Abstract: Provided herein are monoacylglycerol lipase (MGLL) occupancy probes comprising a MGLL inhibitor containing a positron emission tomography (PET) tracer radionuclide. Also provided are methods of assessing MGLL enzyme occupancy of a MGLL inhibitor using the radiolabeled occupancy probes described herein.

Abstract: A gas production apparatus is provided which includes: a module including a plurality of PN junctions connected in series to one another, each being formed of an inorganic semiconductor and having a light receiving surface; two gas generators that are provided at open ends of PN junctions at both extremities of the module, respectively, on a side of the light receiving surface; an electrolysis chamber which contains an aqueous electrolytic solution in contact with the two gas generators and contains gases generated by the two gas generators; and a diaphragm which is ion-permeable but gas-impermeable, and partitions the electrolysis chamber into two regions including the two gas generators, respectively, and containing hydrogen and oxygen, respectively.

Abstract: A computer-implemented tool having a collection of content management subsystems allows the content creator to construct a web-based behavioral modification site without the need for computer programming skills. The content delivery system constructed with this tool employs a lesson manager that delivers lesson content based on a tree structure; a virtual educator manager that presents different graphical images of an educator character, complete with different facial expressions and gestures designed to facilitate learning; a link manager that supplements lesson content with links to supplemental material and automatically suppresses dead links; and an impact manager that automatically administers a stage-of-change questionnaire a predefined time interval after the lesson was completed.

Abstract: A device has a hyperspectral imaging sensor including a polarizing device to receive and polarize an incoming beam of light, a liquid crystal variable retarder adjacent the polarizing device to receive the polarized beam of light from the polarizing device and to change polarization of the light in a wavelength dependent manner, an output polarizer to receive the wavelength-dependent polarized light and to convert polarization state information of the light into a form detectable as light intensity, a voltage source connected to the liquid crystal device, and a controller to control voltages applied to the liquid crystal variable retarder; an image sensor synchronized with the controller to receive the light in a form detectable as light intensity as a function of retardance of the liquid crystal variable retarder and convert the light to an output signal, and a processor to transform the output signal into spectral information.

Abstract: This invention relates to methods and compositions for treating fibrosis, by administering compositions comprising anti-LPS immunoglobulin enriched colostrum preparations. In particular, the invention relates to methods and compositions for the treatment of liver fibrosis and/or lung fibrosis. Prophylactic or therapeutic compositions and diagnostic methods are also disclosed and claimed.

Abstract: Crosslinkable random copolymers comprising atom transfer radical polymerization (ATRP) initiators and crosslinked copolymer films formed from the copolymers are provided. The random copolymers, which are polymerized from one or more alkyl halide functional inimers and one or more monomers having a crosslinkable functionality, are characterized by pendant ATRP initiating groups and pendant crosslinkable groups.

Abstract: A method and corresponding composition to inhibit outgrowth of C. difficile spores and/or to inhibit growth of C. difficile vegetative cells in a mammal in which an amount of a nylon-3 polymer or nylon-3 copolymer or a pharmaceutically suitable salt thereof is administered to the subject.

Abstract: An apparatus for applying an asphalt binder composition to a roadway during construction or repair of an asphalt pavement which apparatus include: a mobile vehicle having a chassis extending in a longitudinal direction which longitudinal direction is aligned with a forward/rearward direction of travel of said mobile vehicle; at least one storage tank supported on the chassis containing an asphalt binder composition; and at least one spray nozzle configured to dispense the asphalt binder composition from the at least one storage tank in a longitudinal strip or band having a width that is no greater that a width of the asphalt binder composition dispensed by one of the at least one spray nozzle. The at least one spray nozzle can include a plurality of spray nozzles that are coupled to a common spray bar. According to one embodiment the asphalt binder composition is a void reducing asphalt membrane composition that is provided between adjacent asphalt pavement passes.

Abstract: A visual privacy system unilaterally blocks rolling shutter cameras by providing a periodically interrupted ambient light source imposing bright and dark bands on the image yet at a frequency imperceptible to human observers in the environment. Communication of the modulation pattern to authorized cameras allows unaffected imaging in these regions by authorized individuals. The system also contemplates operation in a barcoding mode with a light modulation providing embedded barcodes that can be extracted from images taken in the region to indicate that the images were improperly acquired and to block the images in certain applications.

Abstract: Provided is a method of increasing an amount of coke-oven gas, including the step of: introducing steam into a gas way of a carbonization chamber of a coke oven such that a water-gas reaction is conducted at 500° C. or higher during a process of carbonizing coal in the carbonization chamber of the coke oven, wherein the starting point of steam into the gas way is moved up prior to a time point at which an amount of generation of coke-oven gas is maximized, so as to increase the steam introduction time, thereby maximizing a reaction of steam with carbon existing in the carbonization chamber of the coke oven.

