Abstract: A conjugated azopolymer and methods for making same. The azopolymer includes a plurality of monomer units containing isoindigo with R1 and R2 substituent groups, wherein R1 can be one or more C1 to 30 hydrocarbons; and R2 can be H or F. The azopolymer can have a number average molecular weight (Mn) of 4 to 20 kDa; a weight average molecular weight (Mw) of 12 to 50 kDa; and a poly dispersity index (PDI) of 2 to 3. The polymer can further have selected maximal wavelengths (?max) of 481 to 709 nm and electrochemical reduction events of ?0.4 to ?1.0 V against an Ag/AgCl reference electrode.
Type:
Application
Filed:
January 19, 2022
Publication date:
July 21, 2022
Applicant:
PURDUE RESEARCH FOUNDATION
Inventors:
Jianguo Mei, Christopher Uyeda, John Andjaba, Christopher Rybak
Abstract: Use of a composition for the prevention, amelioration and/or treatment of a condition associated with cell or tissue senescence and/or inflammation and/or autophagy, the composition comprising an active ingredient taltirelin or an analogue thereof.
Abstract: The application provides modified immune effector cells wherein the DNA (cytosine-5)-methyltransferase 3A (DNMT3A)-mediated de novo DNA methylation of the cell genome is inhibited, and STAT5 signaling pathway is activated. The application also provides related pharmaceutical compositions and the methods for generating such modified immune effector cells. The application further provides uses of such modified immune effector cells for treating diseases such as cancers, infectious diseases and autoimmune diseases.
Type:
Application
Filed:
April 8, 2020
Publication date:
July 21, 2022
Applicant:
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
Inventors:
Stephen GOTTSCHALK, Giedre KRENCIUTE, Christopher PETERSEN, Benjamin YOUNGBLOOD
Abstract: The present disclosure is directed to a microwell array comprising a plurality of wells of micro-size dimensions created on porous materials. The device can be used in various cell and tissue analytical activities, and can be formed using an etching, laminating or imprinting processes.
Type:
Application
Filed:
May 8, 2020
Publication date:
July 21, 2022
Applicant:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
Inventors:
Eric BROUZES, Jin Zhu YU, Anu Priya Bharathi RAJAN, Jingfang JU, Gabor BALAZSI
Abstract: A tactile music learning apparatus converts sound data of a user's voice corresponding to original music into first tactile data including tactile information, generates a synchronized tactile pattern by synchronizing the first tactile data with second tactile data including tactile information corresponding to sound data of the original music, and transfers the synchronized tactile pattern to a tactile reproducing apparatus to allow the tactile reproducing apparatus to reproduce the synchronized tactile pattern.
Type:
Application
Filed:
October 15, 2021
Publication date:
July 21, 2022
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: The present invention relates to anti-microbially active micro and nanoparticles, compositions comprising same, and use thereof for inhibiting bacterial growth and biofilm formation on surfaces or devices, e.g., dental surfaces or devices. The present invention further discloses methods of making such anti-microbially active micro or nanoparticles.
Type:
Application
Filed:
November 22, 2021
Publication date:
July 21, 2022
Applicants:
NOBIO Ltd., Hadasit Medical Research Services and Development Ltd.
Abstract: The present application provides methods of enhancing T cell function (e.g., expansion, persistence and/or effector functions), particularly by genetic modification of the Regnase-1, Batf, and additional genes (alone or in combination). The application also provides modified T cells manufactured using the methods provided by this invention and related pharmaceutical compositions. The application further provides methods of using the modified T cells for treating a disease (e.g., a cancer or an infectious disease).
Type:
Application
Filed:
April 23, 2020
Publication date:
July 21, 2022
Applicant:
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
Inventors:
Hongbo CHI, Jun WEI, Terrence GEIGER, Wenting ZHENG
Abstract: Disclosed herein are compositions and methods for continuous AAV-based delivery of blocking anti-TSHR antibodies to a subject having a thyroid disease. The present disclosure is based, at least in part, on the realization that blocking anti-TSHR antibodies may be delivered in a continuous manner using rAAV, e.g., rAAVS, to effectively block the stimulating effects of TSAbs or TSH on TSHR, thereby blocking or reducing the synthesis of thyroid hormone. By blocking or reducing the synthesis of thyroid hormone, the presently described methods and compositions for rAAV-based delivery of blocking anti-TSHR antibodies (e.g., may be used to treat thyroid diseases, including Graves' disease, Graves' orbitopathy, and thyroid cancer without the requirement of repeated administrations.
