 5, 1994
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Shaul Yatsiv, Amnon Gabay
  • Patent number: 5300564
    Abstract: A method is proposed of obtaining a chemical interaction between at least one reagent trapped in sol-gel glass by doping it with the reagent, and diffusible solutes or components in an adjacent liquid or gas phase. The reagents, the solutes or the components can be any organic or inorganic compounds or materials of biological origin including enzymes. The doped sol-gel glass in various forms may be useful as analytical test, chromatographic medium, sensor, catalyst or biocatalyst, electrode or enzyme electrode, or other detection device.
    Type: Grant
    Filed: January 8, 1991
    Date of Patent: April 5, 1994
    Assignee: YISSUM, Research Development Company of the Hebrew University of Jerusalem
    Inventors: David Avnir, Michael Ottolenghi, Sergei Braun, Rivka Zusman
  • Patent number: 5300495
    Abstract: Sulpinine C, secopenitrem B and 10-oxo-11,33-dihydropenitrem B indole compounds have been isolated from the sclerotia of the fungi Aspergillus sulphureus. Aflatrem B has been isolated from the sclerotia of the fungi Aspergillus flavus, and 14-hydroxypaspalinine and 14-(N,N-dimethylvalyloxy)paspalinine have been isolated from the sclerotia of the fungi Aspergillus nomius. The indole compounds are effective for controlling Coleopteran and Lepidopteran insects.
    Type: Grant
    Filed: January 22, 1993
    Date of Patent: April 5, 1994
    Assignees: The United States of America, as represented by the Secretary of Agriculture, University of Iowa Research Foundation, Biotechnology Research & Development Corporation
    Inventors: Jodi A. Laakso, Patrick F. Dowd, James B. Gloer, Donald T. Wicklow
  • Patent number: 5298758
    Abstract: An apparatus and method for curing light curable material using unfiltered light. A vented housing encloses a single lamp filament light source which emits visible light. The light source is positioned above and to the side of the light curable material which is supported on a rotating table during light curing. Light incident to the surface of the light curable material is at least about 50 milliwatts per square centimeter. The light curable material has a surface temperature of at least 150.degree. F. (65.6.degree. C.) after 2 minutes.
    Type: Grant
    Filed: December 7, 1992
    Date of Patent: March 29, 1994
    Assignee: Dentsply Research & Development Corp.
    Inventors: Louis H. Tateosian, Duane E. Barber
  • Patent number: 5296403
    Abstract: A semiconductor device comprises a vertical MIS-SIT which has a smaller source-to-drain distance for operation at ultra-high speed. The semiconductor device has a substrate crystal for epitaxial growth thereon, least two semiconductor regions of different conductivity types deposited by way of epitaxial growth on the substrate crystal according to either metal organic chemical vapor deposition (MO-CVD) or molecular layer epitaxy (MLE), thereby providing a source-drain structure, a gate side formed by etching the semiconductor regions of the source-drain structure, the gate side comprising either a (111)A face or a (111)B face, and a semiconductor region deposited as a gate by way of epitaxial growth on the gate side according to either MO-CVD or MLE.
    Type: Grant
    Filed: October 23, 1992
    Date of Patent: March 22, 1994
    Assignees: Research Development Corp. of Japan, Jun-ichi Nishizawa, Zaidan Hojin Handotai Kenkyu Shinkokai
    Inventors: Jun-ichi Nishizawa, Toru Kurabayashi
  • Patent number: 5296371
    Abstract: The present invention is directed to a method for cloning and producing the Spiroplasma sp. strain MQ1 DNA methylase by (1) introducing the Spiroplasma methylase gene into a host whereby the methylase gene is expressed; (2) fermenting the host which contains the vector encoding and expressing the Spiroplasma methylase and (3) purifying the Spiroplasma methylase from the fermented host which contains the vector encoding and expressing the Spiroplasma DNA methylase activity.
    Type: Grant
    Filed: October 4, 1991
    Date of Patent: March 22, 1994
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem, an Israeli Corp.
    Inventors: Aharon Razin, Shlomo Rottem, Pinhas F. Renbaum
  • Patent number: 5295226
    Abstract: A fuzzy computer which carries out fuzzy operations using membership functions. This fuzzy computer readily processes implications made up of an antecedent expressed by fuzzy values and a consequent expressed by singleton values. This fuzzy computer includes a fuzzy processor, fuzzy controller and a MAX circuit block composite device used in same, and in addition, it contains grade-controllable membership function circuits, grade-controllable membership function generator circuits and center of gravity determination circuits which function as a useful circuit called a defuzzifier for converting fuzzy quantities to definitive values.
