Abstract: The present invention relates to an heparanase-binding and heparanase-neutralizing monoclonal antibody (IgG-1 mAb A54), including its epitope (HBD-II) and mode of interaction with heparanase, pharmaceutical composition comprising same, and uses thereof e.g. for inhibiting or treating a disease or disorder associated with heparanase activity, including but not limited to cancer, inflammation, viral infection, diabetes and related complications. The present invention further provides combinatorial cancer therapies, comprising the heparanase-neutralizing mAb and an additional anti-cancer treatment such as chemotherapy or radiation.

Abstract: Systems and methods for determining a maximum phase recovery envelope are disclosed herein. In one example, a system includes a processor and a memory having a vehicle control module. The vehicle control module includes instructions that, when executed by the processor, cause the processor to determine a critical point on a phase plane indicating a maximum defined recovery point a vehicle can recover from, perform forward and reverse simulations from the critical point to define outermost contours of a maximum phase recovery envelope using parameters and state of the vehicle, and cause the vehicle to operate within the maximum phase recovery envelope.

Abstract: The invention provides compounds of Formula (I): as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.

Abstract: A method of treating and attenuating L-DOPA-induced dyskinesia, comprising administering an effective dose of at least one pharmacological agent, e.g., vilazodone, having serotonin-specific reuptake inhibition (SSRI) and serotonin receptor 1A (5-HT1AR) partial agonism activity, in conjunction with L-DOPA. Other agents, such as an L-DOPA decarboxylase inhibitor, e.g., carbidopa, or other adjunct treatments may also be provided.

Abstract: Disclosed are an aluminum-scandium alloy target with high scandium content and a preparation method thereof. The method comprises: preparing aluminum and scandium; melting the scandium; mixing the aluminum into the scandium, smelting and cooling to obtain an aluminum-scandium alloy through a plurality of cycles; ball-milling the alloy to obtain alloy powder and drying in vacuum, then pre-pressing and sintering in vacuum to obtain an aluminum-scandium alloy target billet; performing a thermal deformation process on the target billet to obtain the target, comprising hot forging, hot rolling and finish machining. In the present disclosure, the target has more uniform structure and chemical composition, higher relative density (up to 99.0% or more), finer grain size and higher ductility; reduce defects of shrinkage cavity and porosity, save material cost, solve problem of alloys with high brittleness, unable to process targets, meeting the requirements on wiring materials for large-scale integrated circuits.

Abstract: A fully automated chemilumiescence immunoassay analyzer, including a sample and reagent receiving device for receiving a sample and a reagent, a dispensing device for aspirating and discharging the sample and the reagent, a mixing device for mixing the sample and the reagent in a reaction vessel, an incubation and luminescence detection device for incubation and luminescence detection, a magnetic separation cleaning device for separation cleaning an analyte and impurities in the reaction vessel, a reaction vessel grasping device for transferring the reaction vessel, and a liquid path device. The fully automated chemiluminescence immunoassay analyzer has a simple structure and is convenient to operate, and also reduce the overall size such that the footprint thereof is small and the production cost is reduced, so that the analyzer is easy to achieve miniaturization, and is convenient for an operator to use.

Abstract: An emergency treatment device for algal blooms in reservoir tributaries and bays includes a hull, an automatic detection unit provided on the hull, an algae collection-separation unit, an ultrasonic algae removal unit, a micro-current electrolytic algae suppression unit, an algaecide adding unit, a power unit and a control unit. The automatic detection unit, the algae collection-separation unit, the ultrasonic algae removal unit, the micro-current electrolytic algae suppression unit, the algaecide adding unit and the power unit are connected with the control unit. The algae collection-separation unit is used for suction and ex-situ treatment of high-density algae on a surface of the water body. The ultrasonic algae removal unit, the micro-current electrolytic algae suppression unit and the algaecide adding unit are used for in-situ treatment of algae in the water body.

Abstract: An augmented reality (AR) interaction authoring system is described. The AR interaction authoring system is configured to support the real-time creation of AR applications to support AR-enhanced toys. The design of the AR interaction authoring system enables bidirectional interactions between the physical-virtual space of toys and AR. The AR interaction authoring system allows intuitive authoring of AR animations and toys actuations through programming by demonstration, while referring to the physical toy for a contextual reference. Using a visual programming interface, users can create bidirectional interactions by utilizing users' input on toys to trigger AR animations and vice versa. A plug-and-play IoT toolkit is also disclosed that includes hardware to actuate common toys. In this way, users can effortlessly integrate toys into the virtual world in an impromptu design process, without lengthy electronic prototyping.

Abstract: Provided are a system and method for controlling a workflow across domains on the basis of a hierarchical engine framework. Inventive workflow control makes it possible to configure a flexible hierarchical engine framework and provide a workflow service with low latency. Also, the system and method make it possible to control a workflow by building an engine and a data pipeline across domains.

Abstract: Methods, computer program products, and systems can include, for example: receiving a plurality of signal instances of a signal emitted by a transmitter, wherein respective signal instances of the plurality of signal instances are collected at different positions. There is also set forth herein receiving by a movable receiver moving within a first location a plurality of signal instances of a signal emitted by a transmitter, wherein signal instances defining the plurality of signal instances are collected by the moveable receiver at different respective receiver positions within the first location. There is also set forth herein discovering a direction of arrival parameter value that specifies a direction of arrival of the signal emitted by the transmitter, wherein the discovering includes using a set of signal instances from the plurality of signal instances.