Type:
Application
Filed:
May 29, 2020
Publication date:
July 21, 2022
Applicant:
University Of Florida Research Foundation, Incorporated
Abstract: An energy trading system and method for performing energy trading between blockchain-based servers are disclosed. Specifically, in the energy trading method, a blockchain transaction table is divided and operated into an energy channel and a trading channel for energy prosumer power trading, and a procedure for processing a transaction is provided through servers divided into an energy prosumer blockchain server, a power trading blockchain server, and an operator blockchain server.
Type:
Application
Filed:
November 12, 2021
Publication date:
July 21, 2022
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Chang-Sic CHOI, Tai-yeon KU, Dae Geun PARK, Wan Ki PARK
Abstract: A robotic arm system includes first robotic arm, second robotic arm and main controller. The first robotic arm and the second robotic arm are configured to grab object. The main controller is configured to: determine whether first force vector of first force applied by the first robotic arm to the object is equal to second force vector of second force applied by the second robotic arm to the object; when the first force vector and the second force vector are not equal, obtain a first difference between the first force vector and the second force vector; and according to the first difference, change at least one of the first force applied by the first robotic arm to the object and the second force applied by the second robotic arm to the object so that the first force vector and the second force vector are equal.
Type:
Application
Filed:
May 25, 2021
Publication date:
July 21, 2022
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: Disclosed herein are a method and an apparatus for encoding/decoding an image. The image decoding method according to the present invention includes obtaining prediction information of a current block from a bitstream and, by performing prediction based on the prediction information, generating a prediction block of the current block. Herein, the prediction information includes split prediction information of the current block. The generating of the prediction block includes obtaining a reference sample from a neighboring block of the current block, applying an interpolation filter to the reference sample, and generating the prediction block by using the reference sample to which the interpolation filter is applied. The interpolation filter is determined based on the split prediction information of the current block.
Type:
Application
Filed:
June 8, 2020
Publication date:
July 21, 2022
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Jin Ho LEE, Jung Won KANG, Ha Hyun LEE, Sung Chang LIM, Hui Yong KIM
Abstract: A digital temperature sensor circuit is disclosed. The digital temperature sensor circuit includes a proportional to the absolute temperature (PTAT) current source, generating a PTAT current proportional to absolute temperature; a sigma-delta modulation module, including an integrator, an analog-to-digital conversion unit, and a feedback digital-to-analog conversion unit; the integrator converts the PTAT current into temperature voltage; the analog-to-digital conversion unit compares the temperature voltage with a band gap reference voltage to generate a digital modulation signal with a duty ratio proportional to the temperature; the feedback digital-to-analog conversion unit adjusts the voltage input by the analog-to-digital conversion unit and controls the charging and discharging speed of the integrator; a digital filter, quantizing the digital modulation signal into a digital signal, and outputting the digital signal.
Type:
Application
Filed:
September 11, 2017
Publication date:
July 21, 2022
Applicant:
NO.24 RESEARCH INSTITUTE OF CHINA ELECTRONICS TECHNOLOGY GROUP CORPORATION
Abstract: Disclosed herein are an image encoding/decoding method and apparatus. The image decoding method of the present disclosure may include obtaining maximum transform block size information, deriving a maximum transform block size on the basis of the maximum transform block size information, and, determining ether or not a secondary inverse transform is applied to the current block on the basis of the maximum transform block size and a horizontal size and a vertical size of a current block.
