Abstract: A heart valve anchor apparatus may include a body having a proximal portion and a distal portion. The body may include a first radially expandable portion at the proximal portion of the body, a second radially expandable portion at the distal portion of the body, and a root portion extending from the first radially expandable portion to the second radially expandable portion, the root portion having an outer extent. The first radially expandable portion may be configured to self-expand to an outer extent greater than the outer extent of the root portion when radially unconstrained. The second radially expandable portion may be configured to self-expand to an outer extent greater than the outer extent of the root portion when radially unconstrained. In an unstressed configuration, the body may define a longitudinal centerline that extends away from a plane tangent to the root portion.
Type:
Application
Filed:
June 16, 2020
Publication date:
October 1, 2020
Applicants:
BOSTON SCIENTIFIC SCIMED, INC., MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Inventors:
Katherine L. Baldwin, James P. Rohl, James K. Cawthra, JR., Joseph A. Dearani, Daniel Shuey, Dale Groth
Abstract: Disclosed are a heterogeneous catalyst, a production method thereof, and a method for producing a lignin-derived high-substituted aromatic monomer from a woody biomass material using the heterogeneous catalyst. The heterogeneous catalyst includes a carrier; and a Ni—Al nano-particle supported on the carrier.
Type:
Application
Filed:
March 27, 2020
Publication date:
October 1, 2020
Applicant:
Research & Business Foundation Sungkyunkwan University
Abstract: A robot gripper, including at least two gripper fingers of a grasper assembly configured to perform grasping motions via actuation of independent cable ends of a plurality of cables, and configured to move toward or away from each other to perform the grasping motion. Wherein each gripper finger is actuated by a pair of cables, a cable of the pair slides in a flexible sheath when actuated by a motor, moving the gripper finger in an opposite direction of an other cable of the pair also in a flexible sheath, providing equal motions of each cable in the pair in opposite directions. A motor assembly including the motors is mounted at a location separate from the grasper assembly with the flexible sheathing extending between the assemblies. Such that the separate assembly mounting arrangement provides an improved ratio between a gripping force of the grippers versus the robot-lifted mass of the grasper assembly.
Type:
Application
Filed:
March 27, 2019
Publication date:
October 1, 2020
Applicant:
Mitsubishi Electric Research Laboratories, Inc.
Inventors:
William Yerazunis, Parthasarathi Ainampudi, Nakul Gopalan
Abstract: The present invention relates to a method for preparing encoded hydrogel particles for high sensitive detection of a target biomolecule with high accuracy, and encoded hydrogel particles prepared thereby and, specifically, to a method for preparing encoded hydrogel particles, comprising a step of synthesizing hydrogel particles, and then binding a probe thereto, and encoded hydrogel particles prepared thereby. According to the present invention, probes can be loaded with remarkably improved high efficiency, loaded probes can be uniformly distributed, and the potential problem of biomolecule detection inhibition caused by an unreacted end can be resolved. In addition, the present invention can be applied to the diagnosis of diseases or screening of drugs through high sensitive multiplex detection of target biomolecules such as nucleic acids and proteins, and therefore, can be widely used in the field of medical diagnosis including molecular diagnosis.
Type:
Application
Filed:
December 14, 2018
Publication date:
October 1, 2020
Applicant:
Korea University Research and Business Foundation
Inventors:
Ki Wan BONG, Yoon Ho ROH, Hyun June MOON, Hyun Jee LEE, Hyeon Ung KIM, Seok Joon MUN
Abstract: The present invention relates to a catalyst for dehydration of a primary alcohol, a method of preparing the same, and a method of producing an alpha-olefin using the same. The catalyst for dehydration of a primary alcohol according to the present invention has an excellent catalyst stability while having an excellent activity with respect to dehydration, and a high turnover frequency, such that a linear alpha-olefin with high purity may be produced with a high selectivity even in a case where a relatively small amount of a cocatalyst is added as compared with a homogeneous catalyst system.
Type:
Application
Filed:
February 14, 2020
Publication date:
October 1, 2020
Applicant:
KOREA INSTITUTE OF ENERGY RESEARCH
Inventors:
Kee Young KOO, Un-ho JUNG, Young-eun KIM, Hyo Been IM, Dong Hyun CHUN, Min Hye YOUN, Heon-do JEONG, Ji-chan PARK, Geun Bae RHIM, Dong-wook LEE
Abstract: A process for producing olefins by cracking paraffins in the presence of methane. In the conventional steam cracking processes for olefin production, steam is used as a diluent in the feed mixture to the thermal cracker. In the processes provided herein, methane replaces steam as a diluent in the feed mixture to the thermal cracker. Replacing steam with methane as a diluent has a potential for cost savings in the construction and operation of a thermal cracking plant for olefin production. In addition, it leads to a much simpler cracking process compared to the conventional steam cracking technology as in the state of the art.
