Patents Assigned to Research
  • Publication number: 20190338018
    Abstract: This disclosure provides antibody fragments and isolated polypeptides comprising the antibody fragments that are useful as a therapeutic for those with an existing infection characterized by the formation of biofilms. Antibody fragments and isolated polypeptides comprising the antibody fragments can be administered to detect, treat, or prevent infection and/or remediate biofilms. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics.
    Type: Application
    Filed: January 3, 2018
    Publication date: November 7, 2019
    Applicant: Research Institute at Nationwide Children's Hospital
    Inventors: Lauren O. Bakaletz, Steven D. Goodman
  • Patent number: 10463656
    Abstract: Methods for preventing feedlot bovine respiratory diseases employing an anti-inflammatory drug rupatadine are disclosed. Compositions are further disclosed. Beneficially, the methods and compositions provide safe and cost-effective management of a costly disease.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: November 5, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Steven Alan Carlson, Timothy L. Day
  • Patent number: 10466327
    Abstract: In some aspects, a method of operating a magnetic resonance imaging system comprising a B0 magnet and at least one thermal management component configured to transfer heat away from the B0 magnet during operation is provided. The method comprises providing operating power to the B0 magnet, monitoring a temperature of the B0 magnet to determine a current temperature of the B0 magnet, and operating the at least one thermal management component at less than operational capacity in response to an occurrence of at least one event.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: November 5, 2019
    Assignee: Hyperfine Research, Inc.
    Inventors: Jonathan M. Rothberg, Jeremy Christopher Jordan, Michael Stephen Poole, Laura Sacolick, Todd Rearick, Gregory L. Charvat
  • Patent number: 10463719
    Abstract: Microorganisms comprising a maltose-inducible promoter and methods of use in producing biologics and introducing biologics to sites in a maltose-dependent manner. The microorganisms include a maltose-inducible promoter operably connected to a coding sequence of a biologic. The biologic may be a polypeptide or a nucleic acid. Polypeptide biologics may include lytic proteins and/or secreted proteins. Nucleic acid biologics may include antisense RNA, other types of RNA, or other types of nucleic acids. The microorganisms can be used to produce the biologics and/or introduce the biologics to in vitro or in vivo sites in a maltose-dependent manner. The microorganisms can also be used in maltose-dependent gene silencing.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: November 5, 2019
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Jan Peter Van Pijkeren, Jee-Hwan Oh
  • Patent number: 10466166
    Abstract: According to one aspect of the invention, there is provided an ellipsometry system for measuring any one or more of molecular binding, adsorption and desorption on a substrate, the system comprising: a) a cuvette comprising i) a body within which a cavity is formed and an opening on the body, wherein the cavity extends into the opening through which the substrate is immersed; ii) a window formed on each of two oppositely located walls of the body, wherein the windows are aligned to allow light to enter through one of the two windows to reflect off the portion of the substrate immersed in the cavity and exit through the other of the two windows; iii) a channel arrangement enclosed within the body of the cuvette and comprising two non-contiguous portions, wherein one of the two non-contiguous portions guides fluid into the cavity and the other non-contiguous portion guides fluid out of the cavity; b) a polarized light source disposed to provide the light that enters into one of the two windows on the body of th
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: November 5, 2019
    Assignee: Agency for Science, Technology and Research
    Inventors: Nikolai Yakovlev, Laura Sutarlie, Dave Siak-wei Ow, Tandiono Tandiono
  • Patent number: 10469183
    Abstract: An antenna device and a method for calibrating an antenna device are provided, and the method includes: transmitting or receiving a signal by a first antenna unit and a second antenna unit; receiving the signal from the first antenna unit and the second antenna unit or transmitting the signal to the first antenna unit and the second antenna unit by a probe, wherein the first antenna unit and the second antenna unit are at a first distance from the probe respectively; and calibrating the first antenna unit and the second antenna unit according to a beat frequency of the signal corresponding to the first distance.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: November 5, 2019
    Assignee: Industrial Technology Research Institute
    Inventors: Fang-Yao Kuo, Che-Yang Chiang, Wen-Chiang Chen
  • Patent number: 10467500
