Patents Assigned to Research
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Publication number: 20200181644Abstract: Compositions and methods for producing modified AAV Cap genes and combinatorial libraries of chimeric AAV vectors and virions in an AAV serotype 3 background. Selecting for modified AAV3 virions displaying cell- or tissue-specific tropisms differing from WT AAV3. Using the synthetic combinatorial AAV3 capsid libraries for introducing into a selected target host cells one or more nucleic acid molecules useful in diagnostic and/or therapeutic gene-therapy regimens.Type: ApplicationFiled: October 21, 2016Publication date: June 11, 2020Applicant: University of Florida Research Foundation, IncorporatedInventors: Sergei Zolotukhin, Damien Marsic
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Publication number: 20200178565Abstract: The present disclosure relates to novel Lactobacillus curvatus WIKIM55 isolated from kimchi, and a composition containing the same. The Lactobacillus curvatus WIKIM55 according to the present disclosure is a probiotic having activities of promoting hair growth and can be diversely applied for intestinal regulation and promotion of hair growth in humans or animals.Type: ApplicationFiled: May 30, 2018Publication date: June 11, 2020Applicant: KOREA FOOD RESEARCH INSTITUTEInventors: Hak Jong CHOI, Min Sung KWON, Seul Ki LIM, Young Joon OH, Ja Young JANG, Ji Eun LEE
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Publication number: 20200179487Abstract: The invention relates to an ELABELA polypeptide or nucleic acid for use in the treatment, alleviation or prophylaxis of pre-eclampsia in an individual. In another aspect of the invention, there is provided a method of diagnosing or detecting the susceptibility of an individual to pre-eclampsia, wherein the method comprises detecting modulation, preferably down-regulation of expression, amount or activity of ELABELA.Type: ApplicationFiled: June 28, 2017Publication date: June 11, 2020Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Bruno REVERSADE, Lena Wai Mun HO
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Publication number: 20200178878Abstract: The present invention provides a method for swallow safety monitoring and a device thereof, which can monitor eating safety in real-time. By means of the real-time records of fundamental breath sound, the feeding safety for patients or weakness persons with dysphagia can be real-timely monitored and alarmed.Type: ApplicationFiled: October 31, 2019Publication date: June 11, 2020Applicant: National Applied Research LaboratoriesInventors: HUNG-MIN SUN, TZU-I TSENG, SHU-HUI HUNG
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Publication number: 20200180295Abstract: According to one embodiment of the present invention, a method for dismantling a solar cell module for recycling comprises the steps of: providing a silicon solar cell module in which a silicon solar cell element and one side of glass are bonded together by a sealing agent and a transparent conductive material layer is coated between the side of the glass and the sealing agent; applying a high voltage between the transparent conductive material layer and the other side of the glass; and separating the glass and sealing agent by exposing the silicon solar cell module having the transparent conductive material layer discolored by application of the high voltage to a moisture environment.Type: ApplicationFiled: February 18, 2020Publication date: June 11, 2020Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATIONInventors: Donghwan KIM, Se Jin PARK, Hae-Seok LEE, Yoon Mook KANG, Hyomin PARK, Soohyun BAE, Jong Won KO
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Publication number: 20200182709Abstract: A sensor is provided that is capable of sensing a level of a parameter in an environment surrounding the sensor, wirelessly transmitting data regarding the level of the parameter to another device, and converting a wireless signal to a current and powering the sensors with the current. The sensor may measure capacitance data and transmit the data to a computer to be converted into temperature readings. The sensor may provide temperature readings from multiple locations within a container into which the sensor is placed.Type: ApplicationFiled: July 22, 2019Publication date: June 11, 2020Applicant: PURDUE RESEARCH FOUNDATIONInventors: Dimitrios Peroulis, Nithin Raghunathan, Michael Todd Hall
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Publication number: 20200182887Abstract: Type 1 diabetes (T1D) patients make antibodies to self-proteins that are potential biomarkers for early detection and risk prediction. We have identified seventeen antigens as biomarkers for early diagnosis and risk prediction of T1D, including the antigens MLH1, MTIF3, PPIL2, NUP50, TOX4, FIGN, C9orf142, ZNF280D, HES1, QRFPR, CTRC, SNX6, SYTL4, ELA2A, IGRP, PAX6, and HMGN3.Type: ApplicationFiled: February 14, 2020Publication date: June 11, 2020Applicants: Arizona Board of Regents on behalf of Arizona State University, University of Florida Research Foundation, IncorporatedInventors: Joshua LaBaer, Ji Qiu, Xiaofang Bian, Desmond A. Schatz, Clive H. Wasserfall, Mark A. Atkinson
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Publication number: 20200181035Abstract: The present disclosure generally relates to layer-wise agglomerated controlled release granular urea composition and methods of making and using the layer-wise agglomerated controlled release granular urea composition. In a particular composition, the water-soluble plant nutrient comprises urea, the binding material for the core comprises corn starch, the hydrogel for the coating layer comprises corn starch hydrogel, the core has a thickness of 2.5-3.5 mm and a closed porosity of 0.05-3%, and the coating layer has a thickness of 1.35-1.5 mm and a closed porosity of 0.1-5%.Type: ApplicationFiled: December 5, 2019Publication date: June 11, 2020Applicant: Purdue Research FoundationInventors: Rose Prabin Kingsly Ambrose, Carl R Wassgren, JR., Dhananjay Pai, Yanjie Chen
