Patents Assigned to Research Development
  • Patent number: 5096706
    Abstract: A method of preventing, controlling or reducing adiposity in which an animal or human subject is treated with an immunogen which is a modified or unmodified antigenic substance obtainable from adipose tissue of an individual of the same species as the subject or of a species which is closely related phylogenetically to the species of the subject or which is a modified or unmodified antiidiotypic antibody or fragment thereof to an antibody raised against said antigenic substance whereby an immune response is elicited in the subject effective to prevent, control or reduce adiposity.
    Type: Grant
    Filed: March 25, 1986
    Date of Patent: March 17, 1992
    Assignee: National Research Development Corporation
    Inventor: David J. Flint
  • Patent number: 5096896
    Abstract: A non-crosslinked derivative formable by reacting at least one substituted or unsubstituted, saturated or unsaturated, mono-, di- or poly-carboxy, hydroxy or mercapto hydrocarbon with at least one cyclic unsaturated (thio)ether.
    Type: Grant
    Filed: January 10, 1989
    Date of Patent: March 17, 1992
    Assignee: National Research Development Corporation
    Inventors: Neil B. Graham, Robert E. Howells, David A. Wood, Koritala P. Rao
  • Patent number: 5097275
    Abstract: An ink jet printer head which prints by jetting out ink from a nozzle by means of a heating element. The printer head has two ink chambers above the heating element, with a partition plate separating the two ink chambers. There are at least two holes in the partition plate and allow ink to pass therethrough. At least one of the two holes and the nozzle are provided substantially coaxially with the center of the heating element.
    Type: Grant
    Filed: February 12, 1991
    Date of Patent: March 17, 1992
    Assignee: Silk Research & Development Co., Ltd.
    Inventor: Masaaki Takita
  • Patent number: 5094975
    Abstract: A thin, electrically insulating film is formed on a crystalline substrate and a multiplicity of holes are densely formed in the film. Conductive crystals are epitaxially grown on the substrate exposed in the holes, thereby forming on said substrate densely populated probes having sharp apices.
    Type: Grant
    Filed: May 16, 1989
    Date of Patent: March 10, 1992
    Assignees: Research Development Corporation, Byron Bong Siu
    Inventor: Bryon B. Siu
  • Patent number: 5092107
    Abstract: A carton (11) with parallel flat front and rear surfaces joined by curved sides and a flip-top lid (10) hinged to the carton. The carton is composed of two superimposed layers adhesively secured at a joint line at lapped edges. The outer layer is slit along its front surface parallel to the carton ends and along upwardly extending curves around the sides to a fold line parallel to and raised above the front slit and the inner layer (12) has a cutout in its front surface above the front slit of the outer layer. The cutout curves upwardly short of the sides where tags (13) are cut out of the sides of the inner layer and the outer layer overlaps the inner layer at the carton ends. Top and bottom closures are adhesively secured to the outer layer at the ends of the carton.
    Type: Grant
    Filed: June 25, 1991
    Date of Patent: March 3, 1992
    Assignee: Tobacco Research & Development Institute Limited
    Inventor: Klaus P. Lamm
  • Patent number: 5091626
    Abstract: A method for the ablative reshaping of material surfaces, including the steps of providing a source of an ablative beam having a given average fluence distribution over its cross-sectional extent, determining the ablation curve of the material to be reshaped, selecting, from said ablation curve, an ascending region having an at least approximately constant slope, selecting a beam fluence from among the fluences comprised in said region, irradiating the material surface to be shaped, and controlling the geometry of the material surface thus being reshaped by controlling the total amount of energy per unit area of said surface delivered during said irradiation.
    Type: Grant
    Filed: February 2, 1990
    Date of Patent: February 25, 1992
    Assignees: Hadassah Medical Organization, Israel Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Aaron Lewis, Amihay Fuxbruner, Itzhak Hemo
  • Patent number: 5090240
    Abstract: A bypass flowmeter assembly has a plurality of branch pipes (11) connected in parallel with a main pipe (10), with at least one of the branch pipes having a respective flowmeter (14), and at least another of the branch pipes having respective selectively operable pipe closure means (12, 13). Preferably each branch pipe has a flowmeter and closure means. Preferably also control means (30) are provided to operate the closure means through a routine of successive phases of respectively different patterns of branch pipe flow. This allows derivation of main pipe flow rate on the basis of branch pipe flowmeter measurements with comparison of flowmeter outputs between different phases to eliminate high order measurement error, averaging of such outputs to reduce low order measurement error, or by computation to eliminate unknown factors. The assembly can be connected serially with a similar assembly (20) to monitor relative variations in the total flow of interest and adjust the actual measurement of this flow.
