Abstract: Discloses are a data clustering apparatus and method based on a range query using a CF tree. The data clustering apparatus includes a CF tree construction unit configured to construct a CF tree, including a leaf node configured with a micro cluster (MC) and an index node configured with a sub-cluster (SC), based on a plurality of data included in a data set, a micro cluster segment (MCS) generation unit configured to generate an MCS based on a distance between the MCs while sequentially searching the leaf node to a right, and a cluster set generation unit configured to generate a cluster set by performing a range query on the MCS.

Abstract: An object includes an electro-optic display device provided with an optically active element having optical properties that can be modified by applying an electric voltage. The object further includes a frame which delimits an opening wherein the electro-optic display device is arranged. The object also includes an external electronic power and control device and elements for the electrical connection of the electro-optic display device to the external electronic power and control device, which are hidden by the frame of the object. The electro-optic display device defines an opaque active display area having a surface area that is less than the surface area of the opening, such that, even when the electro-optic display device is activated and displaying information, a transparent area remains between the active display area and the edges of the frame, whereas an area located beneath the active display area is hidden.

Abstract: The present invention provides methods for detecting and/or treating a subject having an aneurysm or at risk for developing an aneurysm. It has been discovered that a key metabolite of the kynurenine (Kyn) pathway, a major route for the metabolism of essential amino acid tryptophan (Trp) into nicotinamide adenine dinucleotide (NAD+), plays a critical role in the formation of aneurysms, for example abdominal aortic aneurysms. In particular, it has been discovered that 3-Hydroxyanthranilic acid (3-HAA), a product of kynureninase (KYNU), plays a causative role in the formation of aneurysms by, for example exerting pro-inflammatory effects on vascular smooth muscle cells. It has further been discovered that elevated levels of 3-HAA are indicative of the presence and/or progression of an aneurysm, and 3-HAA levels correlate with the size (aortic diameter) of the aneurysm.

Abstract: An object includes an electro-optic display device provided with an optically active element, the optical properties thereof can be modified by applying an electric voltage or current between at least one electrode and one corresponding auxiliary electrode, between which the optically active element is disposed. The object further includes a middle part which delimits an opening closed by a crystal including a bottom surface beneath which the electro-optic display device is arranged. The crystal is provided with an opaque frame which is made remotely from the edges of the opening and which covers the contour of the electro-optic display device so as to conceal electrical connection elements. The electro-optic display device defines an active display area which is confined by the opaque frame, such that, when the electro-optic display device is activated and displaying information, a transparent area remains between the opaque frame and the edges of the opening.

Abstract: Systems and techniques for determining and correcting inter-wafer misalignments in a stack of wafers transported by a wafer handling robot are discussed. An enhanced automatic wafer centering system is provided that may be used to determine a smallest circle associated with the stack of wafers, which may then be used to determine whether or not the stack of wafer meets various process requirements and/or if a centering correction can be made to better align the wafers with a receiving station coordinate frame.

Abstract: A reactor cooling and power generation system according to the present disclosure may include a reactor vessel, a heat exchange section formed to receive heat generated from a core inside the reactor vessel through a fluid, and an electric power production section including a Sterling engine formed to produce electric energy using the energy of the fluid whose temperature has increased while receiving the heat of the reactor, wherein the system is formed to circulate the fluid that has received heat from the core in the heat exchange section through the electric power production section, and operate even during a normal operation and during an accident of the nuclear power plant to produce electric power. Furthermore, the reactor cooling and power generation system according to the present disclosure may be continuously operated not only during a normal operation but also during an accident to perform reactor cooling, and produce emergency power, thereby improving the system reliability.

Abstract: A biodegradable sealant includes: a polyethylene glycol derivative; a photoinitiator; and a solvent, wherein the content of the polyethylene glycol derivative is about 10-75 wt % in the biodegradable sealant. The polyethylene glycol derivative is obtained by a substitution reaction, and in the substitution reaction, the polyethylene glycol is modified with methacrylic anhydride.

Abstract: Doped titanium niobate is provided, which has a chemical structure of Ti(1-x)M1xNb(2-y)M2yO(7-z)Qz or Ti(2-x?)M1x?Nb(10-y?)M2y?O(29-z?)Qz?, wherein M1 is Li, Mg, or a combination thereof; M2 is Fe, Mn, V, Ni, Cr, or a combination thereof; Q is F, Cl, Br, I, S, or a combination thereof; 0?x?0.15; 0?y?0.15; 0.01?z?2; 0?x??0.3; 0?y??0.9; and 0.01?z??8.