Type:
Application
Filed:
June 19, 2020
Publication date:
July 21, 2022
Applicants:
Electronics and Telecommunications Research Institute, INDUSTRY-UNIVERSITY COOPERATION FOUNDATION KOREA AEROSPACE UNIVERSITY
Inventors:
Jin Ho LEE, Jung Won KANG, Ha Hyun LEE, Sung Chang LIM, Hui Yong KIM, Jae Gon KIM, Do Hyeon PARK, Ji Hoon DO, Yong Uk YOON
Abstract: A physically unclonable function magnetic memory device includes a plurality of magnetic resistance cells disposed on a substrate and each including a pinned magnetic layer, a free magnetic layer, and a tunnel insulating layer or a non-magnetic conductive layer interposed between the pinned magnetic layer and the free magnetic layer. In an operating method of the physically unclonable magnetic memory device, an external magnetic field, decaying with time, is applied to the plurality of magnetic resistance cells to randomize a magnetization direction of the free magnetic layer of each of the plurality of magnetic resistance cells.
Type:
Application
Filed:
December 30, 2021
Publication date:
July 21, 2022
Applicant:
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION(
Abstract: The present invention relates to a method and apparatus for transceiving data. A method in which a transmitting terminal transmits data to a receiving terminal in a MIMO system according to one embodiment of the present invention comprises the following steps: generating a data field containing the data; generating a signal field containing information on the data field; generating a data frame containing the data field and the signal field; and transmitting the data frame to the receiving terminal. According to the present invention, an end of the frame being transmitted is accurately notified to the receiving terminal in a communication system in which the frame is transmitted using MIMO, thereby decoding the frame in a more efficient manner at the receiving terminal.
Type:
Application
Filed:
April 9, 2022
Publication date:
July 21, 2022
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Jae Woo PARK, Jong Ee OH, Il-Gu LEE, Sok-Kyu LEE, Min Ho CHEONG, Jee Yon CHOI, Jae Seung LEE, Yun Joo KIM
Abstract: There is provided an image encoding/decoding method and apparatus. The image encoding method of the present invention includes: determining whether or not to apply filtering to a filtering target sample; determining a filter type on the basis of the determination; and applying filtering to the filtering target sample by using the determined filter type.
Type:
Application
Filed:
April 5, 2022
Publication date:
July 21, 2022
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Jin Ho LEE, Jung Won KANG, Ha Hyun LEE, Sung Chang LIM, Hui Yong KIM
Abstract: One embodiment provides a robotic system comprising: a robot, the robot further comprising a moveable robotic arm that moves within the robot's reference space; a depth-sensing camera, the camera having a reference frame that is in substantial view of the robot's reference space; a controller, the controller further comprising a processor and a computer readable memory that comprises instructions such that, when read by the controller, the controller inputs image data from the camera and sends signals to the moveable robotic arm, the instructions further comprising the steps of: calibrating the camera to the robot by instructing the robot to engage in a number of robot poses; extracting the location of the robot poses to obtain the robot poses in the camera reference frame; and creating a transformation that transforms robot points afterwards to camera points.
Abstract: A method for detecting the binding of a chromatin-associated factor of interest to a sequence of chromatin DNA in a cell, including: contacting a permeabilized cell or nucleus with a specific binding agent that specifically recognizes the chromatin-associated factor of interest, wherein the specific binding agent is linked to a nuclease that is inactive or an activatable transposome; activating the nuclease or transposase, thereby excising the sequence of chromatin DNA bound to the chromatin-associated factor of interest; isolating the excised DNA; and determining the sequence of the excised DNA, thereby detecting binding of a chromatin-associated factor of interest to a sequence of chromatin DNA in the cell.
Type:
Application
Filed:
January 26, 2022
Publication date:
July 21, 2022
Applicant:
Fred Hutchinson Cancer Research Center
Inventors:
Steven Henikoff, Hatice Seda Kaya Okur, Terri Dawn Bryson, Peter James Skene
Abstract: A focused ultrasound device and method for dermatological treatment. The focused ultrasound device includes a focused ultrasound applicator, an automatic motion mechanism, a driver, a computer, a software operation interface. In addition, the focused ultrasound method for dermatological treatment utilizes the same focused ultrasound applicator, to achieve coaxial deep layer and shallow layer ablation treatment of the skin.
Type:
Application
Filed:
June 10, 2019
Publication date:
July 21, 2022
Applicant:
NATIONAL HEALTH RESEARCH INSTITUTES
Inventors:
GIN-SHIN CHEN, FENG-HUEI LIN, JIUN-JUNG CHEN, CHIA-CHING PAN