    Type: Grant
    Filed: September 2, 1992
    Date of Patent: March 15, 1994
    Assignee: Research Development Corporation of Japan
    Inventor: Takeshi Yamakawa
  • Patent number: 5294884
    Abstract: A magnetometer comprising a superconducting loop including a magnetic flux detecting coil and a SQUID (Superconducting QUantum Interference Device) connected to the superconducting loop via magnetic flux. A negative inductance generating device is provided having two terminals for generating a negative inductance defined by the value of the derivative of generalized magnetic flux between the two terminals with current flowing between the terminals (d.PHI./dI) being negative. The inductance of the superconducting loop is decreased by the negative inductance generating device and input signals intensified by the negative inductance generating device are detected by the SQUID. A plurality of the superconducting loops may be provided to construct a gradiometer and a variable negative inductance generating device is provided to the respective superconducting loop to equalize and intensify the sensitivities of the detection coils.
    Type: Grant
    Filed: July 23, 1993
    Date of Patent: March 15, 1994
    Assignee: Research Development Corporation of Japan
    Inventors: Eiichi Goto, Yutaka Harada
  • Patent number: 5294286
    Abstract: The thickness of a thin film of an element semiconductor may be determined by counting the number of cycles of gaseous component introductions within a crystal growth vessel. Each cycle permits at most one monolayer of growth since the pressure in the vessel during gaseous component introduction is maintained under a saturation condition. The temperature to which a substrate in the vessel is heated is that for which epitaxial growth results.
    Type: Grant
    Filed: January 12, 1993
    Date of Patent: March 15, 1994
    Assignees: Research Development Corporation of Japan, Junichi Nishizawa, Oki Electric Industry Co., Ltd., Soubei Suzuki
    Inventors: Junichi Nishizawa, Hitoshi Abe, Soubei Suzuki
  • Patent number: 5292801
    Abstract: A method is proposed of obtaining a chemical interaction between at least one reagent trapped in sol-gel glass by doping it with the reagent, and diffusible solutes or components in an adjacent liquid or gas phase. The reagents, the solutes or the components can be any organic or inorganic compounds or materials of biological origin including enzymes. The doped sol-gel glass in various forms may be useful as analytical test, chromatographic medium, sensor, catalyst or biocatalyst, electrode or enzyme electrode, or other detection device.
    Type: Grant
    Filed: August 31, 1992
    Date of Patent: March 8, 1994
    Assignee: YISSUM, Research Development Company of the Hebrew University of Jerusalem
    Inventors: David Avnir, Michael Ottolenghi, Sergei Braun, Riyka Zusman
  • Patent number: 5288496
    Abstract: A delivery for providing growth promoters to food animals is provided and a method of promoting growth in food animals using such delivery systems is described.
    Type: Grant
    Filed: May 15, 1990
    Date of Patent: February 22, 1994
    Assignee: Stolle Research & Development Corporation
    Inventor: Danny H. Lewis
  • Patent number: 5285875
    Abstract: The shock absorber has a housing containing a damping chamber, a shock absorber piston mounted for movement in the chamber and an inertia operated damping control valve in the damping chamber for altering a damping factor of the piston movement in the chamber in response to a shock input or in response to an aceleration of the shock absorber. The damping chamber comprises a cylindrical housing and the inertia operated damping control valve comprises an orifice in the damping chamber housing, a pivotable valve member positioned to cover the orifice and a resilient member for biasing the movable valve member over the orifice. The damping chamber housing is oriented generally vertically and the resilient member is positioned between the cylindrical housing and the valve member.
    Type: Grant
    Filed: November 25, 1991
    Date of Patent: February 15, 1994
    Assignee: Nissan Research & Development, Inc.
    Inventor: Carlos H. Munoz
  • Patent number: 5286727
    Abstract: Diketopiperazine compounds designated N-methylepiamauromine, epiamauromine and cycloechinulin have been isolated from the sclerotia of the fungi Aspergillus ochraceus. The compounds are effective for controlling Coleopteran and Lepidopteran insects.
    Type: Grant
    Filed: April 27, 1992
    Date of Patent: February 15, 1994
    Assignees: The United States of America as represented by the Secretary of Agriculture, University of Iowa Research Foundation, Biotechnology Research & Development Corporation
    Inventors: Florecita S. deGuzman, Patrick F. Dowd, James B. Gloer, Donald T. Wicklow
  • Patent number: 5284867
    Abstract: The use of a compound of the formula: ##STR1## having the (3S,4S) configuration, and which is essentially free of the (3R,4R) enantiomer, wherein A--B designates a 1(2) or a 6(1) double bond, R designates --CH.sub.3 or --CH.sub.2 OH, R.sup.1 designates a hydrogen atom or a lower acyl group, and R.sup.2 designates (A) a straight-chained or branched C.sub.6-12 alkyl radical; or (B) a group --O--R.sup.3, in which R.sup.3 is a straight-chained or branched C.sub.5-9 alkyl radical or a straight-chained or branched alkyl radical substituted at the terminal carbon atom by a phenyl group in the manufacture of a medicament for reducing or preventing glutamate neurotoxicity. Some of the above compounds are novel, and their preparation is described.