Abstract: An embodiment of the present invention provides a neural network operator that performs a plurality of processes for each of a plurality of layers of a neural network, including: a memory that includes a data-storing space storing a plurality of data for performing the plurality of processes and a synapse code-storing space storing a plurality of descriptors with respect to the plurality of processes; a memory-transmitting processor that obtains the plurality of descriptors and transmits the plurality of data to the neural network operator based on the plurality of descriptors; an embedded instruction processor that obtains the plurality of descriptors from the memory-transmitting processor, transmits a first data set in a first descriptor to the neural network operator based on the first descriptor corresponding to the first process among the plurality of processes, reads a second descriptor corresponding to a second process, which is a next operation of the first process, based on the first descriptor, and

Abstract: This invention is directed to an aromatic material based free-standing film, a hybrid of organic crystalline materials and inorganic carbon nanomaterials, process of preparation and uses thereof. The film, which comprises a fibrous organic nanocrystals of an aromatic material, is mechanically and thermally stable. This film is optionally reinforced by hybridization with a reinforcement material, such as carbon nanotube, carbon material, a polysaccharide, a nanoclay a metal, metal alloy, or an organic polymer. The hybrid film of organic nanocrystals and carbon nanotubes (ONC/CNT) has high conductivity and high thermal stability. The films or hybrids of this invention are used as microfiltration membranes for various materials, in electrodes or perovskite solar cells.

Abstract: The present specification discloses a pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a disease, disorder, condition or injury of the CNS. The pharmaceutical composition is administered by a dosage regimen comprising at least one course of therapy, each course of therapy comprising in sequence a treatment session followed by an interval session of non-treatment.

Abstract: Aspects of the present invention disclose compounds that modulate the aggregation of amyloidogenic proteins or peptides. In some aspects, disclosed compounds modulate the aggregation of disease-associated proteins and natural ?-amyloid peptides. In a preferred embodiment, the compounds can inhibit natural amyloid aggregation. Pharmaceutical compositions comprising the compounds of the embodiments, and diagnostic and treatment methods for diseases (e.g., amyloidogenic diseases) using the compounds, are also disclosed. In addition, there is provided an integrated bacterial platform for the discovery of rescuers of disease-associated protein misfolding.

Abstract: The present invention relates to a technology for treating radioactive liquid waste containing a hardly degradable compound, and more specifically, to a technology for treating radioactive liquid waste containing a material such as an organic decontamination agent, an inorganic decontamination agent, liquid scintillation counter liquid waste, and the like generated at nuclear power plants, nuclear facilities, facilities at which radiation (radioactivity) is used, and the like. The method for treating radioactive liquid waste of the present invention includes adding two or more selected from the group consisting of a metal ion, an oxidizing agent, air, oxygen, or nitrous oxide, and a semiconductor to radioactive liquid waste to prepare a pre-treatment solution, and irradiating the pre-treatment solution with radiation.

Abstract: The present disclosure provides a biosignature that distinguishes Lyme disease, including early Lyme disease, from STARI. The present disclosure also provides methods for detecting Lyme disease and STARI, as well as methods for treating subjects diagnosed with Lyme disease or STARI.

Abstract: Disclosed are AAV viral-based vector compositions useful in delivering a variety of nucleic segments, including those encoding therapeutic polypetides to selected mammalian host cells for use in therapeutic autoimmune modalities, including, for example, the in vivo induction of immunological tolerance via a liver-directed AAV-based gene therapeutic regimen for treating and/or ameliorating autoimmune disorders such as multiple sclerosis.

Abstract: Disclosed herein are a gateway-signaling method for frequency/timing offsets and an apparatus for the same. An apparatus for transmitting a broadcast signal according to an embodiment of the present invention includes a frequency/timing decision unit for determining a center frequency to which a frequency offset is applied using a carrier offset, which is identified using a timing and a management packet transmitted through a Studio-to-Transmitter Link (STL); and an RF signal generation unit for generating an RF signal to be transmitted, which corresponds to the center frequency.

Abstract: A metal organic framework and a method for preparing the same, and an adsorption device employing the metal organic framework are provided. The metal organic framework includes a 3,5-pyridinedicarboxylic acid and a metal ion, which is an aluminum ion, a chromium ion, or a zirconium ion, wherein the 3,5-pyridinedicarboxylic acid is coordinated to the metal ion.

Abstract: Disclosed are a deep body spread microwave hyperthermia device for personal uses and an operation method thereof. The operating method may include generating a control signal to control patches attached to the skin of a user, dividing the control signal into a first signal and a second signal having a phase different from a phase of the first signal, transmitting the first signal and the second signal to patches attached to different positions, among the patches, and producing hyperthermia in a body of the user by radiating radio waves based on the first signal or the second signal received by each of the patches.

Abstract: The present specification discloses a pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a disease, disorder, condition or injury of the CNS. The pharmaceutical composition is administered by a dosage regimen comprising at least one course of therapy, each course of therapy comprising in sequence a treatment session followed by an interval session of non-treatment.

Abstract: The present invention relates to anovel quinolinone derivative compound that regulates intracellular signal transduction mediated by TSLP and IL-33 to exhibit efficacy in preventing or treating allergic diseases such as asthma or atopic dermatitis. The quinolinone derivative compound of the present invention can effectively suppress inflammatory responses of allergic diseases such as asthma or atopic dermatitis. The present invention also relates to a pharmaceutical composition including the quinolinone derivative compound. The pharmaceutical composition of the present invention can be used to fundamentally prevent or treat various allergic and asthmatic diseases.