Abstract: Methods and composition for nucleic acid isolation are provided. In one embodiment, the invention provides a method for nucleic acid purification from biological samples extracted with phenol-based denaturing solvents, which does not require phase separation or nucleic acid precipitation. Methods according to the invention may also be used for differential isolation of RNA and DNA.

Abstract: A method to make a phosphorus modified zeolite can include providing a zeolite having at least one ten member ring, making an ion-exchange, steaming the zeolite, and introducing phosphorus on the zeolite. The zeolite can be mixed with one or more binders and shaping additives, and then shaped. A metal can be introduced, and the catalyst can be washed, calcined, and steamed in an equilibration step. The steaming can be at performed at a steam severity (X) of at least about 2. The steaming can be performed at a temperature above 625° C. The catalyst can be used in alcohol dehydration, olefin cracking, MTO processes, and alkylation of aromatics by alcohols with olefins and/or alcohols.

Abstract: Carbon nanotube (CNT) forests or sheets coated and/or bonded at room temperature with one or more coatings were measured to produce thermal resistances that are on par with conventional metallic solders. These results were achieved by reducing the high contact resistance at CNT tips and/or sidewalls, which has encumbered the development of high-performance thermal interface materials based on CNTs. Resistances as low as 4.9±0.3 mm2?K/W were achieved for the entire polymer-coated CNT interface structure.

Abstract: Compositions and methods for treating cancer in a subject in need thereof are described that includes administering a therapeutically effective amount of an oligonucleotide that inhibits the binding of splicing regulator SRSF1 or SRSF2 to MDM2 exon 4 or 11.

Abstract: An energy-absorbing knee bolster frame (10) for a vehicle (1) comprises a longitudinal knee contact member (20), a first energy-absorbing transverse bracket member (30) and a second energy-absorbing transverse bracket member (40). The first energy-absorbing transverse bracket member (30) and the second energy-absorbing transverse bracket member (40) extend in a transverse direction (Y) and are spaced apart on the longitudinal knee contact member (20). The longitudinal knee contact member (20) has a knee contact surface (22) for receiving a part of a knee (80) of an occupant (P) upon a collision. The first energy-absorbing transverse bracket member (30) has a cross section defining an open profile, and is adapted at one end (32) to engage with a vehicle interior component (100), and includes a plurality of first deformation segments (34A-N) configured for absorbing energy generated by a knee impact.

Abstract: A method for estimating efficiency of a particulate filter of a vehicle is provided. The method includes: calculating a first estimated value representing an amount of particulate matters (PM) accumulated in the particulate filter; upon determining to perform regeneration of the particulate filter based on the first estimated value, injecting fuel into the particulate filter and combusting the PM; calculating a second estimated value representing an amount of particulate matters accumulated in the particulate filter after the regeneration; and determining whether a PM accumulation condition of the particulate filter requires user attention based on the second estimated value.

Abstract: The present disclosure relates to an apparatus for measuring a thickness and a surface profile of a multilayered film structure using an imaging spectral optical system and a measuring method. More specifically, the present disclosure relates to a method and an apparatus which measure a thickness and a surface profile of a multilayered thin film structure by applying a method for obtaining an absolute reflectance value for an object to be measured having a multilayered thin film using a reflected light measuring method and extracting a phase from an interference signal with a reference mirror using a phase shift algorithm.

Abstract: An automated method for remote computing of molecular docking and dynamics from one or more jobs in a network of plurality of users. The invention employs a system to execute the method comprising at least one user device, a remote computing server and a remote database. The job defining action tags are received and scanned by the remote server. A semantic analysis is performed on the jobs to distinguish between customized and non-customized tasks. A data analysis of the jobs is packaged in a compressed format. The user is continually updated of the job status. A public link is generated and sent to the user to download the results. The link is disabled after the downloading of the results to ensure the security of the data. The method avoids any duplication of jobs and can be performed even when the user is offline.

Abstract: A roller includes a cylindrical outer surface of a hydrophobic material, an inner core of a hydrophilic material, and an inhomogeneous geometric pattern of grooves in the surface that expose the hydrophilic material. A method of manufacturing a roller, includes providing a cylindrical core of a hydrophilic material, covering the cylindrical core with a hydrophobic surface, creating grooves in the hydrophobic surface to form a geometrically inhomogeneous pattern of the hydrophilic material. A method of manufacturing a roller, includes forming a pattern of geometrically inhomogeneous grooves on a hydrophobic core, functionalizing the surface to make the surface hydrophilic, and removing a portion of a top layer of the hydrophobic core to expose the hydrophobic core, leaving hydrophilic grooves.

Abstract: A method of controlling discovery signal communication of a user equipment (UE) and a UE using the same is disclosed. The method comprises steps of selecting a target operating radio resource associated with the discovery signal communication among a plurality of discovery radio resources to transmit at least one discovery signal of the UE, and updating the target operating radio resource by the UE based on a loading of the plurality of discovery radio resources calculated by the UE.