Abstract: The present disclosure provides uses of TRPV4 antagonists in the treatment or prevention of hydrocephalus symptoms, also known as hydrocephaly, including hydrocephalus as a result of any structural defect, any metabolic defect, any injury (direct force to the head, indirect force to the head, shock waves, pressure changes, etc.), any insult (microbial, chemical, toxins, allergic reactions or other inflammatory process, or other pathology, e.g. cancer, benign tumor, etc.). Related materials and methods are also provided herein.
Type:
Grant
Filed:
May 14, 2019
Date of Patent:
May 3, 2022
Assignee:
Indiana University Research and Technology Corporation
Abstract: The present disclosure provides for an imaging probe with a rotatable core which allows for rotating imaging assembly that is larger in diameter than the lumen in which the rotatable core resides, as well as methods to construct said probes. The imaging probes are generally elongate flexible imaging catheters for use in cardiovascular procedures. The ability to have a smaller lumen to hold the rotatable core simplifies the inclusion of other functional components to the catheter and may improve the quality of the images produced.
Type:
Grant
Filed:
February 27, 2017
Date of Patent:
May 3, 2022
Assignees:
CONAVI MEDICAL INC., SUNNYBROOK RESEARCH INSTITUTE
Inventors:
Brian Courtney, Alan Soong, Deniz Jafari
Abstract: A display stand includes a frame, an actuated rotary mechanism coupled to the frame, a counterweight coupled to the actuated rotary mechanism and movable in a vertical direction during rotation of the display about the axis of rotation, and an elevation mechanism. The actuated rotary mechanism includes a display holder that is configured to mount a display to the frame and rotate the display about an axis of rotation. The counterweight and the display are located at opposite sides of a vertical plane that passes through the axis of rotation such that a combined center of mass of the display, the display holder, and the counterweight lies on the vertical plane. The frame is coupled to the elevation mechanism, and the elevation mechanism is configured to move the frame up and down.
Type:
Grant
Filed:
December 7, 2020
Date of Patent:
May 3, 2022
Assignees:
UBTECH NORTH AMERICA RESEARCH AND DEVELOPMENT CENTER CORP, UBTECH ROBOTICS CORP LTD
Abstract: Disclosed herein, are recombinant polypeptides comprising one or more homologous amino acid repeats; and, non-immunogenic bioconjugates comprising recombinant polypeptides comprising one or more homologous amino acid repeats and one or more therapeutic agents. Also, disclosed herein are pharmaceutical compositions including the recombinant polypeptides; and methods of administering the recombinant polypeptides to patients for the treatment of cancer or infections.
Abstract: The present disclosure provides a differential reference voltage buffer, including: a buffer stage, including at least a first transistor and a second transistor; a control circuit, connected with the buffer stage and forming a negative feedback structure for generating a differential reference voltage; a current compensation circuit for compensating a resistive load current of the control circuit; and a drive stage for generating an output differential reference voltage. The differential reference voltage is generated according to an external input reference voltage and a common mode input voltage. The common mode voltage can be set separately, so that the flexibility is high. The current generated by a resistive network in the control circuit is compensated by the current compensation circuit, so that the current of a follow device in the buffer stage is not influenced by the control circuit, thereby generating a differential reference voltage with high accuracy output.
Type:
Grant
Filed:
December 13, 2018
Date of Patent:
May 3, 2022
Assignee:
NO. 24 RESEARCH INSTITUTE OF CHINA ELECTRONICS TECHNOLOGY GROUP CORPORATION
Inventors:
Yan Wang, Gangyi Hu, Tao Liu, Jian'an Wang, Daiguo Xu, Guangbing Chen, Dongbing Fu
Abstract: Processes are provided for preparing molecular sieves. The process involves preparing a synthesis mixture for the molecular sieve wherein the synthesis mixture includes a morphology modifier L selected from the group consisting of nonionic surfactants, anionic surfactants, sugars and combinations thereof.
Type:
Grant
Filed:
August 20, 2019
Date of Patent:
May 3, 2022
Assignee:
ExxonMobil Research & Engineering Company
Inventors:
Preeti Kamakoti, Scott J. Weigel, Karl G. Strohmaier, Helge Jaensch, Marc H. Anthonis, Martine Dictus, Brita Engels, Darryl D. Lacy, Sina Sartipi
Abstract: Structured light approaches utilize a laser to project features, which are then captured with a camera. By knowing the disparity between the laser emitter and the camera, the system can triangulate to find the range. Four, 185 degree field-of-view cameras provide overlapping views over nearly the whole unit sphere. The cameras are separated from each other to provide parallax. A near-infrared laser projection unit sends light out into the environment, which is reflected and viewed by the cameras. The laser projection system will create vertical lines, while the cameras will be displaced from each other horizontally. This relative shift of the lines, as viewed by different cameras, enables the lines to be triangulated in 3D space. At each point in time, a vertical stripe of the world will be triangulated. Over time, the laser line will be rotated over all yaw angles to provide full a 360 degree range.
