Patents Assigned to Research Foundation of The City University of New York
  • Publication number: 20140199297
    Abstract: In the present invention, different strategies are used to improve the bioavailability of triterpene glycosides and triterpenes including, for example, (a) a covalent approach involving modification with polyethylene glycol and (b) a formulation approach involving non-covalent encapsulation in antibody targeted pol(DL-lactic acid) nanoparticles.
    Type: Application
    Filed: January 17, 2014
    Publication date: July 17, 2014
    Applicant: Research Foundation of the City University of New York
    Inventors: Linda Saxe Einbond, Krishnaswami Raja
  • Patent number: 8776250
    Abstract: Disclosed in this specification is a method and program storage device for comparing two sets of private data without revealing those private data. If the comparison deems the two data sets sufficiently similar, helper data may be provided to permit reconstruction of one of the private data sets without transmission of that private data set.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: July 8, 2014
    Assignee: Research Foundation of the City University of New York
    Inventors: Bon K. Sy, Arun Prakash Kumara Krishnan
  • Publication number: 20140184384
    Abstract: An assistive device includes a sensor that detects information using a first modality; an actuator that conveys information using a second, different modality; and a controller that automatically receives information from the sensor and operates the actuator to provide a corresponding actuation. A sensory assisting system for a user includes assistive devices and a support the user wears to hold the devices in proximity to body parts. The fields of view of the devices' sensors extend at least partly outward from the body parts. The controller reads the sensors and operates the corresponding actuators. A method of configuring a sensory assisting system includes successively activating actuators and receiving corresponding user feedback; determining perceptibility relationships for devices per the feedback; and repeatedly: activating the actuators per a virtual environment, a user avatar position, and the relationships; receiving a user navigation command; and moving the user avatar.
    Type: Application
    Filed: December 27, 2013
    Publication date: July 3, 2014
    Applicant: Research Foundation of the City University of New York
    Inventors: Zhigang Zhu, Tony Ro, Lei Ai, Wai Khoo, Edgardo Molina, Frank Palmer
  • Patent number: 8765231
    Abstract: Disclosed in this specification is a method for aligning nanostructures. A substrate is coated with a liquid solution comprising particles. Before the solution is cured, circularly-polarized light is applied to the substrate to induce a magnetic field in the particles. A low strength magnetic field is then applied. The induced magnetic field of the particles aligns with the applied magnetic field. The solution is permitted to cure while simultaneously exposed to both the circularly-polarized light and the applied magnetic field. The resulting composite retains the particle alignment.
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: July 1, 2014
    Assignee: Research Foundation of the City University of New York
    Inventors: Luat T. Vuong, Matthew Moocarme
  • Patent number: 8748568
    Abstract: Isolated peptides are provided that are effective in inducing long-term inactivation of voltage-gated sodium channels (VGSCs) in mammalian cells. Such peptides are useful in reducing the action potentials of these excitable cells, for example, neurons, myocytes, and tonic muscle cells, in mammals in need thereof.
    Type: Grant
    Filed: May 6, 2010
    Date of Patent: June 10, 2014
    Assignee: Research Foundation of The City University of New York
    Inventors: Mitchell Goldfarb, Dover Katarzyna
  • Patent number: 8748484
    Abstract: An anti-cancer ruthenium complex containing organometallic triruthenium with two maltol ligands is claimed.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: June 10, 2014
    Assignee: Research Foundation of The City University of New York
    Inventor: Varattur Dayal Reddy
  • Patent number: 8741967
    Abstract: The present invention is directed to unsaturated sphingosine compounds which are useful as therapeutic agents for the treatment of cancer and for the treatment of other diseases including diabetes and infection with intracellular bacteria. This invention is also directed to methods of using the compounds and pharmaceutical compositions comprising the compounds in treating these diseases.
