Patents Assigned to Research Foundation of The City University of New York
  • Publication number: 20160236146
    Abstract: Industrial waste derived adsorbents were obtained by pyrolysis of sewage sludge, metal sludge, waste oil sludge and tobacco waste in some combination. The materials were used as media to remove hydrogen sulfide at room temperature in the presence of moisture. The initial and exhausted adsorbents after the breakthrough tests were characterized using sorption of nitrogen, thermal analysis, XRD, ICP, and surface pH measurements. Mixing tobacco and sludges result in a strong synergy enhancing the catalytic properties of adsorbents. During pyrolysis new mineral phases are formed as a result of solid state reaction between the components of the sludges. High temperature of pyrolysis is beneficial for the adsorbents due to the enhanced activation of carbonaceous phase and chemical stabilization of inorganic phase. Samples obtained at low temperature are sensitive to water, which deactivates their catalytic centers.
    Type: Application
    Filed: April 27, 2016
    Publication date: August 18, 2016
    Applicant: Research Foundation of the City University of New York
    Inventor: Teresa J. Bandosz
  • Patent number: 9419289
    Abstract: Methods of using specific operational charge and discharge parameters to extend the life of alkaline batteries are disclosed. The methods can be used with any commercial primary or secondary alkaline battery, as well as with newer alkaline battery designs, including batteries with flowing electrolyte. The methods include cycling batteries within a narrow operating voltage window, with minimum and maximum cut-off voltages that are set based on battery characteristics and environmental conditions. The narrow voltage window decreases available capacity but allows the batteries to be cycled for hundreds or thousands of times.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: August 16, 2016
    Assignee: Research Foundation of the City University of New York
    Inventors: Tal Sholklapper, Joshua Gallaway, Daniel Steingart, Nilesh Ingale, Michael Nyce
  • Publication number: 20160230141
    Abstract: The present invention relates to a process for enhancing the growth and increasing the biomass of yeast cultures. The addition of ethanol during log growth phase increases the yield of yeast biomass and products purified from the biomass.
    Type: Application
    Filed: September 18, 2014
    Publication date: August 11, 2016
    Applicant: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Peter Lipke, Uthama Edupaganti
  • Patent number: 9395375
    Abstract: A method for identifying modulators of Interleukin 24 (IL-24) mediated apoptosis is disclosed. For IL-24 apoptosis to be effective, the cells should express Sigma 1 Receptor (S1R). Additionally apoptosis modulators can be identified by exposing biological cells to test compounds and monitoring for signs of endoplasmic reticulum (ER) stress protein expression; calcium mobilization; or reactive oxygen species (ROS) production.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: July 19, 2016
    Assignee: Research Foundation of the City University of New York
    Inventors: Moira Sauane, Winchie Do
  • Patent number: 9381350
    Abstract: Effective systems and methods for improving neural communication impairment of a vertebrate being and affecting motor activity of a peripheral body part including a first signal providing component configured to provide pulsed peripheral stimulation signals at the peripheral body part, a second signal providing component configured to provide a pulsed motor cortex stimulation signal to a motor cortex area, a substantially DC signal providing component configured to provide direct current spinal stimulation signal at a neural spinal junction and a controller component configured to control timing of the pulsed peripheral stimulation signals and the pulsed motor cortex stimulation signal.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: July 5, 2016
    Assignee: The Research Foundation of the City University of New York
    Inventor: Zaghloul Ahmed
  • Patent number: 9379373
    Abstract: A nickel-zinc battery includes a battery housing, a nickel oxide positive electrode supported in the battery housing, a metal substrate negative electrode supported in the battery housing, a spacer disposed between the positive and negative electrodes, an electrolyte contained within the battery housing and a means for circulating electrolyte in fluid communication with the housing for circulating the electrolyte between the positive and negative electrodes. The electrolyte contains zinc and the metal substrate is adapted for deposition of the zinc during charging of the battery. The spacer maintains the positive electrode in a spaced relationship apart from the negative electrode.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: June 28, 2016
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Sanjoy Banerjee, Yasumasa Ito, Martin Klein, Michael E. Nyce, Daniel Steingart, Robert Plivelich, Joshua Gallaway
  • Publication number: 20160177292
    Abstract: A method for screening catalytic peptides using phage display technology is disclosed. A compound is exposed to a phage library. If a peptide in the library catalyzes a reaction, a gel is formed about the phage that displays the peptide. The gel, including the first phage, is separated from un-reacted phages and released from the gel. The phage is then replicated and analyzed to determine the composition of the peptide that functioned as a catalyst.