Type:
Grant
Filed:
July 26, 2018
Date of Patent:
May 3, 2022
Assignee:
Robotic Research OpCo, LLC
Inventors:
Alberto Daniel Lacaze, Karl Nicholas Murphy, Raymond Paul Wilhelm, III
Abstract: A desulfurization catalyst includes at least: 1) a sulfur-storing metal oxide, 2) an inorganic binder, 3) a wear-resistant component, and 4) an active metal component. The sulfur-storing metal is one or more of a metal of Group IIB of the periodic table, a metal of Group VB of the periodic table, and a metal of Group VIB of the periodic table, e.g., zinc. The desulfurization catalyst has a good stability and a high desulfurization activity.
Type:
Grant
Filed:
October 31, 2017
Date of Patent:
May 3, 2022
Assignees:
CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC
Inventors:
Jun Long, Shuandi Hou, Wei Lin, Ye Song, Huiping Tian
Abstract: A visualization device for a flow field includes a chamber, a power supply, at least one pair of electrodes, and at least one flow field observation module. The flow field observation module includes a high-speed camera, a light detecting component, and a light filter component. The power supply outputs a voltage to generate a plasma, and the pair of electrodes is disposed in the chamber. The flow field observation module is disposed outside the chamber and captures an image of a fluid particle excited by the plasma toward the chamber. The light filter component is disposed between the high-speed camera and the chamber. The light detecting component obtains a light information within the chamber and sends the light information to the light filter component.
Type:
Grant
Filed:
December 2, 2019
Date of Patent:
May 3, 2022
Assignee:
Industrial Technology Research Institute
Abstract: The present invention relates to an apparatus and method for encoding and decoding an image by skip encoding. The image-encoding method by skip encoding, which performs intra-prediction, comprises: performing a filtering operation on the signal which is reconstructed prior to an encoding object signal in an encoding object image; using the filtered reconstructed signal to generate a prediction signal for the encoding object signal; setting the generated prediction signal as a reconstruction signal for the encoding object signal; and not encoding the residual signal which can be generated on the basis of the difference between the encoding object signal and the prediction signal, thereby performing skip encoding on the encoding object signal.
Type:
Grant
Filed:
January 9, 2020
Date of Patent:
May 3, 2022
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Sung Chang Lim, Ha Hyun Lee, Se Yoon Jeong, Hui Yong Kim, Suk Hee Cho, Jong Ho Kim, Jin Ho Lee, Jin Soo Choi, Jin Woong Kim, Chie Teuk Ahn, Dong Gyu Sim, Seoung Jun Oh, Gwang Hoon Park, Sea Nae Park, Chan Woong Jeon
Abstract: The present disclosure relates to a composition for preventing, alleviating or treating a neurodegenerative disease, which contains Pediococcus inopinatus as an active ingredient. The Pediococcus inopinatus strain according to the present disclosure can suppress neuroinflammation and can also alleviate the symptoms of ataxia in an animal model of Parkinson's disease and, thus, can be utilized for the prevention, alleviation and treatment of various neurodegenerative diseases including Parkinson's disease.
Type:
Application
Filed:
January 15, 2020
Publication date:
April 28, 2022
Applicant:
KOREA FOOD RESEARCH INSTITUTE
Inventors:
Hak Jong CHOI, Nam Hee KIM, Hyo Kyeong PARK
Abstract: An optimization method, an optimization system for computer programming code and an electronic device using the same are provided. The optimization method includes the following steps. Several optimizers each having several branch paths are provided. A counter is set on each of the branch paths. When the optimizers run through the branch paths, the counters set on the branch paths, where the optimizer run through, are counted. The computer programming code is compiled through the optimizers. Several count values of the counters are obtained. The count values are collected to obtain a feature vector of the computer programming code. The feature vector is inputted to a machine learning model to obtain an optimizer collection suitable for the computer programming code.
Type:
Application
Filed:
December 2, 2020
Publication date:
April 28, 2022
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventors:
Jia-Rung CHANG, Yi-Chiao SU, Tien-Yuan HSIEH, Yi-Ping YOU
Abstract: The present invention relates to an extraction apparatus, extraction method, and fluidic chip for extracting a target material. In the extraction apparatus according to the present invention, in a state in which a target material is bound to a porous film in an extraction kit, when an elution solution and a magnetic solution sequentially pass, the elution solution remaining in the porous film is pushed out by the magnetic solution due to a difference in polarity, and collected in a collection chamber. In addition, even in the collection chamber, the elution solution and the magnetic solution are maintained in a stacked state due to different polarities, and in a state in which the magnetic solution in the collection chamber is physically separated from the elution solution by magnetism of a magnetism applicator, the elution solution in the collection chamber may be recovered.