    Type: Grant
    Filed: December 12, 2008
    Date of Patent: June 3, 2014
    Assignees: Children's Hospital & Research Center at Oakland, Research Foundation of the City University of New York
    Inventors: Julie D. Saba, Henrik Fyrst, Robert Bittman
  • Patent number: 8722571
    Abstract: The invention is directed to an adsorbent comprising: a) 20-30% porous carbon with incorporated organic nitrogen species; and b) 70-80% inorganic matter. The invention is directed to a method of making an adsorbent which comprises: a) thermally drying dewatered sewage sludge to form granulated organic fertilizer; and b) pyrolyzing said the organic fertilizer at temperatures between 600 and 1000° C. The invention is additionally directed to the process of removing acidic gases from wet air streams comprising putting an adsorbent in contact with the wet air stream and allowing the adsorbent to adsorb the acidic gases.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: May 13, 2014
    Assignee: Research Foundation of the City University of New York
    Inventors: Teresa J. Bandosz, Andriy Bahryeyev, David C. Locke
  • Patent number: 8724768
    Abstract: A method of storing heat includes moving a portion of a heated fluid from at least one reactor core to at least one tank having solid media, storing heat from the portion of the heated fluid in the solid media, and transferring the stored heat from the solid media to a fluid that can be used by a power plant to generate electrical energy. A system for storing heat in a nuclear power plant includes at least one tank comprising solid media structured and arranged to store heat and an arrangement structured and arranged to pass a first fluid through the at least one tank, transfer heat from the first fluid to the solid media, store the heat in the solid media, and transfer the heat from the solid media to a second fluid. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: May 13, 2014
    Assignee: Research Foundation of the City University of New York
    Inventors: Reuel Shinnar, Robert L. Hirsch
  • Patent number: 8721937
    Abstract: This disclosure relates to a method of preparing polyamide particles. The method include spray drying a solution containing a polyamide to form polyamide particles having an average diameter of between about 0.5 ?m and about 10 ?m and at least about 85% of the polyamide particles having a diameter distribution of no more than about 1.5 ?m.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: May 13, 2014
    Assignee: Research Foundation of The City University of New York
    Inventors: Alexander Couzis, Jeffrey Morris, Ankur D. Shah, Vilobh Shete
  • Patent number: 8718778
    Abstract: There is provided method and apparatus for enhancing focality of neurocranial electrostimulation, including: providing a first plurality of electrodes having at least one electrode; providing a second plurality of electrodes having at least two electrodes; locating the first and the second plurality of electrodes on cranium of a subject and supplying electric current of opposite polarities to the first and the second plurality of electrodes. At least one electrode of the first plurality of electrodes is surrounded by at least two electrodes of the second plurality of electrodes. The enhanced focal stimulation may be used to treat ailments or augment cognitive performance. There are also provided methods for treating brain related ailments and performance augmentation.
    Type: Grant
    Filed: September 18, 2008
    Date of Patent: May 6, 2014
    Assignee: Research Foundation of the City University of New York
    Inventors: Marom Bikson, Abhishek Datta, Fortunato Battaglia, Maged Elwassif
  • Patent number: 8673594
    Abstract: This invention relates to the novel identification of arginase as an enzymatic activity which can reverse inhibition of neuronal regeneration in the central and peripheral nervous system. Assays to monitor the effects of various agents on arginase expression and thus on neuronal regeneration and repair and to identify agents which will block or promote the inhibitory effects on neuronal outgrowth are provided. This invention also relates to compositions and methods using agents that can reverse the inhibitory effects of myelin on neural regeneration by affecting arginase activity or putrescine and derivative polyamine levels in a neuron.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: March 18, 2014
    Assignees: Research Foundation of City University of New York, Beth Israel Deaconness Medical Center
    Inventors: Marie T. Filbin, Rajiv R. Ratan
  • Publication number: 20140050666
    Abstract: The present invention relates to a composition comprising a lysosomal enzyme conjugated to a negatively charged scavenger receptor ligand. In some embodiments, the lysosomal enzyme is conjugated to the scavenger receptor ligand by way of a linker. The present invention also relates to a composition comprising lysosomal enzyme encapsulated by a liposome, said liposome externally comprising a negatively charged scavenger receptor ligand. The invention further encompasses a method of treating a lysosomal storage disease with the compositions listed above. The invention further encompasses a method of treating a lysosomal storage disease with an acylated, acetylated, or aconitylated lysosomal enzyme.