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Publication number: 20200183062Abstract: Embodiments of the disclosure provide transmitters for light detection and ranging (LiDAR). The transmitter includes a plurality of laser sources and a light modulator. Each of the laser sources includes interleaved emitting regions and gaps and is configured to provide a native laser beam in a respective incident direction. The light modulator is configured to receive the native laser beams from the plurality of laser sources in different incident directions and combine the native laser beams into a combined laser beam in a diffraction direction.Type: ApplicationFiled: December 6, 2018Publication date: June 11, 2020Applicant: DiDi Research America, LLCInventors: Youmin Wang, Yonghong Guo, Chao Wang, Yue Lu, Lingkai Kong
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Publication number: 20200181371Abstract: A thermoplastic vulcanizate is provided, including 10-50 parts by weight of a nylon plastic and 50-90 parts by weight of a cross-linked acrylic rubber polymer. The cross-linked acrylic rubber polymer is dispersed in the Nylon plastic. The cross-linked acrylic rubber polymer is formed by a modified acrylic rubber polymer having a hydrolysable silane group through crosslinking in the presence of water. In the modified acrylic rubber polymer having a hydrolysable silane group, a linkage group represented by formula (I) or formula (II) is between a backbone and the hydrolysable silane group: wherein R1 is H or —OH; R2 is H, —Z?—Si(OR?)3 or C1-C10 hydrocarbon group; R3 is H or C1-C10 hydrocarbon group; Z? is a divalent bridging group; R? is individually C1-C10 hydrocarbon group. A manufacturing method of the thermoplastic vulcanizate is also provided.Type: ApplicationFiled: December 28, 2018Publication date: June 11, 2020Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Jin-an WU, Bing-Jyun ZENG, Po-I WANG, Fu-Ming CHIEN, Fan-Jie LIN, Sheng-Lung CHANG
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Publication number: 20200181204Abstract: The present invention relates to recombinant self-assembling protein nanoparticles presenting an albumin-binding peptide at the surface. For the recombinant self-assembling protein nanoparticles according to the present invention, an albumin-binding peptide can reduce the immunogenicity of the recombinant self-assembling protein nanoparticles because the albumin-binding peptide is presented at the surface, and thus binds to an albumin protein present in vivo, and the albumin-binding peptide can also provide the cancer delivery function of the recombinant self-assembling protein nanoparticles because the albumin-binding peptide binds to albumin around cancer. Simultaneously, the binding of the albumin-binding peptide to albumin can significantly increase the in vivo residence time of the recombinant self-assembling protein nanoparticles, thus increasing the potential for use in various medical applications.Type: ApplicationFiled: October 25, 2019Publication date: June 11, 2020Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATIONInventors: Jeewon LEE, Bo Ram LEE
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Publication number: 20200183493Abstract: A measurement system and a measurement method using the same are provided. Firstly, a measurement system is provided. The measurement system comprises a film, a sensor and a movement information calculator, wherein the film has a patterned structure layer, and the sensor is electrically isolated from and selectively in contact with the film. Then, the sensor directly contacts the patterned structure layer and generates a sensing signal during relative movement process between the sensor and the film. Then, the movement information calculator obtains at least one of a relative movement amount and a relative movement speed during the relative movement process according to the sensing signal.Type: ApplicationFiled: December 27, 2018Publication date: June 11, 2020Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventor: Hsuan-Yu LIN
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Publication number: 20200184720Abstract: A machining parameter automatic generation system includes a geometric data capturing module, a feature recognition learning network and a machining parameter learning network. The geometric data capturing module captures a geometric shape of a workpiece to generate a candidate feature list. The feature recognition learning network trains the candidate feature list according to a first neural network model to obtain an applicable feature list. The machining parameter learning network trains the applicable feature list and the candidate machining parameter according to a second neural network model to obtain an applicable machining parameter. The applicable machining parameter is used to generate a machining program, and the machining program is read by a machine tool for processing.Type: ApplicationFiled: December 19, 2018Publication date: June 11, 2020Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Yang-Lun LIU, Yu-Lin TSAI, Yao-Yang TSAI, Cheng-Chieh WU, Shuo-Peng LIANG