Abstract: This document provides methods and materials involved in using measles viruses. For example, methods and materials for identifying mammals (e.g., humans) likely to respond to standard measles virus vaccines or standard measles virus-based therapies as well as methods and materials for identifying mammals (e.g., humans) unlikely to respond to standard measles virus vaccines or standard measles virus-based therapies are provided.
Type:
Application
Filed:
June 12, 2020
Publication date:
October 1, 2020
Applicant:
Mayo Foundation for Medical Education and Research
Inventors:
Richard B. Kennedy, Gregory A. Poland, Inna G. Ovsyannikova, Iana H. Haralambieva
Abstract: A battery, comprising an anode and a cathode, the cathode comprising particles having an aspect ratio between 0.09 and 0.5. In certain embodiments, the particles are ellipsoidal. The battery may comprise an electro chemical lithium-ion battery structure. Optimal particle microstructure morphologies are identified to deliver high power or energy densities.
Type:
Application
Filed:
March 4, 2020
Publication date:
October 1, 2020
Applicant:
Purdue Research Foundation
Inventors:
Lucas Darby Robinson, Ramiro Edwin Garcia
Abstract: Methods and systems including processor configured to receive a transition indication to switch a semi-autonomous vehicle from a driving mode to another driving mode while a driver is driving the vehicle on a roadway. Wherein the driving modes include an autonomous lane keeping mode, an autonomous lane change mode and a manual mode. In response to receiving the request, use protocol data to assess a status of the vehicle's environment, a vehicle state and systems of the vehicle. Select, a set of conditions corresponding to the vehicle's state, based on one or more of the assessments. Determine, whether a switch between driving modes is initiated by the driver, by verifying if the vehicle's state satisfies the set of conditions, in order to validate if the driver actuated the vehicle into or out of a safety region.
Type:
Application
Filed:
March 27, 2019
Publication date:
October 1, 2020
Applicant:
Mitsubishi Electric Research Laboratories, Inc.
Inventors:
Uros Kalabic, Rien Quirynen, Stefano Di Cairano
Abstract: An optical tissue imaging system includes a probe for insertion into a transparent cylindrical capillary. The capillary includes an internal cylindrical channel that extends along a central axis. The capillary is inserted into tissue of a subject, and the probe may rotate and translate within the capillary. The probe may include a mirror configured to reflect light to the tissue outside of the cylindrical capillary.
Abstract: A control system for controlling a power generator of a power generation system executes a control policy to map an input-and-output sequence to a current value of the excitation voltage, submits the current value of the excitation voltage to the power generator, accepts a current value of the rotor angle caused by actuating the power generator according to the current value of the excitation voltage, and updates the input-and-output sequence with the corresponding current values of the rotor angle and the excitation voltage. The input-and-output sequence of values of the operation of the power generator includes a sequence of multiple values of the rotor angle of the power generator and a corresponding sequence of multiple values of excitation voltage to the power generator causing the values of the rotor angle. The control policy maps the input-and-output sequence to a current control input defining the current value of the excitation voltage.
Type:
Application
Filed:
March 25, 2019
Publication date:
October 1, 2020
Applicant:
Mitsubishi Electric Research Laboratories, Inc.
Abstract: An image positioning method having following steps is provided. The steps include: obtaining world coordinates of two reference points and image coordinates of two projection points corresponding to the two reference points; calculating a plurality of coordinate transformation parameters relative to transformation between any image coordinates and any world coordinates corresponding to a camera according only to the world coordinates of the two reference points, the image coordinates of the two projection points, and world coordinates of the camera; obtaining an second image having an object image corresponding to an object through the camera; and positioning world coordinates of the object according to the coordinate transformation parameters.
Type:
Application
Filed:
November 27, 2019
Publication date:
October 1, 2020
Applicant:
Industrial Technology Research Institute
Abstract: A multi-satellite system includes a first satellite and a second satellite configured to be separated in a predetermined distance between the satellites after being launched into space, and a tether including an optical fiber having first and second ends, wherein the first end is connected to the first satellite and the second end is connected to the second satellite, wherein a length of the tether is greater than the predetermined distance. In this case, the first satellite includes an optical transceiver connected to the first end of the optical fiber to provide a communications link to the second satellite, a spool containing partial winding of the tether, and a free space optical transceiver to provide a first communications link to a first distant satellite.
Type:
Application
Filed:
March 27, 2019
Publication date:
October 1, 2020
Applicant:
Mitsubishi Electric Research Laboratories, Inc.