    Type: Application
    Filed: July 3, 2013
    Publication date: June 23, 2016
    Applicant: Research Foundation of the City University of New York
    Inventors: Hiroshi Matsui, Yoshiaki Maeda, Rein Ulijn
  • Publication number: 20160160436
    Abstract: The disclosure relates to a superhydrophobic surface. Methods of fabrication are disclosed including laminating an optically transparent polymer sheet with hydrophobic nanoparticles such that the nanoparticles are partially embedded and partially exposed. The resulting assembly remains optically transparent. Additional methods include the lamination of nanoparticles to flexible fabrics and the production of molded articles using nanoparticle-treated molds.
    Type: Application
    Filed: March 20, 2014
    Publication date: June 9, 2016
    Applicant: Research Foundation of the City University of New York
    Inventors: Alan Michael Lyons, QianFeng Xu
  • Patent number: 9359259
    Abstract: A convenient and versatile method for preparing complex metal oxides is disclosed. The method uses a low temperature, environmentally friendly gel-collection method to form a single phase nanomaterial. In one embodiment, the nanomaterial consists of BaAMnBTiCOD in a controlled stoichiometry.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: June 7, 2016
    Assignee: Research Foundation of the City University of New York
    Inventors: Stephen O'Brien, Shuangyi Liu, Limin Huang
  • Patent number: 9359389
    Abstract: The invention relates to novel caged ceramide 1-phosphate (C1P), caged ceramide 1-phosphate derivatives(C1P), and the method of using them for delivering C1P intracellularly in vitro and in vivo, for research and therapeutic purposes. Therapeutic purposes include treatment of diseases associated with cell death, such as neurodegerative diseases, including Alzheimer's disease. The disclosed compositions may also be used for wound healing.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: June 7, 2016
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Robert Bittman, Antonio Gomez Munoz
  • Patent number: 9345694
    Abstract: The present invention relates to a method for enhancing arginase activity in a damaged or injured cell. In other aspects, the invention provides a method for treating a disorder that can be treated by enhancing arginase activity in a human in need thereof, the method comprising administering to the human an effective amount of a compound that enhances arginase activity. Such disorders include ischemia, hypoxia, neurodegenerative disease or condition, stroke or trauma of the nervous system. In yet another aspect, the invention provides methods for promoting regeneration of a neural cell in a human in need thereof.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: May 24, 2016
    Assignees: Cornell Research Foundation, Inc., The Research Foundation of the City University of New York
    Inventors: Rajiv R. Ratan, Marie T. Filbin
  • Patent number: 9339790
    Abstract: This disclosure relates to graphene derivatives, as well as related devices including graphene derivatives and methods of using graphene derivatives.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: May 17, 2016
    Assignees: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Michele Vittadello, Kamil Woronowicz, Manish Chhowalla, Paul G. Falkowski, John W. Harrold, Jr.