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Publication number: 20200178840Abstract: A method for marking adventitious sounds is provided. The method includes: receiving a lung sound signal generated by a sensor from a chest cavity sound signal; capturing a lung sound signal segment from the lung sound signal every sampling time interval; converting the lung sound signal segments into spectrograms; inputting the spectrograms into a recognition model to determine whether the spectrograms include adventitious sounds; obtaining time points of occurrence corresponding to the adventitious sounds according to abnormal spectrograms including the adventitious sounds, and the number of occurrences of the adventitious sounds corresponding to the time points; and marking an adventitious sound signal segment having the highest probability of occurrence of the adventitious sound in the lung sound signal according to the time points and the number of occurrences.Type: ApplicationFiled: December 28, 2018Publication date: June 11, 2020Applicant: Industrial Technology Research InstituteInventors: Chun-Fu YEH, Yi-Fei LUO, Cheng-Li CHANG, I-Ju YEH
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Publication number: 20200181234Abstract: Isolated polypeptides of CD44 are provided. Accordingly, there is provided an isolated polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. Also provided is an isolated end-capping modified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1-3, wherein the modified polypeptide comprises an anti-inflammatory activity. Also provided are compositions of matter, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease.Type: ApplicationFiled: February 18, 2020Publication date: June 11, 2020Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: David NAOR, Lora ESHKAR-SEBBAN, Keren-Or AMAR, Shmuel COHEN
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Publication number: 20200181569Abstract: The present invention relates to a method of producing expandable cultured brain cells. The brain cells are neurotrophic factor (NTF) positive. The expandable cultured brain cells are obtained by culturing a biopsy obtained from the cortical and/or subcortical brain region of a living subject. The biopsies can be obtained during neurosurgical procedures such as deep brain stimulation. The expandable cultured brain cells of the present invention are useful for the treatment of neurological diseases and other medical conditions.Type: ApplicationFiled: February 11, 2020Publication date: June 11, 2020Applicant: LONDON HEALTH SCIENCES CENTRE RESEARCH INC.Inventor: Matthew Olding HEBB
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Publication number: 20200184795Abstract: Provided is a method of controlling an intelligent river inundation alarming system, the method including acquiring river image information from at least one image acquisition device, extracting an analysis target image from the acquired river image information, performing image analysis engine learning on the basis of the extracted analysis target image, analyzing real-time river image information acquired from the image acquisition device using the learned image analysis engine, and determining whether a river is inundated on the basis of a result of the analysis of the real-time river image information.Type: ApplicationFiled: December 5, 2019Publication date: June 11, 2020Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Seung Wan HAN, Seon Ho OH
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Publication number: 20200186622Abstract: Provided are a system and method for providing a microservice-based device control interface. The system for providing a microservice-based device control interface includes a Docker registry server in which resources required for providing a device control interface are located and a gateway which receives and installs resources and provides a device control interface using a Docker-based microservice structure.Type: ApplicationFiled: December 9, 2019Publication date: June 11, 2020Applicant: Electronics and Telecommunications Research InstituteInventors: Geun Yong KIM, Byung Hee SON, Gi Ha YOON, Ryang Soo KIM, Jae In KIM, Chor Won KIM, Hee Do KIM, Hark YOO
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Publication number: 20200179686Abstract: Provided is a respiratory muscle strengthening device, in which an inhalation start signal is generated correspondingly at an inhalation start time when a patient inhales air or an exhalation start signal is generated correspondingly at an exhalation start time when the patient exhales air, an electric signal according to the inhalation start signal or the exhalation start signal is transmitted to an electric muscle stimulator via a communication unit, a muscle pad installed on respiratory muscles of the patient enables smooth breathing motion by stimulating the respiratory muscles based on a signal transmitted from the electric muscle stimulator, and a receptor pad is provided to the respiratory muscles such that an alarm of determining whether electric stimulation is normally applied via the state of the respiratory muscles detected through the receptor pad is output, thereby securing reliability of a device.Type: ApplicationFiled: June 20, 2017Publication date: June 11, 2020Applicant: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITYInventors: Su Min SON, Eun Yong CHOI, Joon Ha LEE, So Young KWAK
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Publication number: 20200181466Abstract: A resin is provided, wherein the resin is formed by reacting 1 part by mole of a multi-isocyanate core with 3 to 4.5 parts by mole of diol to form an intermediate, and then reacting the intermediate with 3 to 4.5 parts by mole of first diisocyanate. The multi-isocyanate core can be a multi-isocyanate compound with more than two isocyanate groups. Alternatively, the multi-isocyanate core can be formed by reacting a second diisocyanate with a multi-hydroxy compound, and the multi-hydroxy compound has more than two hydroxy groups.Type: ApplicationFiled: December 24, 2018Publication date: June 11, 2020Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Chao-Chieh CHIANG, Yi-Che SU, De-Lun KUO