    Type: Grant
    Filed: April 8, 1992
    Date of Patent: February 8, 1994
    Assignees: Yissum Research Development Company of the Hebrew University in Jerusalem, Ramot University, Authority for Applied Research and Industrial Development Ltd.
    Inventors: Yoel Kloog, Jeffrey J. Feigenbaum, Raphael Mechoulam, Mordechai Sokolovsky, Simon Benita
  • Patent number: 5283417
    Abstract: The present invention provides microprocessing and the device therefor which is characterized by radiating proessing pulse laser together with trapping laser to perform the modification and processing of particles and microcapsules.In the case of using such method for implosion, the reaction group is caused to be released by imploding the microcapsule with the reactive goup enclosed to implosion, permitting specified reaction and processing.
    Type: Grant
    Filed: December 7, 1990
    Date of Patent: February 1, 1994
    Assignee: Research Development Corporation of Japan
    Inventors: Hiroaki Misawa, Keiji Sasaki, Masanori Koshioka, Noboru Kitamura, Hiroshi Masuhara
  • Patent number: 5283371
    Abstract: A process for the production of a boronic acid of formula III, ##STR1## in which an organometallic of formula IV, ##STR2## in which formula IV, M represents a metallic moiety such as --MgX, X being a halogen or an alkali metal is treated with a trialkoxy borane of formula B(OR).sub.3, R representing an alkyl group and the product is hydrolysed.
    Type: Grant
    Filed: June 26, 1991
    Date of Patent: February 1, 1994
    Assignee: National Research Development Corporation
    Inventors: Michael Elliott, Norman F. Janes, Bhupinder P. S. Khambay
  • Patent number: 5283189
    Abstract: A .beta.-galactosidase having a high thermostability is produced by Thermus sp. FERM BP-1678, FERM BP-1679, and FERM BP-1680. The .beta.-galactosidase has an optimum temperature of 75 to 85 degrees celsius, and an optimum pH of 4.5 to 6.5 and an enzymatic activity which is not lowered substantially by 50 mM each of galactose and glucose. The .beta.-galactosidase is used to hydrolyze lactose in foods, such as milk, at a high temperature at which the putrefaction by saprophytes is difficult.
    Type: Grant
    Filed: August 9, 1991
    Date of Patent: February 1, 1994
    Assignees: Research Development Corporation of Japan, Rikagaku Kenkyusho, Morinaga Milk Industry
    Inventors: Mitsunori Takase, Kouki Horikoshi
  • Patent number: 5281830
    Abstract: There are disclosed two types of gallium nitride LED having the pn junction. An LED of gallium nitride compound semiconductor (Al.sub.x Ga.sub.1-x N, where 0.ltoreq.x<1) comprises an n-layer; a p-layer which exhibits p-type conduction upon doping with p-type impurities and irradiation with electron rays, the p-layer joining to the n-layer; a first electrode for the n-layer so as to join to the n-layer, passing through a hole formed in the p-layer which extends from the p-layer to the n-layer; and a second electrode for the p-layer which is formed in a region which is separated by a groove formed in the p-layer so as to extend from the upper surface of the p-layer to said n-layer.
    Type: Grant
    Filed: October 24, 1991
    Date of Patent: January 25, 1994
    Assignees: Toyoda Gosei Co., Ltd., Nagoya University, Research Development Corporation of Japan
    Inventors: Masahiro Kotaki, Isamu Akasaki, Hiroshi Amano
  • Patent number: 5280027
    Abstract: The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumour activity; to processes for their manufacture; and to pharmaceutical compositions containing them.The invention provides a quinazoline of the formula: ##STR1## wherein R.sup.1 includes hydrogen, amino and alkyl or alkoxy each of up to 4 carbon atoms;R.sup.2 includes hydrogen, alkyl, hydroxyalkyl and halogenoalkyl each of up to 4 carbon atoms;R.sup.3 is hydrogen or alkyl or up to 3 carbon atoms;Ar is phenylene or heterocyclene;L is a group of the formula --CO.NH--, --NH.CO--, --CO.NR.sup.4 --, --NR.sup.4.CO--, --CH.dbd.CH-- or --CO.O--, wherein R.sup.4 is alkyl of up to 4 carbon atoms; and Y is a branched alkyl group bearing substituents Y.sup.2 and Y.sup.3 the definition of each independently including hydroxy, cyano, aryl and heteroaryl, and the definition of Y.sup.
    Type: Grant
    Filed: May 30, 1991
    Date of Patent: January 18, 1994
    Assignees: Imperial Chemical Industries PLC, National Research Development Corporation
    Inventors: Robert G. Andrew, Andrew J. Barker, Francis T. Boyle, James M. Wardleworth