Type:
Application
Filed:
February 12, 2020
Publication date:
April 28, 2022
Applicant:
Korea University Research and Business Foundation
Inventors:
Se-Hyun SHIN, Ho-Yoon LEE, Won-Hwi NA, Chan-Hee PARK
Abstract: The invention relates to the technical field of agricultural planting, in particular to a special controlled-release microbial fertilizer for peanuts in a continuous cropping field and a preparation method thereof. The fabric comprises an outer layer, a middle layer and an inner layer. Through a three-layer structure, the controlled-release fertilizer prepared by the disclosure can realize the fertilizer efficiency period of 50-60 days, and achieves the purpose of twice releases.
Type:
Application
Filed:
July 20, 2020
Publication date:
April 28, 2022
Applicant:
BIOTECHNOLOGY RESEARCH CENTER, SHANDONG ACADEMY OF AGRICULTURAL SCIENCES
Abstract: The invention relates to the technical field of agricultural planting, in particular to a controlled-release bacterial fertilizer for peanuts and a preparation method of the special controlled-release bacterial fertilizer. The special controlled-release bacterial fertilizer is composed of an inner layer and an outer layer; after the outer layer is released completely, the inner-layer network structure gradually absorbs water and preserves moisture, and has good slow release and controlled release properties, thereby achieving the gradual release of the inner layer, high fertilizer utilization rate, exerting the efficacy of the microbial agent and facilitating the large-area promotion.
Type:
Application
Filed:
July 20, 2020
Publication date:
April 28, 2022
Applicant:
Biotechnology Research Center, Shandong Academy of Agricultural Sciences
Abstract: An image sensor package and a manufacturing method thereof are provided. The image sensor package includes a redistribution circuit structure; an image sensing chip disposed on the redistribution circuit structure and having a sensing surface, on which a sensing area and a first conductive pillar arranged in the periphery of the sensing area are disposed; a lid covering the sensing area; an encapsulant disposed on the redistribution circuit structure and encapsulating at least part of the image sensing chip and the cover; and a top tier semiconductor chip disposed above the image sensing chip and having an active surface on which a first conductor is disposed. The first conductor overlaps the image sensing chip in a direction perpendicular to the sensing surface. The first conductive pillar and the first conductor are aligned and bonded to each other to electrically connect the image sensing chip and the top tier semiconductor chip.
Type:
Application
Filed:
January 5, 2022
Publication date:
April 28, 2022
Applicant:
Industrial Technology Research Institute
Abstract: Compounds and methods are provided for the treatment of neurological or mitochondrial diseases, including epilepsy. In some embodiments, the compounds are substituted 1,4-naphthoquinones.
Type:
Application
Filed:
July 29, 2019
Publication date:
April 28, 2022
Applicant:
MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
Inventors:
James C. CHOU, Sherine S.L. CHAN, Richard A. HIMES
Abstract: A method for rapid reconstruction of a woven composite material microstructure based on topological features is provided. First, geometric modeling is performed according to the topological features of fiber bundles and matrix in a woven composite structure, then the topological features are identified on the basis of a ?-computed tomography (CT) sequence image, the change laws of the features are extracted, and finally, a geometric model is reconstructed to complete the modeling of a microstructure. Compared with the structure modeling method based on weaving process parameters, the consistency between the reconstructed model and a real woven structure is improved, facilitating the improvement of the accuracy of the subsequent calculation of the mechanical properties of the material; and compared with the method for structure reconstruction directly on the basis of a ?CT image, a tedious point cloud data process is simplified and calculation costs are greatly reduced.
Type:
Application
Filed:
June 4, 2020
Publication date:
April 28, 2022
Applicants:
SHAOXING RESEARCH INSTITUTE OF SHANGHAI UNIVERSITY, SHANGHAI UNIVERSITY
Inventors:
Aijun Li, Dan Zhang, Jingchao Yuan, Meihua Shi
Abstract: A new and distinctive cultivar of Abelia plant named ‘00-BC-47-13R’ characterized by a combination of colorful display due to golden-yellow-green and green foliage that changes from early spring through late fall, relatively short height, and the abundant blooms of white flowers with greyed-orange or red sepals from June through September.
Type:
Grant
Filed:
May 11, 2021
Date of Patent:
May 3, 2022
Assignee:
University of Georgia Research Foundation, Inc.
Inventors:
Carol Robacker, Allen Byous, Sherrod Baden