Inventors:
Kieran Parsons, Avishai Weiss, Philip Orlik, Stefano Di Cairano
Abstract: Cell-targeted serine protease constructs are provided. Such constructs can be used in methods for targeted cell killing such as for treatment cell of proliferative diseases (e.g., cancer). In some aspects, recombinant serine proteases, such as Granzyme B polypeptides, are provided that exhibit improved stability and cell toxicity. Methods and compositions for treating lapatinib or trastuzumab-resistant cancers are also provided.
Type:
Application
Filed:
June 15, 2020
Publication date:
October 1, 2020
Applicant:
Research Development Foundation
Inventors:
Michael G. ROSENBLUM, Khalid Amanali MOHAMEDALI, Lawrence H. CHEUNG
Abstract: The present application relates to compounds of Formula I (I) or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, to compositions comprising these compounds or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, and various uses in the treatment of diseases, disorders or conditions that are treatable by inhibiting interactions with BCL6 BTB and/or by degrading BCL6, such as cancer.
Type:
Application
Filed:
December 21, 2018
Publication date:
October 1, 2020
Applicant:
Ontario Institute for Cancer Research (OICR)
Inventors:
Methvin Isaac, Anh My Chau, Ahmed Mamai
Abstract: A multi-channel receiver optical sub assembly module for a fiber Bragg grating sensor according to an embodiment of the present invention includes a housing, a connection socket, an optical bench, a thermoelectric cooler, an arrayed waveguide grating chip, a photodiode array disposed on the optical bench and including a plurality of photodiode chips connected to the optical channels of the arrayed waveguide grating chip, and a printed circuit board which is connected to the other side of the housing while passing through the other side of the housing, of which a portion of a body is disposed on the optical bench, and which is connected to the photodiode array.
Type:
Application
Filed:
January 13, 2020
Publication date:
October 1, 2020
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Hyun Jin KIM, Hyoung Jun PARK, Sung Chang KIM, Kye Eun KIM, Ji Hyoung RYU, Gi Hyeon MIN, Si Woong PARK, Dong Hoon SON, Chan Il YEO
Abstract: A processor partitions a deep neural network having a plurality of exit points and at least one partition point in a branch corresponding to each of the exit points, for distributed processing in an edge device and a cloud. The processor sets environmental variables and training variables for training, selects an action to move at least one of an exit point and a partition point from a combination of the exit point and the partition point corresponding to a current state, performs the training by accumulating experience data using a reward according to the selected action and then moves to a next state, and outputs a combination of an optimal exit point and a partition point as a result of the training.
Type:
Application
Filed:
March 25, 2020
Publication date:
October 1, 2020
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Chang Sik LEE, Sung Back HONG, Seungwoo HONG, Ho Yong RYU
Abstract: The invention provides a compound of formula (Ia) or (Ib): or a salt thereof, wherein A, B, C, D, E, F, J, K, L, M, Q, V, X, Y, W and Z have any of the values described in the specification, as well as compositions comprising a compound of formula (Ia) or (Ib) or a salt thereof, and methods of use thereof.
Type:
Application
Filed:
March 10, 2020
Publication date:
October 1, 2020
Applicant:
UNIVERSITY OF IOWA RESEARCH FOUNDATION
Inventors:
Christopher Pigge, Moustafa Tarek Ahmed Ibrahim Gabr
Abstract: An object detection system for detecting and manipulating objects on a workspace includes a three dimensional (3D) sensor configured to acquire and transmit point clouds of a scene, each point cloud including one or more objects in the workspace, manipulator configured to move or grip each of the one or more objects, a memory to store the images and a computer executable program including an object detection-localization program, a segmentation program, a gripping-moving program and a geometry reconstruction program, a processor to perform the computer executable program using the images in connection with the 3D sensor, the memory and the manipulator.
Type:
Application
Filed:
March 27, 2019
Publication date:
October 1, 2020
Applicant:
Mitsubishi Electric Research Laboratories, Inc.
Inventors:
Radu Ioan Corcodel, Diogo Rodrigues Marcal de Almeida
Abstract: A speech recognition system includes an encoder to convert an input acoustic signal into a sequence of encoder states, an alignment decoder to identify locations of encoder states in the sequence of encoder states that encode transcription outputs, a partition module to partition the sequence of encoder states into a set of partitions based on the locations of the identified encoder states, and an attention-based decoder to determine the transcription outputs for each partition of encoder states submitted to the attention-based decoder as an input. Upon receiving the acoustic signal, the system uses the encoder to produce the sequence of encoder states, partitions the sequence of encoder states into the set of partitions based on the locations of the encoder states identified by the alignment decoder, and submits the set of partitions sequentially into the attention-based decoder to produce a transcription output for each of the submitted partitions.
Type:
Application
Filed:
March 25, 2019
Publication date:
October 1, 2020
Applicant:
Mitsubishi Electric Research Laboratories, Inc.
Inventors:
Niko Moritz, Takaaki Hori, Jonathan Le Roux