    Abstract: Methods and systems involving convolutional neural networks as applicable for semantic segmentation, including multi-task convolutional networks employing curriculum based transfer learning, are disclosed herein. In one example embodiment, a method of semantic segmentation involving a convolutional neural network includes training and applying the convolutional neural network. The training of the convolutional neural network includes each of training a semantic segmentation decoder network of the convolutional neural network, generating first feature maps by way of an encoder network of the convolutional neural network, based at least in part upon a dataset received at the encoder network, and training an instance segmentation decoder network of the convolutional neural network based at least in part upon the first feature maps.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: November 5, 2019
    Assignee: DiDi Research America, LLC
    Inventors: Ruxiao Bao, Xun Xu
  • Patent number: 10467255
    Abstract: Methods for analyzing reading log and documents corresponding thereof are provided, including: acquiring reading log and documents corresponding thereto, wherein the reading log at least includes reading-related information about the documents within a predetermined period of time, selecting interesting document sets from the documents according to the reading log in each time segment, performing a document content pre-processing on the interesting document sets to determine keyword sets corresponding thereto for each time segment according to the interesting document sets, performing cluster calculation on the keyword sets to obtain topics and calculating cohesion of each topic, deleting topics with insufficient cohesion to obtain multiple high-relevance topics and classifying each high-relevance topic into one of predetermined topic classes according to the respective keyword sets of the high-relevance topics, obtaining reading statistics for each topic class and calculating multiple degrees of interest for
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: November 5, 2019
    Assignee: Industrial Technology Research Institute
    Inventors: Tsung-Lin Tsai, Meng-Yu Lee, Shun-Chieh Lin
  • Patent number: 10463722
    Abstract: The present disclosure provides compositions comprising mutant fungi include an inactive form of the sterylglucosidase enzyme. The present disclosure is also directed to vaccine based compositions, which include a mutant fungus that prohibit pathogenic fungal infection. This disclosure also provides methods for administering these compositions as a prophylaxis against fungal infection, as well as methods for isolating sterylglucosides that include the use of such mutant fungal compositions.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: November 5, 2019
    Assignee: The Research Foundation for The State University of New York
    Inventors: Maurizio Del Poeta, Antonella Rella
  • Patent number: 10468326
    Abstract: Metamaterial systems capable of exhibiting changes in thermal conductivities in response to an external control or input, as well as methods relating thereto. The metamaterial systems include first and second plates, and a metamaterial core between and thermally coupled to the first and second plates. The metamaterial core comprises a plurality of elements coupled to and contacting each other, with each of the elements being a pseudo-tetrahedron having surfaces that define surface-to-surface contacts with at least one other of the elements. A force is applied to the metamaterial core that increases contact pressures between the elements at the surface-to-surface contacts thereof and thereby increases thermal contact conductivities at the surface-to-surface contacts and increases a thermal conductivity of the metamaterial core.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: November 5, 2019
    Assignee: Purdue Research Foundation
    Inventors: Thomas Siegmund, Yuezhong Feng, Somesh Khandelwal
  • Patent number: 10469789
    Abstract: A digital device and a control method thereof are disclosed in the present specification. The digital device and the control method thereof according to the present invention may comprise the steps of receiving an image signal; separating the received image signal by a plurality of frequency bands; adjusting a gain for the image signal of each of the separated frequency bands; displaying an enhanced image on a screen by synthesizing the image signals of the respective frequency bands in which the gain has been adjusted; separating the screen, on which the enhanced image is displayed, into a plurality of areas; checking whether the maximum pixel value of the enhanced image displayed on the separated screen area, if the maximum pixel value of the enhanced image is larger than the reference value.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: November 5, 2019
    Assignees: LG ELECTRONICS INC., INHA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Hunbae Woo, Cheoljoo Lee, Byungcheol Song, Yeonoh Nam, Dongyoon Choi
  • Patent number: 10464815
    Abstract: A thermochemical energy storage system and method of storing thermal energy are disclosed. The energy storing system described herein comprises a reactor comprising a CO2 sorbent comprising i) CaO and mayenite or ii) Li4SiO4, or a combination thereof, and b) a CO2 source, wherein the CO2 source is in fluid communication with the reactor to allow flow of CO2 between the CO2 source and the reactor. Further, methods are disclosed for storing thermal energy through a wide temperature range.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: November 5, 2019
    Assignee: Southern Research Institute
    Inventors: Ryan Melsert, Santosh Kumar Gangwal, Tim A. Hansen
  • Patent number: 10468668