    Type: Grant
    Filed: May 18, 1990
    Date of Patent: February 25, 1992
    Assignee: National Research Development Corp.
    Inventors: Roger C. Baker, Edward H. Higham
  • Patent number: 5091306
    Abstract: The invention provides a method for testing for the presence of catalase in a milk sample comprising combining a milk sample with a substantially catalase-free alkaline protease enzyme enriched detergent to disrupt catalase containing somatic cells present therein and release active catalase therefrom in the present of a pH buffering salt having a concentration of at least 20 mM in the resulting sample solution and providing the solution with a pH in a range of about 7.0-8.0 and thereafter testing the sample for the presence of catalase, as well as providing a test kit for detecting the presence of catalase in milk comprising a substantially catalase-free alkaline protease enzyme enriched detergent and 20 to 400 micromoles of a pH buffer alone or in combination with any other solute capable of reducing the solubility of oxygen in milk and of providing the resulting milk solution with a pH in the range of about 7.0-8.0.
    Type: Grant
    Filed: March 2, 1988
    Date of Patent: February 25, 1992
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventor: Nathan Citri
  • Patent number: 5089263
    Abstract: Microorganisms isolated from soil enriched with chitin or collagen were found to be very effective in controlling soil nematodes, probably by destroying their eggs or egg-shells. Pure culture of such microorganisms were prepared. These microorganisms are formulated into solid or liquid nematicidal compositions and as such used for combating soil-nematode infestations.
    Type: Grant
    Filed: August 4, 1989
    Date of Patent: February 18, 1992
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Itzhak Spiegel, Ilan Chet, Eli Cohn, Sergio Galper
  • Patent number: 5089499
    Abstract: The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumor activity; to processes for their manufacture; and to pharmaceutical compositions containing them. The invention provides a quinazoline of the formula: ##STR1## wherein R.sup.1 is hydrogen or amino, or alkyl or alkoxy each of up to 6 carbon atoms; or R.sup.1 is substituted alkyl or alkoxy each of up to 3 carbon atoms;R.sup.2 is hydrogen, alkyl, alkenyl, alkynyl, hydroxyalkyl, halogenoalkyl or cyanoalkyl each of up to 6 carbon atoms;Ar is phenylene or heterocyclene;L is a group of the formula --CO.NH--, --NH.CO--, --CO.NR.sup.3 --, --NR.sup.3. CO--, --CH.dbd.CH--, --CH.sub.2 O--, --OCH.sub.2, --CH.sub.2 S--, --SCH.sub.2 --, --CO.CH.sub.2 --, --CH.sub.2.CO-- or --CO.O--, wherein R.sup.3 is alkyl of up to 6 carbon atoms; andY is aryl or heteroaryl or a hydrogenated derivative thereof: orY is a group of the formula --A--Y.sup.
    Type: Grant
    Filed: December 14, 1989
    Date of Patent: February 18, 1992
    Assignees: Imperial Chemical Industries PLC, National Research Development Corporation
    Inventors: Andrew J. Barker, Leslie R. Hughes, Peter R. Marsham, John Oldfield, Stephen J. Pegg
  • Patent number: 5087451
    Abstract: Periodontal disease is treated with a composition comprising a topically-retainable carrier such as an alginate gel and a non-toxic electron acceptor, such as a ferric compound or a redox organic dye, especially methylene blue or patent blue V, which does not supply molecular oxygen.
    Type: Grant
    Filed: March 7, 1988
    Date of Patent: February 11, 1992
    Assignee: National Research Development Corporation
    Inventors: Michael Wilson, Wilson Harvey
  • Patent number: 5084926
    Abstract: A pillow is of rectangular form having front and rear rolls (17,18) at its longer sides and side rolls at its shorter sides, upper and lower surfaces (15, 16) of the pillow having respective large, central recessed areas (19, 20) between the front and rear rolls, the rolls being interrupted by minor recesses (21, 22 21a, 22a30, 31) extending from respective sides of the pillow into the central recessed areas of the upper and lower surfaces respectively, the front and rear rolls forming on each surface a central main buttress and together with the side rolls forming four corner buttresses, side buttresses also being formed between pairs of adjacent corner buttresses respectively, the side buttresses tapering in width and height away from their respective associated sides of the pillow into a central recessed area (19, 20).