    Type: Application
    Filed: August 19, 2013
    Publication date: February 20, 2014
    Applicant: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: David H. Calhoun, Lane Gilchrist
  • Patent number: 8642260
    Abstract: A signal-off-quantum-dot-based sensor for detecting the presence of a target molecule comprising: an aptamer probe having a nucleotide sequence which specifically interacts with the target molecule by sequence-dependent interaction, wherein the aptamer probe is sandwiched between (a) an oligonucleotide which is immobilized on the surface of a quantum dot (QD), and (b) a fluorophore-labeled oligonucleotide, wherein when the sensor is excited by an energy source: (i) in the absence of specific interaction between the target molecule and the aptamer probe, a baseline signal is emitted, and (ii) in the presence of specific interaction between the target molecule and the aptamer probe, a detection signal is emitted, wherein the baseline signal is greater than the detection signal, whereby the presence of the target molecule is detected.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: February 4, 2014
    Assignee: The Research Foundation of the City University of New York
    Inventors: Chun-yang Zhang, Lawrence W. Johnson
  • Publication number: 20140031565
    Abstract: An anti-cancer ruthenium complex containing organometallic triruthenium with two maltol ligands is claimed.
    Type: Application
    Filed: April 9, 2012
    Publication date: January 30, 2014
    Applicant: The Research Foundation of the City University of NEW YORK
    Inventor: Varattur Dayal Reddy
  • Patent number: 8638695
    Abstract: A routing method of a wireless communication system is provided implementing advantageous features of both the tree routing and the link state routing. In the routing method, the system generates an adaptive tree table which defines a network in a tree structure of at least one branch with at least one node and each node generates a link state table which includes information on neighbor nodes, such that the packets are routed on the basis of the adaptive tree table and the link state table. Advantageous mechanisms of the tree routing and the link state routing are combined, thereby it is possible to eliminate most single point of failures of conventional tree routing and provide shorter paths compared with conventional tree routing.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: January 28, 2014
    Assignees: Samsung Electronics Co., Ltd., The Research Foundation of the City University of New York
    Inventors: Jianliang Zheng, Myung-Jong Lee, Jin-Sae Jung
  • Patent number: 8633331
    Abstract: The present invention relates to nanocomposite materials comprising: graphite-based material dispersed among transition metal-organic framework (MOF) units, wherein the graphite-based material is chemically linked to MOF units; wherein the graphite-based material is present in the range of about 5 wt. % to about 60 wt. % of the composite material.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: January 21, 2014
    Assignee: Research Foundation of the City University of New York
    Inventors: Teresa J. Bandosz, Camille Petit
  • Publication number: 20140011763
    Abstract: The present invention relates to novel 1,2,3-triazolyl purine derivatives. The invention also relates to using the derivatives to treat cancer and various viral infections.
    Type: Application
    Filed: July 8, 2013
    Publication date: January 9, 2014
    Applicant: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventor: Mahesh K. Lakshman
  • Patent number: 8621868
    Abstract: A method for storing heat from a solar collector CSTC in Concentrating Solar Power plants and delivering the heat to the power plant PP when needed. The method uses a compressed gas such as carbon dioxide or air as a heat transfer medium in the collectors CSTC and transferring the heat by depositing it on a bed of heat-resistant solids and later, recovering the heat by a second circuit of the same compressed gas. The storage system HSS is designed to allow the heat to be recovered at a high efficiency with practically no reduction in temperature. Unlike liquid heat transfer media, our storage method itself can operate at very high temperatures, up to 3000° F., a capability which can lead to greater efficiency.
    Type: Grant
    Filed: May 13, 2011
    Date of Patent: January 7, 2014
    Assignee: Research Foundation of the City University of New York
    Inventor: Reuel Shinnar
  • Patent number: 8610103
    Abstract: A mechanically flexible array of optically pumped vertical cavity surface emitting lasers, fabricated using spin coating. The array uses InGaP colloidal quantum dots as an active medium and alternating polymer layers of different refractive indices as Bragg mirrors. Enhanced spontaneous emission is produced. The flexible array can be peeled off a substrate, producing a flexible structure that can conform to a wide variety of shapes, and having an emission spectrum that can be mechanically tuned. The flexible array can be used to create a flexible infrared light bandage.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: December 17, 2013
    Assignee: Research Foundation of the City University of New York
    Inventors: Vinod M. Menon, Nikesh V. Valappil