    Abstract: Disclosed herein are compositions and methods of making such compositions, for making lithium-containing anodes and cathodes. Disclosed are batteries comprising such anodes and/or cathodes, and uses for such batteries. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: November 5, 2019
    Assignees: Binergy Scientific, Inc., Georgia Tech Research Corporation
    Inventors: Vojtech Svoboda, Gleb Yushin
  • Patent number: 10467125
    Abstract: Provided is a method of verifying satellite software using a simulator, the method including receiving memory data of the simulator from the simulator in a first communication mode, the simulator being loaded with the satellite software to be verified; generating a first telemetry frame from the memory data based on a telemetry frame generation rule; and analyzing the first telemetry frame.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: November 5, 2019
    Assignee: KOREA AEROSPACE RESEARCH INSTITUTE
    Inventor: Hyun-Kyu Shin
  • Patent number: 10467106
    Abstract: A data processing method, a data processing system and a computer program product are provided. The data processing method includes executing a running operation. The data processing method also includes suspending the running operation at a preset time point in a period of the running operation and calculating a remaining processing time according to a transfer amount of a plurality of dirty pages which are collected before the preset time point in the period of the running operation. The data processing method further includes continuing to execute the running operation, suspending the running operation, and executing a snapshot operation to generate a corresponding data snapshot based on the remaining processing time, and executing a transfer operation to transfer the corresponding data snapshot.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: November 5, 2019
    Assignee: Industrial Technology Research Institute
    Inventors: Po-Jui Tsao, Yi-Feng Sun, Chuan-Yu Cho, Tzi-Cker Chiueh
  • Patent number: 10466243
    Abstract: The subject invention pertains to devices and methods of isolating target cells from a population of cells. The devices comprise of microfluidic channels and aptamers and antibodies attached to the inner surface of the microfluidic channels, wherein the aptamers and the antibodies are capable of specific binding to one or more biomolecules present on the surface of the target cell. The methods of the current invention comprise passing the population of cells through the microfluidic channels to facilitate interaction and capture of the target cells by the aptamers and the antibodies attached to the inner surface of the microfluidic channels, washing to microfluidic channels by a washing solution to remove the cells non-specifically bound to the aptamers and the antibodies attached to the inner surface of the microfluidic channels, releasing the captured target cells from the microfluidic channels, and collecting the released target cells.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: November 5, 2019
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
    Inventors: Zhonghui Hugh Fan, Jinling Zhang
  • Patent number: 10463646
    Abstract: The present invention relates to micellar nanocomplexes and a method of forming the same. The micellar nanocomplex comprises a micelle and an agent encapsulated within said micelle, where the micelle comprises a polymer-flavonoid conjugate, wherein said polymer is bonded to the B ring of said flavonoid. The micellar nanocomplex may have useful applications as a drug-delivery system.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: November 5, 2019
    Assignee: Agency for Science, Technology and Research
    Inventors: Motoichi Kurisawa, Yongvongsoontorn Nunnarpas, Jackie Y. Ying, Joo Eun Chung, Ki Hyun Bae, Min-Han Tan, Esther Lee
  • Patent number: 10468974
    Abstract: A method that prevents overload to input source and reduces parasitic inductance in an inverter circuit with dead-time control. A sensing capacitor senses temperatures of transistors in the inverter circuit. A delay generator changes delay times in response to receiving the temperatures of the transistors from the sensing capacitor. A dead time generation unit changes the dead times for the transistors in response to changes in the delay times.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: November 5, 2019
    Assignee: HONG KONG APPLIED SCIENCE AND TECHNOLOGY RESEARCH INSTITUTE COMPANY LIMITED
    Inventors: Hang Sang Lee, Yan Liu
  • Patent number: 10463580
    Abstract: A dental treatment method is provided. In this method, a tooth of a patient is extracted and prepared to provide a root part. A root canal in the extracted tooth is prepared and treated. A post of an abutment is fitted into the root canal to attach the root part to the abutment. The abutment having the root part is attached to a dental implant. With the root part attached to the abutment, periodontal connective tissue maintains the jaw bone associated with the extracted tooth, without significant hard tissue loss.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 5, 2019
    Assignee: The Research Foundation for The State University of New York
    Inventor: Marcus Abboud
  • Patent number: D865539
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: November 5, 2019
    Assignee: FIPAK Research And Development Company
    Inventors: Antoine Hauville, Cédric Herry, Stephane Hauville