    Type: Grant
    Filed: July 23, 1990
    Date of Patent: February 4, 1992
    Assignee: National Research Development Corporation
    Inventors: James A. Wattie, Joanne M. Wattie
  • Patent number: 5084776
    Abstract: Replay apparatus for replaying in a second medium a hologram recorded by recording apparatus in a first medium having a refractive index different from that of said second medium wherein said replay apparatus incorporates correcting means for correcting aberrations introduced by said recording apparatus.
    Type: Grant
    Filed: December 31, 1990
    Date of Patent: January 28, 1992
    Assignee: National Research Development Corporation
    Inventor: John Watson
  • Patent number: 5084030
    Abstract: A safety device for a hypodermic needle or for a similar instrument used in the clinical puncture of the skin comprises a sheath (6, 25 or 32) adapted to be connected to the needle (5, 21 or 33) or to a support (4 or 31) for the needle. The sheath is so connected in a first position (FIG. 1A, 2A, or 3A) which permits normal use of the needle and can be placed, by movement relative to the needle (FIG. 1B or 3B) or by folding upon itself (FIGS. 2B and 2C) in a second position in which the needle is encapsulated by the sheath. The sheath is retained in that second position, for example by a projection (9, 27 or 35) extending into a slot (10 or 36) or through an aperture (28).
    Type: Grant
    Filed: October 11, 1990
    Date of Patent: January 28, 1992
    Assignee: National Research Development Corporation
    Inventors: Phillip O. Byrne, Penelope R. Sisson, Harry R. Ingham
  • Patent number: 5081282
    Abstract: Bicyclo prostaglandin analogues have been prepared.
    Type: Grant
    Filed: January 13, 1988
    Date of Patent: January 14, 1992
    Assignee: National Research Development Corporation
    Inventors: Robert L. Jones, Norman H. Wilson
  • Patent number: 5079009
    Abstract: A controlled release composition comprising an active substance other than a prostaglandin and a polymeric carrier therefor comprising residues having a ratio of number average molecular weight to functionality greater than 1000 which comprises polyethylene oxide and are cross-linked through urethane groups.
    Type: Grant
    Filed: January 2, 1990
    Date of Patent: January 7, 1992
    Assignee: National Research Development Corporation
    Inventors: Mostyn P. Embrey, Neil B. Graham
  • Patent number: 5079493
    Abstract: An ultra-precise positioning system includes a movable part, a rolling guide, a fixed part in supporting contact with the rolling guide, and a driving device for driving the movable part. The driving device includes a non-contact motor which applies a force to the movable part without touching engagement with the movable part.
    Type: Grant
    Filed: May 31, 1990
    Date of Patent: January 7, 1992
    Assignee: Research Development Corporation of Japan
    Inventors: Shigeru Futami, Akihiro Furutani
  • Patent number: 5078754
    Abstract: The invention relates to a system and apparatus and a method for finishing and polishing a dental composite restorative material in a tooth. The system of the invention uses an elastomeric polymer disc which is impregnated with an abrasive for reducing of the composite, and a felt, suede, or elastomeric polymer foam element for polishing the composite. A method of using the above apparatus in a finishing/polishing system is also provided.
    Type: Grant
    Filed: August 1, 1988
    Date of Patent: January 7, 1992
    Assignee: Dentsply Research & Development Corp.
    Inventors: Steven R. Jefferies, Roy L. Smith, Russell D. Green
  • Patent number: RE33801
    Abstract: A combination mixing and discharge capsule for storing separate ingredients which are to be mixed together prior to use and including a container body for one ingredient closed at one end by a slidable piston and the opposite end being displaceably received in a cup-shaped cap which forms a second compartment with a perforated wall of the container body opposite the end containing the piston for receiving a frangible pillow containing a liquid second ingredient to be mixed with the ingredient in the body. The cap has a discharge nozzle extending axially therefrom and when the cap is displaced farther onto the body the innermost wall of the pillow is burst to cause the discharge of the liquid ingredient through the perforated wall end into the container body for mixing with the ingredient therein.
    Type: Grant
    Filed: August 15, 1988
    Date of Patent: January 21, 1992
    Assignee: Dentsply Research & Development Corp.
    Inventor: Russell D. Green
  • Patent number: D323699
    Type: Grant
    Filed: February 21, 1989
    Date of Patent: February 4, 1992
    Assignee: H.K. Research & Development, Inc.
    Inventor: Randy Ambrose