  • Patent number: 9339806
    Abstract: Industrial waste derived adsorbents were obtained by pyrolysis of sewage sludge, metal sludge, waste oil sludge and tobacco waste in some combination. The materials were used as media to remove hydrogen sulfide at room temperature in the presence of moisture. The initial and exhausted adsorbents after the breakthrough tests were characterized using sorption of nitrogen, thermal analysis, XRD, ICP, and surface pH measurements. Mixing tobacco and sludges result in a strong synergy enhancing the catalytic properties of adsorbents. During pyrolysis new mineral phases are formed as a result of solid state reaction between the components of the sludges. High temperature of pyrolysis is beneficial for the adsorbents due to the enhanced activation of carbonaceous phase and chemical stabilization of inorganic phase. Samples obtained at low temperature are sensitive to water, which deactivates their catalytic centers.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: May 17, 2016
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventor: Teresa J. Bandosz
  • Patent number: 9315531
    Abstract: Titanocene-gold compounds are provided that are useful for treating cancers.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: April 19, 2016
    Assignees: Research Foundation of the City University of New York, University of Hawaii
    Inventors: Maria Contel, Jacob Fernandez-Gallardo, Benelita T. Elie, Joe W. Ramos
  • Patent number: 9315676
    Abstract: The present invention generally relates to a method of making nanoparticles and uses thereof. In particular, the invention relates to methods of making metal nanoparticles (MNPs). The invention also relates to antimicrobial uses of the nanoparticles.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: April 19, 2016
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: George John, Praveen Kumar Vemula, Pulickel Ajayan, Ashavani Kumar
  • Patent number: 9283391
    Abstract: Improved neuromodulation control of neurological abnormalities associated with effector organs in vertebrate beings using direct current stimulation for modulating spinal cord excitability, having a peripheral-current supplying component for providing direct current peripheral nerve stimulation and a spinal-current supplying component providing direct current for spinal stimulation, and a controller managing such functions.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: March 15, 2016
    Assignee: The Research Foundation of the City University of New York
    Inventor: Zaghloul Ahmed
  • Publication number: 20160040146
    Abstract: In one embodiment, the invention provides a method of purifying recombinant alpha-galactosidase A. The method includes obtaining a lysate from cells recombinantly expressing alpha-galactosidase A grown in a cell culture medium having non-precipitating phosphate; contacting said lysate with a first chromatography media that binds ?-D-mannopyranosyl or ?-D-glucopyranosyl; eluting alpha-galactosidase A from the first chromatography media to generate a first eluate having alpha-galactosidase A, wherein said eluting includes at least one elution pause between 4 and 16 hours; contacting the first eluate with a second chromatography media that binds galactose binding proteins; and eluting alpha-galactosidase A from said second chromatography media to generate a second eluate containing said recombinant alpha-galactosidase A.
    Type: Application
    Filed: June 5, 2015
    Publication date: February 11, 2016
    Applicant: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: David H. Calhoun, Abass Abdullahi
  • Patent number: 9242010
    Abstract: Water soluble polymers having formula I: Y-(L1)n1-(C(O))n2—(R1)n3—R2 are claimed. The polymers may contain multiple water soluble, immunogenicity reducing moieties and multiple active moieties. The polymers may be linked to a protein, or a peptide having up to twelve amino acids.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: January 26, 2016
    Assignee: Research Foundation of The City University of New York
    Inventors: Krishnaswami Raja, Wei Shi, Sukanta Dolai, Saadyah Averick, William L'Amoreaux, Probal Banerjee
  • Publication number: 20150376670
    Abstract: This disclosure describes unique single stranded DNA templates having a characteristic sequence and secondary structure. The DNA templates disclosed herein are useful for making small RNA molecules through promoterless transcription by a mammalian RNA polymerase, and can serve as an effective vector for producing small RNA molecules of interest in vitro, in situ and in vivo in mammalian cells.
    Type: Application
    Filed: August 21, 2015
    Publication date: December 31, 2015
    Applicant: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Kevin Ryan, Christine I. Seidl
  • Publication number: 20150376162
    Abstract: The present invention discloses novel compounds derived from NSAIDs and pharmaceutically acceptable salts thereof. Other aspects of the invention relate to use of the NSAID derivatives in treating inflammatory diseases and pharmaceutical compositions thereof.
    Type: Application
    Filed: February 7, 2014
    Publication date: December 31, 2015
    Applicant: Research Foundation of The City University of New York
    Inventors: Khosrow Kashfi, Mitali Chattopadhyay, Ravinder Kodela