Abstract: Systems and methods for replicating vehicular illumination are disclosed. According to an aspect, a system includes a detector configured to sense light emitted by a host light of a host vehicle for detecting a lighting state of the host light. The system also includes a communications system configured to communicate the detected lighting state between the host light and the remote light. Further, the system includes a remote light being located on one of the host vehicle and an operator of the host vehicle and configured to replicate the lighting state of the host light.

Abstract: A method for 3D object perception is described. The method includes extracting features from each image of a synthetic stereo pair of images. The method also includes generating a low-resolution disparity image based on the features extracted from each image of the synthetic stereo pair images. The method further includes predicting, by a trained neural network, a feature map based on the low-resolution disparity image and one of the synthetic stereo pair of images. The method also includes generating, by a perception prediction head, a perception prediction of a detected 3D object based on the feature map predicted by the trained neural network.

Abstract: A DC management method, performed by a first communication node constituting an IAB network in a communication system, may comprise: receiving, from a first IAB node that is a lower node of the first communication node, a first capability report including information of DC-related capability of the first IAB node; based on the first capability report, identifying whether the first IAB node supports a multi-TRP function; based on the first capability report, identifying whether the first IAB node supports an intra-carrier DC; and based on the identified whether the first IAB node supports the multi-TRP function and whether the first IAB node supports the intra-carrier DC, configuring a DC for the first IAB node together with a second communication node that is an upper node of the first IAB node.

Abstract: A system for controlling motion of an articulated vehicle with one or multiple trailers is described. The system is configured to infer the state of a vehicle, determine a motion path with forward motions and backward motions for the vehicle based on the state, and formulate an optimal control problem for optimizing the motion path. The optimal control problem comprises an integral tracking error function indicating integral tracking error based on motion cusps relating to the motion path. The motion cusps indicate switching between forward motion and backward motion. The motion path is optimized over a prediction horizon based on solving the optimal control problem. A control command is generated for the vehicle based on the optimized motion path and a vehicle model, and the motion of the articulated vehicle is controlled based on the control command thereby changing its state.

Abstract: Described herein are compounds having Formula I or Formula II: wherein each dashed line independently represents a saturated or unsaturated bond; R1 and R?1 are aryl or heteroaryl as defined herein; and R2 and R?2 are as defined herein. Further described is a method of inhibiting nuclear translocation of ERK1/2 in a cell, by contacting the cell with a compound having Formula I or Formula II. The compounds may also be for use in treating a disease or disorder associated with nuclear translocation of ERK1/2.

Abstract: A computer-implemented method for maintaining a spacecraft near an orbit comprises steps of detecting that a distance from the spacecraft to the orbit is greater than a spacecraft threshold and in response, linearizing dynamics of the spacecraft from a current time over a time horizon with respect to a high-fidelity reference trajectory to produce a state transition matrix (STM) for an uncontrolled motion of the spacecraft within the time horizon. The STM includes non-expanding eigenvectors with magnitudes less than or equal to one and expanding eigenvectors with magnitudes greater than one. The method further comprises determining a control action that changes an upcoming state of the spacecraft to a linear combination of the non-expanding eigenvectors of the STM and generating a control command to an actuator of the spacecraft.

Abstract: A semiconductor wafer mass metrology apparatus comprising: a measurement chamber for measuring the weight and/or the mass of a semiconductor wafer; a first temperature changing part for changing a temperature of the semiconductor wafer before the semiconductor wafer is transported into the measurement chamber; and a first temperature sensor for sensing a first temperature, wherein the first temperature is: a temperature of the first temperature changing part; or a temperature of the semiconductor wafer when the semiconductor wafer is on the first temperature changing part, or when the semiconductor wafer leaves the first temperature changing part.

Abstract: A method includes: selecting, from among a series of images, a candidate image that was captured at an image-capturing time instant corresponding to a point-cloud-generating time instant at which a point cloud was generated; generating a two-dimensional data set from the point cloud; superimposing the two-dimensional data set on the candidate image to result in a superimposed image; obtaining a derived distance inconsistency between the candidate image and the two-dimensional data set in the superimposed image; feeding the derived distance inconsistency into a conversion model to obtain a derived time difference; calculating a target time instant based on the derived time difference and the image-capturing time instant of the candidate image; and selecting, from among the series of images that have been received from the image capturing device, a target image that was captured at a time instant the closest to the target time instant.

Abstract: An intelligent air-assisted spraying device for orchards includes a traction mechanism, a spaying system, a collecting system, and a processing-controlling system. The traction mechanism is provided with a spray tank. The spaying system includes a main body connected to the spray tank and multiple spraying tubes, first ends of the spraying tube are communicated with the main body, and second ends of the spraying tubes are capable of rotating. The collecting system is configured to collect a contour and a volume of the canopy, and branch and leaf density of a fruit tree. The processing-controlling system is configured to obtain multiple spraying areas, calculate an air outlet angle of each spraying tube, and control a rotation of the second end of each spraying tube according to the air outlet angle. The device can adjust the spraying direction of each spraying tube, and the quality of pesticide application can be improved.

Abstract: A microwave heating cavity includes a metal shell, a heating sleeve, a dielectric medium, an antenna bracket, a ceramic rod and a metal wire. The metal shell is provided with a middle cavity extending through the metal shell and including a first mounting cavity, a concave air cavity and a second mounting cavity. The heating sleeve is mounted in the first mounting cavity. An accommodating cavity is arranged in the heating sleeve, in which the dielectric medium is arranged. The antenna bracket is mounted in the second mounting cavity. The ceramic rod is mounted on the antenna bracket. The ceramic rod extends into the accommodating cavity and is in contact with the dielectric medium. The metal wire is spirally wound around the ceramic rod and is configured to be connected with an external power.